Experiment set6S176 for Escherichia coli BL21

Compare to:

Bas48

200 most detrimental genes:

  gene name fitness t score description  
ECD_03798 +1.6 4.0 response regulator in two-component regulatory system with CpxA compare
ECD_02829 +1.4 7.9 putative membrane-anchored secretion pathway M-type protein compare
ECD_01375 +1.4 1.8 putative periplasmic protein compare
ECD_02915 +1.4 3.8 putative fimbrial-like adhesin protein compare
ECD_03488 +1.4 4.3 UDP-glucose:(heptosyl)lipopolysaccharide alpha-1,3-glucosyltransferase; lipopolysaccharide core biosynthesis protein; lipopolysaccharide glucosyltransferase I compare
ECD_02841 +1.4 6.4 bifunctional prepilin leader peptidase/ methylase compare
ECD_03242 +1.4 2.7 shikimate kinase I compare
ECD_02042 +1.3 1.4 DUF2574 family protein compare
ECD_02537 +1.3 11.4 putative L-valine exporter, norvaline resistance protein compare
ECD_02250 +1.3 1.9 uncharacterized protein compare
ECD_02831 +1.3 7.5 putative type II secretion protein GspK compare
ECD_03746 +1.3 6.7 periplasmic protein disulfide isomerase I compare
ECD_03489 +1.2 8.6 lipopolysaccharide core biosynthesis protein compare
ECD_03121 +1.2 1.2 putative membrane protein compare
ECD_02842 +1.2 11.2 putative secreted and surface-associated lipoprotein mucinase compare
ECD_01897 +1.2 2.6 ssuEADCB/tauABCD operon transcriptional activator compare
ECD_02792 +1.2 2.4 oxidative damage protective factor for iron-sulfur proteins compare
ECD_02838 +1.2 8.5 putative type II secretion protein GspD compare
ECD_02840 +1.2 2.5 secretin (GspDbeta) OM localization lipoprotein pilotin compare
ECD_02836 +1.2 7.6 putative type II secretion protein GspF compare
ECD_03118 +1.2 8.3 tRNA-dihydrouridine synthase B compare
ECD_02837 +1.2 7.9 putative type II secretion protein GspE compare
ECD_04111 +1.1 5.8 enamine/imine deaminase, reaction intermediate detoxification compare
ECD_02539 +1.1 8.2 transcriptional repressor of microcin B17 synthesis and multidrug efflux compare
ECD_02834 +1.1 4.5 putative type II secretion protein GspH compare
ECD_02835 +1.1 7.6 putative type II secretion protein GspG compare
ECD_t00077 +1.1 1.8 tRNA-Thr compare
ECD_02122 +1.1 2.1 periplasmic thioredoxin of cytochrome c-type biogenesis compare
ECD_03671 +1.1 3.1 TDP-Fuc4NAc:lipidIIFuc4NAc transferase compare
ECD_02839 +1.1 6.7 putative secretion pathway protein, C-type protein compare
ECD_03355 +1.1 1.3 Putative LuxR family repressor for dicarboxylate transport compare
ECD_01770 +1.1 1.6 D-malate oxidase, NAD-dependent; putative tartrate dehydrogenase compare
ECD_01599 +1.1 1.4 SoxR iron-sulfur cluster reduction factor component; putative membrane-associated NADH oxidoreductase of electron transport complex compare
ECD_00389 +1.1 4.9 ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease compare
ECD_03089 +1.0 7.0 stringent starvation protein A, phage P1 late gene activator, RNAP-associated acid-resistance protein, inactive glutathione S-transferase-like protein compare
ECD_01160 +1.0 5.0 oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I compare
ECD_00956 +1.0 1.7 DUF330 family putative lipoprotein compare
ECD_03349 +1.0 6.9 glutathione oxidoreductase compare
ECD_01404 +1.0 2.5 DUF606 family inner membrane protein compare
ECD_t00038 +1.0 3.2 tRNA-Arg compare
ECD_01046 +1.0 4.7 OPG biosynthetic ACP-dependent transmembrane UDP-glucose beta-1,2 glycosyltransferase; nutrient-dependent cell size regulator, FtsZ assembly antagonist compare
ECD_01928 +1.0 1.6 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase compare
ECD_02770 +0.9 2.9 uncharacterized protein compare
ECD_02777 +0.9 5.4 glutathione synthetase compare
ECD_03486 +0.9 3.9 UDP-glucose:(Glucosyl) LPS alpha1,3-glucosyltransferase WaaO compare
