Experiment set74S176 for Escherichia coli BW25113

Compare to:

G17

200 most important genes:

  gene name fitness t score description  
b2620 smpB -3.6 -2.4 SsrA-binding protein (NCBI) compare
b0053 surA -3.5 -2.4 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b1361 ydaW -3.3 -1.1 orf, hypothetical protein (VIMSS) compare
b0683 fur -3.1 -1.7 ferric uptake regulator (NCBI) compare
b0737 tolQ -2.7 -4.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3341 rpsG -2.5 -1.8 30S ribosomal protein S7 (NCBI) compare
b3500 gor -2.4 -2.3 glutathione reductase (NCBI) compare
b2576 srmB -2.3 -4.0 ATP-dependent RNA helicase (NCBI) compare
b0200 gmhB -2.2 -1.5 hypothetical protein (NCBI) compare
b2699 recA -2.2 -1.5 recombinase A (NCBI) compare
b1730 ydjO -2.2 -1.4 predicted protein (RefSeq) compare
b1860 ruvB -2.1 -1.8 Holliday junction DNA helicase B (NCBI) compare
b1332 ynaJ -2.1 -1.3 predicted inner membrane protein (NCBI) compare
b4593 ymgI -2.0 -1.4 hypothetical protein (RefSeq) compare
b1291 sapD -2.0 -2.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2279 nuoK -1.9 -2.1 NADH dehydrogenase subunit K (NCBI) compare
b2935 tktA -1.8 -2.1 transketolase 1, thiamin-binding (NCBI) compare
b2289 lrhA -1.7 -8.6 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) compare
b2330 yfcB -1.7 -2.2 putative adenine-specific methylase (VIMSS) compare
b2528 iscA -1.6 -1.5 iron-sulfur cluster assembly protein (NCBI) compare
b3162 deaD -1.6 -3.9 inducible ATP-independent RNA helicase (VIMSS) compare
b3863 polA -1.6 -1.5 DNA polymerase I (NCBI) compare
b3082 ygjM -1.6 -2.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b4647 mokA -1.5 -1.1 no description compare
b0740 tolB -1.5 -4.4 translocation protein TolB precursor (NCBI) compare
b0232 yafN -1.5 -0.9 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b2820 recB -1.5 -1.0 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b4402 yjjY -1.5 -1.2 hypothetical protein (NCBI) compare
b3816 corA -1.5 -6.7 magnesium/nickel/cobalt transporter (NCBI) compare
b3621 rfaC -1.5 -5.6 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0890 ftsK -1.4 -3.2 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b3916 pfkA -1.4 -2.9 6-phosphofructokinase (NCBI) compare
b1855 lpxM -1.4 -4.1 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b1286 rnb -1.4 -2.3 exoribonuclease II (NCBI) compare
b2569 lepA -1.4 -3.5 GTP-binding protein LepA (NCBI) compare
b2168 fruK -1.3 -1.4 1-phosphofructokinase (NCBI) compare
b2939 yqgB -1.3 -1.7 predicted protein (RefSeq) compare
b1765 ydjA -1.3 -1.2 predicted oxidoreductase (NCBI) compare
b1293 sapB -1.3 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0222 lpcA -1.3 -1.6 phosphoheptose isomerase (NCBI) compare
b3839 tatC -1.3 -4.0 TatABCE protein translocation system subunit (NCBI) compare
b2567 rnc -1.3 -0.8 ribonuclease III (NCBI) compare
b3706 trmE -1.3 -4.3 tRNA modification GTPase (NCBI) compare
b3026 qseC -1.2 -3.5 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1346 ydaQ -1.2 -1.5 orf, hypothetical protein (VIMSS) compare
b3613 yibP -1.2 -3.3 putative membrane protein (VIMSS) compare
b3405 ompR -1.2 -3.9 osmolarity response regulator (NCBI) compare
b4201 priB -1.2 -2.9 primosomal replication protein N (NCBI) compare
b3205 yhbJ -1.2 -4.4 hypothetical protein (NCBI) compare
b3778 rep -1.2 -4.8 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b0439 lon -1.1 -3.3 DNA-binding ATP-dependent protease La (NCBI) compare
