Experiment set6IT061 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

phi19h1_phage 15 MOI

200 most important genes:

  gene name fitness t score description  
GFF2216 -5.2 -11.0 DNA polymerase I (EC 2.7.7.7) compare
GFF4355 -3.8 -1.3 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF1303 -3.6 -2.1 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
GFF1634 -3.6 -4.1 Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) compare
GFF2276 -3.4 -2.1 Manganese superoxide dismutase (EC 1.15.1.1) compare
GFF4634 -3.2 -10.6 Citrate synthase (si) (EC 2.3.3.1) compare
GFF3490 -3.2 -9.2 Exodeoxyribonuclease III (EC 3.1.11.2) compare
GFF3461 -3.2 -1.4 hypothetical protein compare
GFF2991 -3.2 -4.0 Tyrosine recombinase XerD compare
GFF2061 -3.0 -8.9 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
GFF3862 -2.9 -3.7 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
GFF4162 -2.9 -4.2 DNA repair protein RecN compare
GFF3667 -2.8 -1.9 Cytidylate kinase (EC 2.7.4.25) compare
GFF2946 -2.8 -5.2 RNA polymerase sigma-54 factor RpoN compare
GFF2389 -2.6 -3.0 Trk system potassium uptake protein TrkA compare
GFF4354 -2.6 -3.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
GFF121 -2.5 -3.3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) compare
GFF4890 -2.5 -8.1 Transport ATP-binding protein CydC compare
GFF1076 -2.5 -3.5 Aerobic respiration control protein arcA compare
GFF824 -2.4 -4.0 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF4745 -2.4 -1.6 secretion chaparone compare
GFF2690 -2.4 -2.0 Peptide transport system permease protein SapC compare
GFF4605 -2.4 -1.0 hypothetical protein compare
GFF2881 -2.3 -6.9 WzxE protein compare
GFF3545 -2.3 -1.6 Transcriptional regulator, AraC family compare
GFF4615 -2.2 -1.5 FIG137478: Hypothetical protein YbgI compare
GFF1900 -2.2 -6.5 Acetate kinase (EC 2.7.2.1) compare
GFF4647 -2.1 -5.6 Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) compare
GFF4600 -2.1 -3.2 SeqA protein, negative modulator of initiation of replication compare
GFF4891 -2.0 -9.6 Transport ATP-binding protein CydD compare
GFF3603 -2.0 -1.9 Secretion system apparatus protein SsaM compare
GFF192 -2.0 -5.5 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)' transl_table=11 compare
GFF4646 -2.0 -11.5 Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) compare
GFF3755 -2.0 -1.4 FIG00896318: hypothetical protein compare
GFF122 -2.0 -7.8 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
GFF1090 -2.0 -4.4 Chaperone protein DnaJ compare
GFF633 -2.0 -4.0 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF632 -1.9 -6.7 Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) compare
GFF948 -1.9 -4.6 DNA polymerase III chi subunit (EC 2.7.7.7) compare
GFF4774 -1.9 -1.5 FIG074102: hypothetical protein compare
GFF2954 -1.8 -8.4 Aerobic respiration control sensor protein arcB (EC 2.7.3.-) compare
GFF4837 -1.8 -5.9 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 compare
GFF1032 -1.8 -1.3 DNA polymerase III psi subunit (EC 2.7.7.7) compare
GFF4353 -1.7 -3.3 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
GFF4408 -1.7 -6.4 YbbL ABC transporter ATP-binding protein compare
GFF1750 -1.7 -3.2 GTPase and tRNA-U34 5-formylation enzyme TrmE compare
GFF341 -1.7 -1.2 RmbA compare
GFF4652 -1.7 -2.6 Tol biopolymer transport system, TolR protein compare
GFF2537 -1.7 -1.5 hypothetical protein compare
