Experiment set74S110 for Escherichia coli BW25113

Compare to:

TP12

200 most important genes:

  gene name fitness t score description  
b3341 rpsG -4.9 -2.5 30S ribosomal protein S7 (NCBI) compare
b2531 iscR -3.9 -2.7 DNA-binding transcriptional repressor (NCBI) compare
b1863 ruvC -3.7 -3.5 Holliday junction resolvase (NCBI) compare
b3409 feoB -3.4 -19.8 ferrous iron transport protein B (NCBI) conserved
b3410 yhgG -3.4 -9.6 predicted DNA-binding transcriptional regulator (NCBI) compare
b0053 surA -3.3 -3.9 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0683 fur -3.1 -1.5 ferric uptake regulator (NCBI) compare
b0145 dksA -3.0 -2.1 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3405 ompR -2.8 -6.0 osmolarity response regulator (NCBI) compare
b0605 ahpC -2.8 -4.5 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b0592 fepB -2.8 -11.2 iron-enterobactin transporter subunit (NCBI) compare
b3408 feoA -2.8 -9.0 ferrous iron transport protein A (NCBI) compare
b2947 gshB -2.6 -4.8 glutathione synthetase (NCBI) compare
b3613 yibP -2.6 -2.5 putative membrane protein (VIMSS) compare
b3026 qseC -2.6 -4.7 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0014 dnaK -2.6 -3.2 molecular chaperone DnaK (NCBI) compare
b0588 fepC -2.4 -8.7 iron-enterobactin transporter subunit (NCBI) compare
b3778 rep -2.4 -10.0 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b0590 fepD -2.4 -7.7 iron-enterobactin transporter subunit (NCBI) compare
b4647 mokA -2.3 -1.3 no description compare
b2181 yejG -2.2 -4.6 hypothetical protein (NCBI) compare
b0589 fepG -2.2 -7.9 iron-enterobactin transporter subunit (NCBI) compare
b2699 recA -2.2 -1.5 recombinase A (NCBI) compare
b2330 yfcB -2.2 -2.6 putative adenine-specific methylase (VIMSS) compare
b2688 gshA -2.1 -6.3 glutamate--cysteine ligase (NCBI) compare
b1130 phoP -2.0 -1.4 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b3229 sspA -2.0 -4.5 stringent starvation protein A (NCBI) compare
b0585 fes -2.0 -5.3 enterobactin/ferric enterobactin esterase (NCBI) compare
b3628 rfaB -2.0 -11.6 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b0759 galE -2.0 -7.3 UDP-galactose-4-epimerase (VIMSS) compare
b3627 rfaI -2.0 -10.7 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b0595 entB -2.0 -10.6 isochorismatase (NCBI) compare
b3839 tatC -1.9 -5.2 TatABCE protein translocation system subunit (NCBI) compare
b3623 rfaK -1.8 -2.5 lipopolysaccharide core biosynthesis (NCBI) compare
b3961 oxyR -1.8 -8.3 DNA-binding transcriptional dual regulator (NCBI) compare
b1175 minD -1.8 -5.7 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b2894 xerD -1.8 -1.2 site-specific tyrosine recombinase XerD (NCBI) compare
b2501 ppk -1.8 -8.3 polyphosphate kinase (NCBI) compare
b1279 yciS -1.8 -1.5 conserved inner membrane protein (NCBI) compare
b1176 minC -1.7 -2.8 septum formation inhibitor (NCBI) compare
b0908 aroA -1.7 -7.1 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b3183 obgE -1.7 -1.4 GTPase involved in cell partioning and DNA repair (NCBI) compare
b0303 ykgI -1.6 -1.1 orf, hypothetical protein (VIMSS) compare
b1693 aroD -1.6 -7.6 3-dehydroquinate dehydratase (NCBI) compare
b0685 ybfE -1.6 -2.3 orf, hypothetical protein (VIMSS) compare
b2329 aroC -1.6 -4.4 chorismate synthase (NCBI) compare
b0594 entE -1.6 -8.3 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex (NCBI) compare
b1138 ymfE -1.5 -1.5 e14 prophage; predicted inner membrane protein (NCBI) compare
b3863 polA -1.5 -1.4 DNA polymerase I (NCBI) compare