b0630 lipB -1.1 -1.3 protein of lipoate biosynthesis (VIMSS) compare
b1347 ydaC -1.1 -0.6 Rac prophage; predicted protein (NCBI) compare
b1540 ydfH -1.1 -1.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b1575 dicB -1.1 -1.2 Qin prophage; cell division inhibition protein (NCBI) compare
b4042 dgkA -1.1 -2.1 diacylglycerol kinase (NCBI) compare
b4172 hfq -1.1 -0.7 RNA-binding protein Hfq (NCBI) compare
b3002 yqhA -1.1 -2.0 hypothetical protein (NCBI) compare
b3741 gidA -1.1 -3.2 glucose-inhibited division protein A (NCBI) compare
b2110 yehC -1.0 -1.0 predicted periplasmic pilin chaperone (NCBI) compare
b1292 sapC -1.0 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3935 priA -1.0 -2.6 primosome assembly protein PriA (NCBI) compare
b3609 secB -1.0 -2.6 export protein SecB (NCBI) compare
b3052 rfaE -1.0 -3.2 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1951 rcsA -1.0 -1.5 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b2278 nuoL -1.0 -5.3 NADH dehydrogenase subunit L (NCBI) compare
b4631 ykgQ -1.0 -1.0 no description compare
b3870 glnA -1.0 -2.8 glutamine synthetase (NCBI) compare
b0741 pal -1.0 -2.4 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1863 ruvC -1.0 -1.4 Holliday junction resolvase (NCBI) compare
b1594 dgsA -1.0 -3.3 DNA-binding transcriptional repressor (NCBI) compare
b2114 metG -1.0 -1.9 methionyl-tRNA synthetase (NCBI) compare
b0437 clpP -1.0 -3.7 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b0767 ybhE -1.0 -2.7 6-phosphogluconolactonase (NCBI) compare
b3792 wzxE -0.9 -4.5 O-antigen translocase (NCBI) compare
b3183 obgE -0.9 -1.0 GTPase involved in cell partioning and DNA repair (NCBI) compare
b1936 intG -0.9 -0.9 predicted defective phage integrase (pseudogene) (RefSeq) compare
b0784 moaD -0.9 -2.4 molybdopterin synthase, small subunit (NCBI) compare
b3426 glpD -0.9 -2.8 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b2277 nuoM -0.9 -3.4 NADH dehydrogenase subunit M (NCBI) compare
b1129 phoQ -0.9 -1.7 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b3619 rfaD -0.9 -3.0 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1804 rnd -0.9 -3.2 ribonuclease D (NCBI) compare
b0082 mraW -0.9 -2.5 S-adenosyl-methyltransferase (NCBI) compare
b0888 trxB -0.9 -1.7 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3545 proK -0.9 -1.9 tRNA-Pro (NCBI) compare
b2830 nudH -0.9 -1.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b2343 b2343 -0.9 -1.1 orf, hypothetical protein (VIMSS) compare
b1503 ydeR -0.9 -2.9 predicted fimbrial-like adhesin protein (NCBI) compare
b0471 ybaB -0.9 -2.7 hypothetical protein (NCBI) compare
b1360 ydaV -0.9 -2.7 Rac prophage; predicted DNA replication protein (NCBI) compare
b0049 apaH -0.8 -1.8 diadenosinetetraphosphatase (NCBI) compare
b2250 b2250 -0.8 -2.0 orf, hypothetical protein (VIMSS) compare
b3120 yhaB -0.8 -1.1 orf, hypothetical protein (VIMSS) compare
b2286 nuoC -0.8 -2.8 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b3620 rfaF -0.8 -2.9 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b1824 yobF -0.8 -2.9 hypothetical protein (NCBI) compare
b4179 vacB -0.8 -3.6 putative enzyme (VIMSS) compare
b1426 ydcH -0.8 -1.3 orf, hypothetical protein (VIMSS) compare
b2822 recC -0.8 -3.7 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b0739 tolA -0.8 -2.0 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2283 nuoG -0.8 -3.4 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b3204 ptsN -0.8 -2.8 sugar-specific enzyme IIA component of PTS (NCBI) compare
