Experiment set7S44 for Escherichia coli BL21

Compare to:

Laval1261

200 most detrimental genes:

  gene name fitness t score description  
ECD_03132 +1.4 2.4 dehydroshikimate reductase, NAD(P)-binding compare
ECD_01403 +1.1 2.9 DUF2526 family protein compare
ECD_00450 +1.1 2.1 conserved protein, rhs-like protein compare
ECD_00388 +1.0 5.0 proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine proteases compare
ECD_02162 +1.0 2.3 ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance compare
ECD_02027 +1.0 2.3 ADP-ribosylglycohydrolase family protein compare
ECD_02474 +1.0 3.5 uracil-DNA-glycosylase compare
ECD_03023 +0.9 3.2 GNAT family putative N-acetyltransferase compare
ECD_00835 +0.9 2.6 hypothetical protein compare
ECD_01912 +0.9 2.2 DNA gyrase inhibitor compare
ECD_02054 +0.8 1.9 putative response regulator in two-component system withYehU compare
ECD_04030 +0.8 1.6 phosphatidylserine decarboxylase compare
ECD_02258 +0.8 2.2 putative fimbrial-like adhesin protein compare
ECD_01107 +0.8 2.1 repressor for bhsA(ycfR) compare
ECD_02919 +0.8 2.4 motility and biofilm regulator compare
ECD_02048 +0.8 2.2 putative hexameric AAA+ MoxR family ATPase compare
ECD_01404 +0.8 1.6 DUF606 family inner membrane protein compare
ECD_02297 +0.8 1.2 putative enzyme IIB component of PTS compare
ECD_01615 +0.8 2.9 putative efflux protein (PET) component of YdhJK efflux pump compare
ECD_02124 +0.7 2.6 periplasmic heme chaperone compare
ECD_00326 +0.7 1.3 DUF2755 family inner membrane protein compare
ECD_01925 +0.7 1.7 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
ECD_03727 +0.7 1.7 aerobic ubiquinone synthesis protein, SCP2 family protein compare
ECD_01657 +0.7 2.4 UPF0118 family inner membrane protein compare
ECD_03668 +0.7 3.5 TDP-fucosamine acetyltransferase compare
ECD_00695 +0.7 1.7 putative inner membrane protein in cydABX-ybgE operon compare
ECD_00660 +0.7 2.0 conserved protein, rhs-like protein compare
ECD_01210 +0.7 1.2 putative patatin-like family phospholipase compare
ECD_t00059 +0.7 1.4 tRNA-Thr compare
ECD_00863 +0.7 2.1 DUF2593 family inner membrane protein compare
ECD_03212 +0.7 1.7 stationary phase-induced protein, putative toxin compare
ECD_02398 +0.6 1.4 nalidixic acid resistance protein, putative periplasmic protein compare
ECD_00920 +0.6 2.6 DUF1006 family protein with C-terminal wHTH domain compare
ECD_04119 +0.6 1.1 SopA-central-domain-like hexapeptide repeat protein compare
ECD_03359 +0.6 2.4 acid-resistance membrane protein compare
ECD_01443 +0.6 2.0 D,D-dipeptide ABC transporter permease compare
ECD_00601 +0.6 4.1 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) compare
ECD_01379 +0.6 1.5 putative DNA-binding transcriptional regulator compare
ECD_02710 +0.6 1.6 CTP:molybdopterin cytidylyltransferase compare
ECD_03407 +0.6 1.9 toxic polypeptide, small compare
ECD_01314 +0.6 2.5 p-aminobenzoyl-glutamate hydrolase, B subunit compare
ECD_02093 +0.6 1.6 putative nucleoside transporter compare
ECD_00230 +0.6 1.5 hypothetical protein compare
ECD_03671 +0.6 1.5 TDP-Fuc4NAc:lipidIIFuc4NAc transferase compare
ECD_02652 +0.6 2.7 hypothetical protein compare
ECD_02126 +0.6 1.9 heme export ABC transporter permease; CcmE-interacting protein compare
ECD_02732 +0.6 1.3 UPF0267 family protein compare
ECD_04062 +0.6 1.2 L-ascorbate-specific enzyme IIA component of PTS compare
ECD_02100 +0.6 1.8 UPF0153 cysteine cluster protein compare
ECD_00439 +0.6 1.7 inner membrane protein; stimulator of the QmcA suppressor of ftsH-htpX compare
ECD_02670 +0.6 2.1 exonuclease V (RecBCD complex), gamma chain compare
ECD_01102 +0.6 2.6 thiamine kinase compare