b1942 fliJ -1.5 -1.9 flagellar biosynthesis chaperone (NCBI) compare
b3190 yrbA -1.5 -4.7 orf, hypothetical protein (VIMSS) compare
b2318 truA -1.5 -2.4 tRNA pseudouridine synthase A (NCBI) compare
b3644 yicC -1.5 -5.0 hypothetical protein (NCBI) compare
b3387 dam -1.5 -8.0 DNA adenine methylase (NCBI) compare
b3131 agaR -1.5 -3.3 DNA-binding transcriptional dual regulator (NCBI) compare
b0630 lipB -1.4 -1.4 protein of lipoate biosynthesis (VIMSS) compare
b0439 lon -1.4 -3.6 DNA-binding ATP-dependent protease La (NCBI) compare
b2620 smpB -1.4 -1.2 SsrA-binding protein (NCBI) compare
b1765 ydjA -1.4 -1.2 predicted oxidoreductase (NCBI) compare
b3181 greA -1.4 -4.4 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b1160 elbA -1.4 -1.4 hypothetical protein (NCBI) compare
b1524 yneH -1.4 -1.3 predicted glutaminase (NCBI) compare
b0015 dnaJ -1.4 -5.8 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b1452 yncE -1.4 -4.6 hypothetical protein (NCBI) compare
b0881 clpS -1.3 -2.4 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b0739 tolA -1.3 -2.9 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3180 yhbY -1.3 -4.3 predicted RNA-binding protein (NCBI) compare
b0586 entF -1.3 -7.4 enterobactin synthase multienzyme complex component, ATP-dependent (NCBI) conserved
b1323 tyrR -1.3 -4.5 DNA-binding transcriptional dual regulator, tyrosine-binding (NCBI) compare
b0890 ftsK -1.2 -3.1 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2567 rnc -1.2 -0.8 ribonuclease III (NCBI) compare
b1362 rzpR -1.2 -2.0 putative Rac prophage endopeptidase (VIMSS) compare
b3816 corA -1.2 -5.7 magnesium/nickel/cobalt transporter (NCBI) compare
b4515 ybgT -1.2 -1.6 hypothetical protein (NCBI) compare
b1841 yobA -1.2 -1.3 hypothetical protein (NCBI) compare
b0596 entA -1.2 -3.5 2,3-dihydroxybenzoate-2,3-dehydrogenase (NCBI) compare
b3629 rfaS -1.2 -3.7 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3017 sufI -1.2 -6.8 repressor protein for FtsI (NCBI) compare
b1954 dsrA -1.2 -1.4 regulatory antisense RNA (NCBI) compare
b2614 grpE -1.2 -2.1 heat shock protein (NCBI) compare
b0591 ybdA -1.2 -5.9 predicted transporter (NCBI) compare
b3169 nusA -1.2 -1.7 transcription elongation factor NusA (NCBI) compare
b2288 nuoA -1.1 -2.3 NADH dehydrogenase I chain A (VIMSS) compare
b0080 fruR -1.1 -4.0 DNA-binding transcriptional dual regulator (NCBI) compare
b2156 lysP -1.1 -7.0 lysine transporter (NCBI) compare
b1095 fabF -1.1 -6.8 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b4592 yccB -1.1 -2.3 hypothetical protein (RefSeq) compare
b0051 ksgA -1.1 -3.4 dimethyladenosine transferase (NCBI) compare
b3500 gor -1.1 -1.6 glutathione reductase (NCBI) compare
b1905 ftn -1.1 -6.3 ferritin iron storage protein (cytoplasmic) (NCBI) compare
b1347 ydaC -1.1 -0.5 Rac prophage; predicted protein (NCBI) compare
b3281 aroE -1.1 -8.0 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b0730 mngR -1.1 -1.5 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b2570 rseC -1.1 -3.3 RseC protein involved in reduction of the SoxR iron-sulfur cluster (NCBI) compare
b4529 ydbJ -1.1 -0.9 hypothetical protein (NCBI) compare
b3389 aroB -1.1 -6.6 3-dehydroquinate synthase (NCBI) compare
b4702 mgtL -1.1 -1.4 regulatory leader peptide for mgtA (NCBI) compare
b1129 phoQ -1.0 -1.9 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b3977 tyrU -1.0 -0.7 tRNA-Tyr (NCBI) compare
b1583 ynfB -1.0 -2.4 hypothetical protein (NCBI) compare
