Experiment set7S165 for Escherichia coli BL21

Compare to:

Bas50

200 most detrimental genes:

  gene name fitness t score description  
ECD_03358 +1.4 2.2 stress response protein acid-resistance protein compare
ECD_01565 +1.4 3.0 putative arabinose efflux transporter compare
ECD_03695 +1.2 1.6 Magnesium and cobalt transport protein corA compare
ECD_01375 +1.2 2.4 putative periplasmic protein compare
ECD_00032 +1.1 1.7 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) compare
ECD_00993 +1.1 1.7 cold shock gene compare
ECD_03357 +1.1 2.0 acid-resistance protein compare
ECD_01107 +1.0 3.1 repressor for bhsA(ycfR) compare
ECD_00442 +1.0 1.3 iron export ABC transporter permease; peroxide resistance protein compare
ECD_01160 +1.0 4.3 oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I compare
ECD_01589 +1.0 1.5 transcriptional repressor of Mal regulon compare
ECD_01459 +0.9 3.0 putative oxidoreductase compare
ECD_02384 +0.9 2.1 putative formate transporter compare
ECD_01482 +0.9 2.0 succinate semialdehyde dehydrogenase, NAD(P)+-dependent compare
ECD_00682 +0.9 2.6 succinate dehydrogenase, membrane subunit, binds cytochrome b556 compare
ECD_02206 +0.9 2.1 NADH:ubiquinone oxidoreductase, chain I compare
ECD_03489 +0.9 5.2 lipopolysaccharide core biosynthesis protein compare
ECD_01044 +0.9 2.0 OPG biosynthetic transmembrane succinyltransferase compare
ECD_01390 +0.9 1.9 IS609 transposase B compare
ECD_00962 +0.9 4.9 SOS cell division inhibitor compare
ECD_01290 +0.9 2.0 putative Zn-dependent NAD(P)-binding oxidoreductase compare
ECD_00582 +0.9 3.5 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase compare
ECD_00807 +0.9 1.0 deoxyribose-5-phosphate-inducible deoxyribose operon transcriptional repressor; repressor of nupG and tsx compare
ECD_02330 +0.9 2.3 penicillin binding protein PBP4B; weak DD-carboxypeptidase activity compare
ECD_02297 +0.8 1.4 putative enzyme IIB component of PTS compare
ECD_01103 +0.8 1.2 beta N-acetyl-glucosaminidase compare
ECD_00904 +0.8 1.6 LysR family putative transcriptional regulator compare
ECD_01623 +0.8 3.1 putative ATP-dependent helicase compare
ECD_02286 +0.8 1.2 putative lipoprotein involved in colanic acid biosynthesis compare
ECD_01599 +0.8 1.4 SoxR iron-sulfur cluster reduction factor component; putative membrane-associated NADH oxidoreductase of electron transport complex compare
ECD_01577 +0.8 1.2 response regulator of RstAB two-component system compare
ECD_00242 +0.8 1.5 moco insertion factor for PaoABC aldehyde oxidoreductase compare
ECD_03486 +0.8 3.4 UDP-glucose:(Glucosyl) LPS alpha1,3-glucosyltransferase WaaO compare
ECD_04194 +0.8 1.3 uncharacterized protein compare
ECD_02278 +0.8 2.1 multidrug resistance efflux pump membrane fusion protein compare
ECD_01928 +0.8 1.8 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase compare
ECD_02048 +0.8 2.3 putative hexameric AAA+ MoxR family ATPase compare
ECD_01559 +0.8 1.6 oxidoreductase, membrane subunit compare
ECD_02841 +0.8 3.2 bifunctional prepilin leader peptidase/ methylase compare
ECD_02333 +0.8 1.6 inner membrane protein compare
ECD_01825 +0.7 2.3 pyruvate kinase II compare
ECD_00684 +0.7 2.6 succinate dehydrogenase, FeS subunit compare
ECD_02035 +0.7 2.9 hypothetical protein compare
ECD_02738 +0.7 1.0 2-octaprenylphenol hydroxylase, FAD-dependent compare
ECD_00708 +0.7 2.7 phosphoglyceromutase 1 compare
ECD_02254 +0.7 2.0 chorismate synthase compare
ECD_02831 +0.7 3.1 putative type II secretion protein GspK compare
ECD_00389 +0.7 3.1 ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease compare
ECD_02774 +0.7 1.3 Zn-dependent metalloprotease-related protein compare
