Experiment set84S237 for Escherichia coli BW25113

Compare to:

Bas79

200 most important genes:

  gene name fitness t score description  
b0049 apaH -2.7 -3.7 diadenosinetetraphosphatase (NCBI) compare
b4503 yafF -2.7 -1.6 no description compare
b4202 rpsR -2.7 -2.6 30S ribosomal protein S18 (NCBI) compare
b3390 aroK -2.6 -3.1 shikimate kinase I (NCBI) compare
b1882 cheY -2.6 -1.0 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b3341 rpsG -2.5 -2.2 30S ribosomal protein S7 (NCBI) compare
b3021 ygiT -2.4 -2.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b1361 ydaW -2.3 -0.9 orf, hypothetical protein (VIMSS) compare
b1863 ruvC -2.2 -3.3 Holliday junction resolvase (NCBI) compare
b0683 fur -2.2 -1.5 ferric uptake regulator (NCBI) compare
b0738 tolR -2.2 -2.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2168 fruK -1.9 -1.5 1-phosphofructokinase (NCBI) compare
b3405 ompR -1.8 -5.1 osmolarity response regulator (NCBI) compare
b0053 surA -1.7 -4.0 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3619 rfaD -1.7 -3.2 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b2894 xerD -1.7 -1.1 site-specific tyrosine recombinase XerD (NCBI) compare
b1192 ldcA -1.7 -4.6 L,D-carboxypeptidase A (NCBI) compare
b1861 ruvA -1.7 -1.8 Holliday junction DNA helicase motor protein (NCBI) compare
b3026 qseC -1.6 -2.7 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0739 tolA -1.6 -2.4 cell envelope integrity inner membrane protein TolA (NCBI) compare
b4647 mokA -1.6 -1.1 no description compare
b0888 trxB -1.6 -3.8 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3778 rep -1.5 -7.5 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1293 sapB -1.5 -1.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3183 obgE -1.5 -1.0 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4585 sroB -1.5 -1.6 Novel sRNA, function unknown (RefSeq) compare
b3863 polA -1.5 -1.7 DNA polymerase I (NCBI) compare
b1290 sapF -1.5 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3205 yhbJ -1.4 -3.9 hypothetical protein (NCBI) compare
b1628 rsxB -1.4 -3.7 electron transport complex protein RnfB (NCBI) compare
b3839 tatC -1.4 -5.5 TatABCE protein translocation system subunit (NCBI) compare
b3621 rfaC -1.4 -4.5 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1648 b1648 -1.3 -1.9 orf, hypothetical protein (VIMSS) compare
b3781 trxA -1.3 -3.0 thioredoxin 1 (VIMSS) compare
b1573 ydfC -1.3 -2.0 Qin prophage; predicted protein (RefSeq) compare
b3387 dam -1.2 -8.2 DNA adenine methylase (NCBI) compare
b0437 clpP -1.2 -4.7 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b4570 lomR -1.2 -1.1 no description compare
b0688 pgm -1.2 -2.9 phosphoglucomutase (NCBI) compare
b3636 rpmG -1.2 -1.6 50S ribosomal protein L33 (NCBI) compare
b0439 lon -1.2 -4.1 DNA-binding ATP-dependent protease La (NCBI) compare
b2017 yefM -1.2 -1.9 orf, hypothetical protein (VIMSS) compare
b3816 corA -1.1 -5.7 magnesium/nickel/cobalt transporter (NCBI) compare
b4294 insA-7 -1.1 -2.1 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b4191 ulaR -1.1 -2.6 DNA-binding transcriptional dual regulator (NCBI) compare
b1566 flxA -1.1 -2.6 Qin prophage; predicted protein (NCBI) compare
b0740 tolB -1.1 -2.2 translocation protein TolB precursor (NCBI) compare
b3792 wzxE -1.1 -5.4 O-antigen translocase (NCBI) compare
b2642 yfjW -1.1 -1.0 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1286 rnb -1.1 -2.0 exoribonuclease II (NCBI) compare
