Experiment set7IT077 for Escherichia coli BW25113

Compare to:

Dodecanol carbon source

200 most important genes:

  gene name fitness t score description  
b1129 phoQ -6.3 -8.6 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b1130 phoP -6.1 -9.3 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b3026 qseC -5.7 -3.9 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b4702 mgtL -5.5 -3.8 regulatory leader peptide for mgtA (NCBI) compare
b0738 tolR -5.3 -3.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2282 nuoH -5.2 -5.1 NADH dehydrogenase subunit H (NCBI) compare
b4242 mgtA -5.2 -21.6 magnesium transporter (NCBI) compare
b0222 lpcA -5.0 -5.7 phosphoheptose isomerase (NCBI) compare
b0726 sucA -5.0 -3.5 alpha-ketoglutarate decarboxylase (NCBI) compare
b3631 rfaG -5.0 -26.3 glucosyltransferase I (NCBI) compare
b3620 rfaF -4.8 -8.6 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b1830 prc -4.7 -11.0 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b0720 gltA -4.7 -9.3 citrate synthase (NCBI) compare
b2830 nudH -4.6 -3.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b0053 surA -4.5 -4.4 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3630 rfaP -4.4 -19.8 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3619 rfaD -4.4 -7.3 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3621 rfaC -4.4 -10.1 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0462 acrB -4.0 -16.2 multidrug efflux system protein (NCBI) compare
b3035 tolC -4.0 -11.3 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3842 rfaH -4.0 -9.1 transcriptional activator RfaH (NCBI) compare
b1236 galU -3.9 -9.1 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3229 sspA -3.9 -7.0 stringent starvation protein A (NCBI) compare
b0463 acrA -3.7 -9.6 multidrug efflux system (NCBI) compare
b2285 nuoE -3.7 -3.9 NADH dehydrogenase subunit E (NCBI) compare
b3725 pstB -3.7 -2.5 phosphate transporter subunit (NCBI) compare
b3236 mdh -3.6 -8.7 malate dehydrogenase (NCBI) compare
b2287 nuoB -3.6 -4.8 NADH dehydrogenase subunit B (NCBI) compare
b0145 dksA -3.6 -6.4 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3741 gidA -3.6 -11.8 glucose-inhibited division protein A (NCBI) compare
b2512 yfgL -3.5 -8.6 protein assembly complex, lipoprotein component (NCBI) compare
b3405 ompR -3.5 -7.3 osmolarity response regulator (NCBI) compare
b1677 lpp -3.3 -4.3 murein lipoprotein (NCBI) compare
b2284 nuoF -3.2 -7.1 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b0739 tolA -3.2 -6.1 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0740 tolB -3.1 -7.6 translocation protein TolB precursor (NCBI) compare
b0200 gmhB -3.1 -3.5 hypothetical protein (NCBI) compare
b2283 nuoG -2.9 -8.4 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b0737 tolQ -2.9 -4.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4481 rffT -2.9 -6.5 4-alpha-L-fucosyltransferase (NCBI) compare
b3632 rfaQ -2.8 -17.9 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3728 pstS -2.8 -6.8 phosphate transporter subunit (NCBI) compare
b3463 ftsE -2.8 -6.8 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b3706 trmE -2.7 -6.4 tRNA modification GTPase (NCBI) compare
b3627 rfaI -2.7 -12.8 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b3052 rfaE -2.7 -6.3 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3791 rffA -2.7 -8.9 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b2276 nuoN -2.6 -5.6 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b0114 aceE -2.6 -4.6 pyruvate dehydrogenase subunit E1 (NCBI) compare