GFF3230 -1.7 -1.0 Transposase compare
GFF825 -1.6 -2.5 RNA-binding protein Hfq compare
GFF4614 -1.6 -1.0 hypothetical protein compare
GFF1334 -1.6 -1.1 Uncharacterized protein YohL compare
GFF4126 -1.6 -1.0 FIG01047407: hypothetical protein compare
GFF2173 -1.6 -2.9 Chromosomal replication initiator protein DnaA compare
GFF241 -1.5 -5.2 ATP-dependent DNA helicase UvrD/PcrA compare
GFF109 -1.5 -2.0 DeoR family transcriptional regulator probably related to glycerate, glycolaldehyde metabolism compare
GFF20 -1.5 -3.9 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-) compare
GFF2475 -1.5 -1.9 Ribonuclease III (EC 3.1.26.3) compare
GFF3395 -1.5 -1.1 Putative outer membrane protein compare
GFF4810 -1.5 -1.5 CRISPR-associated protein, Cse3 family compare
GFF2505 -1.5 -1.3 Multiple antibiotic resistance protein MarB compare
GFF4460 -1.4 -2.3 Putative inner membrane protein compare
GFF1716 -1.4 -5.7 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA compare
GFF3423 -1.4 -3.2 FIG00643583: hypothetical protein compare
GFF1901 -1.4 -3.5 Phosphate acetyltransferase (EC 2.3.1.8) compare
GFF4575 -1.4 -3.2 Magnesium and cobalt efflux protein CorC compare
GFF4770 -1.3 -1.3 transposase compare
GFF2880 -1.3 -4.6 4-alpha-L-fucosyltransferase (EC 2.4.1.-) compare
GFF2968 -1.3 -1.8 Stringent starvation protein A compare
GFF110 -1.3 -2.6 4-hydroxythreonine-4-phosphate dehydrogenase (EC 1.1.1.262) compare
GFF635 -1.3 -3.5 Tryptophanyl-tRNA synthetase (EC 6.1.1.2) compare
GFF3907 -1.3 -3.0 Imidazole glycerol phosphate synthase cyclase subunit (EC 4.1.3.-) compare
GFF4387 -1.3 -1.8 Adenine phosphoribosyltransferase (EC 2.4.2.7) compare
GFF1914 -1.2 -1.3 Cell division inhibitor compare
GFF3567 -1.2 -4.7 Pyruvate kinase (EC 2.7.1.40) compare
GFF2178 -1.2 -1.5 Thiol peroxidase, Bcp-type (EC 1.11.1.15) compare
GFF4218 -1.2 -0.9 hypothetical protein compare
GFF4643 -1.2 -1.3 hypothetical protein compare
GFF55 -1.2 -5.1 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
GFF4390 -1.2 -4.1 Recombination protein RecR compare
GFF603 -1.2 -2.5 NfuA Fe-S protein maturation compare
GFF3943 -1.2 -0.7 Propanediol dehydratase small subunit (EC 4.2.1.28) compare
GFF4732 -1.1 -1.6 SPI1-associated transcriptional regulator SprB compare
GFF4239 -1.1 -2.2 Putative inner membrane protein compare
GFF1415 -1.1 -0.9 UPF0337 protein yjbJ compare
GFF1785 -1.1 -3.1 Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon compare
GFF4409 -1.1 -4.9 YbbM seven transmembrane helix protein compare
GFF2592 -1.1 -1.5 secreted effector protein compare
GFF522 -1.1 -4.9 Low-affinity inorganic phosphate transporter compare
GFF276 -1.1 -3.1 Potassium uptake protein TrkH compare
GFF4341 -1.1 -1.5 Probable secreted protein compare
GFF2473 -1.1 -4.0 DNA recombination and repair protein RecO compare
GFF115 -1.1 -2.3 Aconitate hydratase 2 (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99) compare
GFF2541 -1.1 -2.5 putative cytoplasmic protein compare
GFF3748 -1.1 -0.7 FIG002927: hypothetical protein compare
GFF3426 -1.1 -2.0 Virulence protein MsgA compare
GFF2045 -1.1 -1.6 hypothetical protein compare
GFF2758 -1.0 -0.9 FIG01045187: hypothetical protein compare
GFF2516 -1.0 -2.8 Outer membrane protein C precursor compare
GFF4596 -1.0 -1.4 Ferric uptake regulation protein FUR compare
GFF969 -1.0 -1.5 FIG007491: hypothetical protein YeeN compare
GFF3528 -1.0 -1.7 Integration host factor alpha subunit compare