ECD_02170 +0.6 2.6 transposase_31 family protein compare
ECD_04156 +0.6 3.1 ferric citrate ABC transporter periplasmic binding protein compare
ECD_01481 +0.6 1.9 glutaminase 2 compare
ECD_02713 +0.6 2.0 putative oxidoreductase compare
ECD_03667 +0.6 2.7 glucose-1-phosphate thymidylyltransferase compare
ECD_01620 +0.5 1.6 chromate reductase, quinone reductase, FMN-linked; N-Ethylmaleimide reductase; old yellow enzyme compare
ECD_t00085 +0.5 3.1 tRNA-Leu compare
ECD_01786 +0.5 2.1 putative membrane protein/conserved protein compare
ECD_02300 +0.5 1.9 DUF2502 family putative periplasmic protein compare
ECD_00389 +0.5 2.8 ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease compare
ECD_01045 +0.5 1.1 OPG biosynthetic periplasmic beta-1,6 branching glycosyltransferase compare
ECD_00325 +0.5 2.4 microcin Bac7 uptake protein; outer membrane surface-exposed lipoprotein compare
ECD_01726 +0.5 1.7 molybdopterin synthase sulfurtransferase compare
ECD_00329 +0.5 0.9 anti-RssB factor, RpoS stabilzer during Pi starvation; anti-adapter protein compare
ECD_01174 +0.5 1.2 dihydroxyacetone kinase, C-terminal domain compare
ECD_02834 +0.5 2.0 putative type II secretion protein GspH compare
ECD_00255 +0.5 2.3 50S ribosomal protein L31 type B; alternative zinc-limitation L31 protein compare
ECD_01279 +0.5 1.9 4-aminobutyrate aminotransferase, PLP-dependent compare
ECD_02324 +0.5 2.0 sulfate/thiosulfate ABC transporter permease compare
ECD_01693 +0.5 1.5 uncharacterized protein compare
ECD_01800 +0.5 1.2 putative endopeptidase compare
ECD_00804 +0.5 1.8 soluble aldose sugar dehydrogenase compare
ECD_01854 +0.5 1.9 fused chemotaxis regulator: protein-glutamate methylesterase in two-component regulatory system with CheA compare
ECD_02825 +0.5 0.6 Pyrophosphorylase compare
ECD_01368 +0.5 1.7 putative ATP-dependent helicase compare
ECD_04185 +0.5 1.3 periplasmic chaperone compare
ECD_00629 +0.5 2.6 tRNA-i(6)A37 methylthiotransferase compare
ECD_00704 +0.5 1.3 nicotinamide riboside transporter compare
ECD_03357 +0.5 0.8 acid-resistance protein compare
ECD_02351 +0.5 1.4 RmlC-like cupin domain protein compare
ECD_00322 +0.5 1.1 putative transcriptional regulator compare
ECD_01201 +0.5 1.9 nitrate/nitrite transporter compare
ECD_01452 +0.5 1.0 putative periplasmic M16 family zinc metalloendopeptidase compare
ECD_04123 +0.5 1.0 DUF898 family inner membrane protein compare
ECD_01706 +0.5 1.0 N,N'-diacetylchitobiose-specific enzyme IIC component of PTS compare
ECD_02042 +0.5 1.1 DUF2574 family protein compare
ECD_01032 +0.5 1.3 redox enzyme maturation protein (REMP) chaperone for YcdX compare
ECD_01046 +0.5 1.9 OPG biosynthetic ACP-dependent transmembrane UDP-glucose beta-1,2 glycosyltransferase; nutrient-dependent cell size regulator, FtsZ assembly antagonist compare
ECD_02525 +0.5 1.5 DNA binding protein, nucleoid-associated compare
ECD_00951 +0.5 1.5 6-N-hydroxylaminopurine detoxification oxidoreductase compare
ECD_00257 +0.5 1.6 putative DNA-binding transcriptional regulator compare
ECD_00418 +0.5 1.8 primosomal replication protein N'' compare
ECD_01060 +0.5 1.9 glutaredoxin 2 (Grx2) compare
ECD_01852 +0.5 0.9 chemotaxis regulator, protein phosphatase for CheY compare
ECD_00261 +0.5 1.7 reactive chlorine species (RCS)-specific activator of the rcl genes compare
ECD_01926 +0.5 1.3 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1- (5'-phosphoribosyl)-4-imidazolecarboxamide isomerase compare
ECD_01012 +0.5 1.2 putative reactive intermediate detoxifying aminoacrylate hydrolase compare
ECD_01841 +0.5 1.3 carboxy-SAM synthase compare
ECD_00982 +0.5 1.6 cytochrome bd-II oxidase, subunit II compare
