Experiment set7IT060 for Pseudomonas fluorescens GW456-L13

Compare to:

LB control

200 most detrimental genes:

  gene name fitness t score description  
PfGW456L13_672 +1.1 4.0 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
PfGW456L13_4231 +1.0 2.7 hypothetical protein compare
PfGW456L13_3774 +1.0 1.4 Organic hydroperoxide resistance protein compare
PfGW456L13_1848 +1.0 1.6 hypothetical protein compare
PfGW456L13_477 +0.9 2.0 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
PfGW456L13_4069 +0.9 2.9 Heavy-metal-associated domain (N-terminus) and membrane-bounded cytochrome biogenesis cycZ-like domain, possible membrane copper tolerance protein compare
PfGW456L13_5121 +0.9 1.2 hypothetical protein compare
PfGW456L13_1916 +0.9 2.5 hypothetical protein compare
PfGW456L13_3232 +0.8 1.1 hypothetical protein compare
PfGW456L13_1099 +0.8 1.4 FIG00953563: hypothetical protein compare
PfGW456L13_481 +0.8 2.6 transcriptional regulator, Crp/Fnr family compare
PfGW456L13_2608 +0.8 2.1 Peptidyl-prolyl cis-trans isomerase PpiB (EC 5.2.1.8) compare
PfGW456L13_1731 +0.8 1.9 NADH:flavin oxidoreductases, Old Yellow Enzyme family compare
PfGW456L13_4162 +0.8 2.1 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) compare
PfGW456L13_3646 +0.7 3.1 Transporter, LysE family compare
PfGW456L13_2232 +0.7 3.0 FIG00957049: hypothetical protein compare
PfGW456L13_3512 +0.7 2.3 Alcohol dehydrogenase (EC 1.1.1.1); Acetaldehyde dehydrogenase (EC 1.2.1.10) compare
PfGW456L13_2854 +0.7 3.2 CobW GTPase involved in cobalt insertion for B12 biosynthesis compare
PfGW456L13_1017 +0.7 2.5 Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR compare
PfGW456L13_2281 +0.7 2.2 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
PfGW456L13_3466 +0.7 2.2 Probable vanillate O-demethylase oxygenase subunit oxidoreductase protein (EC 1.14.13.-) compare
PfGW456L13_4565 +0.7 2.3 Beta-propeller domains of methanol dehydrogenase type compare
PfGW456L13_62 +0.7 1.3 hypothetical protein compare
PfGW456L13_5074 +0.7 1.3 1-phosphofructokinase (EC 2.7.1.56) compare
PfGW456L13_3047 +0.7 1.5 Response regulator compare
PfGW456L13_4640 +0.7 2.1 FIG00955308: hypothetical protein compare
PfGW456L13_1027 +0.6 1.9 Chemotaxis signal transduction protein compare
PfGW456L13_705 +0.6 1.0 FIG00953800: hypothetical protein compare
PfGW456L13_1789 +0.6 0.9 FIG00954094: hypothetical protein compare
PfGW456L13_936 +0.6 2.8 Thiol-disulfide isomerase and thioredoxins compare
PfGW456L13_2541 +0.6 2.1 Sodium:dicarboxylate symporter compare
PfGW456L13_1238 +0.6 1.0 Biotin operon repressor / Biotin-protein ligase (EC 6.3.4.15) compare
PfGW456L13_4944 +0.6 1.2 FIG00963370: hypothetical protein compare
PfGW456L13_2038 +0.6 1.6 hypothetical protein compare
PfGW456L13_3629 +0.6 1.1 Lactoylglutathione lyase and related lyases compare
PfGW456L13_3847 +0.6 3.2 Predicted secretion system X protein GspE-like compare
PfGW456L13_613 +0.6 2.1 hypothetical protein compare
PfGW456L13_1611 +0.6 1.7 FIG00954698: hypothetical protein compare
