Experiment set6S107 for Escherichia coli BL21

Compare to:

Bas63

200 most detrimental genes:

  gene name fitness t score description  
ECD_02042 +3.1 4.2 DUF2574 family protein compare
ECD_03121 +1.4 1.5 putative membrane protein compare
ECD_00492 +1.3 1.9 hypothetical protein compare
ECD_02825 +1.1 2.1 Pyrophosphorylase compare
ECD_03695 +1.1 1.7 Magnesium and cobalt transport protein corA compare
ECD_01650 +1.1 3.5 component of SufBCD Fe-S cluster assembly scaffold compare
ECD_03798 +1.1 2.5 response regulator in two-component regulatory system with CpxA compare
ECD_02057 +1.1 2.8 putative membrane protein compare
ECD_01048 +1.0 2.2 multicopy suppressor of secY and secA compare
ECD_04303 +1.0 1.4 KGG family protein compare
ECD_00494 +1.0 2.0 DLP12 prophage; putative recombinase compare
ECD_01388 +1.0 2.0 lipoprotein compare
ECD_00681 +0.9 1.3 succinate dehydrogenase, membrane subunit, binds cytochrome b556 compare
ECD_04024 +0.9 1.5 fumarate reductase (anaerobic), membrane anchor subunit compare
ECD_00899 +0.9 2.1 dimethyl sulfoxide reductase, anaerobic, subunit B compare
ECD_02113 +0.9 3.3 16S rRNA pseudouridine(516) synthase compare
ECD_01006 +0.9 1.9 uncharacterized protein compare
ECD_01012 +0.9 1.8 putative reactive intermediate detoxifying aminoacrylate hydrolase compare
ECD_04346 +0.9 2.2 hypothetical protein compare
ECD_01427 +0.9 1.5 nitrate/nitrite transporter compare
ECD_02056 +0.9 2.4 transcriptional activator of csgD and csgBA compare
ECD_01317 +0.8 2.7 DNA endonuclease compare
ECD_01879 +0.8 1.1 response regulator in two-component regulatory system with BarA compare
ECD_01379 +0.8 1.5 putative DNA-binding transcriptional regulator compare
ECD_02103 +0.8 1.4 Zn-stimulated GTPase involved in zinc homeostasis; mutants are cadmium and EDTA sensitive; Zn(2+) binding protein compare
ECD_00439 +0.8 1.9 inner membrane protein; stimulator of the QmcA suppressor of ftsH-htpX compare
ECD_02224 +0.8 2.1 putative NUDIX hydrolase compare
ECD_00274 +0.8 2.0 ankyrin repeat protein compare
ECD_01898 +0.8 1.6 nitrogen assimilation regulon transcriptional regulator; autorepressor compare
ECD_04212 +0.8 1.7 5-methylcytosine-specific restriction enzyme McrBC, subunit McrB compare
ECD_00941 +0.8 1.6 NAD(P)H-dependent FMN reductase compare
ECD_02198 +0.8 2.4 DUF1877 family protein compare
ECD_03653 +0.8 1.8 peptidyl-prolyl cis-trans isomerase C (rotamase C) compare
ECD_00996 +0.8 2.8 hybrid sensory histidine kinase in two-component regulatory system with TorR compare
ECD_02348 +0.8 1.7 ethanolamine utilization protein, putative carboxysome structural protein compare
ECD_01655 +0.8 1.7 1,4-dihydroxy-2-naphthoyl-CoA hydrolase compare
ECD_02915 +0.7 1.6 putative fimbrial-like adhesin protein compare
ECD_02998 +0.7 1.9 N-acetylgalactosamine-specific enzyme IIB component of PTS compare
ECD_00329 +0.7 1.2 anti-RssB factor, RpoS stabilzer during Pi starvation; anti-adapter protein compare
ECD_04388 +0.7 2.1 putative membrane-bound BasS regulator compare
ECD_03530 +0.7 1.2 hypothetical protein compare
ECD_03486 +0.7 2.4 UDP-glucose:(Glucosyl) LPS alpha1,3-glucosyltransferase WaaO compare
ECD_02048 +0.7 1.6 putative hexameric AAA+ MoxR family ATPase compare
ECD_02216 +0.7 2.2 5'-nucleotidase compare
ECD_03877 +0.7 2.4 HU, DNA-binding transcriptional regulator, alpha subunit compare
ECD_00865 +0.7 1.8 arginine ABC transporter periplasmic binding protein compare
ECD_01897 +0.6 1.3 ssuEADCB/tauABCD operon transcriptional activator compare
ECD_02193 +0.6 2.7 putative membrane-anchored DUF883 family ribosome-binding protein compare
ECD_01926 +0.6 1.6 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1- (5'-phosphoribosyl)-4-imidazolecarboxamide isomerase compare