b3842 rfaH -0.8 -3.1 transcriptional activator RfaH (NCBI) compare
b3781 trxA -0.8 -2.4 thioredoxin 1 (VIMSS) compare
b1182 hlyE -0.8 -0.5 hemolysin E (VIMSS) compare
b4653 yicT -0.8 -1.7 no description compare
b2061 wzb -0.8 -1.7 protein-tyrosine phosphatase (NCBI) compare
b1754 b1754 -0.8 -1.9 orf, hypothetical protein (VIMSS) compare
b1533 ydeD -0.8 -1.5 orf, hypothetical protein (VIMSS) compare
b3398 yrfF -0.8 -2.5 predicted inner membrane protein (NCBI) compare
b2007 yeeX -0.7 -1.0 conserved protein (RefSeq) compare
b1159 mcrA -0.7 -1.0 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b3728 pstS -0.7 -2.1 phosphate transporter subunit (NCBI) compare
b1861 ruvA -0.7 -0.8 Holliday junction DNA helicase motor protein (NCBI) compare
b0051 ksgA -0.7 -2.1 dimethyladenosine transferase (NCBI) compare
b4177 purA -0.7 -0.9 adenylosuccinate synthetase (NCBI) compare
b4453 ldrD -0.7 -1.2 toxic polypeptide, small (NCBI) compare
b2082 ogrK -0.7 -1.1 DNA-binding transcriptional regulator prophage P2 remnant (NCBI) compare
b0850 ybjC -0.7 -2.0 predicted inner membrane protein (NCBI) compare
b4511 ybdZ -0.7 -1.7 hypothetical protein (NCBI) compare
b3844 fre -0.7 -3.4 NAD(P)H-flavin reductase (NCBI) compare
b4535 yniD -0.7 -1.0 predicted protein (RefSeq) compare
b4191 ulaR -0.7 -1.8 DNA-binding transcriptional dual regulator (NCBI) compare
b2258 b2258 -0.7 -0.9 putative transport/receptor protein (VIMSS) compare
b3169 nusA -0.7 -1.4 transcription elongation factor NusA (NCBI) compare
b0858 ybjO -0.7 -1.0 predicted inner membrane protein (NCBI) compare
b1942 fliJ -0.7 -1.1 flagellar biosynthesis chaperone (NCBI) compare
b2597 yfiA -0.7 -1.3 cold shock protein associated with 30S ribosomal subunit (NCBI) compare
b3811 xerC -0.7 -0.8 site-specific tyrosine recombinase XerC (NCBI) compare
b3860 dsbA -0.7 -3.6 periplasmic protein disulfide isomerase I (NCBI) compare
b0564 appY -0.7 -0.9 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b4414 tff -0.7 -0.8 unknown RNA (NCBI) compare
b2906 visC -0.7 -3.0 hypothetical protein (NCBI) compare
b0560 nohB -0.7 -1.1 DLP12 prophage; DNA packaging protein (NCBI) compare
b1185 dsbB -0.7 -1.6 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b4375 prfC -0.7 -2.6 peptide chain release factor 3 (NCBI) compare
b3198 kdsC -0.7 -2.5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b1130 phoP -0.7 -1.4 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b2642 yfjW -0.7 -0.6 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b2281 nuoI -0.7 -1.0 NADH dehydrogenase subunit I (NCBI) compare
b0080 fruR -0.7 -3.2 DNA-binding transcriptional dual regulator (NCBI) compare
b0624 crcB -0.7 -2.4 camphor resistance protein CrcB (NCBI) compare
b1969 yedW -0.7 -2.5 putative 2-component transcriptional regulator (VIMSS) compare
b0018 mokC -0.6 -0.8 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b1175 minD -0.6 -2.4 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b1709 btuD -0.6 -0.7 vitamin B12-transporter ATPase (NCBI) compare
b4698 mgrR -0.6 -2.1 sRNA antisense regulator down regulates YgdQ and EptB, PhoPQ-regulated, Hfq-dependent; affects sensitivity to antimicrobial peptides (RefSeq) compare
b3021 ygiT -0.6 -0.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b1269 rluB -0.6 -1.5 23S rRNA pseudouridylate synthase (NCBI) compare
