Experiment set7IT080 for Escherichia coli BW25113

Compare to:

Dodecanol and Rhamnolipid carbon source

200 most important genes:

  gene name fitness t score description  
b1830 prc -6.6 -4.6 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b4242 mgtA -6.0 -17.2 magnesium transporter (NCBI) compare
b0222 lpcA -5.9 -4.1 phosphoheptose isomerase (NCBI) compare
b1129 phoQ -5.9 -9.9 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b1130 phoP -5.9 -9.6 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b0957 ompA -5.5 -4.6 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3026 qseC -5.3 -6.3 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0145 dksA -5.0 -3.4 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2114 metG -4.9 -1.8 methionyl-tRNA synthetase (NCBI) compare
b0463 acrA -4.9 -10.9 multidrug efflux system (NCBI) compare
b1192 ldcA -4.7 -6.2 L,D-carboxypeptidase A (NCBI) compare
b3630 rfaP -4.6 -19.8 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3631 rfaG -4.6 -23.3 glucosyltransferase I (NCBI) compare
b0053 surA -4.5 -3.1 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3621 rfaC -4.5 -9.6 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3035 tolC -4.5 -11.9 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3741 gidA -4.5 -8.6 glucose-inhibited division protein A (NCBI) compare
b3620 rfaF -4.5 -9.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3229 sspA -4.4 -6.7 stringent starvation protein A (NCBI) compare
b0088 murD -4.3 -2.9 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b1236 galU -4.3 -9.1 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0200 gmhB -4.2 -2.9 hypothetical protein (NCBI) compare
b3619 rfaD -4.2 -6.9 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3842 rfaH -4.2 -8.8 transcriptional activator RfaH (NCBI) compare
b0740 tolB -4.0 -7.9 translocation protein TolB precursor (NCBI) compare
b0462 acrB -4.0 -15.1 multidrug efflux system protein (NCBI) compare
b0051 ksgA -3.7 -9.6 dimethyladenosine transferase (NCBI) compare
b3706 trmE -3.7 -9.5 tRNA modification GTPase (NCBI) compare
b3863 polA -3.6 -2.3 DNA polymerase I (NCBI) compare
b0232 yafN -3.6 -1.3 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3725 pstB -3.6 -2.4 phosphate transporter subunit (NCBI) compare
b3261 fis -3.5 -6.2 DNA-binding protein Fis (NCBI) compare
b1677 lpp -3.4 -2.2 murein lipoprotein (NCBI) compare
b3405 ompR -3.4 -7.0 osmolarity response regulator (NCBI) compare
b4481 rffT -3.4 -8.0 4-alpha-L-fucosyltransferase (NCBI) compare
b0720 gltA -3.4 -5.7 citrate synthase (NCBI) compare
b0737 tolQ -3.3 -5.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2528 iscA -3.3 -2.4 iron-sulfur cluster assembly protein (NCBI) compare
b3839 tatC -3.3 -8.4 TatABCE protein translocation system subunit (NCBI) compare
b0738 tolR -3.3 -5.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4702 mgtL -3.2 -3.2 regulatory leader peptide for mgtA (NCBI) compare
b2512 yfgL -3.2 -5.0 protein assembly complex, lipoprotein component (NCBI) compare
b0739 tolA -3.2 -7.2 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3052 rfaE -3.1 -6.2 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3463 ftsE -2.9 -6.3 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b4171 miaA -2.9 -5.2 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b3462 ftsX -2.8 -7.1 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2051 wcaH -2.7 -2.0 GDP-mannose mannosyl hydrolase (VIMSS) compare