PfGW456L13_2920 +0.6 1.2 FIG00962345: hypothetical protein compare
PfGW456L13_2821 +0.6 1.8 DNA polymerase-like protein PA0670 compare
PfGW456L13_4259 +0.6 1.0 FIG00953296: hypothetical protein compare
PfGW456L13_4321 +0.6 1.8 Positive regulator of CheA protein activity (CheW) compare
PfGW456L13_965 +0.6 3.4 FIG00954147: hypothetical protein compare
PfGW456L13_5039 +0.5 2.0 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) compare
PfGW456L13_3181 +0.5 0.7 Organic hydroperoxide resistance protein compare
PfGW456L13_4937 +0.5 2.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
PfGW456L13_4070 +0.5 3.3 Coproporphyrinogen III oxidase, oxygen-independent (EC 1.3.99.22) compare
PfGW456L13_5047 +0.5 4.4 ABC transporter, ATP-binding protein compare
PfGW456L13_2103 +0.5 2.1 Phosphate:acyl-ACP acyltransferase PlsX compare
PfGW456L13_4392 +0.5 2.1 Periplasmic nitrate reductase component NapE compare
PfGW456L13_3591 +0.5 2.1 hypothetical protein compare
PfGW456L13_3444 +0.5 1.2 Transcriptional regulator, TetR family compare
PfGW456L13_3836 +0.5 2.4 Decarboxylase family protein compare
PfGW456L13_757 +0.5 1.9 Phosphate transport system regulatory protein PhoU compare
PfGW456L13_2268 +0.5 1.8 Thiol-disulfide isomerase and thioredoxins compare
PfGW456L13_405 +0.5 2.2 FIG001957: putative hydrolase compare
PfGW456L13_4851 +0.5 2.3 Exodeoxyribonuclease VII large subunit (EC 3.1.11.6) compare
PfGW456L13_4125 +0.5 0.7 Phosphoadenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.8) / Adenylyl-sulfate reductase [thioredoxin] (EC 1.8.4.10) compare
PfGW456L13_236 +0.5 1.5 Acyl carrier protein (ACP1) compare
PfGW456L13_4036 +0.5 1.0 FIG00954079: hypothetical protein compare
PfGW456L13_2006 +0.5 2.3 hypothetical protein compare
PfGW456L13_4007 +0.5 1.0 Phosphomannomutase (EC 5.4.2.8) compare
PfGW456L13_849 +0.5 2.3 Regulator of nucleoside diphosphate kinase compare
PfGW456L13_3412 +0.5 1.7 2,3-dihydroxybiphenyl 1,2-dioxygenase (EC 1.13.11.39) compare
PfGW456L13_434 +0.5 2.5 Alpha-ketoglutarate-dependent taurine dioxygenase (EC 1.14.11.17) compare
PfGW456L13_5077 +0.5 2.6 Fructose repressor FruR, LacI family compare
PfGW456L13_1710 +0.5 2.8 Ribosomal RNA large subunit methyltransferase F (EC 2.1.1.51) compare
PfGW456L13_2147 +0.5 1.3 hypothetical protein compare
PfGW456L13_3437 +0.5 2.0 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase (EC 4.1.1.45) compare
PfGW456L13_2991 +0.5 2.7 hypothetical protein compare
PfGW456L13_4022 +0.5 1.4 FIG00953243: hypothetical protein compare
PfGW456L13_3386 +0.5 1.9 Glutathione peroxidase family protein compare
PfGW456L13_3874 +0.5 1.7 Transcriptional regulator, TetR family compare
PfGW456L13_3583 +0.5 1.8 4-hydroxyproline epimerase (EC 5.1.1.8) compare
PfGW456L13_4066 +0.5 2.0 Putative analog of CcoH, COG3198 compare
PfGW456L13_4255 +0.5 2.0 FIG00964480: hypothetical protein compare
PfGW456L13_4709 +0.5 1.6 hypothetical protein compare
PfGW456L13_500 +0.5 1.5 FIG00954152: hypothetical protein compare
PfGW456L13_3487 +0.4 1.5 hypothetical protein compare
PfGW456L13_2760 +0.4 1.3 hypothetical protein compare
