| | gene | name | fitness | t score | description | |
|---|
| b2476 | purC | -10.1 | -3.6 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b0523 | purE | -9.3 | -4.7 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b2499 | purM | -8.7 | -6.0 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b4005 | purD | -8.1 | -14.4 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b2557 | purL | -6.5 | -14.8 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b1281 | pyrF | -6.4 | -4.4 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b2312 | purF | -6.3 | -7.2 | amidophosphoribosyltransferase (NCBI) | compare |
| b2285 | nuoE | -6.2 | -2.8 | NADH dehydrogenase subunit E (NCBI) | compare |
| b4232 | fbp | -6.0 | -12.3 | fructose-1,6-bisphosphatase (NCBI) | compare |
| b2281 | nuoI | -5.4 | -4.1 | NADH dehydrogenase subunit I (NCBI) | compare |
| b1863 | ruvC | -5.2 | -3.2 | Holliday junction resolvase (NCBI) | compare |
| b0522 | purK | -5.1 | -8.1 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b4006 | purH | -5.1 | -12.2 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b2287 | nuoB | -4.9 | -6.4 | NADH dehydrogenase subunit B (NCBI) | compare |
| b2284 | nuoF | -4.8 | -7.7 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b3977 | tyrU | -4.7 | -1.0 | tRNA-Tyr (NCBI) | compare |
| b3870 | glnA | -4.7 | -3.3 | glutamine synthetase (NCBI) | compare |
| b1261 | trpB | -4.6 | -2.5 | tryptophan synthase subunit beta (NCBI) | compare |
| b2286 | nuoC | -4.5 | -6.9 | NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) | compare |
| b2564 | pdxJ | -4.5 | -7.2 | pyridoxal phosphate biosynthetic protein (NCBI) | compare |
| b3619 | rfaD | -4.3 | -5.1 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b1861 | ruvA | -4.1 | -2.5 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b2283 | nuoG | -4.1 | -9.9 | NADH:ubiquinone oxidoreductase, chain G (RefSeq) | compare |
| b2276 | nuoN | -4.1 | -6.8 | NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) | compare |
| b2278 | nuoL | -4.0 | -12.0 | NADH dehydrogenase subunit L (NCBI) | compare |
| b2277 | nuoM | -3.9 | -10.4 | NADH dehydrogenase subunit M (NCBI) | compare |
| b4139 | aspA | -3.7 | -9.7 | aspartate ammonia-lyase (aspartase) (VIMSS) | compare |
| b0049 | apaH | -3.7 | -4.9 | diadenosinetetraphosphatase (NCBI) | compare |
| b0738 | tolR | -3.7 | -5.8 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0737 | tolQ | -3.6 | -4.5 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0740 | tolB | -3.6 | -6.1 | translocation protein TolB precursor (NCBI) | compare |
| b1260 | trpA | -3.5 | -4.8 | tryptophan synthase subunit alpha (NCBI) | compare |
| b0726 | sucA | -3.5 | -5.3 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b2288 | nuoA | -3.5 | -4.0 | NADH dehydrogenase I chain A (VIMSS) | compare |
| b2279 | nuoK | -3.4 | -1.8 | NADH dehydrogenase subunit K (NCBI) | compare |
| b4647 | mokA | -3.4 | -1.4 | no description | compare |
| b0721 | sdhC | -3.4 | -3.4 | succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) | compare |
| b2320 | pdxB | -3.3 | -7.2 | erythronate-4-phosphate dehydrogenase (NCBI) | compare |
| b3979 | thrT | -3.2 | -0.7 | tRNA-Thr (NCBI) | compare |
