Experiment set6IT063 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

phi19h1_phage 15 MOI

200 most important genes:

  gene name fitness t score description  
GFF2216 -5.4 -10.9 DNA polymerase I (EC 2.7.7.7) compare
GFF2389 -4.5 -2.5 Trk system potassium uptake protein TrkA compare
GFF4353 -4.2 -5.0 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
GFF4355 -3.8 -1.3 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF4162 -3.6 -5.3 DNA repair protein RecN compare
GFF824 -3.5 -5.4 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF4354 -3.2 -3.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
GFF3862 -3.0 -4.9 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
GFF2991 -2.9 -3.6 Tyrosine recombinase XerD compare
GFF1634 -2.9 -2.6 Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) compare
GFF1076 -2.8 -2.8 Aerobic respiration control protein arcA compare
GFF1303 -2.8 -2.0 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
GFF3490 -2.7 -5.9 Exodeoxyribonuclease III (EC 3.1.11.2) compare
GFF1032 -2.6 -1.3 DNA polymerase III psi subunit (EC 2.7.7.7) compare
GFF2517 -2.5 -1.3 [NiFe] hydrogenase nickel incorporation HybF-like protein compare
GFF4653 -2.5 -2.2 TolA protein compare
GFF2061 -2.4 -7.4 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
GFF2881 -2.4 -8.4 WzxE protein compare
GFF4891 -2.4 -10.5 Transport ATP-binding protein CydD compare
GFF4634 -2.4 -7.5 Citrate synthase (si) (EC 2.3.3.1) compare
GFF1900 -2.3 -6.6 Acetate kinase (EC 2.7.2.1) compare
GFF1256 -2.3 -3.7 Chromosome (plasmid) partitioning protein ParA compare
GFF4890 -2.3 -9.2 Transport ATP-binding protein CydC compare
GFF20 -2.3 -6.0 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-) compare
GFF4647 -2.2 -7.6 Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) compare
GFF633 -2.2 -4.9 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF4126 -2.2 -1.2 FIG01047407: hypothetical protein compare
GFF2954 -2.1 -10.0 Aerobic respiration control sensor protein arcB (EC 2.7.3.-) compare
GFF241 -2.1 -6.6 ATP-dependent DNA helicase UvrD/PcrA compare
GFF192 -2.1 -4.9 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)' transl_table=11 compare
GFF4837 -2.0 -7.0 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 compare
GFF773 -2.0 -1.6 probable lipoprotein compare
GFF4646 -2.0 -9.9 Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) compare
GFF948 -2.0 -4.1 DNA polymerase III chi subunit (EC 2.7.7.7) compare
GFF2946 -2.0 -4.4 RNA polymerase sigma-54 factor RpoN compare
GFF1090 -2.0 -3.3 Chaperone protein DnaJ compare
GFF3667 -2.0 -1.6 Cytidylate kinase (EC 2.7.4.25) compare
GFF122 -1.9 -7.2 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
GFF1801 -1.9 -1.3 hypothetical protein compare
GFF632 -1.8 -5.3 Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) compare
GFF2863 -1.8 -1.2 FIG074102: hypothetical protein compare
GFF2276 -1.8 -1.6 Manganese superoxide dismutase (EC 1.15.1.1) compare
GFF603 -1.7 -3.9 NfuA Fe-S protein maturation compare
GFF1901 -1.7 -4.2 Phosphate acetyltransferase (EC 2.3.1.8) compare
GFF3772 -1.7 -1.3 1-phosphofructokinase (EC 2.7.1.56) compare
GFF3595 -1.6 -2.1 Secretion system effector SseG compare
GFF1848 -1.6 -1.2 FIG074102: hypothetical protein compare
GFF3528 -1.6 -2.0 Integration host factor alpha subunit compare
GFF1716 -1.6 -4.8 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA compare