b4451 ryhB -2.7 -1.4 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b2281 nuoI -2.7 -3.6 NADH dehydrogenase subunit I (NCBI) compare
b3163 nlpI -2.6 -4.6 hypothetical protein (NCBI) compare
b0726 sucA -2.6 -4.9 alpha-ketoglutarate decarboxylase (NCBI) compare
b3236 mdh -2.5 -6.7 malate dehydrogenase (NCBI) compare
b4676 yoaK -2.4 -1.7 expressed protein (RefSeq) compare
b3728 pstS -2.4 -5.6 phosphate transporter subunit (NCBI) compare
b3613 yibP -2.3 -6.1 putative membrane protein (VIMSS) compare
b0741 pal -2.2 -3.8 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0142 folK -2.2 -1.0 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b0688 pgm -2.1 -4.4 phosphoglucomutase (NCBI) compare
b3632 rfaQ -2.1 -13.6 lipopolysaccharide core biosynthesis protein (NCBI) compare
b2567 rnc -2.1 -1.9 ribonuclease III (NCBI) compare
b3194 yrbE -2.1 -7.4 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3500 gor -2.0 -2.1 glutathione reductase (NCBI) compare
b2276 nuoN -2.0 -4.5 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b2215 ompC -2.0 -6.4 outer membrane porin protein C (NCBI) compare
b3627 rfaI -1.9 -9.4 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b4577 sgrS -1.9 -1.9 small antisense RNA (NCBI) compare
b4695 ykgT -1.9 -1.8 no description compare
b1860 ruvB -1.8 -2.3 Holliday junction DNA helicase B (NCBI) compare
b3164 pnp -1.8 -3.0 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1150 ymfR -1.8 -1.1 e14 prophage; predicted protein (NCBI) compare
b3628 rfaB -1.8 -9.3 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b3784 rfe -1.8 -8.9 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b2953 yggU -1.7 -2.1 orf, hypothetical protein (VIMSS) compare
b4172 hfq -1.7 -1.8 RNA-binding protein Hfq (NCBI) compare
b0118 acnB -1.7 -3.5 aconitate hydratase (NCBI) compare
b1361 ydaW -1.7 -1.1 orf, hypothetical protein (VIMSS) compare
b2284 nuoF -1.6 -3.8 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b3791 rffA -1.6 -5.2 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b2330 yfcB -1.6 -2.1 putative adenine-specific methylase (VIMSS) compare
b1604 ydgH -1.6 -5.6 hypothetical protein (NCBI) compare
b3192 yrbC -1.6 -4.9 predicted ABC-type organic solvent transporter (NCBI) compare
b3107 yhaL -1.6 -1.3 orf, hypothetical protein (VIMSS) compare
b3786 rffE -1.6 -7.2 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3195 yrbF -1.5 -6.9 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b4220 ytfM -1.5 -6.6 predicted outer membrane protein and surface antigen (NCBI) compare
b3193 yrbD -1.5 -7.5 predicted ABC-type organic solvent transporter (NCBI) compare
b3404 envZ -1.5 -5.0 osmolarity sensor protein (NCBI) compare
b2830 nudH -1.5 -1.4 dinucleoside polyphosphate hydrolase (NCBI) compare
b2017 yefM -1.5 -1.6 orf, hypothetical protein (VIMSS) compare
b4453 ldrD -1.5 -1.6 toxic polypeptide, small (NCBI) compare
b2617 smpA -1.4 -2.3 small membrane protein A (VIMSS) compare
b1252 tonB -1.4 -3.2 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b1480 sra -1.4 -1.6 30S ribosomal subunit protein S22 (NCBI) compare
b3787 rffD -1.4 -5.7 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b3790 rffC -1.4 -3.4 TDP-fucosamine acetyltransferase (RefSeq) compare
b3191 yrbB -1.4 -5.6 orf, hypothetical protein (VIMSS) compare