ECD_02838 +0.7 4.6 putative type II secretion protein GspD compare
ECD_04270 +0.7 2.0 non-canonical purine NTP phosphatase, ITPase/XTPase compare
ECD_01650 +0.7 2.1 component of SufBCD Fe-S cluster assembly scaffold compare
ECD_02456 +0.7 1.4 putative 4Fe-4S cluster-containing protein compare
ECD_01405 +0.7 1.6 methionine N-acyltransferase; L-amino acid N-acyltransferase compare
ECD_01056 +0.7 1.4 biofilm regulator compare
ECD_00455 +0.7 1.9 ureidoglycolate lyase, releasing urea compare
ECD_02416 +0.6 2.1 Fe(2+) donor and activity modulator for cysteine desulfurase compare
ECD_04212 +0.6 1.7 5-methylcytosine-specific restriction enzyme McrBC, subunit McrB compare
ECD_03733 +0.6 3.9 transcription antitermination protein compare
ECD_01619 +0.6 2.6 transcriptional repressor for the nemRA-gloA operon, quinone-, glyoxal-, and HOCl-activated compare
ECD_01013 +0.6 2.2 putative aminoacrylate deaminase, reactive intermediate detoxification; weak enamine/imine deaminase activity compare
ECD_00704 +0.6 1.3 nicotinamide riboside transporter compare
ECD_01575 +0.6 1.2 dihydromonapterin reductase, NADPH-dependent; dihydrofolate reductase isozyme compare
ECD_02839 +0.6 3.4 putative secretion pathway protein, C-type protein compare
ECD_01064 +0.6 1.0 putative oxidoreductase compare
ECD_01374 +0.6 2.5 cytochrome b561 compare
ECD_02842 +0.6 5.5 putative secreted and surface-associated lipoprotein mucinase compare
ECD_00188 +0.6 1.4 UPF0253 family protein compare
ECD_02849 +0.6 2.6 glycolate-inducible glc operon transcriptional repressor; autorepressor compare
ECD_02537 +0.6 4.8 putative L-valine exporter, norvaline resistance protein compare
ECD_03469 +0.6 2.4 putative rhodanese-related sulfurtransferase compare
ECD_04145 +0.6 1.4 IS911 protein compare
ECD_01630 +0.6 1.2 LysR family putative transcriptional regulator compare
ECD_01912 +0.6 1.6 DNA gyrase inhibitor compare
ECD_01175 +0.6 2.4 dihydroxyacetone kinase, PTS-dependent, dihydroxyacetone-binding subunit compare
ECD_01046 +0.6 2.7 OPG biosynthetic ACP-dependent transmembrane UDP-glucose beta-1,2 glycosyltransferase; nutrient-dependent cell size regulator, FtsZ assembly antagonist compare
ECD_00556 +0.6 1.5 iron-enterobactin ABC transporter permease compare
ECD_00758 +0.6 1.5 inner membrane protein compare
ECD_03022 +0.6 0.8 GIY-YIG nuclease superfamily protein compare
ECD_02835 +0.6 3.8 putative type II secretion protein GspG compare
ECD_01026 +0.6 1.4 biofilm adhesin polysaccharide PGA secretin; OM porin; poly-beta-1,6-N-acetyl-D-glucosamine export protein compare
ECD_00843 +0.5 1.7 phage baseplate assembly protein compare
ECD_00252 +0.5 2.3 ECP pilin compare
ECD_01058 +0.5 1.1 dihydro-orotase compare
ECD_02528 +0.5 2.4 putative membrane-anchored DUF883 family ribosome-binding protein compare
ECD_00763 +0.5 1.6 DUF1956 domain-containing tetR family putative transcriptional regulator compare
ECD_02033 +0.5 1.1 hypothetical protein compare
ECD_01245 +0.5 1.7 23S rRNA pseudouridine(2605) synthase compare
ECD_01886 +0.5 1.1 membrane-anchored, periplasmic TMAO, DMSO reductase compare
ECD_01694 +0.5 1.1 fructosamine kinase family protein compare
ECD_01571 +0.5 1.2 pyridine nucleotide transhydrogenase, beta subunit compare
ECD_00949 +0.5 1.1 dihydro-orotate oxidase, FMN-linked compare
ECD_00757 +0.5 2.5 endo/exonuclease/phosphatase family protein compare
ECD_01225 +0.5 0.8 putative DGPF domain-containing enzyme compare
ECD_02304 +0.5 1.4 DUF1323 family putative DNA-binding protein compare
ECD_04339 +0.5 1.6 stress-induced small enterobacterial protein compare
ECD_00674 +0.5 2.2 endonuclease VIII and 5-formyluracil/5-hydroxymethyluracil DNA glycosylase compare