PfGW456L13_1932 +0.4 2.1 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
PfGW456L13_2780 +0.4 0.8 hypothetical protein compare
PfGW456L13_191 +0.4 2.5 Ethidium bromide-methyl viologen resistance protein EmrE compare
PfGW456L13_1432 +0.4 2.9 FIG00960037: hypothetical protein compare
PfGW456L13_4179 +0.4 1.9 5-Hydroxyisourate Hydrolase (HIUase) (EC 3.5.2.17) compare
PfGW456L13_4317 +0.4 2.8 hypothetical protein compare
PfGW456L13_2239 +0.4 1.5 hypothetical protein compare
PfGW456L13_1864 +0.4 2.0 FIG023103: Predicted transmembrane protein compare
PfGW456L13_4122 +0.4 2.5 FIG002781: Alpha-L-glutamate ligase family protein compare
PfGW456L13_1793 +0.4 2.0 Glycine cleavage system transcriptional activator compare
PfGW456L13_922 +0.4 1.2 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
PfGW456L13_253 +0.4 1.9 FIG138576: 3-oxoacyl-[ACP] synthase (EC 2.3.1.41) compare
PfGW456L13_3393 +0.4 1.2 FIG00481831: hypothetical protein compare
PfGW456L13_3830 +0.4 1.0 FIG00955248: hypothetical protein compare
PfGW456L13_1374 +0.4 1.6 FIG00954871: hypothetical protein compare
PfGW456L13_4884 +0.4 0.8 hypothetical protein compare
PfGW456L13_4981 +0.4 1.3 Type III effector HopPmaJ compare
PfGW456L13_1223 +0.4 1.7 Lipoate-protein ligase A compare
PfGW456L13_4139 +0.4 1.1 hypothetical protein compare
PfGW456L13_3383 +0.4 1.5 hypothetical protein compare
PfGW456L13_2918 +0.4 1.3 FIG00954920: hypothetical protein compare
PfGW456L13_1673 +0.4 1.9 Permeases of the drug/metabolite transporter (DMT) superfamily compare
PfGW456L13_4495 +0.4 2.1 Protein YcgL compare
PfGW456L13_2717 +0.4 0.6 hypothetical protein compare
PfGW456L13_824 +0.4 1.8 Chromosome segregation ATPases compare
PfGW456L13_3610 +0.4 0.7 3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100) compare
PfGW456L13_4031 +0.4 1.0 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
PfGW456L13_3744 +0.4 1.6 Ethanolamine permease compare
PfGW456L13_2305 +0.4 1.8 ABC transporter in pyoverdin gene cluster, ATP-binding component compare
PfGW456L13_4065 +0.4 2.3 Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation compare
PfGW456L13_3941 +0.4 2.5 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
PfGW456L13_3362 +0.4 1.9 Transporter, LysE family compare
PfGW456L13_3968 +0.4 0.7 hypothetical protein compare
PfGW456L13_6 +0.4 1.1 FIG000605: protein co-occurring with transport systems (COG1739) compare
PfGW456L13_4918 +0.4 2.2 FIG00959654: hypothetical protein compare
PfGW456L13_1752 +0.4 1.4 Leucyl-tRNA synthetase compare
PfGW456L13_2603 +0.4 0.9 Transcriptional regulator, MarR family compare
PfGW456L13_4540 +0.4 2.5 Trans-aconitate 2-methyltransferase (EC 2.1.1.144) compare
PfGW456L13_2547 +0.4 1.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
PfGW456L13_2845 +0.4 0.8 FIG00953703: hypothetical protein compare
PfGW456L13_3411 +0.4 1.2 Fumarylacetoacetate hydrolase family protein compare
PfGW456L13_2229 +0.4 2.6 Universal stress protein family compare
PfGW456L13_4545 +0.4 0.7 Integral membrane protein compare
