Experiment set84S228 for Escherichia coli BW25113

Compare to:

Bas90

200 most important genes:

  gene name fitness t score description  
b1863 ruvC -3.9 -3.8 Holliday junction resolvase (NCBI) compare
b4202 rpsR -3.4 -2.3 30S ribosomal protein S18 (NCBI) compare
b3021 ygiT -3.0 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b0142 folK -3.0 -1.2 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b2620 smpB -2.5 -1.7 SsrA-binding protein (NCBI) compare
b1860 ruvB -2.5 -1.7 Holliday junction DNA helicase B (NCBI) compare
b0683 fur -2.4 -2.3 ferric uptake regulator (NCBI) compare
b1550 b1550 -2.3 -2.4 orf, hypothetical protein (VIMSS) compare
b1291 sapD -2.2 -2.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0738 tolR -2.1 -2.4 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3341 rpsG -1.9 -1.7 30S ribosomal protein S7 (NCBI) compare
b3082 ygjM -1.9 -2.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b2894 xerD -1.9 -1.2 site-specific tyrosine recombinase XerD (NCBI) compare
b2830 nudH -1.8 -1.2 dinucleoside polyphosphate hydrolase (NCBI) compare
b2939 yqgB -1.8 -2.0 predicted protein (RefSeq) compare
b2567 rnc -1.8 -1.2 ribonuclease III (NCBI) compare
b3816 corA -1.8 -7.1 magnesium/nickel/cobalt transporter (NCBI) compare
b0053 surA -1.7 -4.5 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1861 ruvA -1.6 -1.8 Holliday junction DNA helicase motor protein (NCBI) compare
b1573 ydfC -1.6 -1.9 Qin prophage; predicted protein (RefSeq) compare
b3390 aroK -1.5 -2.9 shikimate kinase I (NCBI) compare
b1607 ydgC -1.5 -1.5 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b0890 ftsK -1.4 -3.2 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0730 mngR -1.4 -1.9 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b1236 galU -1.4 -4.4 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1104 ycfL -1.4 -2.1 hypothetical protein (NCBI) compare
b2444 yffM -1.3 -3.0 CPZ-55 prophage; predicted protein (NCBI) compare
b0222 lpcA -1.3 -2.4 phosphoheptose isomerase (NCBI) compare
b1160 elbA -1.3 -1.2 hypothetical protein (NCBI) compare
b3977 tyrU -1.3 -0.7 tRNA-Tyr (NCBI) compare
b0439 lon -1.3 -4.9 DNA-binding ATP-dependent protease La (NCBI) compare
b1476 fdnI -1.3 -1.0 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b0049 apaH -1.2 -2.6 diadenosinetetraphosphatase (NCBI) compare
b1429 tehA -1.2 -1.3 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b4552 yrhC -1.2 -0.7 no description compare
b4503 yafF -1.2 -0.9 no description compare
b1677 lpp -1.2 -3.2 murein lipoprotein (NCBI) compare
b3619 rfaD -1.1 -3.2 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3405 ompR -1.1 -3.5 osmolarity response regulator (NCBI) compare
b3250 mreC -1.1 -2.0 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b1942 fliJ -1.1 -1.6 flagellar biosynthesis chaperone (NCBI) compare
b0888 trxB -1.1 -3.2 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b4414 tff -1.1 -2.3 unknown RNA (NCBI) compare
b3916 pfkA -1.1 -1.3 6-phosphofructokinase (NCBI) compare
b4191 ulaR -1.1 -3.2 DNA-binding transcriptional dual regulator (NCBI) compare
b3162 deaD -1.1 -3.8 inducible ATP-independent RNA helicase (VIMSS) compare
b4653 yicT -1.0 -1.2 no description compare
b3052 rfaE -1.0 -3.6 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3863 polA -1.0 -1.3 DNA polymerase I (NCBI) compare
b3107 yhaL -1.0 -1.6 orf, hypothetical protein (VIMSS) compare