ECD_02718 +0.5 1.1 putative 4Fe-4S ferredoxin-type oxidoreductase subunit compare
ECD_00388 +0.5 2.1 proteolytic subunit of ClpA-ClpP and ClpX-ClpP ATP-dependent serine proteases compare
ECD_01031 +0.5 1.9 alkaline phosphatase compare
ECD_01773 +0.5 1.0 putative YeaWX dioxygenase beta subunit, reductase component compare
ECD_03645 +0.5 1.0 ilvG operon leader peptide compare
ECD_01403 +0.5 1.2 DUF2526 family protein compare
ECD_01321 +0.5 1.2 tRNA s(2)C32 thioltransferase, iron sulfur cluster protein compare
ECD_02284 +0.5 1.2 formyl-CoA transferase, NAD(P)-binding compare
ECD_01220 +0.5 2.3 oligopeptide ABC transporter ATPase compare
ECD_01824 +0.5 3.0 putative DNA-binding transcriptional regulator compare
ECD_01535 +0.5 1.2 hypothetical protein compare
ECD_02836 +0.5 2.7 putative type II secretion protein GspF compare
ECD_03276 +0.5 2.5 thiosulfate:cyanide sulfurtransferase (rhodanese) compare
ECD_00948 +0.5 1.4 putative periplasmic pilin chaperone compare
ECD_02285 +0.5 0.9 uncharacterized protein compare
ECD_00811 +0.5 1.5 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase; pyrimidine phosphatase; riboflavin synthesis compare
ECD_01153 +0.5 1.1 periplasmic inhibitor of g-type lysozyme compare
ECD_01606 +0.5 1.4 pyridoxamine kinase compare
ECD_00830 +0.5 1.4 hypothetical protein compare
ECD_03746 +0.5 2.0 periplasmic protein disulfide isomerase I compare
ECD_02138 +0.5 2.7 microcin J25 efflux ABC transporter permease/ATPase compare
ECD_00464 +0.5 1.2 glycerate kinase II compare
ECD_03180 +0.5 1.0 putative general secretory pathway component, cryptic compare
ECD_02543 +0.5 4.3 glutamate-cysteine ligase compare
ECD_02056 +0.5 1.3 transcriptional activator of csgD and csgBA compare
ECD_01401 +0.5 1.1 gamma-aminobutyraldehyde dehydrogenase compare
ECD_04150 +0.5 2.0 IS600 ORF1-like protein compare
ECD_02038 +0.5 0.8 hypothetical protein compare
ECD_01472 +0.5 1.1 autoinducer 2 import system permease protein compare
ECD_03696 +0.5 0.7 DUF2628 family putative inner membrane protein compare
ECD_03998 +0.5 1.1 GNAT family putative N-acetyltransferase compare
ECD_02168 +0.5 1.5 anaerobic sn-glycerol-3-phosphate dehydrogenase membrane anchor subunit compare
ECD_03072 +0.5 2.3 Mg(2+)-starvation-stimulated protein compare
ECD_01069 +0.5 1.1 flagellar component of cell-proximal portion of basal-body rod compare
ECD_02837 +0.5 2.7 putative type II secretion protein GspE compare
ECD_00795 +0.5 1.5 Isoaspartyl peptidase compare
ECD_02834 +0.5 1.6 putative type II secretion protein GspH compare
ECD_01899 +0.5 1.2 L,D-transpeptidase linking Lpp to murein compare
ECD_00612 +0.5 0.9 DUF1451 family protein compare
ECD_04172 +0.5 1.5 putative methyltransferase compare
ECD_01879 +0.5 0.7 response regulator in two-component regulatory system with BarA compare
ECD_00336 +0.5 2.3 OxyR-regulated conserved protein compare
ECD_02768 +0.5 3.4 biosynthetic arginine decarboxylase, PLP-binding compare
ECD_04040 +0.5 2.3 GTPase, stimulated by 50S subunit binding; Mn(2+) homeostasis regulator compare
ECD_02477 +0.5 1.1 DTW domain protein compare
ECD_00407 +0.5 0.7 DUF1428 family protein compare
ECD_00309 +0.5 2.8 S-formylglutathione hydrolase compare
ECD_03962 +0.5 1.9 ribose 5-phosphate isomerase B/allose 6-phosphate isomerase compare
ECD_02090 +0.5 1.0 nucleoside permease compare
ECD_02541 +0.5 3.3 multidrug efflux system protein compare
ECD_00976 +0.5 1.9 hydrogenase 1, large subunit compare
ECD_00251 +0.5 1.7 ECP production pilus chaperone compare
ECD_02445 +0.4 1.1 regulatory protein P-II for glutamine synthetase compare
ECD_03453 +0.4 1.0 DUF3302 family inner membrane protein compare