b0019 nhaA -1.0 -5.5 pH-dependent sodium/proton antiporter (NCBI) compare
b4172 hfq -1.0 -0.7 RNA-binding protein Hfq (NCBI) compare
b3781 trxA -1.0 -3.3 thioredoxin 1 (VIMSS) compare
b0560 nohB -1.0 -2.8 DLP12 prophage; DNA packaging protein (NCBI) compare
b1165 ymgA -1.0 -0.7 hypothetical protein (NCBI) compare
b3484 yhhI -1.0 -1.9 predicted transposase (NCBI) compare
b0858 ybjO -1.0 -1.6 predicted inner membrane protein (NCBI) compare
b2829 ptsP -1.0 -6.6 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b1164 ycgZ -1.0 -0.9 hypothetical protein (NCBI) compare
b0623 cspE -1.0 -1.7 cold shock protein E (NCBI) compare
b1104 ycfL -1.0 -2.0 hypothetical protein (NCBI) compare
b1847 yebF -1.0 -1.3 predicted protein (RefSeq) compare
b1540 ydfH -0.9 -1.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b3237 argR -0.9 -2.3 arginine repressor (NCBI) compare
b3199 yrbK -0.9 -1.7 hypothetical protein (NCBI) compare
b2279 nuoK -0.9 -1.6 NADH dehydrogenase subunit K (NCBI) compare
b2904 gcvH -0.9 -1.9 glycine cleavage system protein H (NCBI) compare
b1861 ruvA -0.9 -0.9 Holliday junction DNA helicase motor protein (NCBI) compare
b0593 entC -0.9 -4.1 isochorismate synthase (NCBI) compare
b1572 ydfB -0.9 -1.4 orf, hypothetical protein (VIMSS) compare
b2935 tktA -0.9 -1.9 transketolase 1, thiamin-binding (NCBI) compare
b0949 uup -0.9 -4.8 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b2822 recC -0.9 -4.3 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b2820 recB -0.9 -1.0 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2677 proV -0.9 -7.0 glycine betaine transporter subunit (NCBI) compare
b4000 hupA -0.9 -2.9 HU, DNA-binding transcriptional regulator, alpha subunit (NCBI) compare
b3706 trmE -0.9 -3.1 tRNA modification GTPase (NCBI) compare
b3624 rfaZ -0.9 -2.1 lipopolysaccharide core biosynthesis protein (NCBI) compare
b1124 potC -0.9 -3.6 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b4175 hflC -0.9 -4.4 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b0357 yaiN -0.8 -1.3 putative alpha helix chain (VIMSS) compare
b4191 ulaR -0.8 -1.9 DNA-binding transcriptional dual regulator (NCBI) compare
b1827 kdgR -0.8 -2.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b1558 cspF -0.8 -2.1 Qin prophage; cold shock protein (NCBI) compare
b2811 ygdK -0.8 -3.5 predicted Fe-S metabolism protein (NCBI) compare
b2846 yqeH -0.8 -0.5 orf, hypothetical protein (VIMSS) compare
b1684 sufA -0.8 -1.6 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b2363 yfdT -0.8 -1.2 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b2506 yfgI -0.8 -1.6 hypothetical protein (NCBI) compare
b3021 ygiT -0.8 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b1859 znuB -0.8 -4.5 high-affinity zinc transporter membrane component (NCBI) compare
b1108 ycfP -0.8 -2.0 orf, hypothetical protein (VIMSS) compare
b0812 dps -0.8 -3.2 DNA protection during starvation conditions (NCBI) compare
b1349 recT -0.8 -3.0 Rac prophage; recombination and repair protein (NCBI) compare
b2504 yfgG -0.8 -1.4 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b0934 ycbM -0.8 -1.5 putative transport system permease protein (VIMSS) compare
b2778 ygcG -0.8 -2.9 orf, hypothetical protein (VIMSS) compare
b2790 yqcA -0.8 -3.3 flavodoxin (NCBI) compare
b3652 recG -0.8 -4.3 ATP-dependent DNA helicase (NCBI) compare
b1503 ydeR -0.8 -2.3 predicted fimbrial-like adhesin protein (NCBI) compare
b2784 relA -0.8 -4.3 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b4413 sokC -0.8 -1.1 regulatory antisense RNA (NCBI) compare
