Experiment set7IT055 for Pseudomonas putida KT2440

Compare to:

L-Lysine 10 mM carbon source

200 most important genes:

  gene name fitness t score description  
PP_3597 -6.6 -4.6 L-lysine and D-lysine ABC transporter, ATPase component (from data) compare
PP_5260 -6.1 -8.3 2-oxoadipate decarboxylase/hydroxylase (2-hydroxyglutarate synthase) (from data) conserved
PP_3591 -5.7 -3.9 Delta 1-piperideine-2-carboxylate reductase compare
PP_4909 -5.4 -7.4 phosphoserine phosphatase compare
PP_3593 -5.0 -10.2 L-lysine and D-lysine ABC transporter, substrate-binding component (from data) compare
PP_0083 -5.0 -4.9 tryptophan synthase beta chain compare
PP_0293 -5.0 -3.1 Imidazole glycerol phosphate synthase subunit HisF compare
PP_4890 -4.8 -5.7 ATP phosphoribosyltransferase regulatory subunit compare
PP_4678 -4.8 -16.4 Ketol-acid reductoisomerase compare
PP_0290 -4.7 -9.1 Imidazole glycerol phosphate synthase subunit HisH compare
PP_3594 -4.7 -7.8 L-lysine and D-lysine ABC transporter, permease component 1 (from data) conserved
PP_5258 -4.6 -8.7 L-piperidine-6-carboxylate dehydrogenase conserved
PP_0292 -4.5 -4.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
PP_0289 -4.5 -9.2 Imidazoleglycerol-phosphate dehydratase compare
PP_2910 -4.4 -11.4 L-2-hydroxyglutarate oxidase compare
PP_3592 -4.4 -9.6 Transcriptional regulator, RpiR family compare
PP_0082 -4.3 -5.1 tryptophan synthase alpha chain compare
PP_0966 -4.1 -9.7 Histidinol dehydrogenase compare
PP_2001 -4.1 -9.1 O-succinylhomoserine sulfhydrylase compare
PP_3649 -4.0 -4.7 Transcriptional regulator, GntR family compare
PP_4679 -4.0 -7.4 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_2371 -4.0 -6.6 Sulphite reductase hemoprotein, beta subunit compare
PP_1988 -4.0 -8.3 3-isopropylmalate dehydrogenase compare
PP_5257 -4.0 -11.4 L-pipecolate oxidase conserved
PP_0422 -4.0 -6.5 Indole-3-glycerol phosphate synthase compare
PP_5097 -3.9 -12.0 homoserine O-acetyltransferase compare
PP_1995 -3.8 -8.6 N-(5'-phosphoribosyl)anthranilate isomerase compare
PP_3511 -3.8 -7.8 Branched-chain-amino-acid aminotransferase compare
PP_1088 -3.7 -11.2 Argininosuccinate synthase compare
PP_1215 -3.7 -2.3 Crossover junction endodeoxyribonuclease RuvC compare
PP_3924 -3.7 -5.4 conserved protein of unknown function compare
PP_5015 -3.7 -4.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
PP_0787 -3.6 -4.8 quinolinate phosphoribosyltransferase (decarboxylating) monomer compare
PP_0965 -3.5 -11.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
PP_0184 -3.5 -6.7 Argininosuccinate lyase compare
PP_0417 -3.5 -14.0 Anthranilate synthase component 1 compare
PP_3595 -3.5 -8.2 L-lysine and D-lysine ABC transporter, permease component 2 (from data) conserved
PP_5155 -3.4 -6.0 D-3-phosphoglycerate dehydrogenase / alpha-ketoglutarate reductase compare
PP_4482 -3.4 -4.6 Transcriptional regulator, AraC family compare
PP_1986 -3.4 -3.5 3-isopropylmalate dehydratase small subunit compare
PP_4695 -3.4 -13.9 Sensory box histidine kinase compare
PP_5098 -3.4 -7.5 methionine biosynthesis protein MetW compare
PP_4696 -3.4 -6.0 Nitrogen regulation protein NR(I) compare
PP_0691 -3.3 -2.3 Glutamate 5-kinase compare
PP_5014 -3.3 -4.0 Phosphoribosyl-AMP cyclohydrolase compare
PP_1985 -3.2 -4.1 3-isopropylmalate dehydratase large subunit compare
PP_0967 -3.2 -8.7 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
