Experiment set7S106 for Escherichia coli BL21

Compare to:

Bas32

200 most detrimental genes:

  gene name fitness t score description  
ECD_00930 +1.3 3.7 M15A protease-related family periplasmic protein compare
ECD_01230 +1.1 2.1 outer membrane protein W compare
ECD_03308 +1.0 1.5 PanD autocleavage accelerator, panothenate synthesis compare
ECD_01694 +1.0 2.2 fructosamine kinase family protein compare
ECD_01044 +1.0 2.4 OPG biosynthetic transmembrane succinyltransferase compare
ECD_01225 +1.0 2.3 putative DGPF domain-containing enzyme compare
ECD_01591 +1.0 2.3 PLP-dependent beta-cystathionase and maltose regulon regulator compare
ECD_02162 +1.0 1.8 ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance compare
ECD_02404 +0.9 1.6 BamABCDE complex OM biogenesis lipoprotein compare
ECD_01599 +0.9 1.3 SoxR iron-sulfur cluster reduction factor component; putative membrane-associated NADH oxidoreductase of electron transport complex compare
ECD_01879 +0.9 1.6 response regulator in two-component regulatory system with BarA compare
ECD_00296 +0.9 2.4 thiogalactoside acetyltransferase compare
ECD_00032 +0.9 1.8 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) compare
ECD_01107 +0.9 2.9 repressor for bhsA(ycfR) compare
ECD_00487 +0.9 1.5 Excisionase compare
ECD_01577 +0.8 1.8 response regulator of RstAB two-component system compare
ECD_01014 +0.8 2.6 ureidoacrylate amidohydrolase compare
ECD_00322 +0.8 1.4 putative transcriptional regulator compare
ECD_03695 +0.8 1.1 Magnesium and cobalt transport protein corA compare
ECD_04119 +0.8 1.3 SopA-central-domain-like hexapeptide repeat protein compare
ECD_01851 +0.8 1.7 flagellin export apparatus, substrate specificity protein compare
ECD_04392 +0.8 2.5 uncharacterized protein compare
ECD_02694 +0.7 0.9 putative LuxR family transcriptional regulator compare
ECD_00849 +0.7 1.6 putative DNA-invertase compare
ECD_02033 +0.7 1.5 hypothetical protein compare
ECD_00209 +0.7 1.9 lipoprotein compare
ECD_03727 +0.7 1.5 aerobic ubiquinone synthesis protein, SCP2 family protein compare
ECD_02065 +0.7 2.3 Yip1 family inner membrane protein compare
ECD_02330 +0.7 2.4 penicillin binding protein PBP4B; weak DD-carboxypeptidase activity compare
ECD_03180 +0.7 2.1 putative general secretory pathway component, cryptic compare
ECD_01400 +0.7 1.7 putative ABC transporter permease compare
ECD_04139 +0.7 3.8 uncharacterized protein compare
ECD_02238 +0.7 1.2 colicin V production protein compare
ECD_03998 +0.7 1.8 GNAT family putative N-acetyltransferase compare
ECD_02345 +0.7 1.4 ethanolamine utilization protein, HSP70/actin superfamily protein compare
ECD_04048 +0.7 1.6 DUF2170 family protein compare
ECD_00500 +0.7 1.7 DLP12 prophage; endonuclease RUS compare
ECD_03522 +0.7 3.0 Single-strand binding protein (SSB) (Helix-destabilizing protein) compare
ECD_02189 +0.7 2.0 dihydroxynaphthoic acid synthetase compare
ECD_02299 +0.7 3.1 putative ion channel protein compare
ECD_02042 +0.7 1.6 DUF2574 family protein compare
ECD_02044 +0.7 1.3 methionyl-tRNA synthetase compare
ECD_03122 +0.7 2.4 acrAB operon transcriptional repressor compare
ECD_01565 +0.7 1.4 putative arabinose efflux transporter compare
ECD_01977 +0.6 1.4 ser/thr phosphatase-related protein compare
ECD_00269 +0.6 2.8 choline-inducible betIBA-betT divergent operon transcriptional repressor compare
ECD_01918 +0.6 2.4 LysR family putative transcriptional regulator compare
ECD_01365 +0.6 1.5 putative esterase compare
ECD_00682 +0.6 1.2 succinate dehydrogenase, membrane subunit, binds cytochrome b556 compare