b0688 pgm -2.5 -4.1 phosphoglucomutase (NCBI) compare
b3839 tatC -2.5 -8.9 TatABCE protein translocation system subunit (NCBI) compare
b3163 nlpI -2.5 -5.7 hypothetical protein (NCBI) compare
b3082 ygjM -2.5 -2.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b1192 ldcA -2.5 -5.7 L,D-carboxypeptidase A (NCBI) compare
b2280 nuoJ -2.5 -5.0 NADH dehydrogenase subunit J (NCBI) compare
b0741 pal -2.5 -5.3 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2286 nuoC -2.4 -4.0 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b3790 rffC -2.4 -5.0 TDP-fucosamine acetyltransferase (RefSeq) compare
b0088 murD -2.3 -2.6 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b3811 xerC -2.2 -4.4 site-specific tyrosine recombinase XerC (NCBI) compare
b1861 ruvA -2.2 -2.6 Holliday junction DNA helicase motor protein (NCBI) compare
b3628 rfaB -2.1 -10.6 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b3462 ftsX -2.1 -6.3 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b1863 ruvC -2.0 -4.2 Holliday junction resolvase (NCBI) compare
b2281 nuoI -2.0 -3.6 NADH dehydrogenase subunit I (NCBI) compare
b0232 yafN -2.0 -1.5 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b4653 yicT -1.9 -1.7 no description compare
b3806 cyaA -1.9 -6.0 adenylate cyclase (NCBI) compare
b3794 rffM -1.9 -6.3 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b0683 fur -1.9 -2.7 ferric uptake regulator (NCBI) compare
b3727 pstC -1.9 -6.2 phosphate transporter subunit (NCBI) compare
b4172 hfq -1.8 -2.4 RNA-binding protein Hfq (NCBI) compare
b3784 rfe -1.8 -10.5 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b0957 ompA -1.8 -2.9 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3613 yibP -1.8 -5.3 putative membrane protein (VIMSS) compare
b1860 ruvB -1.8 -2.6 Holliday junction DNA helicase B (NCBI) compare
b3261 fis -1.7 -3.3 DNA-binding protein Fis (NCBI) compare
b2741 rpoS -1.7 -4.7 RNA polymerase sigma factor (NCBI) compare
b3935 priA -1.7 -3.3 primosome assembly protein PriA (NCBI) compare
b2051 wcaH -1.7 -0.9 GDP-mannose mannosyl hydrolase (VIMSS) compare
b2297 pta -1.7 -2.6 phosphate acetyltransferase (NCBI) compare
b3194 yrbE -1.7 -6.8 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2279 nuoK -1.7 -1.4 NADH dehydrogenase subunit K (NCBI) compare
b0890 ftsK -1.7 -7.2 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1167 ymgC -1.6 -1.8 hypothetical protein (NCBI) compare
b2215 ompC -1.6 -6.2 outer membrane porin protein C (NCBI) compare
b0051 ksgA -1.6 -4.5 dimethyladenosine transferase (NCBI) compare
b3786 rffE -1.6 -7.9 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3649 rpoZ -1.6 -2.3 DNA-directed RNA polymerase subunit omega (NCBI) compare
b2277 nuoM -1.6 -4.8 NADH dehydrogenase subunit M (NCBI) compare
b3787 rffD -1.5 -7.9 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b2017 yefM -1.5 -1.9 orf, hypothetical protein (VIMSS) compare
b1960 vsr -1.5 -2.9 DNA mismatch endonuclease of very short patch repair (NCBI) compare
b3442 yhhZ -1.5 -3.9 hypothetical protein (NCBI) compare
b2278 nuoL -1.5 -5.8 NADH dehydrogenase subunit L (NCBI) compare
b2330 yfcB -1.5 -2.7 putative adenine-specific methylase (VIMSS) compare
b2346 vacJ -1.5 -7.2 predicted lipoprotein (NCBI) compare
b3164 pnp -1.5 -3.6 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1604 ydgH -1.5 -3.3 hypothetical protein (NCBI) compare