b1380 ldhA -1.4 -1.7 D-lactate dehydrogenase (NCBI) compare
b3769 ilvM -1.4 -2.4 acetolactate synthase II, small subunit (NCBI) compare
b4568 ytjA -1.4 -1.5 predicted protein (RefSeq) compare
b0114 aceE -1.4 -2.1 pyruvate dehydrogenase subunit E1 (NCBI) compare
b4535 yniD -1.3 -2.6 predicted protein (RefSeq) compare
b2346 vacJ -1.3 -4.5 predicted lipoprotein (NCBI) compare
b3811 xerC -1.3 -2.1 site-specific tyrosine recombinase XerC (NCBI) compare
b1486 ddpB -1.3 -2.5 D-ala-D-ala transporter subunit (NCBI) compare
b1591 b1591 -1.3 -1.7 putative oxidoreductase component (VIMSS) compare
b2280 nuoJ -1.3 -2.7 NADH dehydrogenase subunit J (NCBI) compare
b1281 pyrF -1.3 -2.4 orotidine 5'-phosphate decarboxylase (NCBI) compare
b4394 yjjX -1.3 -1.5 orf, hypothetical protein (VIMSS) compare
b4155 yjeA -1.3 -1.5 putative lysyl-tRNA synthetase (VIMSS) compare
b1827 kdgR -1.2 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b0178 hlpA -1.2 -2.5 periplasmic chaperone (NCBI) compare
b4509 ylcG -1.2 -1.6 DLP12 prophage; predicted protein (NCBI) compare
b2283 nuoG -1.2 -4.6 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b4221 ytfN -1.2 -7.7 hypothetical protein (NCBI) compare
b2279 nuoK -1.2 -1.4 NADH dehydrogenase subunit K (NCBI) compare
b3625 rfaY -1.2 -5.5 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1085 b1085 -1.2 -1.3 orf, hypothetical protein (VIMSS) compare
b1551 b1551 -1.2 -2.1 orf, hypothetical protein (VIMSS) compare
b0161 degP -1.2 -4.2 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b1639 ydhA -1.2 -3.8 orf, hypothetical protein (VIMSS) compare
b4570 lomR -1.2 -1.9 no description compare
b2071 yegJ -1.2 -2.8 hypothetical protein (NCBI) compare
b0502 ylbG -1.1 -1.1 no description compare
b1709 btuD -1.1 -1.2 vitamin B12-transporter ATPase (NCBI) compare
b3727 pstC -1.1 -4.0 phosphate transporter subunit (NCBI) compare
b3442 yhhZ -1.1 -2.3 hypothetical protein (NCBI) compare
b4458 oxyS -1.1 -0.8 global regulatory RNA (NCBI) compare
b2282 nuoH -1.1 -1.5 NADH dehydrogenase subunit H (NCBI) compare
b4651 yibW -1.1 -1.0 no description compare
b3250 mreC -1.1 -0.9 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b0471 ybaB -1.1 -1.8 hypothetical protein (NCBI) compare
b2620 smpB -1.1 -1.2 SsrA-binding protein (NCBI) compare
b2572 rseA -1.1 -3.4 anti-sigma factor (NCBI) compare
b1954 dsrA -1.1 -1.2 regulatory antisense RNA (NCBI) compare
b3388 damX -1.1 -7.0 hypothetical protein (NCBI) compare
b1286 rnb -1.1 -1.9 exoribonuclease II (NCBI) compare
b2055 wcaE -1.1 -2.4 predicted glycosyl transferase (NCBI) compare
b3121 yhaC -1.0 -1.2 hypothetical protein (NCBI) compare
b0890 ftsK -1.0 -4.3 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1176 minC -1.0 -3.1 septum formation inhibitor (NCBI) compare
b1861 ruvA -1.0 -1.2 Holliday junction DNA helicase motor protein (NCBI) compare
b3082 ygjM -1.0 -1.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b0998 torD -1.0 -0.9 chaperone protein TorD (NCBI) compare
b2432 yfeY -1.0 -2.0 hypothetical protein (NCBI) compare
b4480 hdfR -1.0 -2.3 transcriptional regulator HdfR (NCBI) compare
b4552 yrhC -1.0 -1.2 no description compare
b2110 yehC -1.0 -2.0 predicted periplasmic pilin chaperone (NCBI) compare
b3794 rffM -1.0 -4.3 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b0632 dacA -1.0 -3.1 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b4647 mokA -1.0 -0.8 no description compare
