Experiment set6IT012 for Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Compare to:

Ffm_phage 10 MOI; agar plate assay

200 most important genes:

  gene name fitness t score description  
GFF2347 -8.2 -4.9 Hydrogen peroxide-inducible genes activator compare
GFF387 -8.0 -2.3 Lipopolysaccharide core biosynthesis protein RfaZ compare
GFF2475 -7.7 -2.3 Ribonuclease III (EC 3.1.26.3) compare
GFF3712 -7.1 -2.9 Cyclic AMP receptor protein compare
GFF603 -6.9 -2.6 NfuA Fe-S protein maturation compare
GFF2392 -6.8 -1.2 Peptide deformylase (EC 3.5.1.88) compare
GFF384 -6.8 -3.4 UDP-glucose:(glucosyl)lipopolysaccharide alpha-1,3-glucosyltransferase WaaO (EC 2.4.1.-) compare
GFF3890 -6.6 -1.9 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13) compare
GFF3888 -6.5 -2.9 dTDP-4-dehydrorhamnose reductase (EC 1.1.1.133) compare
GFF121 -6.0 -2.8 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.12) compare
GFF388 -6.0 -10.7 Lipopolysaccharide 1,2-N-acetylglucosaminetransferase (EC 2.4.1.56) compare
GFF2690 -5.9 -1.7 Peptide transport system permease protein SapC compare
GFF1921 -5.9 -2.0 3-polyprenyl-4-hydroxybenzoate carboxy-lyase UbiX (EC 4.1.1.-) compare
GFF1079 -5.9 -1.0 Homoserine kinase (EC 2.7.1.39) compare
GFF390 -5.8 -2.2 Lipopolysaccharide heptosyltransferase I (EC 2.4.1.-) compare
GFF360 -5.7 -1.0 hypothetical protein compare
GFF1634 -5.7 -2.7 Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase (EC 2.3.1.-) compare
GFF389 -5.7 -2.1 Oligosaccharide repeat unit polymerase Wzy; O-antigen ligase compare
GFF355 -5.6 -2.1 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
GFF1716 -5.5 -7.6 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA compare
GFF267 -5.2 -5.7 Transcriptional activator RfaH compare
GFF122 -5.2 -8.7 Pyruvate dehydrogenase E1 component (EC 1.2.4.1) compare
GFF276 -5.2 -6.2 Potassium uptake protein TrkH compare
GFF3166 -5.2 -3.6 ADP-heptose synthase (EC 2.7.-.-) / D-glycero-beta-D-manno-heptose 7-phosphate kinase compare
GFF236 -5.1 -0.9 FIG00545237: hypothetical protein compare
GFF2216 -5.0 -9.9 DNA polymerase I (EC 2.7.7.7) compare
GFF20 -5.0 -7.6 D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase (EC 3.1.1.-) compare
GFF2991 -4.8 -2.3 Tyrosine recombinase XerD compare
GFF392 -4.7 -2.1 ADP-L-glycero-D-manno-heptose-6-epimerase (EC 5.1.3.20) compare
GFF381 -4.7 -7.3 Lipopolysaccharide core biosynthesis protein WaaP (EC 2.7.-.-), heptosyl-I-kinase compare
GFF4061 -4.6 -0.8 putative periplasmic protein compare
GFF391 -4.6 -2.0 ADP-heptose--lipooligosaccharide heptosyltransferase II (EC 2.4.1.-) compare
GFF1571 -4.6 -0.8 FIG00638334: hypothetical protein compare
GFF1750 -4.5 -3.8 GTPase and tRNA-U34 5-formylation enzyme TrmE compare
GFF2692 -4.5 -4.1 Peptide transport system ATP-binding protein SapF compare
GFF2389 -4.5 -1.7 Trk system potassium uptake protein TrkA compare
GFF2946 -4.4 -4.1 RNA polymerase sigma-54 factor RpoN compare
GFF1303 -4.4 -1.3 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
