Experiment set7IT062 for Pseudomonas putida KT2440

Compare to:

D-Lysine 10 mM carbon source

200 most important genes:

  gene name fitness t score description  
PP_3591 -6.3 -4.4 Delta 1-piperideine-2-carboxylate reductase compare
PP_4108 -5.9 -5.8 2-aminoadipate transaminase (EC 2.6.1.39) (from data) compare
PP_0292 -5.9 -4.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_0422 -5.8 -5.7 Indole-3-glycerol phosphate synthase compare
PP_3511 -5.7 -9.5 Branched-chain-amino-acid aminotransferase compare
PP_0966 -5.5 -12.4 Histidinol dehydrogenase compare
PP_3594 -5.5 -8.4 L-lysine and D-lysine ABC transporter, permease component 1 (from data) compare
PP_4493 -5.4 -17.1 D-2-hydroxyglutarate dehydrogenase (EC 1.1.99.39) (from data) compare
PP_4680 -5.4 -15.2 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_1986 -5.3 -3.7 3-isopropylmalate dehydratase small subunit compare
PP_0967 -5.2 -12.2 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_0293 -5.2 -3.2 Imidazole glycerol phosphate synthase subunit HisF compare
PP_0290 -5.1 -9.2 Imidazole glycerol phosphate synthase subunit HisH compare
PP_3593 -4.9 -11.2 L-lysine and D-lysine ABC transporter, substrate-binding component (from data) compare
PP_5098 -4.8 -10.3 methionine biosynthesis protein MetW compare
PP_4679 -4.7 -8.4 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5257 -4.7 -13.5 L-pipecolate oxidase compare
PP_5014 -4.7 -3.2 Phosphoribosyl-AMP cyclohydrolase compare
PP_5085 -4.7 -7.7 malic enzyme B compare
PP_1995 -4.6 -10.7 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_1985 -4.6 -6.8 3-isopropylmalate dehydratase large subunit compare
PP_2370 -4.6 -4.4 conserved protein of unknown function compare
PP_5347 -4.5 -12.6 pyruvate carboxylase subunit A compare
PP_5095 -4.5 -3.1 pyrroline-5-carboxylate reductase compare
PP_5258 -4.5 -8.6 L-piperidine-6-carboxylate dehydrogenase compare
PP_0083 -4.5 -5.3 tryptophan synthase beta chain compare
PP_2088 -4.4 -4.0 RNA polymerase sigma factor SigX compare
PP_4678 -4.3 -14.1 Ketol-acid reductoisomerase compare
PP_1079 -4.3 -7.7 Ornithine carbamoyltransferase compare
PP_4909 -4.3 -9.5 phosphoserine phosphatase compare
PP_3597 -4.3 -5.5 L-lysine and D-lysine ABC transporter, ATPase component (from data) compare
PP_4890 -4.2 -5.9 ATP phosphoribosyltransferase regulatory subunit compare
PP_0082 -4.2 -5.7 tryptophan synthase alpha chain compare
PP_5185 -4.1 -7.4 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_3592 -4.1 -9.9 Transcriptional regulator, RpiR family compare
PP_0417 -4.1 -15.6 Anthranilate synthase component 1 compare
PP_5097 -4.1 -14.3 homoserine O-acetyltransferase compare
PP_3595 -4.0 -7.8 L-lysine and D-lysine ABC transporter, permease component 2 (from data) compare
PP_5346 -4.0 -9.9 pyruvate carboxylase subunit B compare
PP_1988 -4.0 -9.6 3-isopropylmalate dehydrogenase compare
PP_4696 -4.0 -6.6 Nitrogen regulation protein NR(I) compare
PP_5015 -3.9 -3.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_2001 -3.9 -8.7 O-succinylhomoserine sulfhydrylase compare
PP_1088 -3.9 -12.2 Argininosuccinate synthase compare
PP_2371 -3.9 -8.5 Sulphite reductase hemoprotein, beta subunit compare
PP_0184 -3.9 -7.9 Argininosuccinate lyase compare