ECD_00593 +0.6 2.5 constitutive cold shock family transcription antitermination protein; negative regulator of cspA transcription; RNA melting protein; ssDNA-binding protein compare
ECD_02192 +0.6 1.4 isochorismate synthase 2 compare
ECD_02054 +0.6 1.4 putative response regulator in two-component system withYehU compare
ECD_03121 +0.6 0.9 putative membrane protein compare
ECD_01773 +0.6 1.3 putative YeaWX dioxygenase beta subunit, reductase component compare
ECD_00950 +0.6 1.2 FtsZ stabilizer compare
ECD_02035 +0.6 2.2 hypothetical protein compare
ECD_00582 +0.6 1.6 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase compare
ECD_01655 +0.6 1.3 1,4-dihydroxy-2-naphthoyl-CoA hydrolase compare
ECD_01277 +0.6 1.2 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; succinate semialdehyde dehydrogenase compare
ECD_03022 +0.6 2.2 GIY-YIG nuclease superfamily protein compare
ECD_02182 +0.6 1.8 undecaprenyl phosphate-alpha-L-ara4FN deformylase compare
ECD_01721 +0.5 0.9 TVP38/TMEM64 family inner membrane protein compare
ECD_01675 +0.5 1.9 UPF0061 family protein compare
ECD_00569 +0.5 1.6 Spo0J family protein, ParB-like nuclease domain compare
ECD_02258 +0.5 1.3 putative fimbrial-like adhesin protein compare
ECD_00660 +0.5 1.9 conserved protein, rhs-like protein compare
ECD_01774 +0.5 1.3 ribonuclease D compare
ECD_01719 +0.5 1.0 TVP38/TMEM64 family inner membrane protein compare
ECD_01693 +0.5 0.6 uncharacterized protein compare
ECD_00795 +0.5 2.0 Isoaspartyl peptidase compare
ECD_01375 +0.5 1.0 putative periplasmic protein compare
ECD_03867 +0.5 1.9 thiamine biosynthesis ThiGH complex subunit compare
ECD_01651 +0.5 1.7 SufBCD Fe-S cluster assembly scaffold protein, ATP-binding protein compare
ECD_02327 +0.5 2.3 repressor for murPQ, MurNAc 6-P inducible compare
ECD_04122 +0.5 2.3 GNAT family putative N-acetyltransferase compare
ECD_01273 +0.5 0.8 putrescine importer compare
ECD_01290 +0.5 0.9 putative Zn-dependent NAD(P)-binding oxidoreductase compare
ECD_00835 +0.5 0.9 hypothetical protein compare
ECD_02475 +0.5 2.1 putative methyltransferase compare
ECD_01861 +0.5 1.8 proton conductor component of flagella motor compare
ECD_00339 +0.5 1.7 hypothetical protein compare
ECD_01799 +0.5 1.6 putative transporter compare
ECD_03023 +0.5 1.7 GNAT family putative N-acetyltransferase compare
ECD_01825 +0.5 1.7 pyruvate kinase II compare
ECD_00612 +0.5 0.8 DUF1451 family protein compare
ECD_02815 +0.5 2.7 Capsule polysaccharide export inner-membrane protein kpsE compare
ECD_02899 +0.5 0.8 inner membrane protein compare
ECD_02405 +0.5 1.2 ancillary SecYEG translocon subunit; putative anti-RcsB factor compare
ECD_04362 +0.5 0.9 hypothetical protein compare
ECD_00300 +0.5 2.5 mhp operon transcriptional activator compare
ECD_02075 +0.5 1.4 dihydropyrimidine dehydrogenase, NADH-dependent, subunit N compare
ECD_00791 +0.5 1.3 putative pyruvate formate lyase activating enzyme compare
ECD_01953 +0.4 1.6 colanic biosynthesis UDP-glucose lipid carrier transferase compare
ECD_01390 +0.4 1.3 IS609 transposase B compare
ECD_01828 +0.4 1.0 zinc ABC transporter periplasmic binding protein compare
ECD_01060 +0.4 2.1 glutaredoxin 2 (Grx2) compare
ECD_02833 +0.4 1.2 putative type II secretion protein GspI compare
ECD_02384 +0.4 0.8 putative formate transporter compare
ECD_03481 +0.4 1.6 UDP-galactose:(Galactosyl) LPS alpha1,2-galactosyltransferase compare
ECD_01854 +0.4 1.0 fused chemotaxis regulator: protein-glutamate methylesterase in two-component regulatory system with CheA compare