GFF4639 -4.4 -2.3 2-oxoglutarate dehydrogenase E1 component (EC 1.2.4.2) compare
GFF4355 -4.3 -1.0 ATP-dependent protease La (EC 3.4.21.53) Type I compare
GFF4635 -4.2 -2.3 Succinate dehydrogenase cytochrome b-556 subunit compare
GFF2173 -4.1 -4.4 Chromosomal replication initiator protein DnaA compare
GFF1553 -3.9 -0.9 FIG01046564: hypothetical protein compare
GFF2276 -3.9 -1.3 Manganese superoxide dismutase (EC 1.15.1.1) compare
GFF2430 -3.8 -1.3 Ferredoxin, 2Fe-2S compare
GFF3943 -3.8 -0.9 Propanediol dehydratase small subunit (EC 4.2.1.28) compare
GFF2047 -3.7 -9.3 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
GFF520 -3.7 -2.3 Universal stress protein A compare
GFF1312 -3.6 -2.8 'Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-)' transl_table=11 compare
GFF55 -3.6 -8.3 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
GFF3667 -3.6 -1.4 Cytidylate kinase (EC 2.7.4.25) compare
GFF635 -3.6 -4.1 Tryptophanyl-tRNA synthetase (EC 6.1.1.2) compare
GFF1032 -3.5 -0.8 DNA polymerase III psi subunit (EC 2.7.7.7) compare
GFF4596 -3.4 -2.3 Ferric uptake regulation protein FUR compare
GFF4454 -3.4 -1.1 Transcriptional regulator of fimbriae expression FimZ (LuxR/UhpA family) compare
GFF1934 -3.3 -3.4 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
GFF1256 -3.3 -4.5 Chromosome (plasmid) partitioning protein ParA compare
GFF4027 -3.2 -1.1 Flagellar biosynthesis protein FliS compare
GFF4652 -3.1 -2.8 Tol biopolymer transport system, TolR protein compare
GFF4353 -3.0 -2.8 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
GFF4615 -3.0 -1.0 FIG137478: Hypothetical protein YbgI compare
GFF2477 -3.0 -5.7 Translation elongation factor LepA compare
GFF1499 -2.9 -3.0 Ribosome-binding factor A compare
GFF190 -2.8 -4.6 SSU rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase (EC 2.1.1.182) compare
GFF3772 -2.8 -1.6 1-phosphofructokinase (EC 2.7.1.56) compare
GFF4341 -2.8 -1.4 Probable secreted protein compare
GFF2348 -2.8 -4.1 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
GFF3862 -2.7 -2.9 Deoxycytidine triphosphate deaminase (EC 3.5.4.13) compare
GFF824 -2.6 -2.3 tRNA dimethylallyltransferase (EC 2.5.1.75) compare
GFF4601 -2.6 -5.4 Phosphoglucomutase (EC 5.4.2.2) compare
GFF2689 -2.6 -2.5 Peptide transport system permease protein SapB compare
GFF3901 -2.6 -2.1 Phosphomannomutase (EC 5.4.2.8) compare
GFF380 -2.6 -5.4 UDP-glucose:(heptosyl) LPS alpha1,3-glucosyltransferase WaaG (EC 2.4.1.-) compare
GFF630 -2.6 -6.5 3-dehydroquinate synthase (EC 4.2.3.4) compare
GFF4653 -2.5 -1.9 TolA protein compare
GFF4642 -2.5 -0.8 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) compare
GFF4655 -2.5 -2.0 18K peptidoglycan-associated outer membrane lipoprotein; Peptidoglycan-associated lipoprotein precursor; Outer membrane protein P6; OmpA/MotB precursor compare
GFF4636 -2.4 -3.4 Succinate dehydrogenase hydrophobic membrane anchor protein compare
GFF1615 -2.4 -1.0 phage-tail assembly-like protein compare
GFF1768 -2.4 -0.8 hypothetical protein compare