PP_0382 -3.2 -7.3 5-aminopentanamidase conserved
PP_4680 -3.2 -11.0 acetohydroxybutanoate synthase / acetolactate synthase compare
PP_5128 -3.2 -7.5 Dihydroxy-acid dehydratase compare
PP_3603 -3.1 -7.1 Transcriptional regulator, GntR family compare
PP_5185 -3.0 -6.1 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase compare
PP_1231 -3.0 -5.4 quinolinate synthase [4Fe-4S] cluster subunit compare
PP_3596 -3.0 -6.1 D-lysine oxidase compare
PP_4126 -2.9 -2.0 NADH-quinone oxidoreductase subunit I compare
PP_0949 -2.9 -9.3 putative ATP-binding protein UPF0042 compare
PP_3241 -2.8 -1.5 conserved exported protein of unknown function compare
PP_0356 -2.8 -5.7 malate synthase G compare
PP_4937 -2.8 -4.2 toluene tolerance protein compare
PP_0421 -2.7 -6.0 Anthranilate phosphoribosyltransferase compare
PP_2326 -2.7 -7.9 Universal stress protein compare
PP_4493 -2.7 -11.2 D-2-hydroxyglutarate dehydrogenase (EC 1.1.99.39) (from data) compare
PP_1654 -2.7 -4.4 cysteine synthase B compare
PP_0214 -2.7 -6.9 4-aminobutyrate aminotransferase compare
PP_3999 -2.7 -6.8 Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase compare
PP_5289 -2.6 -3.0 Acetylglutamate kinase compare
PP_4129 -2.6 -1.8 NADH:ubiquinone oxidoreductase, membrane subunit L compare
PP_2370 -2.6 -3.7 conserved protein of unknown function compare
PP_2168 -2.5 -7.8 Transaldolase compare
PP_1079 -2.5 -4.2 Ornithine carbamoyltransferase compare
PP_0213 -2.5 -7.0 succinate-semialdehyde dehydrogenase (NADP+) compare
PP_0383 -2.5 -7.6 Lysine 2-monooxygenase conserved
PP_0384 -2.5 -6.3 Transcriptional regulator, AsnC family conserved
PP_4829 -2.4 -4.0 putative precorrin-3B synthase compare
PP_0127 -2.3 -4.3 Thiol:disulfide interchange protein compare
PP_2868 -2.2 -4.9 Transcriptional regulator, Cro/CI family compare
PP_4131 -2.2 -5.2 NADH-quinone oxidoreductase subunit N compare
PP_4116 -2.2 -8.3 isocitrate lyase compare
PP_1673 -2.1 -4.9 cobyrinate a,c-diamide synthase compare
PP_4364 -2.1 -3.7 putative Anti-sigma F factor antagonist compare
PP_1941 -2.0 -6.5 conserved protein of unknown function compare
PP_5216 -2.0 -2.0 exopolyphosphatase compare
PP_4910 -2.0 -1.9 conserved protein of unknown function compare
PP_1344 -2.0 -2.4 conserved protein of unknown function compare
PP_1319 -2.0 -5.8 Ubiquinol--cytochrome c reductase, cytochrome c1 compare
PP_4121 -2.0 -4.3 NADH-quinone oxidoreductase subunit C/D compare
PP_4120 -2.0 -2.6 NADH-quinone oxidoreductase subunit B compare
PP_4693 -1.9 -5.5 RNA polymerase-binding transcription factor DksA compare
PP_4124 -1.9 -3.1 NADH-quinone oxidoreductase subunit G compare
PP_4724 -1.9 -4.0 Carbamoyl-phosphate synthase small chain compare
PP_4122 -1.8 -1.2 proton-pumping NADH:ubiquinone oxidoreductase, respiratory complex I, subunit E compare
PP_4723 -1.8 -8.1 Carbamoyl-phosphate synthase large chain compare
PP_4699 -1.8 -4.0 3-methyl-2-oxobutanoate hydroxymethyltransferase compare
PP_4793 -1.8 -1.4 conserved protein of unknown function compare
PP_4832 -1.7 -3.0 Precorrin-6x reductase compare
PP_1236 -1.7 -5.7 putative Glycine cleavage system transcriptional repressor compare
PP_5253 -1.7 -3.7 Arylesterase compare
PP_2327 -1.7 -4.1 transcriptional dual regulator / CysB-O-acetyl-L-serine compare
PP_3938 -1.7 -2.3 conserved protein of unknown function compare
