Experiment set73S485 for Escherichia coli BW25113

Compare to:

Calbicans

200 most important genes:

  gene name fitness t score description  
b1476 fdnI -4.1 -1.5 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b0949 uup -4.0 -9.6 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b3164 pnp -2.9 -3.1 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0439 lon -2.8 -1.9 DNA-binding ATP-dependent protease La (NCBI) compare
b1758 b1758 -2.6 -1.3 putative cytochrome oxidase (VIMSS) compare
b3791 rffA -2.5 -9.1 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b0143 pcnB -2.5 -5.9 poly(A) polymerase I (VIMSS) compare
b3183 obgE -2.5 -1.7 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4529 ydbJ -2.5 -1.3 hypothetical protein (NCBI) compare
b3977 tyrU -2.5 -0.9 tRNA-Tyr (NCBI) compare
b0232 yafN -2.3 -1.2 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3405 ompR -2.3 -3.1 osmolarity response regulator (NCBI) compare
b2642 yfjW -2.2 -1.8 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b3842 rfaH -2.2 -6.3 transcriptional activator RfaH (NCBI) compare
b1304 pspA -2.2 -4.3 regulatory protein for phage-shock-protein operon (NCBI) compare
b1563 relE -2.2 -2.0 Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) compare
b0014 dnaK -2.1 -2.1 molecular chaperone DnaK (NCBI) compare
b1151 ymfO -2.1 -2.4 e14 prophage; conserved protein (RefSeq) compare
b0564 appY -2.1 -1.0 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b3181 greA -2.1 -5.7 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b3794 rffM -2.1 -5.5 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b1144 ymfJ -2.0 -2.5 orf, hypothetical protein (VIMSS) compare
b1292 sapC -2.0 -2.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1332 ynaJ -2.0 -1.0 predicted inner membrane protein (NCBI) compare
b4438 cyaR -2.0 -3.1 sRNA effector of ompX mRNA instability, cAMP-induced; hfq-dependent (RefSeq) compare
b1090 plsX -1.9 -3.6 glycerolphosphate auxotrophy in plsB background (VIMSS) compare
b0145 dksA -1.9 -2.6 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b2895 fldB -1.9 -3.3 flavodoxin 2 (NCBI) compare
b4394 yjjX -1.9 -2.4 orf, hypothetical protein (VIMSS) compare
b0200 gmhB -1.9 -1.2 hypothetical protein (NCBI) compare
b1792 yeaO -1.8 -2.2 orf, hypothetical protein (VIMSS) compare
b3786 rffE -1.8 -8.0 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b3911 cpxA -1.8 -6.7 two-component sensor protein (NCBI) compare
b3784 rfe -1.8 -11.0 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b1346 ydaQ -1.8 -1.6 orf, hypothetical protein (VIMSS) compare
b3839 tatC -1.8 -3.2 TatABCE protein translocation system subunit (NCBI) compare
b3787 rffD -1.8 -8.6 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b3790 rffC -1.8 -4.6 TDP-fucosamine acetyltransferase (RefSeq) compare
b3630 rfaP -1.8 -7.2 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b1361 ydaW -1.7 -0.6 orf, hypothetical protein (VIMSS) compare
b3631 rfaG -1.7 -11.1 glucosyltransferase I (NCBI) compare
b2808 gcvA -1.7 -3.8 DNA-binding transcriptional dual regulator (NCBI) compare
b0049 apaH -1.6 -1.9 diadenosinetetraphosphatase (NCBI) compare
b1192 ldcA -1.6 -1.1 L,D-carboxypeptidase A (NCBI) compare
b1739 osmE -1.6 -2.2 DNA-binding transcriptional activator (NCBI) compare
b3792 wzxE -1.6 -5.3 O-antigen translocase (NCBI) compare
b4702 mgtL -1.6 -1.8 regulatory leader peptide for mgtA (NCBI) compare
b4481 rffT -1.6 -4.9 4-alpha-L-fucosyltransferase (NCBI) compare
b2318 truA -1.5 -2.3 tRNA pseudouridine synthase A (NCBI) compare
