Experiment set72S540 for Escherichia coli BW25113

Compare to:

no stress control

200 most important genes:

  gene name fitness t score description  
b2279 nuoK -3.4 -4.1 NADH dehydrogenase subunit K (NCBI) compare
b1291 sapD -2.6 -3.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1860 ruvB -2.4 -1.6 Holliday junction DNA helicase B (NCBI) compare
b0232 yafN -2.2 -1.2 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b0053 surA -2.2 -9.3 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3811 xerC -2.2 -2.1 site-specific tyrosine recombinase XerC (NCBI) compare
b2935 tktA -2.1 -3.2 transketolase 1, thiamin-binding (NCBI) compare
b2318 truA -2.1 -4.5 tRNA pseudouridine synthase A (NCBI) compare
b0890 ftsK -2.1 -5.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2699 recA -2.0 -1.9 recombinase A (NCBI) compare
b1861 ruvA -1.9 -1.9 Holliday junction DNA helicase motor protein (NCBI) compare
b3613 yibP -1.9 -5.5 putative membrane protein (VIMSS) compare
b0142 folK -1.9 -1.0 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b1286 rnb -1.8 -3.7 exoribonuclease II (NCBI) compare
b2287 nuoB -1.8 -4.3 NADH dehydrogenase subunit B (NCBI) compare
b0741 pal -1.8 -4.1 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2569 lepA -1.7 -5.3 GTP-binding protein LepA (NCBI) compare
b0738 tolR -1.7 -4.4 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0114 aceE -1.7 -1.2 pyruvate dehydrogenase subunit E1 (NCBI) compare
b3183 obgE -1.7 -2.0 GTPase involved in cell partioning and DNA repair (NCBI) compare
b2277 nuoM -1.7 -8.0 NADH dehydrogenase subunit M (NCBI) compare
b2284 nuoF -1.6 -5.2 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b3839 tatC -1.6 -7.5 TatABCE protein translocation system subunit (NCBI) compare
b1863 ruvC -1.6 -2.8 Holliday junction resolvase (NCBI) compare
b2286 nuoC -1.5 -4.9 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b0630 lipB -1.5 -2.0 protein of lipoate biosynthesis (VIMSS) compare
b2830 nudH -1.5 -1.8 dinucleoside polyphosphate hydrolase (NCBI) compare
b4676 yoaK -1.5 -1.1 expressed protein (RefSeq) compare
b2278 nuoL -1.5 -8.5 NADH dehydrogenase subunit L (NCBI) compare
b4593 ymgI -1.5 -1.0 hypothetical protein (RefSeq) compare
b2283 nuoG -1.5 -7.3 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b3181 greA -1.5 -6.7 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b0739 tolA -1.4 -4.0 cell envelope integrity inner membrane protein TolA (NCBI) compare
b2276 nuoN -1.4 -4.7 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b0740 tolB -1.4 -5.0 translocation protein TolB precursor (NCBI) compare
b0683 fur -1.4 -2.0 ferric uptake regulator (NCBI) compare
b1185 dsbB -1.4 -2.8 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b1677 lpp -1.4 -2.1 murein lipoprotein (NCBI) compare
b2820 recB -1.3 -1.5 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3741 gidA -1.3 -5.7 glucose-inhibited division protein A (NCBI) compare
b4239 treC -1.3 -2.8 trehalose-6-P hydrolase (NCBI) compare
b1550 b1550 -1.3 -1.4 orf, hypothetical protein (VIMSS) compare
b4146 yjeK -1.3 -3.4 predicted lysine aminomutase (NCBI) compare
b2894 xerD -1.3 -1.2 site-specific tyrosine recombinase XerD (NCBI) compare
b3426 glpD -1.2 -4.1 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b4535 yniD -1.2 -1.4 predicted protein (RefSeq) compare
b3838 tatB -1.2 -5.6 sec-independent translocase (NCBI) compare
b1613 manA -1.2 -2.6 mannose-6-phosphate isomerase (VIMSS) compare