ECD_04373 +0.6 1.9 UV-inducible membrane toxin, DinQ-AgrB type I toxin-antitoxin system compare
ECD_01810 +0.6 2.0 DUF2511 family protein compare
ECD_01208 +0.6 1.9 formyltetrahydrofolate hydrolase compare
ECD_02862 +0.6 2.8 putative ATP-binding protein compare
ECD_04371 +0.6 1.6 DUF2387 family putative metal-binding protein compare
ECD_00981 +0.6 2.2 cytochrome bd-II oxidase, subunit I compare
ECD_01960 +0.6 1.7 putative acyl transferase compare
ECD_03785 +0.6 1.5 putative enzyme IIA component of PTS compare
ECD_01792 +0.6 1.6 23S rRNA m(1)G745 methyltransferase, SAM-dependent compare
ECD_04308 +0.6 1.7 uncharacterized protein compare
ECD_01632 +0.6 2.8 cyclopropane fatty acyl phospholipid synthase, SAM-dependent compare
ECD_02034 +0.6 1.3 hypothetical protein compare
ECD_01261 +0.6 1.4 global regulator of transcription; DeoR family compare
ECD_04251 +0.6 2.1 salt-inducible putative ABC transporter periplasmic binding protein compare
ECD_01262 +0.6 1.7 cyclic-di-GMP phosphodiesterase; csgD regulator; modulator of RNase II stability compare
ECD_01138 +0.6 1.7 anti-repressor for YcgE, blue light-responsive; FAD-binding; inactive c-di-GMP phosphodiesterase-like EAL domain protein compare
ECD_02227 +0.6 2.2 GSH-dependent disulfide bond oxidoreductase compare
ECD_02901 +0.6 1.3 quinol monooxygenase compare
ECD_01774 +0.6 1.3 ribonuclease D compare
ECD_03383 +0.6 3.8 DUF2629 family protein compare
ECD_00834 +0.6 1.4 putative capsid scaffolding protein compare
ECD_01835 +0.6 1.0 UPF0082 family protein compare
ECD_02398 +0.6 1.3 nalidixic acid resistance protein, putative periplasmic protein compare
ECD_02582 +0.6 2.6 uncharacterized protein compare
ECD_04119 +0.6 0.9 SopA-central-domain-like hexapeptide repeat protein compare
ECD_00956 +0.6 0.7 DUF330 family putative lipoprotein compare
ECD_02694 +0.6 0.9 putative LuxR family transcriptional regulator compare
ECD_03532 +0.6 1.3 hypothetical protein compare
ECD_00195 +0.6 1.7 putative outer membrane protein compare
ECD_03997 +0.6 1.6 putative 4Fe-4S mono-cluster protein compare
ECD_01403 +0.6 1.3 DUF2526 family protein compare
ECD_02278 +0.6 1.5 multidrug resistance efflux pump membrane fusion protein compare
ECD_01785 +0.6 1.5 putative membrane-anchored cyclic-di-GMP phosphodiesterase, regulator of cellulose production compare
ECD_00513 +0.6 1.9 hypothetical protein compare
ECD_00742 +0.6 1.7 biotin synthase compare
ECD_02396 +0.6 2.0 uncharacterized protein compare
ECD_01614 +0.6 1.3 putative membrane fusion protein (MFP) of YdhJK efflux pump compare
ECD_00260 +0.5 1.3 reactive chlorine stress species (RCS) resistance protein; pyridine nucleotide-dependent disulfide oxidoreductase family compare
ECD_01275 +0.5 1.9 gamma-glutamyl-gamma-aminobutyrate hydrolase compare
ECD_01066 +0.5 2.1 export chaperone for FlgK and FlgL compare
ECD_02319 +0.5 2.5 uncharacterized protein compare
ECD_00938 +0.5 1.2 aliphatic sulfonate ABC transporter permease compare
ECD_00452 +0.5 1.8 putative DNA-binding transcriptional regulator compare
ECD_00466 +0.5 2.0 allantoate amidohydrolase compare
ECD_02920 +0.5 1.3 DUF1449 family inner membrane protein compare
ECD_00802 +0.5 1.1 ribosomal protein S12 methylthiotransferase compare
ECD_04362 +0.5 0.9 hypothetical protein compare
ECD_02710 +0.5 1.1 CTP:molybdopterin cytidylyltransferase compare
ECD_02524 +0.5 1.2 DUF2892 family inner membrane rhodanese compare
ECD_00377 +0.5 1.0 putative acetyltransferase compare
ECD_01391 +0.5 1.4 BenE family inner membrane putative transporter compare
ECD_00181 +0.5 1.7 ribonuclease HII compare
ECD_02090 +0.5 1.2 nucleoside permease compare