b3341 rpsG -1.5 -1.2 30S ribosomal protein S7 (NCBI) compare
b0737 tolQ -1.5 -1.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2281 nuoI -1.5 -3.0 NADH dehydrogenase subunit I (NCBI) compare
b4418 sraB -1.5 -2.0 unknown RNA (NCBI) compare
b1493 gadB -1.5 -0.8 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b2620 smpB -1.5 -1.0 SsrA-binding protein (NCBI) compare
b1942 fliJ -1.5 -1.1 flagellar biosynthesis chaperone (NCBI) compare
b2175 spr -1.5 -3.1 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b2910 zapA -1.5 -2.5 protein that localizes to the cytokinetic ring (NCBI) compare
b2846 yqeH -1.4 -0.9 orf, hypothetical protein (VIMSS) compare
b1618 uidR -1.4 -2.7 DNA-binding transcriptional repressor (NCBI) compare
b1103 ycfF -1.4 -1.1 orf, hypothetical protein (VIMSS) compare
b4509 ylcG -1.4 -3.4 DLP12 prophage; predicted protein (NCBI) compare
b2934 cmtB -1.3 -0.9 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b1984 asnW -1.3 -0.9 tRNA-Asn (NCBI) compare
b1861 ruvA -1.3 -0.9 Holliday junction DNA helicase motor protein (NCBI) compare
b1823 cspC -1.3 -1.9 stress protein, member of the CspA-family (NCBI) compare
b2082 ogrK -1.3 -3.0 DNA-binding transcriptional regulator prophage P2 remnant (NCBI) compare
b3026 qseC -1.3 -1.9 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b4503 yafF -1.3 -0.7 no description compare
b4642 yoeD -1.3 -2.4 no description compare
b3706 trmE -1.3 -1.7 tRNA modification GTPase (NCBI) compare
b1575 dicB -1.3 -1.1 Qin prophage; cell division inhibition protein (NCBI) compare
b4520 ymgF -1.3 -1.4 hypothetical protein (NCBI) compare
b0018 mokC -1.3 -1.1 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b1307 pspD -1.2 -1.5 peripheral inner membrane phage-shock protein (NCBI) compare
b2136 yohD -1.2 -3.2 orf, hypothetical protein (VIMSS) compare
b4402 yjjY -1.2 -1.0 hypothetical protein (NCBI) compare
b1290 sapF -1.2 -0.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4535 yniD -1.2 -1.1 predicted protein (RefSeq) compare
b4701 sokX -1.2 -0.8 sok-related sRNA, function unknown (RefSeq) compare
b0630 lipB -1.2 -0.8 protein of lipoate biosynthesis (VIMSS) compare
b1175 minD -1.2 -2.8 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b3162 deaD -1.2 -3.7 inducible ATP-independent RNA helicase (VIMSS) compare
b2531 iscR -1.2 -1.2 DNA-binding transcriptional repressor (NCBI) compare
b1465 narV -1.2 -1.5 nitrate reductase 2 (NRZ), gamma subunit (NCBI) compare
b4451 ryhB -1.2 -1.2 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b1236 galU -1.2 -2.7 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0400 phoR -1.2 -5.2 sensory histidine kinase in two-component regulatory system with PhoB (NCBI) compare
b4648 ysaC -1.2 -1.8 no description compare
b4375 prfC -1.2 -3.8 peptide chain release factor 3 (NCBI) compare
b3778 rep -1.1 -5.1 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b4436 ryeC -1.1 -1.5 Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) compare
b1936 intG -1.1 -0.7 predicted defective phage integrase (pseudogene) (RefSeq) compare
b1855 lpxM -1.1 -2.4 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0101 yacG -1.1 -2.9 zinc-binding protein (NCBI) compare
b0627 tatE -1.1 -2.0 twin arginine translocase protein E (NCBI) compare
b2446 yffO -1.1 -2.0 CPZ-55 prophage; predicted protein (NCBI) compare
b2618 b2618 -1.1 -3.0 orf, hypothetical protein (VIMSS) compare
b1963 b1963 -1.1 -2.8 orf, hypothetical protein (VIMSS) compare