ECD_00779 +0.5 1.1 Fe-binding and storage protein; stress-inducible DNA-binding protein compare
ECD_00228 +0.5 1.9 mRNA interferase toxin of the YafO-YafN toxin-antitoxin system compare
ECD_03270 +0.5 3.8 mal regulon transcriptional activator conserved
ECD_01801 +0.4 3.2 carboxy-terminal protease for penicillin-binding protein 3 compare
ECD_01606 +0.4 1.0 pyridoxamine kinase compare
ECD_02343 +0.4 1.8 ethanolamine transporter compare
ECD_02237 +0.4 3.0 amidophosphoribosyltransferase compare
ECD_02228 +0.4 1.7 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase and dihydroneopterin aldolase compare
ECD_03972 +0.4 2.0 ribophosphonate triphosphate synthase subunit compare
ECD_01982 +0.4 1.4 putative citrate/iron-citrate/zinc-citrate efflux transporter compare
ECD_00667 +0.4 0.9 DUF1722 family protein compare
ECD_03355 +0.4 0.7 Putative LuxR family repressor for dicarboxylate transport compare
ECD_00881 +0.4 1.5 putative OLD family ATP-dependent endonuclease; DUF2813 family protein compare
ECD_02080 +0.4 1.2 galactose- and fucose-inducible galactose regulon transcriptional isorepressor; mgl operon transcriptional repressor; autorepressor compare
ECD_02238 +0.4 0.6 colicin V production protein compare
ECD_04211 +0.4 1.6 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC compare
ECD_03764 +0.4 2.8 putative sulfoquinovose mutarotase compare
ECD_01258 +0.4 1.2 orotidine-5'-phosphate decarboxylase compare
ECD_04178 +0.4 2.2 N-acetylnuraminic acid outer membrane channel protein compare
ECD_02835 +0.4 3.0 putative type II secretion protein GspG compare
ECD_04309 +0.4 1.0 uncharacterized protein compare
ECD_02412 +0.4 3.6 bacterial alpha2-macroglobulin colonization factor ECAM; anti-host protease defense factor; periplasmic inner membrane-anchored lipoprotein compare
ECD_00202 +0.4 2.1 endo/exonuclease/phosphatase family protein compare
ECD_01946 +0.4 0.6 dTDP-L-rhamnose synthase, NAD(P)-dependent dTDP-4-dehydrorhamnose reductase subunit compare
ECD_02435 +0.4 2.0 DoxX family inner membrane protein compare
ECD_00402 +0.4 1.0 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB compare
ECD_01889 +0.4 1.2 cytochrome b561-like protein compare
ECD_03220 +0.4 0.9 small lipoprotein compare
ECD_02671 +0.4 1.4 putative prepilin peptidase-dependent protein compare
ECD_03976 +0.4 1.8 phosphonate ABC transporter periplasmic binding protein compare
ECD_02167 +0.4 1.9 anaerobic sn-glycerol-3-phosphate dehydrogenase, large FAD/NAD(P)-binding subunit compare
ECD_00473 +0.4 2.0 N5-carboxyaminoimidazole ribonucleotide mutase compare
ECD_02853 +0.4 1.4 hypothetical protein compare
ECD_00612 +0.4 1.0 DUF1451 family protein compare
ECD_01649 +0.4 1.1 cysteine desulfurase, stimulated by SufE; selenocysteine lyase, PLP-dependent compare
ECD_03187 +0.4 2.0 bacterioferritin, iron storage and detoxification protein compare
ECD_00293 +0.4 1.9 carbonic anhydrase compare
ECD_01873 +0.4 1.8 ferritin iron storage protein (cytoplasmic) compare
ECD_03021 +0.4 1.1 UPF0306 family protein compare
ECD_04146 +0.4 2.2 IS911 orfA-like protein compare
ECD_01014 +0.4 1.0 ureidoacrylate amidohydrolase compare
ECD_01399 +0.4 0.9 putative ABC transporter permease compare
ECD_04139 +0.4 2.3 uncharacterized protein compare
ECD_02394 +0.4 1.6 exopolyphosphatase compare
ECD_02182 +0.4 2.0 undecaprenyl phosphate-alpha-L-ara4FN deformylase compare
ECD_01264 +0.4 1.1 putative oxidoreductase compare
ECD_02310 +0.4 1.0 DUF3820 family protein compare
ECD_01067 +0.4 1.0 anti-sigma factor for FliA (sigma 28) compare
ECD_00589 +0.4 1.9 sensory histidine kinase in two-component regulatory system with CitB compare