b1160 elbA -1.1 -1.0 hypothetical protein (NCBI) compare
b4414 tff -1.1 -1.8 unknown RNA (NCBI) compare
b0890 ftsK -1.0 -2.9 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0200 gmhB -1.0 -1.0 hypothetical protein (NCBI) compare
b2287 nuoB -1.0 -3.1 NADH dehydrogenase subunit B (NCBI) compare
b3250 mreC -1.0 -1.7 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b4146 yjeK -1.0 -0.7 predicted lysine aminomutase (NCBI) compare
b3052 rfaE -1.0 -3.7 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3791 rffA -1.0 -5.1 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1942 fliJ -1.0 -1.4 flagellar biosynthesis chaperone (NCBI) compare
b2282 nuoH -1.0 -2.3 NADH dehydrogenase subunit H (NCBI) compare
b1346 ydaQ -1.0 -1.3 orf, hypothetical protein (VIMSS) compare
b3620 rfaF -1.0 -3.3 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3181 greA -0.9 -2.3 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b2808 gcvA -0.9 -2.7 DNA-binding transcriptional dual regulator (NCBI) compare
b0741 pal -0.9 -2.2 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3169 nusA -0.9 -2.5 transcription elongation factor NusA (NCBI) compare
b2195 ccmG -0.9 -2.7 periplasmic thioredoxin of cytochrome c-type biogenesis (NCBI) compare
b3935 priA -0.9 -1.5 primosome assembly protein PriA (NCBI) compare
b3229 sspA -0.9 -2.0 stringent starvation protein A (NCBI) compare
b0263 afuB -0.9 -1.7 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b1847 yebF -0.9 -1.5 predicted protein (RefSeq) compare
b2814 metZ -0.9 -1.4 tRNA-Met (NCBI) compare
b3465 yhhF -0.9 -4.0 predicted methyltransferase (NCBI) compare
b0912 ihfB -0.9 -2.1 integration host factor subunit beta (NCBI) compare
b1685 ydiH -0.9 -1.3 predicted protein (RefSeq) compare
b1175 minD -0.9 -3.0 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2419 yfeK -0.9 -2.0 hypothetical protein (NCBI) compare
b0145 dksA -0.9 -2.1 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1219 ychN -0.9 -3.3 hypothetical protein (NCBI) compare
b2897 ygfY -0.9 -3.1 hypothetical protein (NCBI) compare
b2846 yqeH -0.8 -0.5 orf, hypothetical protein (VIMSS) compare
b1712 ihfA -0.8 -1.2 integration host factor subunit alpha (NCBI) compare
b1551 b1551 -0.8 -0.5 orf, hypothetical protein (VIMSS) compare
b0149 mrcB -0.8 -6.1 penicillin-binding protein 1b (NCBI) compare
b4529 ydbJ -0.8 -0.8 hypothetical protein (NCBI) compare
b3741 gidA -0.8 -1.9 glucose-inhibited division protein A (NCBI) compare
b2340 sixA -0.8 -3.1 phosphohistidine phosphatase (NCBI) compare
b1550 b1550 -0.8 -1.1 orf, hypothetical protein (VIMSS) compare
b3164 pnp -0.8 -2.0 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3916 pfkA -0.8 -1.2 6-phosphofructokinase (NCBI) compare
b4203 rplI -0.8 -2.1 50S ribosomal protein L9 (NCBI) compare
b4201 priB -0.8 -1.2 primosomal replication protein N (NCBI) compare
b1686 ydiI -0.8 -1.4 hypothetical protein (NCBI) compare
b4603 rseX -0.8 -0.6 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b1709 btuD -0.8 -0.8 vitamin B12-transporter ATPase (NCBI) compare
b0928 aspC -0.8 -4.6 aspartate aminotransferase, PLP-dependent (NCBI) compare
b4551 yheV -0.8 -2.0 hypothetical protein (NCBI) compare
b0340 cynS -0.8 -2.9 cyanate hydratase (NCBI) compare
b0018 mokC -0.8 -1.0 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b0386 proC -0.7 -2.5 pyrroline-5-carboxylate reductase (NCBI) compare