b3778 rep -1.0 -5.1 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1551 b1551 -1.0 -0.6 orf, hypothetical protein (VIMSS) compare
b0989 cspH -1.0 -2.2 stress protein, member of the CspA-family (NCBI) compare
b1847 yebF -1.0 -1.5 predicted protein (RefSeq) compare
b2846 yqeH -1.0 -0.6 orf, hypothetical protein (VIMSS) compare
b4529 ydbJ -0.9 -0.9 hypothetical protein (NCBI) compare
b4685 yrbN -0.9 -2.4 expressed protein (RefSeq) compare
b3164 pnp -0.9 -2.3 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3237 argR -0.9 -2.6 arginine repressor (NCBI) compare
b3871 bipA -0.9 -5.9 GTP-binding protein (NCBI) compare
b1493 gadB -0.9 -1.0 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b1143 ymfI -0.9 -2.2 orf, hypothetical protein (VIMSS) compare
b3706 trmE -0.9 -2.8 tRNA modification GTPase (NCBI) compare
b2282 nuoH -0.9 -2.4 NADH dehydrogenase subunit H (NCBI) compare
b4402 yjjY -0.9 -0.8 hypothetical protein (NCBI) compare
b2953 yggU -0.9 -2.2 orf, hypothetical protein (VIMSS) compare
b0630 lipB -0.9 -0.6 protein of lipoate biosynthesis (VIMSS) compare
b4631 ykgQ -0.9 -1.3 no description compare
b0990 cspG -0.9 -0.6 DNA-binding transcriptional regulator (NCBI) compare
b1730 ydjO -0.9 -1.1 predicted protein (RefSeq) compare
b0549 ybcO -0.9 -2.0 DLP12 prophage; predicted protein (NCBI) compare
b0912 ihfB -0.9 -2.8 integration host factor subunit beta (NCBI) compare
b3426 glpD -0.8 -1.8 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b0767 ybhE -0.8 -2.9 6-phosphogluconolactonase (NCBI) compare
b3414 gntY -0.8 -3.9 predicted gluconate transport associated protein (NCBI) compare
b1951 rcsA -0.8 -1.2 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b2017 yefM -0.8 -0.9 orf, hypothetical protein (VIMSS) compare
b2343 b2343 -0.8 -1.5 orf, hypothetical protein (VIMSS) compare
b4522 yciX_1 -0.8 -2.0 hypothetical protein (NCBI) compare
b4042 dgkA -0.8 -1.4 diacylglycerol kinase (NCBI) compare
b2363 yfdT -0.8 -1.7 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b4146 yjeK -0.8 -1.0 predicted lysine aminomutase (NCBI) compare
b1506 yneL -0.8 -1.1 predicted transcriptional regulator (NCBI) compare
b2287 nuoB -0.8 -1.7 NADH dehydrogenase subunit B (NCBI) compare
b3792 wzxE -0.8 -4.1 O-antigen translocase (NCBI) compare
b2168 fruK -0.8 -0.9 1-phosphofructokinase (NCBI) compare
b2283 nuoG -0.8 -3.7 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b1628 rsxB -0.8 -1.4 electron transport complex protein RnfB (NCBI) compare
b4294 insA-7 -0.8 -2.1 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b1478 adhP -0.8 -2.3 alcohol dehydrogenase (VIMSS) compare
b1138 ymfE -0.8 -1.2 e14 prophage; predicted inner membrane protein (NCBI) compare
b1175 minD -0.8 -2.4 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b3613 yibP -0.8 -1.7 putative membrane protein (VIMSS) compare
b0149 mrcB -0.8 -5.6 penicillin-binding protein 1b (NCBI) compare
b4592 yccB -0.7 -1.2 hypothetical protein (RefSeq) compare
b2289 lrhA -0.7 -5.1 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) compare
b3811 xerC -0.7 -1.0 site-specific tyrosine recombinase XerC (NCBI) compare
b1712 ihfA -0.7 -1.2 integration host factor subunit alpha (NCBI) compare
b4369 leuP -0.7 -1.2 tRNA-Leu (NCBI) compare
b0858 ybjO -0.7 -1.7 predicted inner membrane protein (NCBI) compare
b1620 malI -0.7 -1.6 DNA-binding transcriptional repressor (NCBI) compare