| b2280 | nuoJ | -3.2 | -4.8 | NADH dehydrogenase subunit J (NCBI) | compare |
| b0222 | lpcA | -3.2 | -3.4 | phosphoheptose isomerase (NCBI) | compare |
| b0564 | appY | -3.2 | -0.9 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b0729 | sucD | -3.1 | -3.0 | succinyl-CoA synthetase subunit alpha (NCBI) | compare |
| b3613 | yibP | -3.1 | -7.1 | putative membrane protein (VIMSS) | compare |
| b0437 | clpP | -3.0 | -6.1 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b3621 | rfaC | -3.0 | -7.3 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b2500 | purN | -3.0 | -2.9 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b0728 | sucC | -3.0 | -6.7 | succinyl-CoA synthetase subunit beta (NCBI) | compare |
| b0739 | tolA | -3.0 | -5.1 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b2282 | nuoH | -3.0 | -4.5 | NADH dehydrogenase subunit H (NCBI) | compare |
| b3642 | pyrE | -2.9 | -5.2 | orotate phosphoribosyltransferase (NCBI) | compare |
| b0439 | lon | -2.9 | -6.7 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b0945 | pyrD | -2.9 | -9.8 | dihydroorotate dehydrogenase (NCBI) | compare |
| b0200 | gmhB | -2.9 | -1.7 | hypothetical protein (NCBI) | compare |
| b0109 | nadC | -2.9 | -8.0 | nicotinate-nucleotide pyrophosphorylase (NCBI) | compare |
| b3236 | mdh | -2.8 | -8.0 | malate dehydrogenase (NCBI) | compare |
| b3082 | ygjM | -2.7 | -1.2 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1062 | pyrC | -2.7 | -8.8 | dihydroorotase (NCBI) | compare |
| b0750 | nadA | -2.7 | -4.2 | quinolinate synthetase (NCBI) | compare |
| b0907 | serC | -2.6 | -5.2 | phosphoserine aminotransferase (NCBI) | compare |
| b2894 | xerD | -2.5 | -1.2 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b4676 | yoaK | -2.5 | -0.7 | expressed protein (RefSeq) | compare |
| b1290 | sapF | -2.4 | -1.8 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3414 | gntY | -2.4 | -4.9 | predicted gluconate transport associated protein (NCBI) | compare |
| b0723 | sdhA | -2.4 | -8.0 | succinate dehydrogenase flavoprotein subunit (NCBI) | compare |
| b3620 | rfaF | -2.4 | -5.1 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b0149 | mrcB | -2.4 | -11.8 | penicillin-binding protein 1b (NCBI) | compare |
| b1262 | trpC | -2.4 | -3.1 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b0052 | pdxA | -2.4 | -8.1 | 4-hydroxythreonine-4-phosphate dehydrogenase (NCBI) | compare |
| b1192 | ldcA | -2.4 | -3.7 | L,D-carboxypeptidase A (NCBI) | compare |
| b0145 | dksA | -2.3 | -3.4 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b1292 | sapC | -2.3 | -2.6 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0928 | aspC | -2.3 | -7.4 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b0724 | sdhB | -2.2 | -4.2 | succinate dehydrogenase, FeS subunit (NCBI) | compare |
| b1291 | sapD | -2.2 | -1.9 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0990 | cspG | -2.2 | -1.3 | DNA-binding transcriptional regulator (NCBI) | compare |
| b3844 | fre | -2.1 | -4.7 | NAD(P)H-flavin reductase (NCBI) | compare |
| b0741 | pal | -2.1 | -3.6 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b0630 | lipB | -2.1 | -1.2 | protein of lipoate biosynthesis (VIMSS) | compare |
