Experiment set76S714 for Escherichia coli BW25113

Compare to:

NoPhageControl|T7phage

200 most detrimental genes:

  gene name fitness t score description  
b3341 rpsG +2.0 3.2 30S ribosomal protein S7 (NCBI) compare
b4402 yjjY +1.9 1.4 hypothetical protein (NCBI) compare
b2741 rpoS +1.6 7.9 RNA polymerase sigma factor (NCBI) compare
b0014 dnaK +1.5 2.6 molecular chaperone DnaK (NCBI) compare
b1642 slyA +1.3 2.4 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b4443 gcvB +1.2 0.7 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b4701 sokX +1.2 1.9 sok-related sRNA, function unknown (RefSeq) compare
b1823 cspC +1.2 3.4 stress protein, member of the CspA-family (NCBI) compare
b0232 yafN +1.1 1.4 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b4066 yjcF +1.1 1.0 hypothetical protein (NCBI) compare
b1217 chaB +1.0 2.2 cation transport regulator (NCBI) compare
b3027 ygiZ +1.0 1.0 conserved inner membrane protein (NCBI) compare
b1563 relE +1.0 1.8 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b1160 elbA +0.9 1.4 hypothetical protein (NCBI) compare
b1824 yobF +0.9 2.5 hypothetical protein (NCBI) compare
b3649 rpoZ +0.9 2.9 DNA-directed RNA polymerase subunit omega (NCBI) compare
b1882 cheY +0.9 0.9 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b0240 crl +0.9 5.7 DNA-binding transcriptional regulator (NCBI) compare
b1542 ydfI +0.9 2.3 predicted mannonate dehydrogenase (NCBI) compare
b2498 upp +0.8 1.7 uracil phosphoribosyltransferase (VIMSS) compare
b2262 menB +0.8 1.5 naphthoate synthase (NCBI) compare
b0407 yajC +0.8 3.1 preprotein translocase subunit YajC (NCBI) compare
b4217 ytfK +0.8 4.1 orf, hypothetical protein (VIMSS) compare
b3753 rbsR +0.8 6.4 DNA-binding transcriptional repressor of ribose metabolism (NCBI) compare
b1954 dsrA +0.8 2.4 regulatory antisense RNA (NCBI) compare
b4585 sroB +0.8 1.4 Novel sRNA, function unknown (RefSeq) compare
b4458 oxyS +0.7 1.4 global regulatory RNA (NCBI) compare
b0782 moaB +0.7 2.4 molybdopterin biosynthesis protein B (NCBI) compare
b4451 ryhB +0.7 1.6 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b2217 rcsB +0.7 4.8 DNA-binding response regulator in two-component regulatory system with RcsC and YojN (NCBI) compare
b2990 hybG +0.7 1.6 hydrogenase 2 accessory protein (NCBI) compare
b0212 gloB +0.7 2.1 predicted hydroxyacylglutathione hydrolase (NCBI) compare
b0015 dnaJ +0.7 4.6 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b1818 manY +0.7 1.4 mannose-specific enzyme IIC component of PTS (NCBI) compare
b1847 yebF +0.7 1.7 predicted protein (RefSeq) compare
b1984 asnW +0.7 1.0 tRNA-Asn (NCBI) compare
b1792 yeaO +0.7 2.2 orf, hypothetical protein (VIMSS) compare
b3206 npr +0.7 3.5 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) compare
b3512 GadE +0.7 3.0 acid-responsive regulator of gadA and gadBC (Katherine Huang) compare
b2698 recX +0.7 2.4 RecA regulator RecX (NCBI) compare
b4025 pgi +0.6 4.4 glucose-6-phosphate isomerase (NCBI) compare
b4071 nrfB +0.6 2.3 formate-dependent nitrite reductase; a penta-haeme cytochrome c (VIMSS) compare
b0866 ybjQ +0.6 1.2 hypothetical protein (NCBI) compare
b3228 sspB +0.6 2.2 ClpXP protease specificity-enhancing factor (NCBI) compare
b0389 yaiA +0.6 1.9 hypothetical protein (NCBI) compare
b1426 ydcH +0.6 1.5 orf, hypothetical protein (VIMSS) compare
b3429 glgA +0.6 5.0 glycogen synthase (NCBI) compare
b4201 priB +0.6 1.5 primosomal replication protein N (NCBI) compare