b0161 degP -0.7 -3.8 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b1182 hlyE -0.7 -0.5 hemolysin E (VIMSS) compare
b3842 rfaH -0.7 -2.7 transcriptional activator RfaH (NCBI) compare
b1105 ycfM -0.7 -2.6 predicted outer membrane lipoprotein (NCBI) compare
b0902 pflA -0.7 -3.8 pyruvate formate lyase activating enzyme 1 (NCBI) compare
b1279 yciS -0.7 -0.8 conserved inner membrane protein (NCBI) compare
b3613 yibP -0.7 -1.5 putative membrane protein (VIMSS) compare
b2284 nuoF -0.7 -2.7 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b1292 sapC -0.7 -1.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3652 recG -0.7 -4.5 ATP-dependent DNA helicase (NCBI) compare
b1291 sapD -0.7 -1.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1383 ydbL -0.7 -1.8 orf, hypothetical protein (VIMSS) compare
b3162 deaD -0.7 -2.5 inducible ATP-independent RNA helicase (VIMSS) compare
b1070 flgN -0.7 -1.0 export chaperone for FlgK and FlgL (NCBI) compare
b0870 ltaE -0.7 -3.5 L-allo-threonine aldolase, PLP-dependent (NCBI) compare
b0767 ybhE -0.7 -1.8 6-phosphogluconolactonase (NCBI) compare
b2145 yeiS -0.7 -1.9 predicted inner membrane protein (NCBI) compare
b4509 ylcG -0.7 -2.0 DLP12 prophage; predicted protein (NCBI) compare
b3623 rfaK -0.7 -1.3 lipopolysaccharide core biosynthesis (NCBI) compare
b3210 arcB -0.7 -3.9 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b2281 nuoI -0.7 -1.9 NADH dehydrogenase subunit I (NCBI) compare
b4557 yidD -0.7 -2.4 hypothetical protein (NCBI) compare
b2617 smpA -0.7 -1.5 small membrane protein A (VIMSS) compare
b3237 argR -0.7 -2.2 arginine repressor (NCBI) compare
b1503 ydeR -0.7 -2.0 predicted fimbrial-like adhesin protein (NCBI) compare
b3706 trmE -0.7 -2.2 tRNA modification GTPase (NCBI) compare
b2277 nuoM -0.7 -2.9 NADH dehydrogenase subunit M (NCBI) compare
b2501 ppk -0.7 -4.0 polyphosphate kinase (NCBI) compare
b2188 yejM -0.7 -4.6 predicted hydrolase, inner membrane (NCBI) compare
b0737 tolQ -0.7 -1.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4577 sgrS -0.6 -1.0 small antisense RNA (NCBI) compare
b2329 aroC -0.6 -2.4 chorismate synthase (NCBI) compare
b1258 yciF -0.6 -0.7 hypothetical protein (NCBI) compare
b2947 gshB -0.6 -1.9 glutathione synthetase (NCBI) compare
b2445 yffN -0.6 -2.4 CPZ-55 prophage; predicted protein (RefSeq) compare
b1855 lpxM -0.6 -2.4 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0677 nagA -0.6 -2.6 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b0222 lpcA -0.6 -1.4 phosphoheptose isomerase (NCBI) compare
b1658 purR -0.6 -2.6 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b3226 yhcK -0.6 -2.8 putative FADA-type transcriptional regulator (VIMSS) compare
b1161 ycgX -0.6 -0.7 hypothetical protein (NCBI) compare
b0535 fimZ -0.6 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b4319 fimG -0.6 -3.1 minor component of type 1 fimbriae (NCBI) compare
b3871 bipA -0.6 -3.6 GTP-binding protein (NCBI) compare
b1236 galU -0.6 -2.2 glucose-1-phosphate uridylyltransferase (NCBI) compare
b2175 spr -0.6 -2.6 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b0782 moaB -0.6 -1.3 molybdopterin biosynthesis protein B (NCBI) compare
b1607 ydgC -0.6 -0.9 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b0438 clpX -0.6 -3.0 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1357 ydaS -0.6 -1.0 Rac prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b4041 plsB -0.6 -1.2 glycerol-3-phosphate acyltransferase (VIMSS) compare