| b0438 | clpX | -2.1 | -5.5 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b2846 | yqeH | -2.0 | -0.7 | orf, hypothetical protein (VIMSS) | compare |
| b0683 | fur | -2.0 | -1.4 | ferric uptake regulator (NCBI) | compare |
| b4520 | ymgF | -2.0 | -2.4 | hypothetical protein (NCBI) | compare |
| b3290 | trkA | -1.9 | -1.3 | potassium transporter peripheral membrane component (NCBI) | compare |
| b4177 | purA | -1.9 | -1.3 | adenylosuccinate synthetase (NCBI) | compare |
| b1235 | rssB | -1.9 | -6.5 | response regulator of RpoS (NCBI) | compare |
| b0722 | sdhD | -1.9 | -2.1 | succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) | compare |
| b2574 | nadB | -1.9 | -7.8 | L-aspartate oxidase (NCBI) | compare |
| b1418 | cybB | -1.8 | -1.3 | cytochrome b(561) (VIMSS) | compare |
| b1612 | fumA | -1.8 | -2.5 | fumarate hydratase (fumarase A), aerobic Class I (NCBI) | compare |
| b1575 | dicB | -1.8 | -1.5 | Qin prophage; cell division inhibition protein (NCBI) | compare |
| b3839 | tatC | -1.8 | -3.9 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0053 | surA | -1.8 | -4.7 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b1264 | trpE | -1.8 | -3.9 | anthranilate synthase component I (NCBI) | compare |
| b2830 | nudH | -1.8 | -1.3 | dinucleoside polyphosphate hydrolase (NCBI) | compare |
| b3052 | rfaE | -1.7 | -3.2 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b4407 | thiS | -1.7 | -2.1 | sulfur carrier protein ThiS (NCBI) | compare |
| b3806 | cyaA | -1.7 | -5.5 | adenylate cyclase (NCBI) | compare |
| b4042 | dgkA | -1.7 | -1.9 | diacylglycerol kinase (NCBI) | compare |
| b2820 | recB | -1.6 | -1.1 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b3811 | xerC | -1.6 | -2.9 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b0585 | fes | -1.6 | -5.1 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b2318 | truA | -1.6 | -1.7 | tRNA pseudouridine synthase A (NCBI) | compare |
| b4048 | yjbM | -1.6 | -1.4 | hypothetical protein (NCBI) | compare |
| b1882 | cheY | -1.6 | -0.6 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b3405 | ompR | -1.6 | -3.4 | osmolarity response regulator (NCBI) | compare |
| b1144 | ymfJ | -1.6 | -2.8 | orf, hypothetical protein (VIMSS) | compare |
| b4146 | yjeK | -1.5 | -2.5 | predicted lysine aminomutase (NCBI) | compare |
| b1346 | ydaQ | -1.5 | -0.8 | orf, hypothetical protein (VIMSS) | compare |
| b2103 | thiD | -1.5 | -5.1 | phosphomethylpyrimidine kinase (NCBI) | compare |
| b1977 | asnT | -1.5 | -2.6 | tRNA-Asn (NCBI) | compare |
| b2831 | mutH | -1.5 | -3.8 | DNA mismatch repair protein (NCBI) | compare |
| b1105 | ycfM | -1.5 | -2.3 | predicted outer membrane lipoprotein (NCBI) | compare |
| b1351 | racC | -1.5 | -0.8 | Rac prophage; predicted protein (NCBI) | compare |
| b1130 | phoP | -1.5 | -2.7 | DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) | compare |
| b3849 | trkH | -1.5 | -7.1 | potassium transporter (NCBI) | compare |
| b3994 | thiC | -1.5 | -8.9 | thiamine biosynthesis protein ThiC (NCBI) | compare |
| b2699 | recA | -1.5 | -1.7 | recombinase A (NCBI) | compare |
| b1348 | lar | -1.5 | -1.3 | Rac prophage; restriction alleviation protein (NCBI) | compare |
| b1533 | ydeD | -1.5 | -2.1 | orf, hypothetical protein (VIMSS) | compare |