b0438 clpX -0.7 -3.5 ATP-dependent protease ATP-binding subunit (NCBI) compare
b2646 ypjF -0.7 -1.8 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b0386 proC -0.7 -2.5 pyrroline-5-carboxylate reductase (NCBI) compare
b1686 ydiI -0.7 -1.8 hypothetical protein (NCBI) compare
b3625 rfaY -0.7 -2.7 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1567 intK -0.7 -1.6 Qin prophage; predicted protein (RefSeq) compare
b0706 ybfD -0.7 -1.6 hypothetical protein (NCBI) compare
b4593 ymgI -0.7 -0.8 hypothetical protein (RefSeq) compare
b2281 nuoI -0.7 -1.1 NADH dehydrogenase subunit I (NCBI) compare
b3493 pitA -0.7 -3.7 phosphate transporter, low-affinity (NCBI) compare
b3806 cyaA -0.7 -2.9 adenylate cyclase (NCBI) compare
b3387 dam -0.7 -4.9 DNA adenine methylase (NCBI) compare
b3229 sspA -0.7 -1.8 stringent starvation protein A (NCBI) compare
b0763 modA -0.7 -2.7 molybdate transporter subunit (NCBI) compare
b1618 uidR -0.7 -1.8 DNA-binding transcriptional repressor (NCBI) compare
b0739 tolA -0.6 -1.5 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0437 clpP -0.6 -2.5 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b1108 ycfP -0.6 -1.5 orf, hypothetical protein (VIMSS) compare
b4171 miaA -0.6 -1.9 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b2285 nuoE -0.6 -1.1 NADH dehydrogenase subunit E (NCBI) compare
b0802 ybiJ -0.6 -1.4 hypothetical protein (NCBI) compare
b4676 yoaK -0.6 -0.3 expressed protein (RefSeq) compare
b4613 dinQ -0.6 -1.3 Damage inducible, function unknown (RefSeq) compare
b1121 ycfZ -0.6 -1.1 predicted inner membrane protein (NCBI) compare
b4375 prfC -0.6 -2.7 peptide chain release factor 3 (NCBI) compare
b1514 lsrC -0.6 -1.1 AI2 transporter (NCBI) compare
b3026 qseC -0.6 -1.8 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b2666 yqaE -0.6 -2.5 predicted membrane protein (NCBI) compare
b3781 trxA -0.6 -2.6 thioredoxin 1 (VIMSS) compare
b1242 ychE -0.6 -3.0 predicted inner membrane protein (NCBI) compare
b1855 lpxM -0.6 -2.0 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b2105 yohL -0.6 -1.4 hypothetical protein (NCBI) compare
b2450 yffS -0.6 -0.8 CPZ-55 prophage; predicted protein (RefSeq) compare
b1040 csgD -0.6 -0.9 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b3181 greA -0.6 -2.7 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b2820 recB -0.6 -0.4 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0737 tolQ -0.6 -1.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0791 ybhQ -0.6 -2.0 predicted inner membrane protein (NCBI) compare
b3621 rfaC -0.6 -2.5 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1482 osmC -0.6 -0.9 osmotically inducible, stress-inducible membrane protein (NCBI) compare
b1074 flgC -0.6 -1.5 flagellar basal-body rod protein C (NCBI) compare
b0251 yafY -0.6 -1.4 CP4-6 prophage; predicted DNA-binding transcriptional regulator (RefSeq) compare
b2330 yfcB -0.6 -1.1 putative adenine-specific methylase (VIMSS) compare
b3649 rpoZ -0.6 -2.0 DNA-directed RNA polymerase subunit omega (NCBI) compare
b0357 yaiN -0.6 -1.4 putative alpha helix chain (VIMSS) compare
b0082 mraW -0.6 -1.3 S-adenosyl-methyltransferase (NCBI) compare
b0412 yajI -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b1253 yciA -0.6 -1.5 predicted hydrolase (NCBI) compare
b1739 osmE -0.6 -1.2 DNA-binding transcriptional activator (NCBI) compare
b2007 yeeX -0.6 -1.5 conserved protein (RefSeq) compare