ECD_03033 +0.9 7.0 tRNA pseudouridine synthase B: tRNA pseudouridine(55) synthase and putative tmRNA pseudouridine(342) synthase compare
ECD_00938 +0.9 2.3 aliphatic sulfonate ABC transporter permease compare
ECD_02541 +0.9 7.4 multidrug efflux system protein compare
ECD_02330 +0.9 2.9 penicillin binding protein PBP4B; weak DD-carboxypeptidase activity compare
ECD_00165 +0.9 3.3 uridylyltransferase compare
ECD_04303 +0.9 1.4 KGG family protein compare
ECD_03541 +0.9 1.2 hypothetical protein compare
ECD_02287 +0.9 2.3 DUF2545 family putative inner membrane protein compare
ECD_00682 +0.9 2.2 succinate dehydrogenase, membrane subunit, binds cytochrome b556 compare
ECD_01879 +0.9 1.0 response regulator in two-component regulatory system with BarA compare
ECD_02540 +0.9 7.5 multidrug efflux system compare
ECD_02998 +0.9 2.7 N-acetylgalactosamine-specific enzyme IIB component of PTS compare
ECD_00361 +0.9 2.5 Nrd regulon repressor compare
ECD_03733 +0.9 5.2 transcription antitermination protein compare
ECD_03358 +0.9 1.2 stress response protein acid-resistance protein compare
ECD_01489 +0.9 2.3 transcriptional repressor of multiple antibiotic resistance compare
ECD_01044 +0.9 1.0 OPG biosynthetic transmembrane succinyltransferase compare
ECD_02833 +0.8 2.9 putative type II secretion protein GspI compare
ECD_00481 +0.8 1.7 putative periplasmic pilus chaperone compare
ECD_01801 +0.8 5.8 carboxy-terminal protease for penicillin-binding protein 3 compare
ECD_00231 +0.8 2.6 peptide chain release factor 2 compare
ECD_01857 +0.8 1.9 methyl-accepting chemotaxis protein II compare
ECD_03132 +0.8 1.7 dehydroshikimate reductase, NAD(P)-binding compare
ECD_03756 +0.8 5.7 GTP-binding protein compare
ECD_00962 +0.8 5.3 SOS cell division inhibitor compare
ECD_02508 +0.8 1.9 tmRNA-binding trans-translation protein compare
ECD_00255 +0.8 2.3 50S ribosomal protein L31 type B; alternative zinc-limitation L31 protein compare
ECD_03036 +0.8 2.6 transcription termination/antitermination L factor compare
ECD_02768 +0.8 6.4 biosynthetic arginine decarboxylase, PLP-binding compare
ECD_03241 +0.8 4.5 3-dehydroquinate synthase compare
ECD_01277 +0.8 1.1 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; succinate semialdehyde dehydrogenase compare
ECD_01189 +0.8 2.1 transglutaminase-like TPR-repeat protein compare
ECD_00415 +0.8 4.0 transcriptional repressor compare
ECD_01401 +0.8 2.0 gamma-aminobutyraldehyde dehydrogenase compare
ECD_03266 +0.7 4.0 Fe/S biogenesis protein, putative scaffold/chaperone protein compare
ECD_02543 +0.7 6.7 glutamate-cysteine ligase compare
ECD_02769 +0.7 2.7 uncharacterized protein compare
ECD_01045 +0.7 1.9 OPG biosynthetic periplasmic beta-1,6 branching glycosyltransferase compare
ECD_02538 +0.7 2.7 putative L-valine exporter, norvaline resistance protein compare
ECD_01032 +0.7 0.9 redox enzyme maturation protein (REMP) chaperone for YcdX compare
ECD_03550 +0.7 5.6 hexose phosphate transporter compare
ECD_02879 +0.7 2.5 membrane spanning protein in TonB-ExbB-ExbD complex compare
ECD_00941 +0.7 1.3 NAD(P)H-dependent FMN reductase compare
ECD_02210 +0.7 2.3 NADH:ubiquinone oxidoreductase, chain E compare
ECD_03668 +0.7 2.5 TDP-fucosamine acetyltransferase compare
ECD_02849 +0.7 3.1 glycolate-inducible glc operon transcriptional repressor; autorepressor compare
ECD_01898 +0.7 1.4 nitrogen assimilation regulon transcriptional regulator; autorepressor compare
ECD_00450 +0.7 0.4 conserved protein, rhs-like protein compare
ECD_00774 +0.7 1.6 23S rRNA m(6)A1618 methyltransferase, SAM-dependent compare
ECD_02416 +0.7 2.0 Fe(2+) donor and activity modulator for cysteine desulfurase compare
ECD_02780 +0.7 2.8 putative PilT family AAA+ ATPase compare