ECD_00951 +0.4 1.7 6-N-hydroxylaminopurine detoxification oxidoreductase compare
ECD_01619 +0.4 1.8 transcriptional repressor for the nemRA-gloA operon, quinone-, glyoxal-, and HOCl-activated compare
ECD_01210 +0.4 0.8 putative patatin-like family phospholipase compare
ECD_01671 +0.4 1.7 phosphoenolpyruvate synthase compare
ECD_03696 +0.4 0.7 DUF2628 family putative inner membrane protein compare
ECD_00464 +0.4 1.3 glycerate kinase II compare
ECD_02428 +0.4 2.0 putative 3-phenylpropionic transporter compare
ECD_04242 +0.4 2.3 putative transcriptional regulator compare
ECD_03131 +0.4 1.0 DUF1488 family protein compare
ECD_02914 +0.4 1.9 BMFP family putative fusogenic protein compare
ECD_02091 +0.4 1.1 ribonucleoside hydrolase 2 compare
ECD_00931 +0.4 1.8 putative metal-binding enzyme compare
ECD_01058 +0.4 1.0 dihydro-orotase compare
ECD_01844 +0.4 0.9 TMAO reductase III (TorYZ), cytochrome c-type subunit compare
ECD_03081 +0.4 2.0 DUF386 family protein, cupin superfamily compare
ECD_00327 +0.4 1.6 DUF2754 family putative inner membrane protein compare
ECD_03576 +0.4 1.7 2-oxo-3-deoxygalactonate 6-phosphate aldolase compare
ECD_01221 +0.4 1.1 oligopeptide ABC transporter ATPase compare
ECD_02862 +0.4 1.7 putative ATP-binding protein compare
ECD_00405 +0.4 0.7 outer membrane lipoprotein compare
ECD_00977 +0.4 1.9 hydrogenase 1, b-type cytochrome subunit compare
ECD_03230 +0.4 1.7 DUF2620 family protein compare
ECD_01040 +0.4 0.7 curli assembly protein compare
ECD_01786 +0.4 0.9 putative membrane protein/conserved protein compare
ECD_00192 +0.4 1.9 putative lipoprotein compare
ECD_01634 +0.4 1.1 multidrug efflux system transporter compare
ECD_01857 +0.4 1.1 methyl-accepting chemotaxis protein II compare
ECD_00013 +0.4 1.5 UPF0412 family protein compare
ECD_01435 +0.4 0.8 putative DNA-binding transcriptional regulator compare
ECD_01488 +0.4 0.9 putative phage protein compare
ECD_00807 +0.4 0.5 deoxyribose-5-phosphate-inducible deoxyribose operon transcriptional repressor; repressor of nupG and tsx compare
ECD_02392 +0.4 1.9 phosphoribosylglycinamide formyltransferase 1 compare
ECD_01782 +0.4 0.8 aminodeoxychorismate synthase, subunit I compare
ECD_00749 +0.4 1.2 inactive molybdopterin adenylyltransferase compare
ECD_00828 +0.4 1.2 hypothetical protein compare
ECD_01031 +0.4 0.8 alkaline phosphatase compare
ECD_00440 +0.4 2.0 PHB domain membrane-anchored putative protease compare
ECD_01979 +0.4 1.1 multidrug efflux system, subunit A compare
ECD_03013 +0.4 1.6 16S rRNA C1402 2'-O-ribose methyltransferase, SAM-dependent compare
ECD_02915 +0.4 1.0 putative fimbrial-like adhesin protein compare
ECD_03541 +0.4 0.9 hypothetical protein compare
ECD_03415 +0.4 1.1 YiaAB family inner membrane protein compare
ECD_03917 +0.4 1.8 stress-induced protein, UPF0337 family compare
ECD_00955 +0.4 1.0 paraquat-inducible, SoxRS-regulated MCE domain protein compare
ECD_00658 +0.4 1.4 Rhs protein with putative toxin domain; putative neighboring cell growth inhibitor compare
ECD_00005 +0.4 1.5 DUF2502 family putative periplasmic protein compare
ECD_00976 +0.4 1.5 hydrogenase 1, large subunit compare
ECD_00655 +0.4 1.3 potassium translocating ATPase, subunit A compare
ECD_00194 +0.4 1.4 tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase, SAM-dependent compare
ECD_00940 +0.4 0.7 aliphatic sulfonate ABC transporter periplasmic binding protein compare
ECD_02524 +0.4 1.4 DUF2892 family inner membrane rhodanese compare
ECD_02391 +0.4 1.3 phosphoribosylaminoimidazole synthetase compare
ECD_00394 +0.4 1.5 putative competence-suppressing periplasmic helix-hairpin-helix DNA-binding protein compare