PP_0420 -3.8 -10.3 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_5128 -3.8 -7.6 Dihydroxy-acid dehydratase compare
PP_0965 -3.8 -7.7 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_0691 -3.7 -5.1 Glutamate 5-kinase compare
PP_2327 -3.7 -6.8 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_3596 -3.7 -7.8 D-lysine oxidase compare
PP_5155 -3.3 -5.2 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_1231 -3.3 -6.7 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_2328 -3.2 -8.4 Phosphoadenosine phosphosulfate reductase compare
PP_0735 -3.2 -1.6 molybdopterin-synthase adenylyltransferase compare
PP_0787 -3.2 -4.5 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_5114 -3.2 -3.1 putative adenine methyltransferase compare
PP_3999 -3.1 -7.2 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_4122 -3.1 -2.1 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_0421 -3.1 -8.3 Anthranilate phosphoribosyltransferase compare
PP_5348 -3.0 -7.9 Transcriptional regulator, LysR family compare
PP_0289 -3.0 -6.7 Imidazoleglycerol-phosphate dehydratase compare
PP_1994 -3.0 -2.8 tRNA pseudouridine (38-40)synthase compare
PP_5289 -2.9 -3.9 Acetylglutamate kinase compare
PP_4695 -2.7 -10.2 Sensory box histidine kinase compare
PP_4724 -2.7 -5.0 Carbamoyl-phosphate synthase small chain compare
PP_1025 -2.6 -10.1 2-isopropylmalate synthase compare
PP_4723 -2.5 -9.3 Carbamoyl-phosphate synthase large chain compare
PP_0339 -2.5 -4.7 Pyruvate dehydrogenase E1 component compare
PP_1344 -2.4 -2.9 conserved protein of unknown function compare
PP_t12 -2.4 -1.4 tRNA-Thr compare
PP_5260 -2.4 -6.2 2-oxoadipate decarboxylase/hydroxylase (2-hydroxyglutarate synthase) (from data) compare
PP_1109 -2.2 -9.6 Transcriptional regulator, GntR family compare
PP_2087 -2.2 -4.4 CmpX protein compare
PP_4999 -2.1 -2.8 dihydroorotase-like protein compare
PP_1099 -2.1 -2.2 Cold shock protein CapB compare
PP_4126 -2.1 -2.3 NADH-quinone oxidoreductase subunit I compare
PP_0291 -2.1 -2.6 conserved protein of unknown function compare
PP_1654 -2.1 -3.5 cysteine synthase B compare
PP_5217 -2.0 -12.6 Polyphosphate kinase compare
PP_2433 -2.0 -3.1 conserved protein of unknown function compare
PP_4782 -1.9 -3.6 Phosphomethylpyrimidine kinase compare
PP_1664 -1.9 -4.1 phosphoribosylglycinamide formyltransferase 1 compare
PP_4124 -1.9 -4.3 NADH-quinone oxidoreductase subunit G compare
PP_4910 -1.9 -2.1 conserved protein of unknown function compare
PP_4693 -1.9 -5.4 RNA polymerase-binding transcription factor DksA compare
PP_1233 -1.9 -3.5 sulfurtransferase compare
PP_4700 -1.9 -1.3 pantothenate synthetase compare
PP_5017 -1.9 -1.4 Sec-independent protein translocase protein TatB compare
PP_1679 -1.9 -2.0 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_0833 -1.8 -2.4 queuine tRNA-ribosyltransferase compare
PP_3043 -1.8 -3.6 conserved protein of unknown function compare
PP_5008 -1.8 -1.7 Poly granule-associated protein compare
PP_4342 -1.8 -4.2 flagellar synthesis regulator, putative ATPase compare
PP_1348 -1.7 -5.5 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase compare
PP_1111 -1.7 -5.5 putative Synthetase compare
PP_1734 -1.7 -3.9 Probable septum site-determining protein MinC compare
PP_5007 -1.6 -2.1 Polyhydroxyalkanoate granule-associated protein GA2 compare