b1448 yncA -1.1 -2.0 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b3414 gntY -1.1 -3.5 predicted gluconate transport associated protein (NCBI) compare
b1084 rne -1.1 -3.7 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b1804 rnd -1.1 -2.8 ribonuclease D (NCBI) compare
b2501 ppk -1.1 -5.0 polyphosphate kinase (NCBI) compare
b2258 b2258 -1.0 -0.9 putative transport/receptor protein (VIMSS) compare
b1811 yoaH -1.0 -1.6 hypothetical protein (NCBI) compare
b0741 pal -1.0 -2.1 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1850 eda -1.0 -1.1 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b3205 yhbJ -1.0 -2.1 hypothetical protein (NCBI) compare
b0739 tolA -1.0 -1.4 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1293 sapB -1.0 -0.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0624 crcB -1.0 -2.2 camphor resistance protein CrcB (NCBI) compare
b1095 fabF -1.0 -3.2 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b3387 dam -1.0 -6.0 DNA adenine methylase (NCBI) compare
b0912 ihfB -1.0 -2.4 integration host factor subunit beta (NCBI) compare
b3761 trpT -1.0 -1.2 tRNA-Trp (NCBI) compare
b1658 purR -1.0 -3.0 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b4431 rprA -1.0 -1.3 Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) compare
b3626 rfaJ -1.0 -3.2 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase (NCBI) compare
b2198 ccmD -1.0 -1.3 cytochrome c biogenesis protein (NCBI) compare
b3493 pitA -1.0 -4.3 phosphate transporter, low-affinity (NCBI) compare
b1730 ydjO -1.0 -0.6 predicted protein (RefSeq) compare
b1728 ydjM -1.0 -1.2 predicted inner membrane protein regulated by LexA (RefSeq) compare
b4202 rpsR -1.0 -1.1 30S ribosomal protein S18 (NCBI) compare
b2399 yfeD -1.0 -3.1 predicted DNA-binding transcriptional regulator (RefSeq) compare
b0389 yaiA -1.0 -1.5 hypothetical protein (NCBI) compare
b4179 vacB -0.9 -3.8 putative enzyme (VIMSS) compare
b2142 yohK -0.9 -3.3 predicted inner membrane protein (NCBI) compare
b1712 ihfA -0.9 -0.6 integration host factor subunit alpha (NCBI) compare
b0167 glnD -0.9 -3.3 PII uridylyl-transferase (NCBI) compare
b3742 mioC -0.9 -2.5 flavodoxin (NCBI) compare
b4697 yrdF -0.9 -2.9 no description compare
b1104 ycfL -0.9 -1.0 hypothetical protein (NCBI) compare
b1269 rluB -0.9 -2.9 23S rRNA pseudouridylate synthase (NCBI) compare
b1839 yebY -0.9 -2.4 hypothetical protein (NCBI) compare
b4242 mgtA -0.9 -5.0 magnesium transporter (NCBI) compare
b2187 yejL -0.9 -2.0 hypothetical protein (NCBI) compare
b0948 ycbY -0.9 -4.1 predicted methyltransferase (NCBI) compare
b4172 hfq -0.9 -0.6 RNA-binding protein Hfq (NCBI) compare
b1388 paaA -0.9 -2.6 predicted multicomponent oxygenase/reductase subunit for phenylacetic acid degradation (NCBI) compare
b4048 yjbM -0.9 -1.0 hypothetical protein (NCBI) compare
b2104 thiM -0.9 -2.0 hydroxyethylthiazole kinase (NCBI) compare
b3204 ptsN -0.9 -2.4 sugar-specific enzyme IIA component of PTS (NCBI) compare
b1259 yciG -0.9 -1.5 orf, hypothetical protein (VIMSS) compare
b0677 nagA -0.9 -3.2 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b1753 ynjA -0.8 -1.3 hypothetical protein (NCBI) compare
b2706 gutM -0.8 -1.6 DNA-binding transcriptional activator of glucitol operon (NCBI) compare
b0560 nohB -0.8 -1.3 DLP12 prophage; DNA packaging protein (NCBI) compare
b0688 pgm -0.8 -2.2 phosphoglucomutase (NCBI) compare
b1063 yceB -0.8 -1.5 predicted lipoprotein (NCBI) compare
b3500 gor -0.8 -1.0 glutathione reductase (NCBI) compare
b4104 phnE -0.8 -1.5 phosphonate/organophosphate ester transporter subunit (NCBI) compare