GFF633 -2.3 -3.2 Ribulose-phosphate 3-epimerase (EC 5.1.3.1) compare
GFF2063 -2.3 -0.9 Inner membrane protein YfeZ compare
GFF3748 -2.3 -0.8 FIG002927: hypothetical protein compare
GFF4288 -2.3 -5.1 AroM protein compare
GFF230 -2.3 -6.7 Adenylate cyclase (EC 4.6.1.1) compare
GFF192 -2.3 -4.8 'Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41)' transl_table=11 compare
GFF2553 -2.3 -1.1 Osmotically inducible protein C compare
GFF2431 -2.3 -2.7 Chaperone protein HscA compare
GFF4641 -2.2 -2.2 Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5) compare
GFF4145 -2.2 -0.9 hypothetical protein compare
GFF3548 -2.2 -3.3 3-dehydroquinate dehydratase I (EC 4.2.1.10) compare
GFF3558 -2.2 -1.4 Iron binding protein SufA for iron-sulfur cluster assembly compare
GFF2397 -2.2 -5.6 Shikimate 5-dehydrogenase I alpha (EC 1.1.1.25) compare
GFF3244 -2.1 -2.1 hypothetical protein compare
GFF2220 -2.1 -6.3 Nitrogen regulation protein NR(I) compare
GFF4182 -2.1 -5.4 Ribosomal large subunit pseudouridine synthase D (EC 4.2.1.70) compare
GFF113 -2.1 -2.2 FIG01045153: hypothetical protein compare
GFF2160 -2.1 -1.8 'Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) / CBS domain' transl_table=11 compare
GFF3555 -2.0 -0.8 1,4-dihydroxy-2-naphthoyl-CoA hydrolase (EC 3.1.2.28) in menaquinone biosynthesis compare
GFF876 -2.0 -8.8 UPF0131 protein YtfP compare
GFF2992 -2.0 -5.6 Flavodoxin 2 compare
GFF1930 -2.0 -1.5 DedD protein compare
GFF1659 -2.0 -3.0 Flagellar protein FlhE compare
GFF4637 -2.0 -8.4 Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) compare
GFF510 -1.9 -2.0 kinase (ribokinase family) compare
GFF1901 -1.9 -3.6 Phosphate acetyltransferase (EC 2.3.1.8) compare
GFF2784 -1.9 -2.1 GTP-binding and nucleic acid-binding protein YchF compare
GFF4316 -1.9 -1.1 hypothetical protein compare
GFF2583 -1.9 -0.8 FIG00638150: hypothetical protein compare
GFF1472 -1.9 -0.9 Transcriptional regulator of catabolic arginine decarboxylase (adiA) compare
GFF1090 -1.8 -1.8 Chaperone protein DnaJ compare
GFF1597 -1.8 -9.5 Glutamate--cysteine ligase (EC 6.3.2.2) compare
GFF3324 -1.8 -0.6 putative periplasmic protein compare
GFF1334 -1.8 -0.7 Uncharacterized protein YohL compare
GFF4354 -1.8 -2.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
GFF4638 -1.8 -2.8 Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) compare
GFF238 -1.8 -1.9 Protein of unknown function DUF484 compare
GFF379 -1.8 -5.9 Lipopolysaccharide heptosyltransferase III (EC 2.4.1.-) compare
GFF2948 -1.8 -2.7 PTS system nitrogen-specific IIA component, PtsN compare
GFF2398 -1.8 -0.8 FIG00640156: hypothetical protein compare
GFF1900 -1.8 -5.9 Acetate kinase (EC 2.7.2.1) compare
GFF2881 -1.8 -4.8 WzxE protein compare
GFF3518 -1.8 -1.0 putative outer membrane protein compare
GFF4364 -1.8 -2.4 Putative HTH-type transcriptional regulator ybaO compare
GFF2269 -1.8 -1.0 hypothetical protein compare
GFF1884 -1.8 -0.9 NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3) compare