ECD_03997 +0.4 1.1 putative 4Fe-4S mono-cluster protein compare
ECD_02052 +0.4 1.4 lipoprotein, DUF1307 family compare
ECD_02525 +0.4 0.8 DNA binding protein, nucleoid-associated compare
ECD_02272 +0.4 2.3 ABC transporter maintaining OM lipid asymmetry, OM lipoprotein component compare
ECD_01124 +0.4 0.9 spermidine/putrescine ABC transporter ATPase compare
ECD_00438 +0.4 0.7 copper-responsive regulon transcriptional regulator compare
ECD_03009 +0.4 1.7 putative fimbrial-like adhesin protein compare
ECD_01814 +0.4 1.1 C-N hydrolase family protein compare
ECD_03541 +0.4 1.0 hypothetical protein compare
ECD_03103 +0.4 2.2 transcriptional regulator for aaeXAB operon compare
ECD_02116 +0.4 1.9 spermidine nucleoid-associated protein compare
ECD_01894 +0.4 1.2 AMP nucleosidase compare
ECD_01264 +0.4 1.0 putative oxidoreductase compare
ECD_03456 +0.4 1.4 mannitol operon repressor compare
ECD_01077 +0.4 2.8 flagellar rod assembly protein and murein hydrolase; flagellum-specific muramidase compare
ECD_00844 +0.4 1.4 putative phage tail protein compare
ECD_02869 +0.4 0.9 maturation protease for hydrogenase 2 compare
ECD_00261 +0.4 1.5 reactive chlorine species (RCS)-specific activator of the rcl genes compare
ECD_02075 +0.4 1.1 dihydropyrimidine dehydrogenase, NADH-dependent, subunit N compare
ECD_03349 +0.4 2.4 glutathione oxidoreductase compare
ECD_02430 +0.4 2.6 3-phenylpropionate dioxygenase, large (alpha) subunit compare
ECD_01166 +0.4 1.3 putative cation/proton antiporter compare
ECD_02539 +0.4 2.4 transcriptional repressor of microcin B17 synthesis and multidrug efflux compare
ECD_01601 +0.4 0.6 SoxR iron-sulfur cluster reduction factor component; putative membrane protein of electron transport complex compare
ECD_03057 +0.4 2.5 ABC transporter maintaining OM lipid asymmetry, periplasmic binding protein compare
ECD_00262 +0.4 1.9 cysteine-rich LutA family protein; putative electron transport chain YkgEFG component compare
ECD_04379 +0.4 1.2 hypothetical protein compare
ECD_02946 +0.4 1.1 evolved beta-D-galactosidase, beta subunit; cupin superfamily compare
ECD_00771 +0.4 1.5 Fe(II)-dependent oxygenase superfamily protein compare
ECD_03766 +0.4 1.6 6-deoxy-6-sulfofructose-1-phosphate aldolase compare
ECD_00466 +0.4 1.6 allantoate amidohydrolase compare
ECD_02354 +0.4 2.2 malic enzyme: putative oxidoreductase/phosphotransacetylase compare
ECD_00406 +0.4 1.3 excision repair protein, alkyltransferase-like protein ATL compare
ECD_00551 +0.4 1.8 enterobactin/ferrienterobactin esterase compare
ECD_02858 +0.4 1.8 hypothetical protein compare
ECD_00898 +0.4 1.2 dimethyl sulfoxide reductase, anaerobic, subunit A compare
ECD_00748 +0.4 1.0 molybdopterin biosynthesis protein A compare
ECD_04093 +0.4 1.2 GGCT-like protein compare
ECD_02415 +0.4 1.4 aminopeptidase B compare
ECD_01014 +0.4 0.8 ureidoacrylate amidohydrolase compare
ECD_00067 +0.4 1.4 DedA family inner membrane protein compare
ECD_02065 +0.4 1.2 Yip1 family inner membrane protein compare
ECD_01082 +0.4 1.9 23S rRNA pseudouridine(955,2504,2580) synthase compare
ECD_01032 +0.4 0.6 redox enzyme maturation protein (REMP) chaperone for YcdX compare
ECD_01365 +0.4 0.7 putative esterase compare
ECD_00257 +0.4 1.1 putative DNA-binding transcriptional regulator compare
ECD_04108 +0.4 2.8 trehalose-specific PTS enzyme: IIB and IIC component compare
ECD_03064 +0.4 0.9 periplasmic membrane-anchored LPS-binding protein; LPS export protein compare
ECD_01247 +0.4 1.0 putative EmrKY-TolC system oxoacyl-(acyl carrier protein) reductase compare


Specific Phenotypes

None in this experiment

For Escherichia coli BL21 in phage experiments

For phage MOI 10 across organisms