b0487 cueR +0.6 2.8 DNA-binding transcriptional activator of copper-responsive regulon genes (NCBI) compare
b2145 yeiS +0.6 3.0 predicted inner membrane protein (NCBI) compare
b2762 cysH +0.6 3.9 phosphoadenosine phosphosulfate reductase (NCBI) compare
b1667 ydhR +0.6 1.1 hypothetical protein (NCBI) compare
b1286 rnb +0.6 1.5 exoribonuclease II (NCBI) compare
b4097 phnK +0.6 2.7 carbon-phosphorus lyase complex subunit (NCBI) compare
b4041 plsB +0.6 1.3 glycerol-3-phosphate acyltransferase (VIMSS) compare
b2221 atoD +0.6 2.8 acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit (NCBI) compare
b2181 yejG +0.6 2.7 hypothetical protein (NCBI) compare
b1108 ycfP +0.6 1.4 orf, hypothetical protein (VIMSS) compare
b2659 b2659 +0.6 1.3 orf, hypothetical protein (VIMSS) compare
b1839 yebY +0.6 1.7 hypothetical protein (NCBI) compare
b3432 glgB +0.6 4.9 glycogen branching enzyme (NCBI) compare
b3348 slyX +0.6 2.5 hypothetical protein (NCBI) compare
b1304 pspA +0.6 1.5 regulatory protein for phage-shock-protein operon (NCBI) compare
b2346 vacJ +0.6 4.2 predicted lipoprotein (NCBI) compare
b1842 holE +0.6 1.0 DNA polymerase III, theta subunit (NCBI) compare
b1790 yeaM +0.6 3.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b2642 yfjW +0.6 0.4 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b3650 spoT +0.6 3.3 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) compare
b0624 crcB +0.6 2.1 camphor resistance protein CrcB (NCBI) compare
b4096 phnL +0.6 2.4 carbon-phosphorus lyase complex subunit (NCBI) compare
b2742 nlpD +0.6 3.2 predicted outer membrane lipoprotein (NCBI) compare
b3074 ygjH +0.6 2.2 hypothetical protein (NCBI) compare
b0990 cspG +0.6 0.5 DNA-binding transcriptional regulator (NCBI) compare
b2510 b2510 +0.5 1.4 orf, hypothetical protein (VIMSS) compare
b1104 ycfL +0.5 1.5 hypothetical protein (NCBI) compare
b3195 yrbF +0.5 4.2 predicted toluene transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b2432 yfeY +0.5 1.2 hypothetical protein (NCBI) compare
b2954 yggV +0.5 1.8 putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) compare
b0836 yliH +0.5 1.5 hypothetical protein (NCBI) compare
b1085 b1085 +0.5 1.9 orf, hypothetical protein (VIMSS) compare
b3752 rbsK +0.5 4.0 ribokinase (NCBI) compare
b0623 cspE +0.5 0.9 cold shock protein E (NCBI) compare
b3193 yrbD +0.5 3.6 predicted ABC-type organic solvent transporter (NCBI) compare
b3194 yrbE +0.5 3.6 predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) compare
b2579 yfiD +0.5 1.7 pyruvate formate lyase subunit (NCBI) compare
b3149 yraO +0.5 2.4 DnaA initiator-associating factor for replication initiation (NCBI) compare
b0912 ihfB +0.5 1.8 integration host factor subunit beta (NCBI) compare
b4431 rprA +0.5 1.5 Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) compare
b4048 yjbM +0.5 0.9 hypothetical protein (NCBI) compare
b2419 yfeK +0.5 1.6 hypothetical protein (NCBI) compare
b0778 bioD +0.5 2.0 dethiobiotin synthetase (NCBI) compare
b0388 aroL +0.5 1.5 shikimate kinase II (NCBI) compare
b0364 yaiS +0.5 1.9 orf, hypothetical protein (VIMSS) compare
b4578 insP +0.5 1.7 no description compare
b2421 cysM +0.5 2.3 cysteine synthase B (O-acetylserine sulfhydrolase B) (NCBI) compare
b1804 rnd +0.5 2.1 ribonuclease D (NCBI) compare
b4695 ykgT +0.5 0.6 no description compare
b2071 yegJ +0.5 1.3 hypothetical protein (NCBI) compare
b3034 nudF +0.5 2.3 ADP-ribose pyrophosphatase (NCBI) compare
b4151 frdD +0.5 2.2 fumarate reductase subunit D (NCBI) compare
b0410 yajD +0.5 1.8 hypothetical protein (NCBI) compare