ECD_03112 +0.5 3.1 putative acryloyl-CoA reductase compare
ECD_03541 +0.5 1.0 hypothetical protein compare
ECD_01793 +0.5 1.4 stress protein, member of the CspA-family compare
ECD_02280 +0.5 0.9 hybrid sensory histidine kinase in two-component regulatory system with EvgA compare
ECD_01396 +0.5 0.9 putative DNA-binding transcriptional regulator and putative aminotransferase compare
ECD_04389 +0.5 1.5 hypothetical protein compare
ECD_01695 +0.5 0.9 putative inner membrane protein compare
ECD_03242 +0.5 0.8 shikimate kinase I compare
ECD_00854 +0.5 1.4 glutaredoxin 1, redox coenzyme for ribonucleotide reductase (RNR1a) compare
ECD_01033 +0.5 1.2 DUF1097 family inner membrane protein compare
ECD_02107 +0.5 1.7 microcin C ABC transporter periplasmic binding protein compare
ECD_03436 +0.5 1.8 putative regulatory protein compare
ECD_01798 +0.5 1.9 KDG regulon transcriptional repressor compare
ECD_01046 +0.5 2.2 OPG biosynthetic ACP-dependent transmembrane UDP-glucose beta-1,2 glycosyltransferase; nutrient-dependent cell size regulator, FtsZ assembly antagonist compare
ECD_03381 +0.5 4.2 cellulose synthase, catalytic subunit compare
ECD_03998 +0.5 1.2 GNAT family putative N-acetyltransferase compare
ECD_01589 +0.5 0.9 transcriptional repressor of Mal regulon compare
ECD_00073 +0.5 1.4 3-isopropylmalate dehydratase small subunit compare
ECD_01043 +0.5 1.5 stationary phase cardiolipin synthase 3 compare
ECD_01956 +0.5 1.5 putative glycosyl transferase compare
ECD_01702 +0.5 1.7 chito-oligosaccharide deacetylase compare
ECD_03378 +0.5 4.0 cellulose synthase subunit compare
ECD_01869 +0.5 1.4 L-arabinose ABC transporter periplasmic binding protein compare
ECD_00582 +0.5 1.5 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase compare
ECD_00338 +0.5 1.5 UPF0345 family protein compare
ECD_02175 +0.5 1.2 inactive PncC family protein compare
ECD_03386 +0.5 3.7 DUF3260 family cellulose production inner membrane protein compare
ECD_01032 +0.5 0.8 redox enzyme maturation protein (REMP) chaperone for YcdX compare
ECD_04158 +0.5 2.7 anti-sigma transmembrane signal transducer for ferric citrate transport; periplasmic FecA-bound ferric citrate sensor and cytoplasmic FecI ECF sigma factor activator compare
ECD_01859 +0.4 1.4 fused chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY: sensory histidine kinase/signal sensing protein compare
ECD_01291 +0.4 1.6 putative TIM alpha/beta barrel enzyme compare
ECD_03380 +0.4 3.7 regulator of cellulose synthase, cyclic di-GMP binding compare
ECD_00454 +0.4 1.8 allD operon transcriptional activator compare
ECD_00848 +0.4 1.2 bacteriophage tail fiber protein compare
ECD_02226 +0.4 1.1 glutathione S-transferase compare
ECD_00353 +0.4 1.7 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
ECD_00835 +0.4 1.1 hypothetical protein compare
ECD_02162 +0.4 0.7 ferredoxin involved with ribonucleotide reductase diferric-tyrosyl radical (Y*) cofactor maintenance compare
ECD_02304 +0.4 1.6 DUF1323 family putative DNA-binding protein compare
ECD_01928 +0.4 0.7 phosphoribosyl-AMP cyclohydrolase and phosphoribosyl-ATP pyrophosphatase compare
ECD_02102 +0.4 2.1 putative NAD-dependent D-mannonate oxidoreductase compare
ECD_00594 +0.4 1.4 fluoride efflux channel, dual topology membrane protein compare
ECD_01820 +0.4 1.0 phosphoribosylglycinamide formyltransferase 2 compare
ECD_01579 +0.4 1.6 inhibitor of replication at Ter, DNA-binding protein compare
ECD_00925 +0.4 0.5 putative S-adenosyl-L-methionine-dependent methyltransferase compare
ECD_03425 +0.4 0.8 putative hydrogenase, 4Fe-4S ferredoxin-type component compare
ECD_02063 +0.4 1.6 D-lactate dehydrogenase, FAD-binding, NADH independent compare