GFF3133 -1.0 -3.4 Putative cell division protein precursor compare
GFF1930 -1.0 -1.4 DedD protein compare
GFF4027 -1.0 -1.2 Flagellar biosynthesis protein FliS compare
GFF4454 -1.0 -1.0 Transcriptional regulator of fimbriae expression FimZ (LuxR/UhpA family) compare
GFF1095 -1.0 -0.8 Putative membrane protein compare
GFF1338 -1.0 -2.1 Putative outer membrane protein compare
GFF667 -1.0 -1.9 Urocanate hydratase (EC 4.2.1.49) compare
GFF2825 -1.0 -1.6 FIG00638134: hypothetical protein compare
GFF2882 -1.0 -4.3 Lipopolysaccharide biosynthesis protein RffA compare
GFF631 -1.0 -2.7 DamX, an inner membrane protein involved in bile resistance compare
GFF386 -1.0 -3.0 Lipopolysaccharide core biosynthesis protein RfaY compare
GFF991 -1.0 -1.2 hypothetical protein compare
GFF3015 -0.9 -2.2 Chromosome initiation inhibitor compare
GFF2194 -0.9 -1.3 FIG01046050: hypothetical protein compare
GFF2663 -0.9 -0.7 Thiol peroxidase, Tpx-type (EC 1.11.1.15) compare
GFF3149 -0.9 -4.4 Type I secretion outer membrane protein, TolC precursor compare
GFF4234 -0.9 -1.2 Possible transmembrane regulator compare
GFF3584 -0.9 -1.8 Type III secretion outermembrane pore forming protein (YscC,MxiD,HrcC, InvG) compare
GFF3595 -0.9 -1.3 Secretion system effector SseG compare
GFF183 -0.9 -6.0 RNA polymerase associated protein RapA (EC 3.6.1.-) compare
GFF3372 -0.9 -2.3 Phosphate:acyl-ACP acyltransferase PlsX compare
GFF387 -0.9 -2.6 Lipopolysaccharide core biosynthesis protein RfaZ compare
GFF2967 -0.9 -1.3 ClpXP protease specificity-enhancing factor / Stringent starvation protein B compare
GFF4852 -0.9 -3.4 Serine transporter compare
GFF3407 -0.9 -1.3 SifA protein compare
GFF2022 -0.9 -2.2 hypothetical protein compare
GFF3427 -0.9 -2.2 Probable lipoprotein envE precursor compare
GFF2620 -0.9 -0.8 FIG01045674: hypothetical protein compare
GFF3644 -0.9 -1.3 Electron transport complex protein RnfD compare
GFF3515 -0.9 -1.0 FIG00637864: hypothetical protein compare
GFF4772 -0.9 -0.9 hypothetical protein compare
GFF3378 -0.9 -0.9 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
GFF75 -0.9 -1.0 Major fimbrial subunit StfA compare
GFF2149 -0.9 -3.0 Malate dehydrogenase (EC 1.1.1.37) compare
GFF3322 -0.9 -2.0 Major curlin subunit precursor CsgA compare
GFF1864 -0.9 -0.7 Polymyxin resistance protein PmrM compare
GFF1804 -0.9 -2.8 Sensory histidine kinase in two-component regulatory system with RstA compare
GFF4020 -0.9 -1.5 Flagellar hook-basal body complex protein FliE compare
GFF3391 -0.9 -0.7 YcfP protein: probably an esterase that is part of a salvage cluster compare
GFF2497 -0.9 -2.0 3-hydroxypropionate dehydrogenase (EC 1.1.1.298) compare
GFF4653 -0.9 -0.9 TolA protein compare
GFF3743 -0.9 -2.0 FIG01046717: hypothetical protein compare
GFF3504 -0.8 -1.6 PTS system, cellobiose-specific IIA component (EC 2.7.1.69) compare
GFF1033 -0.8 -1.7 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
GFF4628 -0.8 -1.3 putative glycosyltransferase compare
GFF4655 -0.8 -1.3 18K peptidoglycan-associated outer membrane lipoprotein; Peptidoglycan-associated lipoprotein precursor; Outer membrane protein P6; OmpA/MotB precursor compare
GFF3608 -0.8 -3.6 Type III secretion inner membrane protein (YscQ,homologous to flagellar export components) compare
GFF399 -0.8 -1.9 FIG136845: Rhodanese-related sulfurtransferase compare
GFF3196 -0.8 -0.9 Inner membrane protein YqjE compare