b3192 yrbC +0.5 3.4 predicted ABC-type organic solvent transporter (NCBI) compare
b4294 insA-7 +0.5 0.9 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b1285 gmr +0.5 2.5 modulator of Rnase II stability (NCBI) compare
b2831 mutH +0.5 2.0 DNA mismatch repair protein (NCBI) compare
b4508 peaD +0.5 2.1 putative sensory transduction regulator (VIMSS) compare
b1604 ydgH +0.5 1.2 hypothetical protein (NCBI) compare
b4053 alr +0.5 3.4 alanine racemase (NCBI) compare
b0998 torD +0.5 0.8 chaperone protein TorD (NCBI) compare
b3238 yhcN +0.5 1.6 orf, hypothetical protein (VIMSS) compare
b2911 ssrS +0.5 1.0 6S regulatory RNA (NCBI) compare
b1682 sufC +0.5 2.7 cysteine desulfurase ATPase component (NCBI) compare
b1831 proQ +0.5 1.8 putative solute/DNA competence effector (NCBI) compare
b1312 ycjP +0.5 3.3 predicted sugar transporter subunit: membrane component of ABC superfamily (NCBI) compare
b4522 yciX_1 +0.5 1.1 hypothetical protein (NCBI) compare
b0412 yajI +0.5 1.9 orf, hypothetical protein (VIMSS) compare
b1088 yceD +0.5 1.7 hypothetical protein (NCBI) compare
b4406 yaeP +0.5 1.6 hypothetical protein (NCBI) compare
b1423 ydcJ +0.5 1.8 hypothetical protein (NCBI) compare
b2189 proL +0.5 1.1 tRNA-Pro (NCBI) compare
b0450 glnK +0.5 1.6 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b1249 cls +0.5 2.8 cardiolipin synthetase (NCBI) compare
b3443 yrhA +0.5 0.8 orf, hypothetical protein (VIMSS) compare
b4178 yjeB +0.5 2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b3935 priA +0.5 1.0 primosome assembly protein PriA (NCBI) compare
b1422 ydcI +0.5 2.9 putative transcriptional regulator LYSR-type (VIMSS) compare
b3354 yheU +0.5 2.9 hypothetical protein (NCBI) compare
b2284 nuoF +0.5 2.0 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b3469 zntA +0.5 2.7 zinc, cobalt and lead efflux system (NCBI) compare
b3555 yiaG +0.5 1.2 predicted transcriptional regulator (NCBI) compare
b2535 csiE +0.5 3.4 orf, hypothetical protein (VIMSS) compare
b1290 sapF +0.5 0.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3133 agaV +0.4 2.6 PTS system, cytoplasmic, N-acetylgalactosamine-specific IIB component 2 (EIIB-AGA) (VIMSS) compare
b2101 yegW +0.4 2.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b0108 ppdD +0.4 1.8 predicted major pilin subunit (NCBI) compare
b2366 dsdA +0.4 1.9 D-serine dehydratase (NCBI) compare
b4445 omrB +0.4 2.1 sRNA down regulates OM proteins; positively regulated by OmpR/EnvZ; binds Hfq (RefSeq) compare
b1492 gadC +0.4 2.9 predicted glutamate:gamma-aminobutyric acid antiporter (NCBI) compare
b1769 ydjE +0.4 2.4 predicted transporter (NCBI) compare
b4568 ytjA +0.4 1.1 predicted protein (RefSeq) compare
b4214 cysQ +0.4 3.3 PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) compare
b3131 agaR +0.4 1.7 DNA-binding transcriptional dual regulator (NCBI) compare
b1650 nemA +0.4 2.4 N-ethylmaleimide reductase, FMN-linked (NCBI) compare
b2439 eutL +0.4 2.1 predicted carboxysome structural protein with predicted role in ethanolamine utilization (NCBI) compare
b0710 ybgI +0.4 2.5 conserved metal-binding protein (NCBI) compare
b0503 ybbB +0.4 1.4 tRNA 2-selenouridine synthase, selenophosphate-dependent (NCBI) compare
b1778 yeaA +0.4 0.8 methionine sulfoxide reductase B (NCBI) compare
b1110 ycfJ +0.4 2.6 hypothetical protein (NCBI) compare
b2356 yfdM +0.4 1.3 orf, hypothetical protein (VIMSS) compare
b2272 yfbM +0.4 1.6 hypothetical protein (NCBI) compare