b3290 trkA -1.2 -2.8 potassium transporter peripheral membrane component (NCBI) compare
b2285 nuoE -1.2 -2.5 NADH dehydrogenase subunit E (NCBI) compare
b0222 lpcA -1.2 -3.1 phosphoheptose isomerase (NCBI) compare
b0688 pgm -1.2 -3.9 phosphoglucomutase (NCBI) compare
b0729 sucD -1.2 -5.2 succinyl-CoA synthetase subunit alpha (NCBI) compare
b2288 nuoA -1.2 -3.5 NADH dehydrogenase I chain A (VIMSS) compare
b0737 tolQ -1.2 -2.9 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1607 ydgC -1.1 -1.1 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b2188 yejM -1.1 -7.1 predicted hydrolase, inner membrane (NCBI) compare
b4702 mgtL -1.1 -2.8 regulatory leader peptide for mgtA (NCBI) compare
b2282 nuoH -1.1 -3.4 NADH dehydrogenase subunit H (NCBI) compare
b1176 minC -1.1 -3.4 septum formation inhibitor (NCBI) compare
b0049 apaH -1.1 -2.7 diadenosinetetraphosphatase (NCBI) compare
b1850 eda -1.1 -2.0 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b0722 sdhD -1.1 -4.0 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b3261 fis -1.0 -2.5 DNA-binding protein Fis (NCBI) compare
b2297 pta -1.0 -0.9 phosphate acetyltransferase (NCBI) compare
b3916 pfkA -1.0 -3.0 6-phosphofructokinase (NCBI) compare
b2280 nuoJ -1.0 -3.3 NADH dehydrogenase subunit J (NCBI) compare
b0439 lon -1.0 -4.2 DNA-binding ATP-dependent protease La (NCBI) compare
b3619 rfaD -1.0 -4.4 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1084 rne -1.0 -3.6 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b1281 pyrF -1.0 -1.9 orotidine 5'-phosphate decarboxylase (NCBI) compare
b0721 sdhC -1.0 -4.1 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b4066 yjcF -1.0 -0.6 hypothetical protein (NCBI) compare
b3706 trmE -1.0 -3.7 tRNA modification GTPase (NCBI) compare
b1334 fnr -1.0 -3.2 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b0438 clpX -1.0 -5.0 ATP-dependent protease ATP-binding subunit (NCBI) compare
b0033 carB -1.0 -7.4 carbamoyl-phosphate synthase large subunit (NCBI) compare
b2912 ygfA -1.0 -2.7 putative ligase (VIMSS) compare
b0728 sucC -1.0 -5.1 succinyl-CoA synthetase subunit beta (NCBI) compare
b2620 smpB -1.0 -1.3 SsrA-binding protein (NCBI) compare
b3778 rep -1.0 -5.4 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b2281 nuoI -1.0 -2.5 NADH dehydrogenase subunit I (NCBI) compare
b3405 ompR -0.9 -4.2 osmolarity response regulator (NCBI) compare
b0726 sucA -0.9 -3.4 alpha-ketoglutarate decarboxylase (NCBI) compare
b0677 nagA -0.9 -3.7 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b4202 rpsR -0.9 -2.0 30S ribosomal protein S18 (NCBI) compare
b3792 wzxE -0.9 -5.2 O-antigen translocase (NCBI) compare
b1480 sra -0.9 -1.4 30S ribosomal subunit protein S22 (NCBI) compare
b2424 cysU -0.9 -2.7 sulfate/thiosulfate transporter subunit (NCBI) compare
b0437 clpP -0.9 -4.1 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3725 pstB -0.9 -0.6 phosphate transporter subunit (NCBI) compare
b0720 gltA -0.9 -4.0 citrate synthase (NCBI) compare
b1382 ynbE -0.9 -1.5 predicted lipoprotein (NCBI) compare
b1434 ydcN -0.9 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b2531 iscR -0.9 -1.6 DNA-binding transcriptional repressor (NCBI) compare
b1292 sapC -0.9 -1.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3860 dsbA -0.9 -4.9 periplasmic protein disulfide isomerase I (NCBI) compare
b3816 corA -0.9 -6.2 magnesium/nickel/cobalt transporter (NCBI) compare