b4171 miaA -1.4 -3.7 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b2820 recB -1.4 -2.9 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2058 wcaB -1.4 -1.3 predicted acyl transferase (NCBI) compare
b0437 clpP -1.4 -5.9 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3250 mreC -1.4 -1.2 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b0548 ninE -1.4 -4.0 DLP12 prophage; conserved protein (NCBI) compare
b3726 pstA -1.4 -4.5 phosphate transporter subunit (NCBI) compare
b4139 aspA -1.4 -6.4 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b3195 yrbF -1.3 -6.5 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b0888 trxB -1.3 -2.7 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3404 envZ -1.3 -4.5 osmolarity sensor protein (NCBI) compare
b4220 ytfM -1.3 -7.2 predicted outer membrane protein and surface antigen (NCBI) compare
b2168 fruK -1.3 -2.2 1-phosphofructokinase (NCBI) compare
b2617 smpA -1.2 -1.9 small membrane protein A (VIMSS) compare
b0221 yafH -1.2 -6.7 putative acyl-CoA dehydrogenase (EC 1.3.99.-) (VIMSS) compare
b3386 rpe -1.2 -2.0 ribulose-phosphate 3-epimerase (NCBI) compare
b3469 zntA -1.2 -6.3 zinc, cobalt and lead efflux system (NCBI) compare
b4221 ytfN -1.2 -8.2 hypothetical protein (NCBI) compare
b2699 recA -1.2 -1.8 recombinase A (NCBI) compare
b0438 clpX -1.2 -5.3 ATP-dependent protease ATP-binding subunit (NCBI) compare
b4480 hdfR -1.1 -3.4 transcriptional regulator HdfR (NCBI) compare
b3341 rpsG -1.1 -1.0 30S ribosomal protein S7 (NCBI) compare
b3863 polA -1.1 -1.2 DNA polymerase I (NCBI) compare
b3388 damX -1.1 -7.4 hypothetical protein (NCBI) compare
b4508 peaD -1.1 -1.8 putative sensory transduction regulator (VIMSS) compare
b2318 truA -1.1 -3.4 tRNA pseudouridine synthase A (NCBI) compare
b3504 yhiS -1.1 -2.9 hypothetical protein (RefSeq) compare
b0161 degP -1.1 -4.8 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b3193 yrbD -1.1 -5.3 predicted ABC-type organic solvent transporter (NCBI) compare
b2894 xerD -1.0 -1.0 site-specific tyrosine recombinase XerD (NCBI) compare
b2189 proL -1.0 -1.9 tRNA-Pro (NCBI) compare
b1001 yccE -1.0 -1.6 hypothetical protein (NCBI) compare
b3846 fadB -1.0 -5.6 fused 3-hydroxybutyryl-CoA epimerase/delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase/enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase (NCBI) compare
b4613 dinQ -1.0 -1.7 Damage inducible, function unknown (RefSeq) compare
b4203 rplI -1.0 -3.5 50S ribosomal protein L9 (NCBI) compare
b1185 dsbB -1.0 -2.7 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b0632 dacA -1.0 -4.2 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b3764 yifE -1.0 -2.7 hypothetical protein (NCBI) compare
b0630 lipB -1.0 -1.3 protein of lipoate biosynthesis (VIMSS) compare
b2572 rseA -0.9 -3.0 anti-sigma factor (NCBI) compare
b1105 ycfM -0.9 -2.8 predicted outer membrane lipoprotein (NCBI) compare
b1150 ymfR -0.9 -1.0 e14 prophage; predicted protein (NCBI) compare
b3260 dusB -0.9 -3.6 tRNA-dihydrouridine synthase B (NCBI) compare
b3191 yrbB -0.9 -4.4 orf, hypothetical protein (VIMSS) compare
b2809 b2809 -0.9 -1.8 orf, hypothetical protein (VIMSS) compare
b2288 nuoA -0.9 -1.1 NADH dehydrogenase I chain A (VIMSS) compare
b1984 asnW -0.9 -0.9 tRNA-Asn (NCBI) compare
b0178 hlpA -0.9 -2.6 periplasmic chaperone (NCBI) compare
b0729 sucD -0.9 -1.8 succinyl-CoA synthetase subunit alpha (NCBI) compare
b3121 yhaC -0.9 -1.8 hypothetical protein (NCBI) compare
b4042 dgkA -0.9 -2.2 diacylglycerol kinase (NCBI) compare