PP_4364 -1.6 -3.1 putative Anti-sigma F factor antagonist compare
PP_4532 -1.6 -1.6 ATP-dependent DEAD-box RNA helicase require for 50S ribosomal subunit biogenesis compare
PP_3603 -1.6 -4.3 Transcriptional regulator, GntR family compare
PP_1716 -1.6 -2.1 Transcriptional regulator, Cro/CI family compare
PP_4830 -1.5 -5.4 precorrin-6Y C(5,15)-methyltransferase compare
PP_2820 -1.5 -2.6 HTH-type transcriptional regulator nfxB compare
PP_1764 -1.5 -4.6 Phosphoglycolate phosphatase 2 compare
PP_4131 -1.5 -5.2 NADH-quinone oxidoreductase subunit N compare
PP_4902 -1.5 -3.1 Oligoribonuclease compare
PP_0063 -1.5 -4.4 putative Lipid A biosynthesis lauroyl acyltransferase compare
PP_0383 -1.5 -6.0 Lysine 2-monooxygenase compare
PP_3505 -1.5 -1.8 conserved protein of unknown function compare
PP_5104 -1.5 -4.5 thiazole synthase compare
PP_4922 -1.5 -6.7 Phosphomethylpyrimidine synthase compare
PP_0155 -1.4 -8.0 pyridine nucleotide transhydrogenase, beta subunit compare
PP_4471 -1.4 -4.0 Magnesium transporter compare
PP_4799 -1.4 -2.5 putative Muramoyltetrapeptide carboxypeptidase compare
PP_0937 -1.4 -3.7 endoribonuclease G (RNAse G) compare
PP_3508 -1.4 -2.9 Protein CobW compare
PP_4494 -1.4 -4.8 putative LysR-type transcriptional activator protein compare
PP_0949 -1.4 -5.6 putative ATP-binding protein UPF0042 compare
PP_1632 -1.4 -1.9 conserved protein of unknown function compare
PP_0156 -1.4 -4.9 pyridine nucleotide transhydrogenase subunit alpha compare
PP_2302 -1.4 -3.9 DNA-binding, ATP-dependent protease compare
PP_2402 -1.4 -2.1 putative Sensor histidine kinase compare
PP_5028 -1.4 -3.2 proline iminopeptidase compare
PP_4937 -1.4 -3.5 toluene tolerance protein compare
PP_1428 -1.4 -1.6 Sigma factor AlgU negative regulatory protein compare
PP_4895 -1.4 -3.1 tRNA dimethylallyltransferase compare
PP_1938 -1.4 -2.6 conserved protein of unknown function compare
PP_5303 -1.4 -3.0 aminoacrylate/iminopropionate hydrolase/deaminase compare
PP_1122 -1.4 -1.6 OmpA family protein compare
PP_2898 -1.3 -2.4 conserved exported protein of unknown function compare
PP_3590 -1.3 -4.3 aromatic-amino-acid transaminase (EC 2.6.1.57) (from data) compare
PP_3539 -1.3 -1.6 putative Transcriptional regulator compare
PP_1216 -1.3 -1.5 Holliday junction ATP-dependent DNA helicase RuvA compare
PP_2725 -1.3 -3.2 Protease PfpI compare
PP_4121 -1.3 -3.6 NADH-quinone oxidoreductase subunit C/D compare
PP_5216 -1.3 -2.1 exopolyphosphatase compare
PP_0213 -1.3 -2.9 succinate-semialdehyde dehydrogenase (NADP+) compare
PP_3946 -1.3 -1.1 HTH-type transcriptional repressor NicR compare
PP_1826 -1.3 -1.8 Hydrolase, isochorismatase family compare
PP_0382 -1.3 -5.9 5-aminopentanamidase compare
PP_4860 -1.3 -7.1 putative Mannose-6-phosphate isomerase compare
PP_1366 -1.2 -0.8 Transcriptional regulator MvaT, P16 subunit compare
PP_4699 -1.2 -2.5 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PP_2181 -1.2 -2.6 Transcriptional regulator, Cro/CI family compare
PP_1676 -1.2 -3.5 subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_4666 -1.2 -5.0 3-hydroxyisobutyrate dehydrogenase compare
PP_4847 -1.1 -2.1 chaperone modulatory of CbpA co-chaperone protein compare
PP_3346 -1.1 -1.8 Nickel transporter ATP-binding protein compare
PP_5639 -1.1 -4.2 conserved exported protein of unknown function compare