b4699 fnrS -0.9 -0.8 FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) compare
b1429 tehA -0.9 -1.3 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b2528 iscA -0.9 -2.1 iron-sulfur cluster assembly protein (NCBI) compare
b3386 rpe -0.9 -0.8 ribulose-phosphate 3-epimerase (NCBI) compare
b1855 lpxM -0.9 -3.1 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b2501 ppk -0.8 -5.1 polyphosphate kinase (NCBI) compare
b0724 sdhB -0.8 -4.2 succinate dehydrogenase, FeS subunit (NCBI) compare
b4163 glyV -0.8 -1.0 tRNA-Gly (NCBI) compare
b2168 fruK -0.8 -1.2 1-phosphofructokinase (NCBI) compare
b0888 trxB -0.8 -2.9 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3236 mdh -0.8 -5.0 malate dehydrogenase (NCBI) compare
b2567 rnc -0.8 -1.1 ribonuclease III (NCBI) compare
b2082 ogrK -0.8 -1.2 DNA-binding transcriptional regulator prophage P2 remnant (NCBI) compare
b4472 yhdP -0.8 -7.1 conserved membrane protein, predicted transporter (NCBI) compare
b3642 pyrE -0.8 -2.8 orotate phosphoribosyltransferase (NCBI) compare
b0032 carA -0.8 -4.4 carbamoyl-phosphate synthase small subunit (NCBI) compare
b1777 b1777 -0.8 -0.9 orf, hypothetical protein (VIMSS) compare
b1062 pyrC -0.8 -4.3 dihydroorotase (NCBI) compare
b4172 hfq -0.8 -0.7 RNA-binding protein Hfq (NCBI) compare
b3621 rfaC -0.8 -4.3 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0723 sdhA -0.8 -5.5 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b4414 tff -0.8 -2.0 unknown RNA (NCBI) compare
b2822 recC -0.8 -3.7 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4521 ycgI -0.8 -2.4 hypothetical protein (NCBI) compare
b2808 gcvA -0.8 -2.9 DNA-binding transcriptional dual regulator (NCBI) compare
b3977 tyrU -0.8 -0.9 tRNA-Tyr (NCBI) compare
b3387 dam -0.8 -6.0 DNA adenine methylase (NCBI) compare
b4179 vacB -0.8 -3.4 putative enzyme (VIMSS) compare
b1105 ycfM -0.7 -2.2 predicted outer membrane lipoprotein (NCBI) compare
b1236 galU -0.7 -3.4 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3620 rfaF -0.7 -3.9 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b2707 srlR -0.7 -3.6 DNA-bindng transcriptional repressor (NCBI) compare
b1175 minD -0.7 -3.6 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b4375 prfC -0.7 -3.6 peptide chain release factor 3 (NCBI) compare
b3636 rpmG -0.7 -1.1 50S ribosomal protein L33 (NCBI) compare
b3162 deaD -0.7 -2.9 inducible ATP-independent RNA helicase (VIMSS) compare
b4245 pyrB -0.7 -4.4 aspartate carbamoyltransferase catalytic subunit (NCBI) compare
b0145 dksA -0.7 -2.3 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1685 ydiH -0.7 -1.2 predicted protein (RefSeq) compare
b0080 fruR -0.7 -3.8 DNA-binding transcriptional dual regulator (NCBI) compare
b1461 ydcE -0.7 -1.6 4-oxalocrotonate tautomerase (NCBI) compare
b0014 dnaK -0.7 -1.5 molecular chaperone DnaK (NCBI) compare
b3727 pstC -0.7 -3.7 phosphate transporter subunit (NCBI) compare
b1839 yebY -0.7 -2.9 hypothetical protein (NCBI) compare
b2343 b2343 -0.7 -1.5 orf, hypothetical protein (VIMSS) compare
b0623 cspE -0.7 -1.7 cold shock protein E (NCBI) compare
b0234 yafP -0.7 -1.1 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b2768 ygcP -0.7 -2.7 predicted anti-terminator regulatory protein (NCBI) compare
b1394 paaG -0.7 -1.8 enoyl-CoA hydratase (NCBI) compare
b1235 rssB -0.7 -4.0 response regulator of RpoS (NCBI) compare
b3844 fre -0.7 -3.3 NAD(P)H-flavin reductase (NCBI) compare
b3609 secB -0.7 -2.5 export protein SecB (NCBI) compare