b1960 vsr +0.4 1.2 DNA mismatch endonuclease of very short patch repair (NCBI) compare
b1177 ycgJ +0.4 2.3 hypothetical protein (NCBI) compare
b0870 ltaE +0.4 2.6 L-allo-threonine aldolase, PLP-dependent (NCBI) compare
b1672 ydhW +0.4 1.2 hypothetical protein (NCBI) compare
b4435 isrC +0.4 1.2 unknown RNA (NCBI) compare
b3507 dctR +0.4 3.3 protein involved in metabolism of C4-dicarboxylates (Katherine Huang) compare
b1836 yebV +0.4 1.4 orf, hypothetical protein (VIMSS) compare
b2690 yqaB +0.4 1.8 predicted hydrolase (NCBI) compare
b2287 nuoB +0.4 1.5 NADH dehydrogenase subunit B (NCBI) compare
b2003 yeeT +0.4 0.9 CP4-44 prophage; predicted protein (NCBI) compare
b2923 argO +0.4 2.1 arginine exporter protein (NCBI) compare
b4215 ytfI +0.4 1.0 hypothetical protein (NCBI) compare
b1661 cfa +0.4 2.4 cyclopropane fatty acyl phospholipid synthase (unsaturated-phospholipid methyltransferase) (NCBI) compare
b1306 pspC +0.4 1.0 DNA-binding transcriptional activator (NCBI) compare
b1917 yecC +0.4 1.4 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1725 yniA +0.4 1.5 predicted phosphotransferase/kinase (NCBI) compare
b0841 ybjG +0.4 2.3 undecaprenyl pyrophosphate phosphatase (NCBI) compare
b3516 gadX +0.4 3.1 DNA-binding transcriptional dual regulator (NCBI) compare
b1345 intR +0.4 2.7 Rac prophage; integrase (NCBI) compare
b3504 yhiS +0.4 0.3 hypothetical protein (RefSeq) compare
b2165 yeiN +0.4 1.5 hypothetical protein (NCBI) compare
b1198 dhaM +0.4 1.6 fused predicted dihydroxyacetone-specific PTS enzymes: HPr component/EI component (RefSeq) compare
b2859 ygeO +0.4 0.9 hypothetical protein (RefSeq) compare
b1200 b1200 +0.4 1.7 putative dihydroxyacetone kinase (EC 2.7.1.2) (VIMSS) compare
b0406 tgt +0.4 1.8 queuine tRNA-ribosyltransferase (NCBI) compare
b1557 cspB +0.4 1.1 Qin prophage; cold shock protein (NCBI) compare
b0164 yaeI +0.4 1.8 orf, hypothetical protein (VIMSS) compare
b1205 ychH +0.4 1.0 predicted inner membrane protein (NCBI) compare
b1282 yciH +0.4 2.2 orf, hypothetical protein (VIMSS) compare
b3398 yrfF +0.4 1.4 predicted inner membrane protein (NCBI) compare
b1819 manZ +0.4 1.6 mannose-specific enzyme IID component of PTS (NCBI) compare
b4603 rseX +0.4 0.3 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b0850 ybjC +0.4 1.5 predicted inner membrane protein (NCBI) compare
b1427 rimL +0.4 1.0 ribosomal-protein-L7/L12-serine acetyltransferase (NCBI) compare
b1453 ansP +0.4 1.5 L-asparagine permease (VIMSS) compare
b4633 xisD +0.4 1.4 no description compare
b1334 fnr +0.4 1.3 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b0065 yabI +0.4 1.9 conserved inner membrane protein (NCBI) compare
b1392 paaE +0.4 1.3 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b4554 yibT +0.4 2.0 hypothetical protein (NCBI) compare
b0750 nadA +0.4 2.4 quinolinate synthetase (NCBI) compare
b4544 yfbW +0.4 1.0 hypothetical protein (NCBI) compare
b2904 gcvH +0.4 1.1 glycine cleavage system protein H (NCBI) compare
b3106 yhaK +0.4 1.6 predicted pirin-related protein (NCBI) compare
b2673 nrdH +0.4 1.0 glutaredoxin-like protein (NCBI) compare
b1408 b1408 +0.4 1.6 probable enzyme (VIMSS) compare
b1620 malI +0.4 1.3 DNA-binding transcriptional repressor (NCBI) compare
b0882 clpA +0.4 2.8 ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity (NCBI) compare
b2460 eutQ +0.4 2.3 hypothetical protein (NCBI) compare
b1287 yciW +0.4 1.3 putative oxidoreductase (VIMSS) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in no-phage experiments

For no-phage No-Phage across organisms