PP_3409 -1.1 -1.9 putative Cobalamin biosynthesis protein cobE compare
PP_5706 -1.1 -1.7 Sec translocation complex - SecG subunit compare
PP_2168 -1.1 -5.1 Transaldolase compare
PP_3312 -1.1 -1.1 putative Heat shock protein compare
PP_0401 -1.1 -1.6 Ribosomal RNA small subunit methyltransferase A compare
PP_4223 -1.1 -1.8 diaminobutyrate-2-oxoglutarate transaminase compare
PP_3559 -1.1 -3.8 glycine betaine ABC transporter (permease) compare
PP_5747 -1.1 -4.0 pyridine nucleotide transhydrogenase subunit alpha compare
PP_4424 -1.1 -1.9 Uncharacterized HTH-type transcriptional regulator y4tD compare
PP_0405 -1.1 -7.1 conserved protein of unknown function compare
PP_2136 -1.1 -2.7 enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase compare
PP_1022 -1.0 -3.4 glucose 6-phosphate-1-dehydrogenase compare
PP_3065 -1.0 -3.4 Pyocin R2_PP, tail formation compare
PP_5000 -1.0 -0.9 peptidase component of the ATP-dependent HslVU protease compare
PP_1142 -1.0 -1.4 conserved protein of unknown function compare
PP_2337 -1.0 -1.8 aconitate isomerase compare
PP_2976 -1.0 -1.1 putative transposase compare
PP_0878 -1.0 -4.1 dipeptide ABC transporter, binding subunit compare
PP_2539 -1.0 -3.7 Transcriptional regulator, LysR family compare
PP_5533 -1.0 -1.4 conserved protein of unknown function compare
PP_4546 -1.0 -2.6 ATP-dependent helicase HrpA compare
PP_2029 -1.0 -2.2 von Willebrand factor type A domain protein compare
PP_1656 -1.0 -5.1 ATP:GTP 3'-pyrophosphotransferase compare
PP_1736 -1.0 -1.1 conserved protein of unknown function compare
PP_4247 -1.0 -1.6 Exonuclease compare
PP_1068 -1.0 -3.6 glutamate / aspartate ABC transporter - ATP binding subunit compare
PP_3951 -1.0 -2.6 3-oxoadipate CoA-transferase subunit A compare
PP_0414 -1.0 -2.2 Polyamine ABC transporter, permease protein compare
PP_1733 -1.0 -1.7 membrane ATPase of the MinC-MinD-MinE system compare
PP_2145 -1.0 -2.6 beta-N-acetylglucosaminidase compare
PP_3808 -1.0 -1.5 Antibiotic synthesis protein MbtH compare
PP_2716 -1.0 -2.0 arsenate reductase compare
PP_3840 -1.0 -1.1 conserved protein of unknown function compare
PP_3810 -1.0 -2.0 conserved protein of unknown function compare
PP_3507 -1.0 -5.0 Aerobic cobaltochelatase subunit CobN compare
PP_4977 -0.9 -4.7 5,10-methylenetetrahydrofolate reductase compare
PP_4952 -0.9 -0.8 ATP-dependent RNA helicase, specific for 23S rRNA compare
PP_3952 -0.9 -4.4 3-oxoadipate CoA-transferase subunit A compare
PP_5035 -0.9 -3.4 Histidine utilization repressor compare
PP_2880 -0.9 -1.6 Transcriptional regulator, TetR family compare
PP_1637 -0.9 -2.8 Transcriptional regulator, LysR family compare
PP_4880 -0.9 -4.7 exoribonuclease R compare
PP_2375 -0.9 -5.6 cobalamin-dependent methionine synthase compare
PP_1864 -0.9 -2.6 conserved protein of unknown function compare
PP_2030 -0.9 -2.5 conserved protein of unknown function compare
PP_4824 -0.9 -4.0 Sensor histidine kinase/response regulator compare
PP_1672 -0.9 -2.0 cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase compare
PP_t11 -0.9 -1.9 tRNA-Lys compare
PP_4827 -0.9 -4.9 Precorrin-2 C(20)-methyltransferase compare


Specific Phenotypes

For 19 genes in this experiment

For carbon source D-Lysine in Pseudomonas putida KT2440

For carbon source D-Lysine across organisms