Experiment set76S739 for Escherichia coli BW25113

Compare to:

NoPhageControl|T7phage

200 most important genes:

  gene name fitness t score description  
b0222 lpcA -4.1 -2.8 phosphoheptose isomerase (NCBI) compare
b3052 rfaE -3.7 -3.6 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b2528 iscA -3.4 -2.4 iron-sulfur cluster assembly protein (NCBI) compare
b0741 pal -3.1 -3.7 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3860 dsbA -3.1 -11.8 periplasmic protein disulfide isomerase I (NCBI) compare
b0683 fur -3.0 -2.0 ferric uptake regulator (NCBI) compare
b0737 tolQ -3.0 -2.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3620 rfaF -3.0 -4.0 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3621 rfaC -2.9 -2.0 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b3390 aroK -2.8 -2.7 shikimate kinase I (NCBI) compare
b1936 intG -2.8 -1.9 predicted defective phage integrase (pseudogene) (RefSeq) compare
b3839 tatC -2.7 -7.3 TatABCE protein translocation system subunit (NCBI) compare
b0049 apaH -2.7 -1.8 diadenosinetetraphosphatase (NCBI) compare
b2318 truA -2.7 -3.6 tRNA pseudouridine synthase A (NCBI) compare
b0740 tolB -2.7 -2.6 translocation protein TolB precursor (NCBI) compare
b4593 ymgI -2.6 -1.8 hypothetical protein (RefSeq) compare
b2285 nuoE -2.6 -3.5 NADH dehydrogenase subunit E (NCBI) compare
b0739 tolA -2.6 -1.8 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2906 visC -2.5 -7.9 hypothetical protein (NCBI) compare
b3619 rfaD -2.5 -1.7 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b2284 nuoF -2.5 -5.9 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b4171 miaA -2.4 -3.6 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b2504 yfgG -2.4 -1.6 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b3935 priA -2.3 -3.4 primosome assembly protein PriA (NCBI) compare
b1185 dsbB -2.3 -2.9 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b2330 yfcB -2.2 -2.6 putative adenine-specific methylase (VIMSS) compare
b0142 folK -2.1 -0.9 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b2277 nuoM -2.1 -6.6 NADH dehydrogenase subunit M (NCBI) compare
b2830 nudH -2.1 -1.4 dinucleoside polyphosphate hydrolase (NCBI) compare
b4041 plsB -2.0 -2.1 glycerol-3-phosphate acyltransferase (VIMSS) compare
b2288 nuoA -2.0 -4.2 NADH dehydrogenase I chain A (VIMSS) compare
b1863 ruvC -2.0 -1.3 Holliday junction resolvase (NCBI) compare
b2283 nuoG -2.0 -7.2 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b1855 lpxM -1.9 -3.7 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b1291 sapD -1.9 -1.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2286 nuoC -1.9 -5.0 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b0726 sucA -1.8 -4.3 alpha-ketoglutarate decarboxylase (NCBI) compare
b0738 tolR -1.8 -1.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3778 rep -1.8 -7.8 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b1860 ruvB -1.8 -1.2 Holliday junction DNA helicase B (NCBI) compare
b3169 nusA -1.8 -2.2 transcription elongation factor NusA (NCBI) compare
b1192 ldcA -1.8 -3.5 L,D-carboxypeptidase A (NCBI) compare
b2276 nuoN -1.7 -5.6 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3613 yibP -1.7 -1.6 putative membrane protein (VIMSS) compare
b0439 lon -1.7 -5.1 DNA-binding ATP-dependent protease La (NCBI) compare
b2282 nuoH -1.7 -3.7 NADH dehydrogenase subunit H (NCBI) compare