ECD_00744 +0.4 1.6 malonyl-ACP O-methyltransferase, SAM-dependent compare
ECD_01287 +0.4 1.3 putative ABC sugar transporter periplasmic binding protein compare
ECD_00999 +0.4 1.2 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit compare
ECD_01907 +0.4 1.6 hypothetical protein compare
ECD_00570 +0.4 2.6 PAPS reductase-like domain protein compare
ECD_03479 +0.4 1.9 Lipid A-core, surface polymer ligase compare
ECD_03039 +0.4 3.3 putative EptAB family phosphoethanolamine transferase, inner membrane protein compare
ECD_02169 +0.4 1.4 anaerobic sn-glycerol-3-phosphate dehydrogenase, C subunit, 4Fe-4S iron-sulfur cluster compare
ECD_02283 +0.4 1.4 oxalyl CoA decarboxylase, ThDP-dependent compare
ECD_02190 +0.4 1.7 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase compare
ECD_02481 +0.4 1.9 alpha-ketoglutarate transporter compare
ECD_01827 +0.4 1.6 murein DD-endopeptidase, space-maker hydrolase, septation protein compare
ECD_01650 +0.4 1.4 component of SufBCD Fe-S cluster assembly scaffold compare
ECD_00684 +0.4 1.5 succinate dehydrogenase, FeS subunit compare
ECD_02069 +0.4 1.3 tRNA-dihydrouridine synthase C compare
ECD_03906 +0.4 2.6 maltose transporter subunit compare
ECD_02354 +0.4 2.2 malic enzyme: putative oxidoreductase/phosphotransacetylase compare
ECD_01679 +0.4 0.9 glutathione peroxidase compare
ECD_00020 +0.4 1.2 hypothetical protein compare
ECD_02231 +0.4 1.5 histidine ABC transporter ATPase compare
ECD_01238 +0.4 1.7 component I of anthranilate synthase compare
ECD_03433 +0.4 1.3 3-keto-L-gulonate 6-phosphate decarboxylase compare
ECD_01930 +0.4 2.5 UDP-glucose 6-dehydrogenase compare
ECD_03524 +0.4 1.7 transposase compare
ECD_02908 +0.4 2.3 hypothetical protein compare
ECD_00566 +0.4 1.5 DUF466 family protein compare
ECD_00745 +0.4 1.9 dethiobiotin synthetase compare
ECD_03884 +0.4 1.6 GNAT-family putative N-acetyltransferase; acetyl coenzyme A-binding protein compare
ECD_01899 +0.4 1.3 L,D-transpeptidase linking Lpp to murein compare
ECD_01026 +0.4 0.8 biofilm adhesin polysaccharide PGA secretin; OM porin; poly-beta-1,6-N-acetyl-D-glucosamine export protein compare
ECD_00442 +0.4 0.6 iron export ABC transporter permease; peroxide resistance protein compare
ECD_00466 +0.4 1.7 allantoate amidohydrolase compare
ECD_00870 +0.4 0.7 lipoprotein compare
ECD_03943 +0.4 2.4 nitrite reductase, formate-dependent, penta-heme cytochrome c compare
ECD_01459 +0.4 1.2 putative oxidoreductase compare
ECD_02985 +0.4 2.5 tdc operon transcriptional activator compare
ECD_02943 +0.4 1.7 putative tRNA binding protein; putative tRNA corner chaperone compare
ECD_01763 +0.4 0.7 diguanylate cyclase compare
ECD_02058 +0.4 0.9 putative ABC transporter permease compare
ECD_01671 +0.4 1.8 phosphoenolpyruvate synthase compare
ECD_01427 +0.4 1.0 nitrate/nitrite transporter compare
ECD_01349 +0.4 0.9 pyruvate-flavodoxin oxidoreductase compare
ECD_01039 +0.4 0.4 curlin subunit, amyloid curli fibers, cryptic compare
ECD_03096 +0.4 1.2 malate dehydrogenase, NAD(P)-binding compare
ECD_00021 +0.4 0.6 putative usher protein compare
ECD_02833 +0.4 1.3 putative type II secretion protein GspI compare
ECD_02130 +0.3 1.0 nitrate reductase, small, cytochrome C550 subunit, periplasmic compare
ECD_02024 +0.3 1.3 D-tagatose 1,6-bisphosphate aldolase 2, catalytic subunit compare
ECD_04147 +0.3 1.2 hypothetical protein compare
ECD_01785 +0.3 1.2 putative membrane-anchored cyclic-di-GMP phosphodiesterase, regulator of cellulose production compare


Specific Phenotypes

None in this experiment

For Escherichia coli BL21 in phage experiments

For phage MOI 10 across organisms