GFF2178 -1.6 -1.0 Thiol peroxidase, Bcp-type (EC 1.11.1.15) compare
GFF969 -1.6 -1.9 FIG007491: hypothetical protein YeeN compare
GFF825 -1.6 -2.6 RNA-binding protein Hfq compare
GFF4454 -1.5 -1.3 Transcriptional regulator of fimbriae expression FimZ (LuxR/UhpA family) compare
GFF1334 -1.5 -1.0 Uncharacterized protein YohL compare
GFF4408 -1.5 -4.0 YbbL ABC transporter ATP-binding protein compare
GFF3426 -1.5 -2.0 Virulence protein MsgA compare
GFF1541 -1.5 -1.8 Flagellar synthesis: repressor of fliC compare
GFF1642 -1.5 -1.2 putative cytoplasmic protein compare
GFF2592 -1.5 -1.8 secreted effector protein compare
GFF3377 -1.4 -3.6 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) compare
GFF2882 -1.4 -5.4 Lipopolysaccharide biosynthesis protein RffA compare
GFF27 -1.4 -1.8 Copper homeostasis protein CutF precursor / Lipoprotein NlpE involeved in surface adhesion compare
GFF635 -1.4 -3.9 Tryptophanyl-tRNA synthetase (EC 6.1.1.2) compare
GFF276 -1.4 -3.7 Potassium uptake protein TrkH compare
GFF2468 -1.4 -1.1 Putative transmembrane transport protein compare
GFF3545 -1.4 -1.2 Transcriptional regulator, AraC family compare
GFF2473 -1.4 -3.9 DNA recombination and repair protein RecO compare
GFF2690 -1.3 -1.2 Peptide transport system permease protein SapC compare
GFF2832 -1.3 -1.5 PTS system, mannose-specific IIC component (EC 2.7.1.69) compare
GFF4652 -1.3 -2.0 Tol biopolymer transport system, TolR protein compare
GFF4409 -1.3 -5.7 YbbM seven transmembrane helix protein compare
GFF55 -1.3 -6.7 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
GFF2541 -1.3 -2.9 putative cytoplasmic protein compare
GFF4460 -1.3 -1.9 Putative inner membrane protein compare
GFF4007 -1.3 -2.5 Flagellar biosynthesis protein FliQ compare
GFF2149 -1.2 -3.8 Malate dehydrogenase (EC 1.1.1.37) compare
GFF109 -1.2 -1.8 DeoR family transcriptional regulator probably related to glycerate, glycolaldehyde metabolism compare
GFF3558 -1.2 -1.5 Iron binding protein SufA for iron-sulfur cluster assembly compare
GFF4016 -1.2 -1.4 Flagellar assembly protein FliH compare
GFF2208 -1.2 -3.5 DNA-damage-inducible protein I compare
GFF355 -1.2 -1.6 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
GFF2470 -1.2 -1.2 4Fe-4S ferredoxin, iron-sulfur binding compare
GFF4586 -1.1 -0.9 Glucosamine-6-phosphate deaminase (EC 3.5.99.6) compare
GFF4417 -1.1 -2.4 Methionine ABC transporter ATP-binding protein compare
GFF121 -1.1 -1.9 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) compare
GFF2092 -1.1 -3.0 FIG074102: hypothetical protein compare
GFF352 -1.1 -1.1 FIG01048298: hypothetical protein compare
GFF1736 -1.1 -1.2 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) compare
GFF4021 -1.1 -1.4 FIG01200701: possible membrane protein compare
GFF4600 -1.1 -2.5 SeqA protein, negative modulator of initiation of replication compare
GFF3183 -1.1 -1.0 FIG01046167: hypothetical protein compare
GFF4774 -1.0 -1.0 FIG074102: hypothetical protein compare
GFF183 -1.0 -5.7 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
GFF4249 -1.0 -3.1 Cu(I)-responsive transcriptional regulator compare
GFF341 -1.0 -0.9 RmbA compare
GFF4390 -1.0 -3.5 Recombination protein RecR compare
GFF3320 -1.0 -1.3 Transcriptional regulator CsgD for 2nd curli operon compare
GFF2720 -1.0 -2.9 Hypothetical YciO protein, TsaC/YrdC paralog compare
GFF3461 -1.0 -0.8 hypothetical protein compare