b2830 nudH -0.6 -0.6 dinucleoside polyphosphate hydrolase (NCBI) compare
b0088 murD -0.6 -1.6 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b1693 aroD -0.6 -2.2 3-dehydroquinate dehydratase (NCBI) compare
b4184 yjfL -0.6 -2.4 conserved inner membrane protein (NCBI) compare
b1143 ymfI -0.6 -1.1 orf, hypothetical protein (VIMSS) compare
b4552 yrhC -0.6 -0.5 no description compare
b0051 ksgA -0.6 -1.9 dimethyladenosine transferase (NCBI) compare
b2110 yehC -0.6 -0.5 predicted periplasmic pilin chaperone (NCBI) compare
b2276 nuoN -0.6 -2.1 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b4481 rffT -0.6 -2.4 4-alpha-L-fucosyltransferase (NCBI) compare
b4593 ymgI -0.6 -0.6 hypothetical protein (RefSeq) compare
b2659 b2659 -0.6 -1.4 orf, hypothetical protein (VIMSS) compare
b0234 yafP -0.6 -0.4 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b4418 sraB -0.6 -1.3 unknown RNA (NCBI) compare
b1799 yeaT -0.6 -2.3 putative transcriptional regulator LYSR-type (VIMSS) compare
b0407 yajC -0.6 -1.4 preprotein translocase subunit YajC (NCBI) compare
b0632 dacA -0.6 -3.3 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b1811 yoaH -0.6 -2.1 hypothetical protein (NCBI) compare
b3404 envZ -0.6 -3.4 osmolarity sensor protein (NCBI) compare
b4312 fimB -0.6 -4.0 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b1567 intK -0.6 -1.5 Qin prophage; predicted protein (RefSeq) compare
b3035 tolC -0.6 -3.6 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3811 xerC -0.6 -0.8 site-specific tyrosine recombinase XerC (NCBI) compare
b3629 rfaS -0.6 -1.7 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1438 ydcQ -0.6 -1.8 predicted DNA-binding transcriptional regulator (RefSeq) compare
b3911 cpxA -0.5 -4.0 two-component sensor protein (NCBI) compare
b0364 yaiS -0.5 -1.6 orf, hypothetical protein (VIMSS) compare
b1961 dcm -0.5 -1.0 DNA cytosine methylase (NCBI) compare
b3107 yhaL -0.5 -0.9 orf, hypothetical protein (VIMSS) compare
b3545 proK -0.5 -1.3 tRNA-Pro (NCBI) compare
b4644 ypjI -0.5 -1.8 no description compare
b1754 b1754 -0.5 -1.3 orf, hypothetical protein (VIMSS) compare
b2278 nuoL -0.5 -3.3 NADH dehydrogenase subunit L (NCBI) compare
b4567 yjjZ -0.5 -1.7 hypothetical protein (NCBI) compare
b1506 yneL -0.5 -1.0 predicted transcriptional regulator (NCBI) compare
b0724 sdhB -0.5 -2.8 succinate dehydrogenase, FeS subunit (NCBI) compare
b3389 aroB -0.5 -2.9 3-dehydroquinate synthase (NCBI) compare
b1129 phoQ -0.5 -0.7 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b0881 clpS -0.5 -1.1 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b1414 ydcF -0.5 -2.6 hypothetical protein (NCBI) compare
b2784 relA -0.5 -3.4 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b1591 b1591 -0.5 -0.9 putative oxidoreductase component (VIMSS) compare
b2363 yfdT -0.5 -1.2 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b2820 recB -0.5 -0.4 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0249 ykfF -0.5 -1.7 CP4-6 prophage; predicted protein (NCBI) compare
b1256 ompW -0.5 -3.4 outer membrane protein W (NCBI) conserved
b0216 aspV -0.5 -2.2 tRNA-Asp (NCBI) compare
b1821 b1821 -0.5 -1.6 orf, hypothetical protein (VIMSS) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in phage experiments

For phage Phage across organisms