b0209 yafD -0.6 -3.8 hypothetical protein (NCBI) compare
b0945 pyrD -0.6 -4.2 dihydroorotate dehydrogenase (NCBI) compare
b4594 ymgJ -0.6 -2.0 hypothetical protein (RefSeq) compare
b3414 gntY -0.6 -3.2 predicted gluconate transport associated protein (NCBI) compare
b3250 mreC -0.6 -0.8 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b1192 ldcA -0.6 -3.0 L,D-carboxypeptidase A (NCBI) compare
b0611 rna -0.6 -3.4 ribonuclease I (NCBI) compare
b3842 rfaH -0.6 -3.3 transcriptional activator RfaH (NCBI) compare
b1691 ydiN -0.6 -2.7 predicted transporter (RefSeq) compare
b2906 visC -0.6 -3.0 hypothetical protein (NCBI) compare
b4178 yjeB -0.6 -2.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b2512 yfgL -0.6 -3.4 protein assembly complex, lipoprotein component (NCBI) compare
b0632 dacA -0.6 -3.6 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b3027 ygiZ -0.6 -0.4 conserved inner membrane protein (NCBI) compare
b3867 hemN -0.6 -4.6 O2-independent coproporphyrinogen III oxidase (VIMSS) compare
b0580 ybdJ -0.6 -1.8 predicted inner membrane protein (NCBI) compare
b1658 purR -0.6 -2.8 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b4655 ythA -0.6 -1.1 expressed protein (RefSeq) compare
b3870 glnA -0.6 -1.8 glutamine synthetase (NCBI) compare
b2393 nupC -0.6 -4.1 nucleoside (except guanosine) transporter (NCBI) compare
b1536 ydeI -0.6 -0.7 hypothetical protein (NCBI) compare
b0450 glnK -0.6 -1.7 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b0928 aspC -0.6 -4.1 aspartate aminotransferase, PLP-dependent (NCBI) compare
b3979 thrT -0.6 -0.4 tRNA-Thr (NCBI) compare
b0989 cspH -0.6 -1.6 stress protein, member of the CspA-family (NCBI) compare
b2635 ypjK -0.6 -2.4 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b0386 proC -0.6 -2.5 pyrroline-5-carboxylate reductase (NCBI) compare
b2044 wcaL -0.6 -2.2 predicted glycosyl transferase (NCBI) compare
b1648 b1648 -0.6 -0.3 orf, hypothetical protein (VIMSS) compare
b4203 rplI -0.6 -2.6 50S ribosomal protein L9 (NCBI) compare
b2250 b2250 -0.6 -2.3 orf, hypothetical protein (VIMSS) compare
b2814 metZ -0.6 -1.1 tRNA-Met (NCBI) compare
b1936 intG -0.6 -0.7 predicted defective phage integrase (pseudogene) (RefSeq) compare
b3884 yihW -0.6 -3.4 putative DEOR-type transcriptional regulator (VIMSS) compare
b4001 yjaH -0.6 -2.6 hypothetical protein (NCBI) compare
b1284 yciT -0.6 -3.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b1205 ychH -0.6 -1.5 predicted inner membrane protein (NCBI) compare
b1818 manY -0.6 -1.3 mannose-specific enzyme IIC component of PTS (NCBI) compare
b1530 marR -0.6 -2.4 multiple antibiotic resistance protein; repressor of mar operon (VIMSS) compare
b3075 ebgR -0.5 -3.1 DNA-binding transcriptional repressor (NCBI) compare
b0937 ssuE -0.5 -1.3 NAD(P)H-dependent FMN reductase (NCBI) compare
b3849 trkH -0.5 -4.0 potassium transporter (NCBI) compare
b4647 mokA -0.5 -0.5 no description compare
b1679 sufE -0.5 -2.1 cysteine desufuration protein SufE (NCBI) compare
b2977 glcG -0.5 -2.0 hypothetical protein (NCBI) compare
b1573 ydfC -0.5 -1.2 Qin prophage; predicted protein (RefSeq) compare
b3911 cpxA -0.5 -4.2 two-component sensor protein (NCBI) compare
b1630 rsxD -0.5 -2.6 electron transport complex protein RnfD (NCBI) compare
b0866 ybjQ -0.5 -0.9 hypothetical protein (NCBI) compare
b2553 glnB -0.5 -2.5 regulatory protein P-II for glutamine synthetase (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in no stress control experiments