b0018 mokC -1.7 -2.0 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b3816 corA -1.7 -7.1 magnesium/nickel/cobalt transporter (NCBI) compare
b3792 wzxE -1.7 -6.3 O-antigen translocase (NCBI) compare
b0232 yafN -1.6 -0.9 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b2576 srmB -1.6 -3.5 ATP-dependent RNA helicase (NCBI) compare
b2278 nuoL -1.6 -8.1 NADH dehydrogenase subunit L (NCBI) compare
b4042 dgkA -1.6 -1.6 diacylglycerol kinase (NCBI) compare
b1758 b1758 -1.6 -1.9 putative cytochrome oxidase (VIMSS) compare
b3838 tatB -1.6 -5.7 sec-independent translocase (NCBI) compare
b2281 nuoI -1.6 -2.9 NADH dehydrogenase subunit I (NCBI) compare
b0386 proC -1.5 -3.8 pyrroline-5-carboxylate reductase (NCBI) compare
b0890 ftsK -1.5 -1.0 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2287 nuoB -1.5 -3.5 NADH dehydrogenase subunit B (NCBI) compare
b1252 tonB -1.5 -3.0 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b3761 trpT -1.5 -1.8 tRNA-Trp (NCBI) compare
b3844 fre -1.4 -4.4 NAD(P)H-flavin reductase (NCBI) compare
b0051 ksgA -1.4 -4.0 dimethyladenosine transferase (NCBI) compare
b4146 yjeK -1.4 -1.4 predicted lysine aminomutase (NCBI) compare
b3183 obgE -1.4 -1.3 GTPase involved in cell partioning and DNA repair (NCBI) compare
b1290 sapF -1.4 -1.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0729 sucD -1.4 -2.5 succinyl-CoA synthetase subunit alpha (NCBI) compare
b3405 ompR -1.4 -3.7 osmolarity response regulator (NCBI) compare
b0200 gmhB -1.4 -0.9 hypothetical protein (NCBI) compare
b4053 alr -1.4 -6.0 alanine racemase (NCBI) compare
b2620 smpB -1.3 -1.2 SsrA-binding protein (NCBI) compare
b3426 glpD -1.3 -2.0 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b2947 gshB -1.3 -2.5 glutathione synthetase (NCBI) compare
b2688 gshA -1.3 -5.3 glutamate--cysteine ligase (NCBI) compare
b3204 ptsN -1.3 -3.9 sugar-specific enzyme IIA component of PTS (NCBI) compare
b0688 pgm -1.3 -2.8 phosphoglucomutase (NCBI) compare
b4202 rpsR -1.3 -1.6 30S ribosomal protein S18 (NCBI) compare
b1286 rnb -1.2 -1.8 exoribonuclease II (NCBI) compare
b4375 prfC -1.2 -4.0 peptide chain release factor 3 (NCBI) compare
b4179 vacB -1.2 -5.3 putative enzyme (VIMSS) compare
b4655 ythA -1.2 -1.7 expressed protein (RefSeq) compare
b3630 rfaP -1.2 -6.7 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3414 gntY -1.2 -3.6 predicted gluconate transport associated protein (NCBI) compare
b2340 sixA -1.2 -3.8 phosphohistidine phosphatase (NCBI) compare
b3916 pfkA -1.2 -2.0 6-phosphofructokinase (NCBI) compare
b1480 sra -1.2 -1.9 30S ribosomal subunit protein S22 (NCBI) compare
b2280 nuoJ -1.2 -3.5 NADH dehydrogenase subunit J (NCBI) compare
b0724 sdhB -1.2 -4.0 succinate dehydrogenase, FeS subunit (NCBI) compare
b4178 yjeB -1.2 -3.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b0438 clpX -1.2 -4.6 ATP-dependent protease ATP-binding subunit (NCBI) compare
b4158 yjeO -1.1 -3.5 conserved inner membrane protein (NCBI) compare
b1161 ycgX -1.1 -1.0 hypothetical protein (NCBI) compare
b0015 dnaJ -1.1 -5.2 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b3493 pitA -1.1 -4.7 phosphate transporter, low-affinity (NCBI) compare
b2017 yefM -1.1 -1.8 orf, hypothetical protein (VIMSS) compare
b3631 rfaG -1.1 -7.9 glucosyltransferase I (NCBI) compare
b1231 tyrT -1.1 -1.1 tRNA-Tyr (NCBI) compare
b0145 dksA -1.1 -2.2 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2248 yfaX -1.0 -2.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b0428 cyoE -1.0 -5.3 protoheme IX farnesyltransferase (NCBI) compare