b0405 queA -0.8 -3.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (NCBI) compare
b2017 yefM -0.7 -1.2 orf, hypothetical protein (VIMSS) compare
b3764 yifE -0.7 -2.1 hypothetical protein (NCBI) compare
b3858 yihD -0.7 -2.2 hypothetical protein (NCBI) compare
b3806 cyaA -0.7 -2.8 adenylate cyclase (NCBI) compare
b3095 yqjA -0.7 -2.5 conserved inner membrane protein (NCBI) compare
b1261 trpB -0.7 -2.1 tryptophan synthase subunit beta (NCBI) compare
b4416 rybA -0.7 -1.0 unknown RNA (NCBI) compare
b4042 dgkA -0.7 -1.5 diacylglycerol kinase (NCBI) compare
b1126 potA -0.7 -3.4 putrescine/spermidine ABC transporter ATPase protein (NCBI) compare
b0597 ybdB -0.7 -1.9 hypothetical protein (NCBI) compare
b1123 potD -0.7 -3.1 spermidine/putrescine ABC transporter periplasmic substrate-binding protein (NCBI) compare
b1773 ydjI -0.7 -2.1 predicted aldolase (NCBI) compare
b3625 rfaY -0.7 -3.0 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3933 ftsN -0.7 -3.6 essential cell division protein (NCBI) compare
b4288 fecD -0.7 -4.0 KpLE2 phage-like element; iron-dicitrate transporter subunit (NCBI) compare
b2040 rfbD -0.7 -4.6 dTDP-4-dehydrorhamnose reductase subunit, NAD(P)-binding, of dTDP-L-rhamnose synthase (NCBI) compare
b1690 ydiM -0.7 -1.8 predicted transporter (NCBI) compare
b2038 rfbC -0.7 -3.5 dTDP-4-deoxyrhamnose-3,5-epimerase (NCBI) compare
b4527 b1354 -0.7 -2.2 orf, hypothetical protein (VIMSS) compare
b4181 yjfI -0.7 -1.7 hypothetical protein (NCBI) compare
b3055 htrG -0.7 -4.3 predicted signal transduction protein (SH3 domain) (NCBI) compare
b0921 smtA -0.7 -2.7 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b3911 cpxA -0.7 -3.4 two-component sensor protein (NCBI) compare
b1658 purR -0.7 -2.9 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b3935 priA -0.7 -1.6 primosome assembly protein PriA (NCBI) compare
b0583 entD -0.7 -1.4 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex (NCBI) compare
b1088 yceD -0.7 -2.5 hypothetical protein (NCBI) compare
b0247 ykfG -0.7 -0.9 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b2110 yehC -0.7 -1.0 predicted periplasmic pilin chaperone (NCBI) compare
b2910 zapA -0.7 -3.0 protein that localizes to the cytokinetic ring (NCBI) compare
b4202 rpsR -0.7 -0.7 30S ribosomal protein S18 (NCBI) compare
b0440 hupB -0.6 -2.2 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b4393 trpR -0.6 -2.6 Trp operon repressor (NCBI) compare
b1790 yeaM -0.6 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b4694 yagP -0.6 -1.9 no description compare
b2911 ssrS -0.6 -0.9 6S regulatory RNA (NCBI) compare
b1363 trkG -0.6 -0.4 Rac prophage; potassium transporter subunit (NCBI) compare
b2741 rpoS -0.6 -3.4 RNA polymerase sigma factor (NCBI) compare
b0183 rnhB -0.6 -1.9 ribonuclease HII (NCBI) compare
b0968 yccX -0.6 -1.9 predicted acylphosphatase (NCBI) compare
b2444 yffM -0.6 -1.4 CPZ-55 prophage; predicted protein (NCBI) compare
b4511 ybdZ -0.6 -1.7 hypothetical protein (NCBI) compare
b2934 cmtB -0.6 -0.5 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b2678 proW -0.6 -3.8 glycine betaine transporter subunit (NCBI) compare
b3928 yiiU -0.6 -2.5 hypothetical protein (NCBI) compare
b0506 allR -0.6 -1.9 DNA-binding transcriptional repressor (NCBI) compare
b2517 yfgB -0.6 -3.5 predicted enzyme (NCBI) compare


Specific Phenotypes

For 12 genes in this experiment

For phage Phage in Escherichia coli BW25113

For phage Phage across organisms