b0549 ybcO -1.0 -1.3 DLP12 prophage; predicted protein (NCBI) compare
b4533 ynfO -1.0 -1.6 Qin prophage; predicted protein (NCBI) compare
b1865 nudB -1.0 -1.1 dATP pyrophosphohydrolase (NCBI) compare
b2809 b2809 -0.9 -1.4 orf, hypothetical protein (VIMSS) compare
b1726 yniB -0.9 -1.4 predicted inner membrane protein (NCBI) compare
b1001 yccE -0.9 -1.6 hypothetical protein (NCBI) compare
b2297 pta -0.9 -1.1 phosphate acetyltransferase (NCBI) compare
b0436 tig -0.9 -3.2 trigger factor (NCBI) compare
b1347 ydaC -0.9 -1.5 Rac prophage; predicted protein (NCBI) compare
b2829 ptsP -0.9 -5.1 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b2258 b2258 -0.9 -0.9 putative transport/receptor protein (VIMSS) compare
b4642 yoeD -0.9 -1.1 no description compare
b4438 cyaR -0.9 -1.4 sRNA effector of ompX mRNA instability, cAMP-induced; hfq-dependent (RefSeq) compare
b3545 proK -0.9 -1.3 tRNA-Pro (NCBI) compare
b2318 truA -0.9 -1.6 tRNA pseudouridine synthase A (NCBI) compare
b3649 rpoZ -0.9 -1.1 DNA-directed RNA polymerase subunit omega (NCBI) compare
b2672 ygaM -0.9 -2.7 orf, hypothetical protein (VIMSS) compare
b3029 ygiN -0.9 -1.2 quinol monooxygenase (NCBI) compare
b1165 ymgA -0.9 -2.8 hypothetical protein (NCBI) compare
b1642 slyA -0.9 -1.1 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b2003 yeeT -0.9 -1.6 CP4-44 prophage; predicted protein (NCBI) compare
b1282 yciH -0.9 -2.4 orf, hypothetical protein (VIMSS) compare
b3068 ygjF -0.8 -2.6 G/U mismatch-specific DNA glycosylase (NCBI) compare
b2814 metZ -0.8 -0.9 tRNA-Met (NCBI) compare
b2168 fruK -0.8 -1.4 1-phosphofructokinase (NCBI) compare
b3609 secB -0.8 -2.2 export protein SecB (NCBI) compare
b2516 yfgA -0.8 -2.8 hypothetical protein (NCBI) compare
b1070 flgN -0.8 -0.7 export chaperone for FlgK and FlgL (NCBI) compare
b0234 yafP -0.8 -3.2 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b1383 ydbL -0.8 -2.2 orf, hypothetical protein (VIMSS) compare
b2124 yehS -0.8 -1.8 hypothetical protein (NCBI) compare
b3398 yrfF -0.8 -1.4 predicted inner membrane protein (NCBI) compare
b1159 mcrA -0.8 -1.8 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b0033 carB -0.8 -4.7 carbamoyl-phosphate synthase large subunit (NCBI) compare
b3889 yiiE -0.8 -2.2 predicted transcriptional regulator (RefSeq) compare
b0685 ybfE -0.8 -1.2 orf, hypothetical protein (VIMSS) compare
b4414 tff -0.8 -1.9 unknown RNA (NCBI) compare
b0616 citE -0.8 -2.2 citrate lyase beta chain (acyl lyase subunit) (VIMSS) compare
b4071 nrfB -0.8 -3.2 formate-dependent nitrite reductase; a penta-haeme cytochrome c (VIMSS) compare
b0705 ybfL -0.8 -1.8 putative receptor protein (VIMSS) compare
b3755 yieP -0.8 -3.0 predicted transcriptional regulator (NCBI) compare
b1326 mpaA -0.8 -2.0 murein peptide amidase A (RefSeq) compare
b4246 pyrL -0.8 -1.2 pyrBI operon leader peptide (NCBI) compare
b0627 tatE -0.8 -0.7 twin arginine translocase protein E (NCBI) compare
b4544 yfbW -0.8 -1.7 hypothetical protein (NCBI) compare
b4675 yoaJ -0.8 -1.4 expressed protein (RefSeq) compare
b0851 nfsA -0.7 -1.7 nitroreductase A, NADPH-dependent, FMN-dependent (NCBI) compare
b0001 thrL -0.7 -0.5 thr operon leader peptide (NCBI) compare
b3472 b3472 -0.7 -3.7 orf, hypothetical protein (VIMSS) compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Dodecanol in Escherichia coli BW25113

For carbon source Dodecanol across organisms