b1861 ruvA -1.0 -0.7 Holliday junction DNA helicase motor protein (NCBI) compare
b3500 gor -1.0 -1.5 glutathione reductase (NCBI) compare
b4201 priB -1.0 -2.2 primosomal replication protein N (NCBI) compare
b1257 yciE -1.0 -0.6 hypothetical protein (NCBI) compare
b1293 sapB -1.0 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1613 manA -1.0 -2.0 mannose-6-phosphate isomerase (VIMSS) compare
b2279 nuoK -1.0 -1.8 NADH dehydrogenase subunit K (NCBI) compare
b3741 gidA -1.0 -1.7 glucose-inhibited division protein A (NCBI) compare
b3281 aroE -1.0 -6.9 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b3706 trmE -1.0 -2.7 tRNA modification GTPase (NCBI) compare
b2531 iscR -1.0 -1.4 DNA-binding transcriptional repressor (NCBI) compare
b2808 gcvA -1.0 -2.3 DNA-binding transcriptional dual regulator (NCBI) compare
b3791 rffA -1.0 -3.6 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1084 rne -1.0 -4.5 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b3389 aroB -1.0 -5.1 3-dehydroquinate synthase (NCBI) compare
b4503 yafF -1.0 -0.9 no description compare
b3836 b3836 -1.0 -2.9 orf, hypothetical protein (VIMSS) compare
b0431 cyoB -0.9 -6.4 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b2188 yejM -0.9 -5.4 predicted hydrolase, inner membrane (NCBI) compare
b0053 surA -0.9 -3.1 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2935 tktA -0.9 -0.9 transketolase 1, thiamin-binding (NCBI) compare
b2175 spr -0.9 -2.9 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b0167 glnD -0.9 -3.2 PII uridylyl-transferase (NCBI) compare
b4596 yciZ -0.9 -1.2 hypothetical protein (RefSeq) compare
b2189 proL -0.9 -1.6 tRNA-Pro (NCBI) compare
b1677 lpp -0.9 -1.8 murein lipoprotein (NCBI) compare
b0720 gltA -0.9 -3.4 citrate synthase (NCBI) compare
b1109 ndh -0.9 -2.1 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b1429 tehA -0.9 -1.1 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1330 ynaI -0.9 -3.1 conserved inner membrane protein (NCBI) compare
b0721 sdhC -0.9 -3.6 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b0429 cyoD -0.9 -3.8 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b0437 clpP -0.9 -2.9 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b0723 sdhA -0.9 -6.1 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b4538 yoeF -0.9 -1.5 hypothetical protein (RefSeq) compare
b1951 rcsA -0.9 -1.0 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b1269 rluB -0.9 -2.6 23S rRNA pseudouridylate synthase (NCBI) compare
b3236 mdh -0.9 -4.4 malate dehydrogenase (NCBI) compare
b2699 recA -0.9 -0.8 recombinase A (NCBI) compare
b3889 yiiE -0.9 -1.6 predicted transcriptional regulator (RefSeq) compare
b3387 dam -0.8 -5.4 DNA adenine methylase (NCBI) compare
b1299 puuR -0.8 -3.3 DNA-binding transcriptional repressor (NCBI) compare
b3629 rfaS -0.8 -2.6 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1236 galU -0.8 -2.9 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1292 sapC -0.8 -1.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2168 fruK -0.8 -0.9 1-phosphofructokinase (NCBI) compare
b2476 purC -0.8 -2.0 phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) compare
b1506 yneL -0.8 -1.3 predicted transcriptional regulator (NCBI) compare
b3164 pnp -0.8 -1.7 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b2822 recC -0.8 -1.9 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4414 tff -0.8 -1.7 unknown RNA (NCBI) compare