PfGW456L13_4043 +0.4 1.6 Universal stress protein family COG0589 compare
PfGW456L13_89 +0.4 1.8 Tabtoxin resistance protein compare
PfGW456L13_2073 +0.4 0.9 hypothetical protein compare
PfGW456L13_3074 +0.4 2.0 lipoprotein, putative compare
PfGW456L13_2723 +0.4 1.2 hypothetical protein compare
PfGW456L13_2923 +0.4 2.1 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) compare
PfGW456L13_3107 +0.4 1.3 Type I restriction-modification system, specificity subunit S (EC 3.1.21.3) compare
PfGW456L13_5118 +0.4 2.5 D-lactate dehydrogenase (quinone), FeS subunit (EC 1.1.5.12) (from data) compare
PfGW456L13_1726 +0.4 1.7 FIG00953680: hypothetical protein compare
PfGW456L13_4391 +0.4 2.1 Periplasmic nitrate reductase component NapD compare
PfGW456L13_2672 +0.4 1.6 Isochorismatase (EC 3.3.2.1) compare
PfGW456L13_1482 +0.4 1.6 type 4 fimbrial biogenesis protein FimU compare
PfGW456L13_3671 +0.4 0.6 hypothetical protein compare
PfGW456L13_4477 +0.4 1.4 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
PfGW456L13_303 +0.4 1.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PfGW456L13_4911 +0.4 1.7 Transcriptional regulator, LysR family compare
PfGW456L13_1359 +0.4 1.5 LSU m3Psi1915 methyltransferase RlmH compare
PfGW456L13_262 +0.4 1.3 hypothetical protein compare
PfGW456L13_5117 +0.4 1.5 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
PfGW456L13_2333 +0.4 2.2 Glycosyltransferase (EC 2.4.1.-) compare
PfGW456L13_1356 +0.4 1.3 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) compare
PfGW456L13_3604 +0.4 1.5 Aldehyde dehydrogenase (EC 1.2.1.3) compare
PfGW456L13_1125 +0.4 2.4 Acyltransferase family protein compare
PfGW456L13_3306 +0.4 1.7 hypothetical protein compare
PfGW456L13_2866 +0.4 1.5 Transcriptional regulator, IclR family compare
PfGW456L13_1829 +0.4 1.1 glycosyl transferase, group 1 family protein compare
PfGW456L13_2447 +0.4 1.1 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
PfGW456L13_3033 +0.4 1.3 FIG00962118: hypothetical protein compare
PfGW456L13_3092 +0.4 2.1 Formate dehydrogenase O beta subunit (EC 1.2.1.2) compare
PfGW456L13_3125 +0.4 1.4 Glutathione-dependent formaldehyde-activating enzyme (EC 4.4.1.22) compare
PfGW456L13_2150 +0.4 1.2 Carbon storage regulator compare
PfGW456L13_3557 +0.4 1.2 Nitrate/nitrite response regulator protein compare
PfGW456L13_1758 +0.4 2.6 Electron transport complex protein RnfA compare
PfGW456L13_2510 +0.4 2.0 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit compare
PfGW456L13_1688 +0.4 2.6 Predicted ATPase related to phosphate starvation-inducible protein PhoH compare
PfGW456L13_5105 +0.4 1.1 hypothetical protein compare
PfGW456L13_3562 +0.4 2.1 Permeases of the major facilitator superfamily compare
PfGW456L13_2762 +0.4 1.7 Carbon storage regulator compare
PfGW456L13_2933 +0.4 0.9 LysR family transcriptional regulator STM2281 compare
PfGW456L13_4627 +0.3 1.3 FIG00953505: hypothetical protein compare
PfGW456L13_2143 +0.3 1.4 Translation initiation factor 2 (IF-2; GTPase) compare
PfGW456L13_1947 +0.3 1.6 CTP synthase (EC 6.3.4.2) compare