ECD_04108 +0.7 5.3 trehalose-specific PTS enzyme: IIB and IIC component compare
ECD_02189 +0.7 1.5 dihydroxynaphthoic acid synthetase compare
ECD_01828 +0.7 1.2 zinc ABC transporter periplasmic binding protein compare
ECD_01012 +0.7 1.3 putative reactive intermediate detoxifying aminoacrylate hydrolase compare
ECD_01403 +0.7 1.5 DUF2526 family protein compare
ECD_02951 +0.7 1.1 antitoxinof the HigB-HigA toxin-antitoxin system compare
ECD_00959 +0.7 2.6 putative peptidase compare
ECD_04048 +0.7 1.7 DUF2170 family protein compare
ECD_00260 +0.7 1.5 reactive chlorine stress species (RCS) resistance protein; pyridine nucleotide-dependent disulfide oxidoreductase family compare
ECD_00412 +0.7 2.8 Hha toxicity attenuator; conjugation-related protein compare
ECD_00858 +0.7 1.6 negative regulator of motility; multicopy suppressor of coaA(Ts) compare
ECD_02746 +0.7 1.1 hypothetical protein compare
ECD_02910 +0.7 2.1 ATP-Grasp family ATPase compare
ECD_02349 +0.6 2.1 phosphate acetyltransferase compare
ECD_02750 +0.6 2.3 methylmalonyl-CoA decarboxylase, biotin-independent compare
ECD_02280 +0.6 1.0 hybrid sensory histidine kinase in two-component regulatory system with EvgA compare
ECD_01798 +0.6 2.6 KDG regulon transcriptional repressor compare
ECD_01814 +0.6 1.2 C-N hydrolase family protein compare
ECD_01427 +0.6 1.0 nitrate/nitrite transporter compare
ECD_01579 +0.6 1.9 inhibitor of replication at Ter, DNA-binding protein compare
ECD_00813 +0.6 1.1 transcriptional regulator of csgD and ybiJI; autoregulator compare
ECD_01922 +0.6 1.9 bifunctional histidinal dehydrogenase/ histidinol dehydrogenase compare
ECD_00273 +0.6 1.7 putative inner membrane protein compare
ECD_02203 +0.6 3.0 NADH:ubiquinone oxidoreductase, membrane subunit L compare
ECD_02100 +0.6 1.9 UPF0153 cysteine cluster protein compare
ECD_04024 +0.6 0.8 fumarate reductase (anaerobic), membrane anchor subunit compare
ECD_00551 +0.6 2.9 enterobactin/ferrienterobactin esterase compare
ECD_t00059 +0.6 1.1 tRNA-Thr compare
ECD_01097 +0.6 3.0 fused glucose-specific PTS enzymes: IIB component/IIC component compare
ECD_01630 +0.6 1.5 LysR family putative transcriptional regulator compare
ECD_02118 +0.6 2.2 essential inner membrane DUF3413 domain-containing protein; lipid A production and membrane permeability factor compare
ECD_01830 +0.6 1.7 zinc ABC transporter permease compare
ECD_02209 +0.6 2.7 NADH:ubiquinone oxidoreductase, chain F compare
ECD_01589 +0.6 1.0 transcriptional repressor of Mal regulon compare
ECD_01138 +0.6 1.7 anti-repressor for YcgE, blue light-responsive; FAD-binding; inactive c-di-GMP phosphodiesterase-like EAL domain protein compare
ECD_01716 +0.6 1.2 arginine succinyltransferase compare
ECD_01786 +0.6 1.6 putative membrane protein/conserved protein compare
ECD_01601 +0.6 1.0 SoxR iron-sulfur cluster reduction factor component; putative membrane protein of electron transport complex compare
ECD_01915 +0.6 1.2 putative TusA family sulfurtransferase compare
ECD_01912 +0.6 1.0 DNA gyrase inhibitor compare
ECD_01366 +0.6 1.7 putative phosphatase inner membrane protein compare
ECD_01565 +0.6 0.6 putative arabinose efflux transporter compare
ECD_04194 +0.6 1.0 uncharacterized protein compare
ECD_00681 +0.6 0.8 succinate dehydrogenase, membrane subunit, binds cytochrome b556 compare
ECD_01820 +0.6 1.4 phosphoribosylglycinamide formyltransferase 2 compare
ECD_00867 +0.6 1.6 arginine ABC transporter permease compare
ECD_01399 +0.6 1.1 putative ABC transporter permease compare
ECD_02404 +0.6 1.2 BamABCDE complex OM biogenesis lipoprotein compare
ECD_00196 +0.6 2.7 DL-methionine transporter subunit compare
ECD_03276 +0.6 2.9 thiosulfate:cyanide sulfurtransferase (rhodanese) compare