| b0430 | cyoC | -1.4 | -4.0 | cytochrome o ubiquinol oxidase subunit III (NCBI) | compare |
| b3991 | thiG | -1.4 | -4.6 | thiamin biosynthesis, thiazole moiety (VIMSS) | compare |
| b4503 | yafF | -1.4 | -0.6 | no description | compare |
| b1263 | trpD | -1.4 | -1.9 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b1058 | yceO | -1.4 | -0.4 | hypothetical protein (NCBI) | compare |
| b0080 | fruR | -1.4 | -3.4 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3761 | trpT | -1.4 | -1.1 | tRNA-Trp (NCBI) | compare |
| b1129 | phoQ | -1.4 | -2.6 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b0432 | cyoA | -1.4 | -6.9 | cytochrome o ubiquinol oxidase subunit II (NCBI) | compare |
| b3169 | nusA | -1.4 | -1.4 | transcription elongation factor NusA (NCBI) | compare |
| b2343 | b2343 | -1.3 | -1.7 | orf, hypothetical protein (VIMSS) | compare |
| b1855 | lpxM | -1.3 | -3.4 | lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) | compare |
| b0429 | cyoD | -1.3 | -3.2 | cytochrome o ubiquinol oxidase subunit IV (NCBI) | compare |
| b1744 | astE | -1.3 | -4.5 | succinylglutamate desuccinylase (NCBI) | compare |
| b1949 | fliQ | -1.3 | -2.1 | flagellar biosynthesis protein Q (NCBI) | compare |
| b1183 | umuD | -1.3 | -1.4 | DNA polymerase V, subunit D (NCBI) | compare |
| b4179 | vacB | -1.3 | -4.1 | putative enzyme (VIMSS) | compare |
| b3992 | thiF | -1.3 | -5.6 | thiamin biosynthesis, thiazole moiety (VIMSS) | compare |
| b3728 | pstS | -1.2 | -3.0 | phosphate transporter subunit (NCBI) | compare |
| b2188 | yejM | -1.2 | -5.2 | predicted hydrolase, inner membrane (NCBI) | compare |
| b1778 | yeaA | -1.2 | -1.9 | methionine sulfoxide reductase B (NCBI) | compare |
| b1482 | osmC | -1.2 | -1.2 | osmotically inducible, stress-inducible membrane protein (NCBI) | compare |
| b3706 | trmE | -1.2 | -3.5 | tRNA modification GTPase (NCBI) | compare |
| b1429 | tehA | -1.2 | -0.7 | potassium-tellurite ethidium and proflavin transporter (NCBI) | compare |
| b4426 | isrA | -1.2 | -2.1 | unknown RNA (NCBI) | compare |
| b4535 | yniD | -1.2 | -1.4 | predicted protein (RefSeq) | compare |
| b1084 | rne | -1.2 | -2.5 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b2329 | aroC | -1.2 | -2.8 | chorismate synthase (NCBI) | compare |
| b0908 | aroA | -1.2 | -3.6 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b1150 | ymfR | -1.1 | -0.7 | e14 prophage; predicted protein (NCBI) | compare |
| b3993 | thiE | -1.1 | -4.3 | thiamine-phosphate pyrophosphorylase (NCBI) | compare |
| b0428 | cyoE | -1.1 | -3.9 | protoheme IX farnesyltransferase (NCBI) | compare |
| b3426 | glpD | -1.1 | -2.5 | sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) | compare |
| b1273 | yciN | -1.1 | -1.2 | hypothetical protein (NCBI) | compare |
| b3389 | aroB | -1.1 | -4.5 | 3-dehydroquinate synthase (NCBI) | compare |
| b3631 | rfaG | -1.1 | -7.0 | glucosyltransferase I (NCBI) | compare |
| b0133 | panC | -1.1 | -3.6 | pantoate--beta-alanine ligase (NCBI) | compare |
| b1182 | hlyE | -1.1 | -0.6 | hemolysin E (VIMSS) | compare |
| b3205 | yhbJ | -1.0 | -2.1 | hypothetical protein (NCBI) | compare |
| b2501 | ppk | -1.0 | -3.9 | polyphosphate kinase (NCBI) | compare |