PP_0126 -1.7 -3.5 Cytochrome c4 compare
PP_1734 -1.7 -2.5 Probable septum site-determining protein MinC compare
PP_0880 -1.7 -3.9 dipeptide ABC transporter - putative membrane subunit compare
PP_5095 -1.7 -1.1 pyrroline-5-carboxylate reductase compare
PP_1318 -1.6 -5.5 Cytochrome b compare
PP_1428 -1.6 -2.1 Sigma factor AlgU negative regulatory protein compare
PP_4130 -1.6 -3.6 NADH:ubiquinone oxidoreductase, membrane subunit M compare
PP_5085 -1.6 -4.8 malic enzyme B compare
PP_4961 -1.5 -1.5 putative Lipoprotein compare
PP_3506 -1.5 -2.3 Magnesium chelatase, subunit ChII compare
PP_5198 -1.5 -2.1 conserved protein of unknown function compare
PP_1733 -1.5 -2.4 membrane ATPase of the MinC-MinD-MinE system compare
PP_1598 -1.5 -3.9 regulatory intramembrane protein RIP zinc protease compare
PP_1664 -1.5 -2.6 phosphoribosylglycinamide formyltransferase 1 compare
PP_4576 -1.5 -6.2 allophanate hydrolase subunit compare
PP_1681 -1.5 -7.3 cobalamin 5'-phosphate synthase / Cobalamin synthase compare
PP_0833 -1.5 -1.7 queuine tRNA-ribosyltransferase compare
PP_1860 -1.5 -5.5 Organic hydroperoxide resistance transcriptional regulator compare
PP_0420 -1.5 -4.7 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex compare
PP_1679 -1.5 -1.7 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
PP_4828 -1.5 -1.5 Precorrin-8X methylmutase compare
PP_4575 -1.4 -3.3 Urea amidolyase-related protein compare
PP_2375 -1.4 -7.9 cobalamin-dependent methionine synthase compare
PP_0593 -1.4 -1.1 putative ribosome-binding factor compare
PP_4827 -1.4 -6.1 Precorrin-2 C(20)-methyltransferase compare
PP_2302 -1.4 -3.9 DNA-binding, ATP-dependent protease compare
PP_2499 -1.4 -1.6 conserved protein of unknown function compare
PP_4700 -1.4 -1.3 pantothenate synthetase compare
PP_4943 -1.4 -2.2 putative Glycosyl transferase compare
PP_4830 -1.4 -3.5 precorrin-6Y C(5,15)-methyltransferase compare
PP_5177 -1.4 -3.7 spermidine/putrescine ABC transporter - permease subunit compare
PP_4261 -1.3 -4.1 cation-transporting P-type ATPase compare
PP_1025 -1.3 -5.5 2-isopropylmalate synthase compare
PP_1317 -1.3 -4.1 Ubiquinol-cytochrome c reductase iron-sulfur subunit compare
PP_1677 -1.3 -4.7 Adenosyl-cobyric acid synthase compare
PP_1493 -1.3 -2.5 chemotaxis response regulator protein-glutamate methylesterase of group 3 operon compare
PP_0719 -1.3 -0.9 ribosome-associated potassium-dependent informational ATP/GTPase compare
PP_0881 -1.3 -3.1 dipeptide ABC transporter - putative membrane subunit compare
PP_5274 -1.2 -1.3 conserved protein of unknown function compare
PP_4977 -1.2 -5.9 5,10-methylenetetrahydrofolate reductase compare
PP_4108 -1.2 -3.7 2-aminoadipate transaminase (EC 2.6.1.39) (from data) compare
PP_5146 -1.2 -6.2 RNA pyrophosphohydrolase compare
PP_1672 -1.2 -3.5 cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase compare
PP_5181 -1.2 -6.9 spermidine/putrescine ABC transporter - periplasmic subunit conserved
PP_3507 -1.2 -6.9 Aerobic cobaltochelatase subunit CobN compare
PP_3409 -1.2 -1.9 putative Cobalamin biosynthesis protein cobE compare
PP_3508 -1.2 -2.2 Protein CobW compare
PP_t12 -1.2 -1.1 tRNA-Thr compare
PP_1297 -1.2 -3.7 putative amino-acid ABC transporter-binding protein YhdW compare
PP_0855 -1.2 -2.2 conserved protein of unknown function compare
PP_0291 -1.2 -1.3 conserved protein of unknown function compare