GFF265 -1.0 -4.4 Twin-arginine translocation protein TatC compare
GFF3491 -1.0 -1.5 FIG01046149: hypothetical protein compare
GFF1119 -1.0 -5.0 Na+/H+ antiporter NhaA type compare
GFF242 -1.0 -2.1 Magnesium and cobalt transport protein CorA compare
GFF1095 -1.0 -0.7 Putative membrane protein compare
GFF2505 -1.0 -1.0 Multiple antibiotic resistance protein MarB compare
GFF2515 -1.0 -0.9 putative outer membrane protein compare
GFF753 -1.0 -1.3 Glutaredoxin 1 compare
GFF4598 -1.0 -2.1 Uncharacterized protein ybfE compare
GFF1750 -0.9 -2.1 GTPase and tRNA-U34 5-formylation enzyme TrmE compare
GFF3502 -0.9 -0.6 PTS system, cellobiose-specific IIB component (EC 2.7.1.69) compare
GFF1914 -0.9 -1.1 Cell division inhibitor compare
GFF3449 -0.9 -1.4 Putative arylsulfatase regulatory protein compare
GFF2785 -0.9 -1.0 FIG01045804: hypothetical protein compare
GFF1785 -0.9 -3.3 Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon compare
GFF3109 -0.9 -1.9 FIG01046062: hypothetical protein compare
GFF522 -0.9 -4.9 Low-affinity inorganic phosphate transporter compare
GFF4061 -0.9 -0.6 putative periplasmic protein compare
GFF2475 -0.9 -1.5 Ribonuclease III (EC 3.1.26.3) compare
GFF249 -0.9 -1.0 L-lysine permease compare
GFF1415 -0.9 -0.8 UPF0337 protein yjbJ compare
GFF2880 -0.9 -3.0 4-alpha-L-fucosyltransferase (EC 2.4.1.-) compare
GFF3364 -0.9 -1.3 Flagellar hook-associated protein FlgL compare
GFF1662 -0.9 -2.0 Chemotaxis response - phosphatase CheZ compare
GFF3567 -0.9 -3.3 Pyruvate kinase (EC 2.7.1.40) compare
GFF3471 -0.9 -2.3 Putative two-component response regulator and GGDEF family protein YeaJ compare
GFF180 -0.9 -0.7 FIG01045455: hypothetical protein compare
GFF2160 -0.9 -1.6 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 compare
GFF2862 -0.9 -1.4 FIG01046381: hypothetical protein compare
GFF190 -0.9 -2.6 SSU rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase (EC 2.1.1.182) compare
GFF4367 -0.9 -2.4 Nitrogen regulatory protein P-II, glnK compare
GFF734 -0.9 -1.0 putative cytoplasmic protein compare
GFF4766 -0.9 -0.9 Invasion protein invH precursor compare
GFF991 -0.9 -1.0 hypothetical protein compare
GFF684 -0.9 -1.5 Putative membrane protein compare
GFF829 -0.9 -0.8 Putative inner membrane protein YjeT (clustered with HflC) compare
GFF3195 -0.9 -1.4 Uncharacterized membrane protein YqjD compare
GFF2968 -0.9 -1.6 Stringent starvation protein A compare
GFF3391 -0.9 -2.2 YcfP protein: probably an esterase that is part of a salvage cluster compare
GFF2173 -0.8 -2.6 Chromosomal replication initiator protein DnaA compare
GFF3423 -0.8 -1.7 FIG00643583: hypothetical protein compare
GFF1672 -0.8 -3.1 Flagellar transcriptional activator FlhC compare
GFF4122 -0.8 -1.1 FIG01046577: hypothetical protein compare
GFF4822 -0.8 -1.8 Queuosine biosynthesis QueD, PTPS-I compare
GFF1939 -0.8 -2.0 FIG00643583: hypothetical protein compare
GFF2679 -0.8 -1.9 Transcriptional repressor protein TyrR compare
GFF1057 -0.8 -1.0 DNA repair protein RadA compare
GFF2022 -0.8 -4.1 hypothetical protein compare
GFF1940 -0.8 -0.8 Putative DNA-binding protein in cluster with Type I restriction-modification system compare
GFF3926 -0.8 -2.1 UPF0265 protein YeeX compare
GFF2220 -0.8 -4.2 Nitrogen regulation protein NR(I) compare
GFF4453 -0.8 -2.1 Fimbriae-like periplasmic protein SfmF compare
GFF3350 -0.8 -1.5 Flagellar biosynthesis protein FlgN compare