| b0300 | ykgA | -1.0 | -3.4 | putative ARAC-type regulatory protein (VIMSS) | compare |
| b1347 | ydaC | -1.0 | -0.3 | Rac prophage; predicted protein (NCBI) | compare |
| b0033 | carB | -1.0 | -5.8 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b0134 | panB | -1.0 | -4.7 | 3-methyl-2-oxobutanoate hydroxymethyltransferase (NCBI) | compare |
| b0730 | mngR | -1.0 | -1.3 | DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) | compare |
| b1248 | b1248 | -1.0 | -1.9 | orf, hypothetical protein (VIMSS) | compare |
| b3390 | aroK | -1.0 | -1.1 | shikimate kinase I (NCBI) | compare |
| b0890 | ftsK | -1.0 | -3.7 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b3842 | rfaH | -1.0 | -2.9 | transcriptional activator RfaH (NCBI) | compare |
| b3741 | gidA | -1.0 | -3.8 | glucose-inhibited division protein A (NCBI) | compare |
| b2071 | yegJ | -1.0 | -1.4 | hypothetical protein (NCBI) | compare |
| b0163 | yaeH | -1.0 | -3.0 | hypothetical protein (NCBI) | compare |
| b3237 | argR | -1.0 | -2.6 | arginine repressor (NCBI) | compare |
| b0431 | cyoB | -1.0 | -5.4 | cytochrome o ubiquinol oxidase subunit I (NCBI) | compare |
| b0131 | panD | -0.9 | -2.5 | aspartate 1-decarboxylase precursor (NCBI) | compare |
| b3204 | ptsN | -0.9 | -2.1 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b1286 | rnb | -0.9 | -1.3 | exoribonuclease II (NCBI) | compare |
| b1258 | yciF | -0.9 | -1.0 | hypothetical protein (NCBI) | compare |
| b1001 | yccE | -0.9 | -0.4 | hypothetical protein (NCBI) | compare |
| b3990 | thiH | -0.9 | -3.8 | thiamine biosynthesis protein ThiH (NCBI) | compare |
| b2419 | yfeK | -0.9 | -1.5 | hypothetical protein (NCBI) | compare |
| b0676 | nagC | -0.9 | -3.5 | DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) | compare |
| b1103 | ycfF | -0.9 | -1.0 | orf, hypothetical protein (VIMSS) | compare |
| b1506 | yneL | -0.9 | -1.0 | predicted transcriptional regulator (NCBI) | compare |
| b3616 | tdh | -0.9 | -3.2 | L-threonine 3-dehydrogenase (NCBI) | compare |
| b4571 | wbbL | -0.9 | -1.7 | no description | compare |
| b4527 | b1354 | -0.9 | -3.0 | orf, hypothetical protein (VIMSS) | compare |
| b1481 | b1481 | -0.9 | -4.0 | orf, hypothetical protein (VIMSS) | compare |
| b4402 | yjjY | -0.9 | -0.4 | hypothetical protein (NCBI) | compare |
| b1765 | ydjA | -0.9 | -0.7 | predicted oxidoreductase (NCBI) | compare |
| b3778 | rep | -0.9 | -3.1 | DNA helicase and single-stranded DNA-dependent ATPase (NCBI) | compare |
| b2424 | cysU | -0.9 | -1.7 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b2685 | emrA | -0.8 | -3.4 | multidrug efflux system (NCBI) | compare |
| b3398 | yrfF | -0.8 | -1.9 | predicted inner membrane protein (NCBI) | compare |
| b1539 | ydfG | -0.8 | -2.6 | L-allo-threonine dehydrogenase, NAD(P)-binding (NCBI) | compare |
| b1594 | dgsA | -0.8 | -2.0 | DNA-binding transcriptional repressor (NCBI) | compare |
| b2313 | cvpA | -0.8 | -2.6 | membrane protein required for colicin V production (NCBI) | compare |
| b3203 | yhbH | -0.8 | -1.7 | predicted ribosome-associated, sigma 54 modulation protein (NCBI) | compare |
| b2506 | yfgI | -0.8 | -0.9 | hypothetical protein (NCBI) | compare |
| b2569 | lepA | -0.8 | -1.8 | GTP-binding protein LepA (NCBI) | compare |