b1324 tpx -0.9 -3.1 thiol peroxidase (NCBI) compare
b3398 yrfF -0.8 -1.6 predicted inner membrane protein (NCBI) compare
b0357 yaiN -0.8 -2.1 putative alpha helix chain (VIMSS) compare
b3792 wzxE -0.8 -4.3 O-antigen translocase (NCBI) compare
b3192 yrbC -0.8 -4.2 predicted ABC-type organic solvent transporter (NCBI) compare
b2513 yfgM -0.8 -2.0 hypothetical protein (NCBI) compare
b2080 b2080 -0.8 -1.2 orf, hypothetical protein (VIMSS) compare
b3625 rfaY -0.8 -4.8 lipopolysaccharide core biosynthesis protein (NCBI) compare
b4155 yjeA -0.8 -1.2 putative lysyl-tRNA synthetase (VIMSS) compare
b1281 pyrF -0.8 -1.6 orotidine 5'-phosphate decarboxylase (NCBI) compare
b1928 yedD -0.8 -3.0 hypothetical protein (NCBI) compare
b2829 ptsP -0.8 -5.2 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b4529 ydbJ -0.8 -1.0 hypothetical protein (NCBI) compare
b4577 sgrS -0.8 -1.4 small antisense RNA (NCBI) compare
b4373 rimI -0.8 -2.0 ribosomal-protein-alanine N-acetyltransferase (NCBI) compare
b4685 yrbN -0.8 -1.2 expressed protein (RefSeq) compare
b0092 ddlB -0.8 -1.8 D-alanylalanine synthetase (NCBI) compare
b1429 tehA -0.8 -1.1 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b4618 tisB -0.8 -1.7 lexA-regulated toxic peptide (RefSeq) compare
b3860 dsbA -0.7 -4.4 periplasmic protein disulfide isomerase I (NCBI) compare
b1805 fadD -0.7 -4.6 acyl-CoA synthase (NCBI) compare
b4522 yciX_1 -0.7 -2.3 hypothetical protein (NCBI) compare
b2300 yfcE -0.7 -2.6 orf, hypothetical protein (VIMSS) compare
b1273 yciN -0.7 -1.5 hypothetical protein (NCBI) compare
b4294 insA-7 -0.7 -1.1 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b3053 glnE -0.7 -3.3 fused deadenylyltransferase/adenylyltransferase for glutamine synthetase (NCBI) compare
b1511 ydeV -0.7 -1.7 putative kinase (VIMSS) compare
b2205 napG -0.7 -3.2 quinol dehydrogenase periplasmic component (NCBI) compare
b0131 panD -0.7 -1.6 aspartate 1-decarboxylase precursor (NCBI) compare
b1977 asnT -0.7 -1.6 tRNA-Asn (NCBI) compare
b4246 pyrL -0.7 -1.1 pyrBI operon leader peptide (NCBI) compare
b2516 yfgA -0.7 -3.2 hypothetical protein (NCBI) compare
b4676 yoaK -0.7 -0.8 expressed protein (RefSeq) compare
b4407 thiS -0.7 -0.5 sulfur carrier protein ThiS (NCBI) compare
b0848 ybjM -0.7 -2.6 predicted inner membrane protein (NCBI) compare
b2071 yegJ -0.7 -2.4 hypothetical protein (NCBI) compare
b2679 proX -0.7 -1.7 glycine betaine transporter subunit (NCBI) compare
b3226 yhcK -0.7 -2.7 putative FADA-type transcriptional regulator (VIMSS) compare
b2822 recC -0.7 -2.0 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b1305 pspB -0.7 -1.4 phage shock protein B (NCBI) compare
b3838 tatB -0.7 -2.2 sec-independent translocase (NCBI) compare
b2853 ygeI -0.7 -1.1 hypothetical protein (NCBI) compare
b3133 agaV -0.7 -1.6 PTS system, cytoplasmic, N-acetylgalactosamine-specific IIB component 2 (EIIB-AGA) (VIMSS) compare
b1890 motA -0.7 -2.5 flagellar motor protein MotA (NCBI) compare
b1819 manZ -0.6 -2.6 mannose-specific enzyme IID component of PTS (NCBI) compare
b4093 phnO -0.6 -3.4 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b0999 cbpM -0.6 -0.9 modulator of CbpA co-chaperone (NCBI) compare
b0736 ybgC -0.6 -1.8 predicted acyl-CoA thioesterase (NCBI) compare
b1088 yceD -0.6 -2.3 hypothetical protein (NCBI) compare
b2754 ygbF -0.6 -1.3 orf, hypothetical protein (VIMSS) compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Dodecanol in Escherichia coli BW25113

For carbon source Dodecanol across organisms