ECD_03187 +0.4 1.8 bacterioferritin, iron storage and detoxification protein compare
ECD_01671 +0.4 1.8 phosphoenolpyruvate synthase compare
ECD_02266 +0.4 2.0 beta-ketoacyl-CoA thiolase, anaerobic, subunit compare
ECD_01399 +0.4 0.6 putative ABC transporter permease compare
ECD_00430 +0.4 1.7 putative fosmidomycin efflux system protein compare
ECD_01404 +0.4 0.9 DUF606 family inner membrane protein compare
ECD_00962 +0.4 2.8 SOS cell division inhibitor compare
ECD_02230 +0.4 0.9 transposase_31 family protein compare
ECD_01801 +0.4 3.1 carboxy-terminal protease for penicillin-binding protein 3 compare
ECD_01656 +0.4 1.3 putative FAD-linked oxidoreductase compare
ECD_02043 +0.4 1.7 antiporter inner membrane protein compare
ECD_02071 +0.4 1.6 LrgB family inner membrane protein compare
ECD_03752 +0.4 3.1 coproporphyrinogen III oxidase, SAM and NAD(P)H dependent, oxygen-independent compare
ECD_02061 +0.4 1.2 putative ABC transporter periplasmic binding protein compare
ECD_02228 +0.4 1.3 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase and dihydroneopterin aldolase compare
ECD_02556 +0.4 1.9 sorbitol-responsive srl operon transcriptional activator compare
ECD_01924 +0.4 1.5 histidinol-phosphatase and imidazoleglycerol-phosphate dehydratase compare
ECD_02349 +0.4 0.9 phosphate acetyltransferase compare
ECD_02194 +0.4 1.1 GNAT family putative N-acetyltransferase compare
ECD_01225 +0.4 0.6 putative DGPF domain-containing enzyme compare
ECD_03083 +0.4 2.1 putative N-acetylmannosamine-6-P epimerase compare
ECD_00376 +0.4 1.6 hypothetical protein compare
ECD_01747 +0.4 1.0 methionine sulfoxide reductase B compare
ECD_01189 +0.4 1.0 transglutaminase-like TPR-repeat protein compare
ECD_02626 +0.4 2.4 nucleoside triphosphate pyrophosphohydrolase compare
ECD_00533 +0.4 0.7 copper/silver efflux system, outer membrane component compare
ECD_03868 +0.4 1.3 immediate sulfur donor in thiazole formation compare
ECD_01060 +0.4 1.1 glutaredoxin 2 (Grx2) compare
ECD_01401 +0.4 0.9 gamma-aminobutyraldehyde dehydrogenase compare
ECD_00654 +0.4 1.2 potassium translocating ATPase, subunit B compare
ECD_00830 +0.4 0.8 hypothetical protein compare
ECD_02970 +0.4 1.8 putative quinol oxidase subunit compare
ECD_03645 +0.4 0.9 ilvG operon leader peptide compare
ECD_04090 +0.4 1.8 methionine sulfoxide reductase A compare
ECD_02424 +0.4 1.6 tRNA mC32,mU32 2'-O-methyltransferase, SAM-dependent compare
ECD_01109 +0.4 0.8 L,D-transpeptidase linking Lpp to murein compare
ECD_00617 +0.4 1.4 ribonucleoside hydrolase 1 compare
ECD_04116 +0.4 1.8 c-di-GMP-binding biofilm dispersal mediator protein compare
ECD_00286 +0.4 1.9 2-methylisocitrate lyase compare
ECD_03660 +0.4 0.5 rho operon leader peptide compare
ECD_02792 +0.4 0.9 oxidative damage protective factor for iron-sulfur proteins compare
ECD_00939 +0.4 0.7 alkanesulfonate monooxygenase, FMNH(2)-dependent compare
ECD_01572 +0.4 1.1 pyridine nucleotide transhydrogenase, alpha subunit compare
ECD_00026 +0.4 1.1 hypothetical protein compare
ECD_02055 +0.4 1.5 inner membrane putative sensory kinase in two-component system with YehT compare
ECD_01559 +0.4 0.9 oxidoreductase, membrane subunit compare
ECD_02770 +0.4 1.8 uncharacterized protein compare
ECD_00601 +0.4 1.9 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) compare
ECD_00811 +0.4 1.0 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase; pyrimidine phosphatase; riboflavin synthesis compare
ECD_01716 +0.4 0.9 arginine succinyltransferase compare
ECD_02718 +0.4 1.2 putative 4Fe-4S ferredoxin-type oxidoreductase subunit compare


Specific Phenotypes

None in this experiment

For Escherichia coli BL21 in phage experiments

For phage MOI 10 across organisms