b2904 gcvH -0.8 -1.4 glycine cleavage system protein H (NCBI) compare
b3398 yrfF -0.8 -2.0 predicted inner membrane protein (NCBI) compare
b0677 nagA -0.8 -3.1 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b0632 dacA -0.8 -4.0 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b3875 ompL -0.8 -1.6 predicted outer membrane porin L (NCBI) compare
b1502 ydeQ -0.8 -1.7 predicted fimbrial-like adhesin protein (NCBI) compare
b1175 minD -0.8 -2.9 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b0430 cyoC -0.8 -2.4 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b1058 yceO -0.8 -0.4 hypothetical protein (NCBI) compare
b4139 aspA -0.8 -4.7 aspartate ammonia-lyase (aspartase) (VIMSS) compare
b2684 mprA -0.8 -2.4 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux (NCBI) compare
b4195 ulaC -0.8 -1.9 L-ascorbate-specific enzyme IIA component of PTS (NCBI) compare
b1690 ydiM -0.8 -1.1 predicted transporter (NCBI) compare
b3728 pstS -0.8 -1.6 phosphate transporter subunit (NCBI) compare
b0125 hpt -0.8 -2.8 hypoxanthine phosphoribosyltransferase (VIMSS) compare
b4181 yjfI -0.8 -2.3 hypothetical protein (NCBI) compare
b1235 rssB -0.8 -3.2 response regulator of RpoS (NCBI) compare
b4410 ecnA -0.8 -1.1 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b0953 rmf -0.8 -1.7 ribosome modulation factor (NCBI) compare
b3933 ftsN -0.8 -4.9 essential cell division protein (NCBI) compare
b3107 yhaL -0.8 -1.0 orf, hypothetical protein (VIMSS) compare
b1558 cspF -0.8 -2.2 Qin prophage; cold shock protein (NCBI) compare
b3811 xerC -0.8 -0.7 site-specific tyrosine recombinase XerC (NCBI) compare
b0082 mraW -0.7 -1.8 S-adenosyl-methyltransferase (NCBI) compare
b4481 rffT -0.7 -3.1 4-alpha-L-fucosyltransferase (NCBI) compare
b2398 yfeC -0.7 -3.2 orf, hypothetical protein (VIMSS) compare
b1351 racC -0.7 -0.5 Rac prophage; predicted protein (NCBI) compare
b4648 ysaC -0.7 -2.4 no description compare
b4313 fimE -0.7 -4.6 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b2814 metZ -0.7 -1.1 tRNA-Met (NCBI) compare
b3035 tolC -0.7 -3.9 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b3863 polA -0.7 -0.7 DNA polymerase I (NCBI) compare
b1847 yebF -0.7 -1.1 predicted protein (RefSeq) compare
b4640 yoeG -0.7 -1.6 no description compare
b1153 ymfQ -0.7 -1.5 e14 prophage; conserved protein (NCBI) compare
b1103 ycfF -0.7 -0.7 orf, hypothetical protein (VIMSS) compare
b2314 dedD -0.7 -2.2 putative lipoprotein (VIMSS) compare
b0432 cyoA -0.7 -4.6 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b2080 b2080 -0.7 -1.5 orf, hypothetical protein (VIMSS) compare
b0908 aroA -0.7 -3.2 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b1205 ychH -0.7 -1.2 predicted inner membrane protein (NCBI) compare
b0247 ykfG -0.7 -1.1 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b4191 ulaR -0.7 -1.7 DNA-binding transcriptional dual regulator (NCBI) compare
b2501 ppk -0.7 -3.6 polyphosphate kinase (NCBI) compare
b3229 sspA -0.7 -1.7 stringent starvation protein A (NCBI) compare
b0957 ompA -0.7 -2.4 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b4418 sraB -0.7 -1.3 unknown RNA (NCBI) compare
b2111 yehD -0.7 -1.9 predicted fimbrial-like adhesin protein (NCBI) compare
b1536 ydeI -0.7 -0.4 hypothetical protein (NCBI) compare


Specific Phenotypes

For 2 genes in this experiment

For no-phage No-Phage in Escherichia coli BW25113

For no-phage No-Phage across organisms