PP_4826 -1.2 -3.6 Precorrin-3B C17-methyltransferase compare
PP_5028 -1.2 -2.7 proline iminopeptidase compare
PP_2820 -1.2 -2.1 HTH-type transcriptional regulator nfxB compare
PP_4263 -1.2 -2.0 putative membrane-bounded cytochrome biogenesis cycZ-like domain, copper tolerance protein compare
PP_1764 -1.1 -4.2 Phosphoglycolate phosphatase 2 compare
PP_0413 -1.1 -6.5 Polyamine ABC transporter, permease protein compare
PP_2806 -1.1 -3.2 Transcriptional regulator, TetR family compare
PP_3755 -1.1 -3.5 3-hydroxybutyryl-CoA dehydrogenase compare
PP_4577 -1.1 -3.5 UPF0271 protein PP_4577 compare
PP_2633 -1.1 -1.3 conserved protein of unknown function compare
PP_4989 -1.1 -2.7 Protein PilJ compare
PP_2889 -1.1 -3.5 putative Transmembrane regulator PrtR compare
PP_0995 -1.1 -5.3 conserved membrane protein of unknown function compare
PP_1739 -1.1 -3.0 conserved membrane protein of unknown function compare
PP_0313 -1.1 -1.5 putative electron transfer flavoprotein beta subunit compare
PP_5639 -1.1 -4.1 conserved exported protein of unknown function compare
PP_0345 -1.1 -2.7 putative Heptose kinase WapP compare
PP_3484 -1.1 -3.0 Response regulator receiver protein compare
PP_1233 -1.1 -2.8 sulfurtransferase compare
PP_0232 -1.0 -1.2 ATP-binding taurine transporter subunit compare
PP_5582 -1.0 -1.5 conserved protein of unknown function compare
PP_5179 -1.0 -4.6 spermidine/putrescine ABC transporter - ATP binding subunit compare
PP_1758 -1.0 -3.6 putative sulfurtransferase containing rhodanese-like domain compare
PP_5600 -1.0 -1.9 conserved protein of unknown function compare
PP_0758 -1.0 -2.7 conserved protein of unknown function compare
PP_1208 -1.0 -1.9 conserved protein of unknown function, SlyX family compare
PP_2337 -1.0 -1.8 aconitate isomerase compare
PP_4593 -1.0 -1.0 conserved protein of unknown function compare
PP_3065 -1.0 -3.5 Pyocin R2_PP, tail formation compare
PP_0774 -1.0 -3.2 Phosphate acetyltransferase compare
PP_0414 -1.0 -2.5 Polyamine ABC transporter, permease protein compare
PP_0435 -1.0 -6.5 Peptidase, M23/M37 family compare
PP_1377 -1.0 -3.9 beta-ketoadipyl-CoA thiolase compare
PP_1675 -1.0 -3.9 Subunit of adenosylcobinamide-phosphate synthase beta component compare
PP_2110 -1.0 -2.9 putative ribosomal large subunit pseudouridine synthase compare
PP_1736 -0.9 -2.3 conserved protein of unknown function compare
PP_4058 -0.9 -4.2 1,4-alpha-glucan branching enzyme compare
PP_1048 -0.9 -1.7 putative protein secretion protein for export compare
PP_5094 -0.9 -1.3 putative enzyme with PLP binding domain compare
PP_4707 -0.9 -2.3 OsmY-related protein compare
PP_1026 -0.9 -1.4 Peptidase, M23/M37 family compare
PP_1300 -0.9 -2.9 putative amino acid ABC transporter - ATP-binding subunit compare
PP_2908 -0.9 -2.4 DNA-binding transcriptional repressor compare
PP_0311 -0.9 -3.7 putative dimethylglycine dehydrogenase subunit compare
PP_2931 -0.9 -2.5 conserved protein of unknown function compare
PP_4247 -0.9 -1.3 Exonuclease compare
PP_0878 -0.9 -4.1 dipeptide ABC transporter, binding subunit compare
PP_3541 -0.9 -1.6 Transporter, MgtC family compare
PP_5184 -0.9 -3.4 glutamylpolyamine synthetase compare
PP_4256 -0.9 -3.1 cytochrome c oxidase subunit, cbb3-type compare


Specific Phenotypes

For 24 genes in this experiment

For carbon source L-Lysine in Pseudomonas putida KT2440

For carbon source L-Lysine across organisms