GFF2496 -0.8 -2.7 Transcriptional regulator, GntR family compare
GFF985 -0.8 -1.1 Isoaspartyl dipeptidase (EC 3.4.19.5) @ Asp-X dipeptidase compare
GFF1518 -0.8 -4.2 Phosphoheptose isomerase (EC 5.3.1.-) compare
GFF2806 -0.8 -1.8 Transcriptional regulator for fatty acid degradation FadR, GntR family compare
GFF3830 -0.8 -0.5 Uncharacterized protein YehA precursor compare
GFF956 -0.8 -1.9 Gluconokinase (EC 2.7.1.12) compare
GFF3364 -0.8 -1.6 Flagellar hook-associated protein FlgL compare
GFF2527 -0.8 -1.1 Choloylglycine hydrolase (EC 3.5.1.24) compare
GFF2698 -0.8 -3.5 Exoribonuclease II (EC 3.1.13.1) compare
GFF518 -0.8 -0.9 rRNA small subunit methyltransferase J compare
GFF4367 -0.8 -2.1 Nitrogen regulatory protein P-II, glnK compare
GFF2470 -0.8 -0.9 4Fe-4S ferredoxin, iron-sulfur binding compare
GFF539 -0.8 -2.1 Putative inner membrane protein compare
GFF2989 -0.8 -3.2 Single-stranded-DNA-specific exonuclease RecJ (EC 3.1.-.-) compare
GFF451 -0.8 -3.0 Mobile element protein compare
GFF3298 -0.8 -1.4 FIG01049236: hypothetical protein compare
GFF2166 -0.8 -3.4 Exopolyphosphatase (EC 3.6.1.11) compare
GFF1662 -0.8 -2.0 Chemotaxis response - phosphatase CheZ compare
GFF356 -0.8 -1.2 'tRNA (guanosine(18)-2'-O)-methyltransferase (EC 2.1.1.34)' transl_table=11 compare
GFF4835 -0.8 -1.1 ParE toxin protein compare
GFF4290 -0.8 -2.8 DNA recombination-dependent growth factor C compare
GFF265 -0.7 -3.7 Twin-arginine translocation protein TatC compare
GFF1109 -0.7 -1.1 Putative LysR family transcriptional regulator compare
GFF3632 -0.7 -1.3 Transcriptional regulator SlyA compare
GFF3864 -0.7 -2.2 Putative capsular polysaccharide transport protein YegH compare
GFF3583 -0.7 -1.0 Type III secretion protein SsaB compare
GFF4175 -0.7 -3.1 Uncharacterized protein YfiR precursor compare
GFF1747 -0.7 -0.9 putative inner membrane protein compare
GFF2160 -0.7 -1.6 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 compare
GFF2280 -0.7 -1.9 Copper-sensing two-component system response regulator CpxR compare
GFF773 -0.7 -0.8 probable lipoprotein compare
GFF905 -0.7 -2.3 Soluble cytochrome b562 compare
GFF2202 -0.7 -1.5 hypothetical protein compare
GFF4192 -0.7 -1.6 DNA-binding protein HU-alpha compare
GFF2119 -0.7 -1.0 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
GFF1271 -0.7 -4.2 GtgA compare
GFF1449 -0.7 -2.2 CidA-associated membrane protein CidB compare
GFF4380 -0.7 -3.0 Membrane fusion protein of RND family multidrug efflux pump compare
GFF2528 -0.7 -2.2 Hexuronate utilization operon transcriptional repressor ExuR compare
GFF831 -0.7 -2.3 Nitrite-sensitive transcriptional repressor NsrR compare
GFF3511 -0.7 -1.2 Membrane-bound metal-dependent hydrolase YdjM, induced during SOS response compare
GFF1119 -0.7 -2.8 Na+/H+ antiporter NhaA type compare
GFF4370 -0.7 -2.7 Glycoprotein-polysaccharide metabolism compare
GFF218 -0.7 -1.4 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.61) compare
GFF648 -0.7 -1.6 Phosphoglycerate mutase (EC 5.4.2.1) compare
GFF325 -0.7 -1.5 PTS system, gluconate-specific IIB component (EC 2.7.1.69) compare
GFF3437 -0.7 -2.2 Putative outer membrane lipoprotein compare
GFF2083 -0.7 -1.3 Ethanolamine utilization protein EutQ compare


Specific Phenotypes

None in this experiment

For Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 in phage experiments

For phage phi19h1_phage across organisms