PfGW456L13_320 +0.3 1.6 Histidine ammonia-lyase (EC 4.3.1.3) (from data) compare
PfGW456L13_2813 +0.3 1.1 Adenylylsulfate reductase beta-subunit (EC 1.8.99.2) compare
PfGW456L13_351 +0.3 0.9 Glutaredoxin 3 (Grx3) compare
PfGW456L13_2352 +0.3 1.0 N-carbamoyl-L-amino acid hydrolase (EC 3.5.1.87) compare
PfGW456L13_4154 +0.3 1.3 FIG00957412: hypothetical protein compare
PfGW456L13_4953 +0.3 1.8 Glycine cleavage system transcriptional activator compare
PfGW456L13_3869 +0.3 2.1 Disease resistance protein / Tetratricopeptide repeat-containing protein compare
PfGW456L13_2511 +0.3 0.9 short-chain dehydrogenase/reductase SDR compare
PfGW456L13_3574 +0.3 1.4 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
PfGW456L13_1043 +0.3 1.8 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) compare
PfGW456L13_4064 +0.3 1.0 Cytochrome c oxidase subunit CcoP (EC 1.9.3.1) compare
PfGW456L13_4865 +0.3 1.2 Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) compare
PfGW456L13_1433 +0.3 1.5 DJ-1/YajL/PfpI superfamily, includes chaperone protein YajL (former ThiJ), parkinsonism-associated protein DJ-1, peptidases PfpI, Hsp31 compare
PfGW456L13_356 +0.3 1.8 Putative periplasmic protein YibQ, distant homology with nucleoside diphosphatase and polysaccharide deacetylase compare
PfGW456L13_810 +0.3 1.5 FIG00954130: hypothetical protein compare
PfGW456L13_4941 +0.3 2.3 Protein export cytoplasm protein SecA ATPase RNA helicase (TC 3.A.5.1.1) compare
PfGW456L13_3537 +0.3 1.1 Transcriptional regulator, ArsR family compare
PfGW456L13_2787 +0.3 1.9 Phage major tail tube protein compare
PfGW456L13_1722 +0.3 2.3 Thiol:disulfide interchange protein DsbC compare
PfGW456L13_2002 +0.3 1.6 Flagellar basal-body rod protein FlgC compare
PfGW456L13_3585 +0.3 0.7 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) compare
PfGW456L13_419 +0.3 1.7 hypothetical protein compare
PfGW456L13_1918 +0.3 1.0 ABC-type phosphate/phosphonate transport system, periplasmic component compare
PfGW456L13_454 +0.3 1.0 Methionine ABC transporter permease protein compare
PfGW456L13_554 +0.3 2.3 Glutaryl-CoA dehydrogenase (EC 1.3.99.7) compare
PfGW456L13_789 +0.3 1.0 hypothetical protein compare
PfGW456L13_4493 +0.3 1.2 Nitroreductase family protein compare
PfGW456L13_1216 +0.3 1.6 Phosphoglycolate phosphatase (EC 3.1.3.18) compare
PfGW456L13_3052 +0.3 0.6 Response regulator compare
PfGW456L13_4427 +0.3 1.4 T1SS associated transglutaminase-like cysteine proteinase LapP compare
PfGW456L13_1788 +0.3 2.0 Transcriptional regulator PobR, AraC family compare
PfGW456L13_3375 +0.3 1.0 tRNA-(ms[2]io[6]A)-hydroxylase (EC 1.-.-.-) compare
PfGW456L13_121 +0.3 1.4 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
PfGW456L13_1827 +0.3 1.8 FIG00955324: hypothetical protein compare
PfGW456L13_4664 +0.3 1.4 Putative NADPH-quinone reductase (modulator of drug activity B) compare


Specific Phenotypes

For 1 genes in this experiment

For control Kanamycin sulfate in Pseudomonas fluorescens GW456-L13

For control Kanamycin sulfate across organisms