b3210 arcB -0.6 -3.5 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b1438 ydcQ -0.6 -1.5 predicted DNA-binding transcriptional regulator (RefSeq) compare
b2804 fucU -0.6 -1.9 L-fucose mutarotase (NCBI) compare
b2897 ygfY -0.6 -1.5 hypothetical protein (NCBI) compare
b1165 ymgA -0.6 -0.4 hypothetical protein (NCBI) compare
b2565 recO -0.6 -2.4 DNA repair protein RecO (NCBI) compare
b2288 nuoA -0.6 -1.4 NADH dehydrogenase I chain A (VIMSS) compare
b0088 murD -0.6 -1.3 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b4506 ykgO -0.6 -1.8 rpmJ (L36) paralog (NCBI) compare
b1566 flxA -0.6 -1.5 Qin prophage; predicted protein (NCBI) compare
b1088 yceD -0.5 -1.6 hypothetical protein (NCBI) compare
b0548 ninE -0.5 -1.4 DLP12 prophage; conserved protein (NCBI) compare
b1084 rne -0.5 -2.2 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b4546 ypeB -0.5 -0.8 hypothetical protein (NCBI) compare
b4557 yidD -0.5 -2.1 hypothetical protein (NCBI) compare
b1613 manA -0.5 -1.1 mannose-6-phosphate isomerase (VIMSS) compare
b3169 nusA -0.5 -0.7 transcription elongation factor NusA (NCBI) compare
b3623 rfaK -0.5 -1.2 lipopolysaccharide core biosynthesis (NCBI) compare
b3404 envZ -0.5 -3.4 osmolarity sensor protein (NCBI) compare
b1679 sufE -0.5 -2.0 cysteine desufuration protein SufE (NCBI) compare
b3484 yhhI -0.5 -1.7 predicted transposase (NCBI) compare
b1920 fliY -0.5 -1.4 cystine transporter subunit (NCBI) compare
b0611 rna -0.5 -2.2 ribonuclease I (NCBI) compare
b2113 mrp -0.5 -2.0 putative ATPase (VIMSS) compare
b2286 nuoC -0.5 -2.0 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b1548 nohA -0.5 -1.1 Qin prophage; predicted packaging protein (RefSeq) compare
b2822 recC -0.5 -2.1 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b0822 ybiV -0.5 -2.3 predicted hydrolase (NCBI) compare
b1307 pspD -0.5 -1.1 peripheral inner membrane phage-shock protein (NCBI) compare
b2824 ygdB -0.5 -1.6 orf, hypothetical protein (VIMSS) compare
b4177 purA -0.5 -0.3 adenylosuccinate synthetase (NCBI) compare
b1518 lsrG -0.5 -1.2 autoinducer-2 (AI-2) modifying protein LsrG (NCBI) compare
b2698 recX -0.5 -1.5 RecA regulator RecX (NCBI) compare
b2393 nupC -0.5 -2.6 nucleoside (except guanosine) transporter (NCBI) compare
b0051 ksgA -0.5 -1.7 dimethyladenosine transferase (NCBI) compare
b3609 secB -0.5 -1.1 export protein SecB (NCBI) compare
b1709 btuD -0.5 -0.5 vitamin B12-transporter ATPase (NCBI) compare
b2280 nuoJ -0.5 -1.6 NADH dehydrogenase subunit J (NCBI) compare
b1103 ycfF -0.5 -0.9 orf, hypothetical protein (VIMSS) compare
b1693 aroD -0.5 -2.1 3-dehydroquinate dehydratase (NCBI) compare
b1366 ydaY -0.5 -2.2 Rac prophage; predicted protein (RefSeq) compare
b0219 yafV -0.5 -1.8 predicted C-N hydrolase family amidase, NAD(P)-binding (NCBI) compare
b0928 aspC -0.5 -2.5 aspartate aminotransferase, PLP-dependent (NCBI) compare
b1461 ydcE -0.5 -1.5 4-oxalocrotonate tautomerase (NCBI) compare
b1041 csgB -0.5 -2.0 curlin nucleator protein, minor subunit in curli complex (NCBI) compare
b0125 hpt -0.5 -2.6 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b1358 ydaT -0.5 -0.5 Rac prophage; predicted protein (NCBI) compare
b1235 rssB -0.5 -2.4 response regulator of RpoS (NCBI) compare
b1387 maoC -0.5 -2.4 fused aldehyde dehydrogenase/enoyl-CoA hydratase (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in phage experiments

For phage Phage across organisms