b2318 truA -0.6 -1.2 tRNA pseudouridine synthase A (NCBI) compare
b2282 nuoH -0.6 -1.2 NADH dehydrogenase subunit H (NCBI) compare
b2363 yfdT -0.6 -1.6 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b0142 folK -0.6 -0.4 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b4203 rplI -0.6 -1.9 50S ribosomal protein L9 (NCBI) compare
b0802 ybiJ -0.6 -1.5 hypothetical protein (NCBI) compare
b4613 dinQ -0.6 -1.0 Damage inducible, function unknown (RefSeq) compare
b2635 ypjK -0.6 -1.2 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b3226 yhcK -0.6 -2.2 putative FADA-type transcriptional regulator (VIMSS) compare
b2940 yqgC -0.6 -2.5 hypothetical protein (NCBI) compare
b1160 elbA -0.6 -0.9 hypothetical protein (NCBI) compare
b4146 yjeK -0.6 -1.3 predicted lysine aminomutase (NCBI) compare
b2432 yfeY -0.6 -1.7 hypothetical protein (NCBI) compare
b1290 sapF -0.6 -0.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0937 ssuE -0.6 -1.0 NAD(P)H-dependent FMN reductase (NCBI) compare
b3806 cyaA -0.6 -2.7 adenylate cyclase (NCBI) compare
b1257 yciE -0.6 -0.3 hypothetical protein (NCBI) compare
b4106 phnC -0.6 -2.3 phosphonate/organophosphate ester transporter subunit (NCBI) compare
b4701 sokX -0.6 -0.4 sok-related sRNA, function unknown (RefSeq) compare
b4458 oxyS -0.6 -0.7 global regulatory RNA (NCBI) compare
b3726 pstA -0.6 -1.7 phosphate transporter subunit (NCBI) compare
b0783 moaC -0.6 -2.4 molybdenum cofactor biosynthesis protein C (NCBI) compare
b1877 yecT -0.6 -1.6 orf, hypothetical protein (VIMSS) compare
b3493 pitA -0.6 -2.7 phosphate transporter, low-affinity (NCBI) compare
b3838 tatB -0.6 -2.4 sec-independent translocase (NCBI) compare
b1104 ycfL -0.6 -1.4 hypothetical protein (NCBI) compare
b1259 yciG -0.6 -1.2 orf, hypothetical protein (VIMSS) compare
b0746 valZ -0.6 -1.3 tRNA-Val (NCBI) compare
b2897 ygfY -0.6 -1.4 hypothetical protein (NCBI) compare
b0627 tatE -0.6 -1.3 twin arginine translocase protein E (NCBI) compare
b0623 cspE -0.5 -1.0 cold shock protein E (NCBI) compare
b1812 pabB -0.5 -2.6 para-aminobenzoate synthase component I (NCBI) compare
b4180 rlmB -0.5 -2.9 23S rRNA (Gm2251)-methyltransferase (NCBI) compare
b3210 arcB -0.5 -2.8 hybrid sensory histidine kinase in two-component regulatory system with ArcA (NCBI) compare
b2586 yfiM -0.5 -1.3 predicted protein (RefSeq) compare
b3623 rfaK -0.5 -1.4 lipopolysaccharide core biosynthesis (NCBI) compare
b4513 kdpF -0.5 -0.8 potassium ion accessory transporter subunit (NCBI) compare
b2356 yfdM -0.5 -1.3 orf, hypothetical protein (VIMSS) compare
b1921 fliZ -0.5 -1.5 orf, hypothetical protein (VIMSS) compare
b0912 ihfB -0.5 -1.6 integration host factor subunit beta (NCBI) compare
b3148 yraN -0.5 -1.7 hypothetical protein (NCBI) compare
b0778 bioD -0.5 -2.1 dethiobiotin synthetase (NCBI) compare
b2809 b2809 -0.5 -2.0 orf, hypothetical protein (VIMSS) compare
b0014 dnaK -0.5 -0.9 molecular chaperone DnaK (NCBI) compare
b1712 ihfA -0.5 -0.8 integration host factor subunit alpha (NCBI) compare
b1658 purR -0.5 -2.2 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b1708 nlpC -0.5 -2.4 predicted lipoprotein (NCBI) compare
b1161 ycgX -0.5 -0.7 hypothetical protein (NCBI) compare
b1946 fliN -0.5 -2.0 flagellar motor switch protein (NCBI) compare
b4451 ryhB -0.5 -0.4 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in phage experiments

For phage Phage across organisms