ECD_00430 +0.6 2.5 putative fosmidomycin efflux system protein compare
ECD_00499 +0.6 1.3 DLP12 prophage; uncharacterized protein compare
ECD_01624 +0.6 1.1 glutaredoxin-4 compare
ECD_01105 +0.6 2.3 respiratory NADH dehydrogenase 2/cupric reductase compare
ECD_00506 +0.6 1.5 DLP12 prophage; putative phage lysis protein compare
ECD_00455 +0.5 1.2 ureidoglycolate lyase, releasing urea compare
ECD_01863 +0.5 0.9 flagellar class II regulon transcriptional activator, with FlhC compare
ECD_00020 +0.5 1.4 hypothetical protein compare
ECD_01082 +0.5 2.8 23S rRNA pseudouridine(955,2504,2580) synthase compare
ECD_00866 +0.5 2.4 arginine ABC transporter permease compare
ECD_03511 +0.5 3.8 glutamate transporter compare
ECD_00274 +0.5 1.4 ankyrin repeat protein compare
ECD_02205 +0.5 1.9 NADH:ubiquinone oxidoreductase, membrane subunit J compare
ECD_00278 +0.5 2.5 carbamate kinase-like protein compare
ECD_01220 +0.5 2.2 oligopeptide ABC transporter ATPase compare
ECD_00513 +0.5 1.8 hypothetical protein compare
ECD_04339 +0.5 1.6 stress-induced small enterobacterial protein compare
ECD_01954 +0.5 0.5 phosphomannomutase compare
ECD_01735 +0.5 1.6 protease IV (signal peptide peptidase) compare
ECD_01907 +0.5 1.4 hypothetical protein compare
ECD_03665 +0.5 3.8 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase compare
ECD_01692 +0.5 1.0 6-phosphofructokinase II compare
ECD_01969 +0.5 1.1 inner membrane protein compare
ECD_03451 +0.5 0.9 TPR-like repeat protein compare
ECD_02208 +0.5 2.9 NADH:ubiquinone oxidoreductase, chain G compare
ECD_02043 +0.5 2.4 antiporter inner membrane protein compare
ECD_00371 +0.5 2.9 tRNA s(4)U8 sulfurtransferase compare
ECD_04218 +0.5 2.4 metal-binding GTPase compare
ECD_00026 +0.5 1.9 hypothetical protein compare
ECD_04371 +0.5 1.2 DUF2387 family putative metal-binding protein compare
ECD_01586 +0.5 0.8 beta-D-glucuronidase compare
ECD_01174 +0.5 1.2 dihydroxyacetone kinase, C-terminal domain compare
ECD_03657 +0.5 2.8 guanosine pentaphosphatase/exopolyphosphatase compare
ECD_01614 +0.5 1.1 putative membrane fusion protein (MFP) of YdhJK efflux pump compare
ECD_00677 +0.5 1.8 putative periplasmic pilin chaperone compare
ECD_00582 +0.5 1.6 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase compare
ECD_00441 +0.5 1.3 iron export ABC transporter ATPase; peroxide resistance protein compare
ECD_03837 +0.5 1.3 putative [formate-C-acetyltransferase 2]-activating enzyme; pyruvate formate-lyase 1-activating enzyme compare
ECD_02789 +0.5 1.6 DUF469 family protein compare
ECD_00195 +0.5 1.4 putative outer membrane protein compare
ECD_00048 +0.5 1.6 putative 4Fe-4S ferredoxin-type protein compare
ECD_00228 +0.5 1.7 mRNA interferase toxin of the YafO-YafN toxin-antitoxin system compare
ECD_01804 +0.5 1.6 inner membrane PqiA domain protein compare
ECD_04178 +0.5 1.7 N-acetylnuraminic acid outer membrane channel protein compare
ECD_00834 +0.5 1.1 putative capsid scaffolding protein compare
ECD_00765 +0.5 0.9 DUF1768 family protein compare
ECD_00410 +0.5 2.4 maltose O-acetyltransferase compare
ECD_02149 +0.5 1.7 acetyl-CoA:acetoacetyl-CoA transferase, beta subunit compare
ECD_01320 +0.5 1.2 ATP-dependent RNA helicase, specific for 23S rRNA compare
ECD_01974 +0.5 1.8 3-methyl-adenine DNA glycosylase II compare
ECD_03667 +0.5 2.1 glucose-1-phosphate thymidylyltransferase compare
ECD_03304 +0.5 1.8 branched-chain amino acid ABC transporter ATPase compare
ECD_02795 +0.5 3.1 ornithine decarboxylase, constitutive compare
ECD_02878 +0.5 2.4 putative oxidoreductase compare


Specific Phenotypes

None in this experiment

For Escherichia coli BL21 in phage experiments

For phage MOI 10 across organisms