b3836 b3836 -0.8 -2.1 orf, hypothetical protein (VIMSS) compare
b1186 nhaB -0.8 -3.9 NhaB sodium/proton transporter (Katherine Huang) compare
b4522 yciX_1 -0.8 -2.1 hypothetical protein (NCBI) compare
b0142 folK -0.8 -0.4 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1670 ydhU -0.8 -2.5 predicted cytochrome (NCBI) compare
b1147 ymfL -0.8 -1.6 e14 prophage; predicted DNA-binding transcriptional regulator (RefSeq) compare
b2168 fruK -0.8 -0.7 1-phosphofructokinase (NCBI) compare
b1012 b1012 -0.8 -2.0 orf, hypothetical protein (VIMSS) compare
b1661 cfa -0.8 -2.9 cyclopropane fatty acyl phospholipid synthase (unsaturated-phospholipid methyltransferase) (NCBI) compare
b3426 glpD -0.8 -2.4 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b4552 yrhC -0.8 -0.8 no description compare
b1765 ydjA -0.8 -0.5 predicted oxidoreductase (NCBI) compare
b0683 fur -0.8 -0.4 ferric uptake regulator (NCBI) compare
b3961 oxyR -0.8 -4.3 DNA-binding transcriptional dual regulator (NCBI) compare
b2174 b2174 -0.8 -4.2 orf, hypothetical protein (VIMSS) compare
b3870 glnA -0.7 -1.9 glutamine synthetase (NCBI) compare
b2990 hybG -0.7 -1.2 hydrogenase 2 accessory protein (NCBI) compare
b1837 yebW -0.7 -0.9 orf, hypothetical protein (VIMSS) compare
b2369 evgA -0.7 -1.9 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b1724 ydiZ -0.7 -0.9 hypothetical protein (NCBI) compare
b3644 yicC -0.7 -2.9 hypothetical protein (NCBI) compare
b3009 yghB -0.7 -3.7 conserved inner membrane protein (NCBI) compare
b0866 ybjQ -0.7 -0.7 hypothetical protein (NCBI) compare
b0357 yaiN -0.7 -0.8 putative alpha helix chain (VIMSS) compare
b2678 proW -0.7 -3.5 glycine betaine transporter subunit (NCBI) compare
b0406 tgt -0.7 -2.8 queuine tRNA-ribosyltransferase (NCBI) compare
b1378 ydbK -0.7 -2.8 fused predicted pyruvate-flavodoxin oxidoreductase: conserved protein/conserved protein/FeS binding protein (NCBI) compare
b1502 ydeQ -0.7 -1.2 predicted fimbrial-like adhesin protein (NCBI) compare
b1177 ycgJ -0.7 -2.4 hypothetical protein (NCBI) compare
b0685 ybfE -0.7 -1.4 orf, hypothetical protein (VIMSS) compare
b1881 cheZ -0.7 -2.7 chemotaxis regulator, protein phosphatase for CheY (NCBI) compare
b1884 cheR -0.7 -1.7 chemotaxis regulator, protein-glutamate methyltransferase (NCBI) compare
b2208 napF -0.7 -2.6 ferredoxin-type protein, predicted role in electron transfer to periplasmic nitrate reductase (NapA) (NCBI) compare
b1589 ynfG -0.7 -1.5 oxidoreductase, Fe-S subunit (NCBI) compare
b2314 dedD -0.7 -1.8 putative lipoprotein (VIMSS) compare
b3857 mobA -0.7 -2.2 molybdopterin-guanine dinucleotide biosynthesis protein A (NCBI) compare
b1859 znuB -0.7 -2.3 high-affinity zinc transporter membrane component (NCBI) compare
b4411 ecnB -0.7 -2.4 entericidin B membrane lipoprotein (NCBI) compare
b2080 b2080 -0.7 -1.0 orf, hypothetical protein (VIMSS) compare
b3979 thrT -0.7 -0.2 tRNA-Thr (NCBI) compare
b1515 lsrD -0.7 -1.9 AI2 transporter (NCBI) compare
b1158 pin -0.7 -2.7 e14 prophage; site-specific DNA recombinase (NCBI) compare
b2398 yfeC -0.7 -1.6 orf, hypothetical protein (VIMSS) compare
b4325 yjiC -0.6 -1.9 orf, hypothetical protein (VIMSS) compare
b2481 hyfA -0.6 -2.4 hydrogenase 4 Fe-S subunit (VIMSS) compare
b0423 thiI -0.6 -2.2 thiamine biosynthesis protein ThiI (NCBI) compare
b2867 xdhB -0.6 -2.3 xanthine dehydrogenase, FAD-binding subunit (NCBI) compare
b0028 fkpB -0.6 -2.7 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in yeast experiments

For yeast Yeast across organisms