GFF1792 -0.8 -1.1 Spermidine export protein MdtJ compare
GFF2989 -0.8 -3.4 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
GFF2305 -0.8 -2.2 Ferredoxin--NADP(+) reductase (EC 1.18.1.2) compare
GFF1081 -0.8 -3.7 UPF0246 protein YaaA compare
GFF110 -0.8 -1.9 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) compare
GFF1666 -0.8 -2.4 Methyl-accepting chemotaxis protein compare
GFF571 -0.8 -2.0 Gluconokinase (EC 2.7.1.12) compare
GFF504 -0.8 -1.5 Putative regulator compare
GFF3907 -0.8 -1.2 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
GFF2850 -0.8 -2.6 Ribosomal RNA small subunit methyltransferase F (EC 2.1.1.-) compare
GFF2425 -0.8 -1.8 FIG074102: hypothetical protein compare
GFF2992 -0.8 -4.9 Flavodoxin 2 compare
GFF387 -0.8 -1.6 Lipopolysaccharide core biosynthesis protein RfaZ compare
GFF3463 -0.8 -0.8 FIG00638667: hypothetical protein compare
GFF2615 -0.8 -2.2 LysR family transcriptional regulator YdcI compare
GFF4537 -0.8 -1.3 CrcB protein compare
GFF707 -0.8 -2.2 Non-specific DNA-binding protein Dps / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1) compare
GFF1221 -0.7 -0.8 hypothetical protein compare
GFF4623 -0.7 -1.6 UDP-galactopyranose mutase (EC 5.4.99.9) compare
GFF1882 -0.7 -2.3 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) compare
GFF4575 -0.7 -2.5 Magnesium and cobalt efflux protein CorC compare
GFF4655 -0.7 -1.1 18K peptidoglycan-associated outer membrane lipoprotein; Peptidoglycan-associated lipoprotein precursor; Outer membrane protein P6; OmpA/MotB precursor compare
GFF4364 -0.7 -2.0 Putative HTH-type transcriptional regulator ybaO compare
GFF4374 -0.7 -0.7 LSU ribosomal protein L36p compare
GFF850 -0.7 -2.0 3-keto-L-gulonate-6-phosphate decarboxylase UlaD (EC 4.1.1.85) (L-ascorbate utilization protein D) compare
GFF356 -0.7 -0.7 'tRNA (guanosine(18)-2'-O)-methyltransferase (EC 2.1.1.34)' transl_table=11 compare
GFF675 -0.7 -4.9 Excinuclease ABC subunit B compare
GFF3990 -0.7 -0.6 hypothetical protein compare
GFF1966 -0.7 -1.1 FIG00638164: hypothetical protein compare
GFF4770 -0.7 -0.8 transposase compare
GFF1756 -0.7 -4.6 DNA recombination and repair protein RecF compare
GFF67 -0.7 -1.7 hypothetical protein compare
GFF1817 -0.7 -1.4 Cytochrome c-type protein NapC compare
GFF945 -0.7 -1.6 Aspartate N-acetyltransferase (EC 2.3.1.17) compare
GFF2201 -0.7 -1.5 putative DNA-binding protein compare
GFF2028 -0.7 -1.2 Type III secretion and flagellar regulator RtsA compare
GFF3659 -0.7 -1.3 FIG01045244: hypothetical protein compare
GFF1214 -0.7 -2.0 Kappa-fimbriae major subunit compare
GFF1813 -0.7 -0.7 Cnu protein compare
GFF1195 -0.7 -2.1 hypothetical protein compare
GFF1518 -0.7 -3.1 Phosphoheptose isomerase (EC 5.3.1.-) compare
GFF188 -0.7 -2.6 Survival protein SurA precursor (Peptidyl-prolyl cis-trans isomerase SurA) (EC 5.2.1.8) compare
GFF787 -0.7 -1.0 FIG00642546: hypothetical protein compare
GFF3288 -0.7 -1.5 Chaperone-modulator protein CbpM compare
GFF1356 -0.7 -0.9 Acetate operon repressor compare
GFF2221 -0.7 -2.5 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
GFF842 -0.7 -2.0 Putative uncharacterized protein YjfN compare
GFF4356 -0.7 -1.3 DNA-binding protein HU-beta compare


Specific Phenotypes

None in this experiment

For Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 in phage experiments

For phage phi19h1_phage across organisms