ECD_00683 +0.4 1.6 succinate dehydrogenase, flavoprotein subunit compare
ECD_01681 +0.4 0.4 integration host factor (IHF), DNA-binding protein, alpha subunit compare
ECD_00898 +0.4 1.6 dimethyl sulfoxide reductase, anaerobic, subunit A compare
ECD_01320 +0.4 1.1 ATP-dependent RNA helicase, specific for 23S rRNA compare
ECD_02985 +0.4 1.9 tdc operon transcriptional activator compare
ECD_04063 +0.4 1.4 3-keto-L-gulonate 6-phosphate decarboxylase compare
ECD_04117 +0.4 1.9 transcriptional repressor for divergent bdcA compare
ECD_02760 +0.4 1.2 MtlR family putative transcriptional repressor compare
ECD_02176 +0.4 1.2 outer membrane protein, putative porin compare
ECD_03059 +0.3 1.8 ABC transporter maintaining OM lipid asymmetry, inner membrane permease protein compare
ECD_04135 +0.3 1.8 broad specificity NADPH-dependent aldehyde reductase, Zn-containing compare
ECD_01969 +0.3 1.1 inner membrane protein compare
ECD_04142 +0.3 0.9 GFO/IDH/MOCA family putative oxidoreductase NAD(P)-dependent compare
ECD_01279 +0.3 0.9 4-aminobutyrate aminotransferase, PLP-dependent compare
ECD_02609 +0.3 2.0 sulfite reductase, alpha subunit, flavoprotein compare
ECD_01313 +0.3 0.7 p-aminobenzoyl-glutamate transporter; membrane protein compare
ECD_00956 +0.3 0.7 DUF330 family putative lipoprotein compare
ECD_02114 +0.3 1.5 putative ATP-dependent DNA or RNA helicase compare
ECD_02059 +0.3 1.3 putative ABC transporter ATPase compare
ECD_00676 +0.3 1.6 putative fimbrial protein compare
ECD_02304 +0.3 1.4 DUF1323 family putative DNA-binding protein compare
ECD_01980 +0.3 1.3 multidrug efflux system, subunit B compare
ECD_01575 +0.3 0.8 dihydromonapterin reductase, NADPH-dependent; dihydrofolate reductase isozyme compare
ECD_02373 +0.3 0.7 hydrogenase 4, 4Fe-4S subunit compare
ECD_04056 +0.3 1.3 bioflm peroxide resistance protein compare
ECD_03557 +0.3 2.1 multidrug efflux system protein compare
ECD_03359 +0.3 1.3 acid-resistance membrane protein compare
ECD_00893 +0.3 1.6 leucine-responsive global transcriptional regulator compare
ECD_00881 +0.3 1.1 putative OLD family ATP-dependent endonuclease; DUF2813 family protein compare
ECD_02927 +0.3 1.4 undecaprenyl pyrophosphate phosphatase compare
ECD_04226 +0.3 1.5 2-oxo-hept-3-ene-1,7-dioate hydratase compare
ECD_00335 +0.3 1.1 shikimate kinase II compare
ECD_01749 +0.3 0.3 D-hexose-6-phosphate epimerase-like protein compare
ECD_01007 +0.3 0.8 NAD(P)H:quinone oxidoreductase compare
ECD_00909 +0.3 1.6 ribosomal protein S12 methylthiotransferase accessory factor compare
ECD_02351 +0.3 0.5 RmlC-like cupin domain protein compare
ECD_02698 +0.3 2.6 LysM domain-containing M23 family putative peptidase; septation lipoprotein compare
ECD_03245 +0.3 1.2 DNA catabolic protein compare
ECD_03298 +0.3 1.7 glycerophosphodiester phosphodiesterase, cytosolic compare
ECD_02354 +0.3 1.8 malic enzyme: putative oxidoreductase/phosphotransacetylase compare
ECD_01572 +0.3 0.8 pyridine nucleotide transhydrogenase, alpha subunit compare
ECD_00591 +0.3 1.4 anaerobic C4-dicarboxylate transport compare
ECD_04173 +0.3 1.9 GNAT family putative N-acetyltransferase compare
ECD_01478 +0.3 0.8 altronate oxidoreductase, NAD-dependent compare
ECD_03403 +0.3 1.9 glyoxylate/hydroxypyruvate reductase B compare
ECD_00961 +0.3 2.1 outer membrane protein A (3a compare
ECD_02334 +0.3 0.9 GNAT family putative N-acetyltransferase compare


Specific Phenotypes

None in this experiment

For Escherichia coli BL21 in phage experiments

For phage MOI 10 across organisms