GFF3341 -1.7 -1.2 DNA-damage-inducible protein I compare
GFF3320 -1.7 -1.1 Transcriptional regulator CsgD for 2nd curli operon compare
GFF828 -1.7 -2.5 HflC protein compare
GFF829 -1.7 -0.6 Putative inner membrane protein YjeT (clustered with HflC) compare
GFF4158 -1.7 -1.0 tmRNA-binding protein SmpB compare
GFF3377 -1.7 -3.2 3-oxoacyl-[acyl-carrier-protein] synthase, KASII (EC 2.3.1.41) compare
GFF522 -1.7 -4.9 Low-affinity inorganic phosphate transporter compare
GFF2221 -1.7 -5.5 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
GFF1304 -1.6 -1.0 FIG004136: Prepilin peptidase dependent protein C precursor compare
GFF3715 -1.6 -2.4 FIG01199774: hypothetical protein compare
GFF3149 -1.6 -5.9 Type I secretion outer membrane protein, TolC precursor compare
GFF4654 -1.6 -2.9 tolB protein precursor, periplasmic protein involved in the tonb-independent uptake of group A colicins compare
GFF2119 -1.6 -0.9 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
GFF4096 -1.6 -0.8 FIG01047254: hypothetical protein compare
GFF3461 -1.6 -0.6 hypothetical protein compare
GFF3659 -1.6 -1.4 FIG01045244: hypothetical protein compare
GFF632 -1.6 -3.0 Methyl-directed repair DNA adenine methylase (EC 2.1.1.72) compare
GFF87 -1.6 -1.2 C4-type zinc finger protein, DksA/TraR family compare
GFF3039 -1.6 -2.3 Putative outer membrane lipoprotein compare
GFF2773 -1.6 -2.9 Protein-N(5)-glutamine methyltransferase PrmC, methylates polypeptide chain release factors RF1 and RF2 compare
GFF4060 -1.6 -0.7 putative cytoplasmic protein compare
GFF261 -1.6 -1.0 Protein YigP (COG3165) clustered with ubiquinone biosynthetic genes compare
GFF3644 -1.5 -1.7 Electron transport complex protein RnfD compare
GFF2808 -1.5 -4.1 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
GFF701 -1.5 -0.7 Hypothetical Zinc-finger containing protein compare
GFF2148 -1.5 -1.1 Arginine pathway regulatory protein ArgR, repressor of arg regulon compare
GFF2434 -1.5 -0.6 Iron-sulfur cluster assembly scaffold protein IscU compare
GFF2478 -1.5 -0.8 leucine-rich repeat protein compare
GFF1239 -1.5 -1.2 Gifsy-2 prophage lysozyme( EC:3.2.1.17 ) compare
GFF1519 -1.4 -1.8 Predicted endonuclease distantly related to archaeal Holliday junction resolvase compare
GFF2433 -1.4 -2.7 Iron binding protein IscA for iron-sulfur cluster assembly compare
GFF827 -1.4 -3.5 HflK protein compare
GFF969 -1.4 -1.0 FIG007491: hypothetical protein YeeN compare
GFF4305 -1.4 -2.6 tRNA-guanine transglycosylase (EC 2.4.2.29) compare
GFF518 -1.4 -0.7 rRNA small subunit methyltransferase J compare
GFF341 -1.4 -0.6 RmbA compare
GFF265 -1.4 -3.1 Twin-arginine translocation protein TatC compare
GFF3117 -1.4 -1.3 Biopolymer transport protein ExbD/TolR compare
GFF4600 -1.4 -1.8 SeqA protein, negative modulator of initiation of replication compare
GFF1168 -1.4 -1.1 IncF plasmid conjugative transfer protein TrbI compare
GFF4138 -1.4 -1.2 PTS system, glucitol/sorbitol-specific IIA component (EC 2.7.1.69) compare
GFF4317 -1.4 -3.1 Ribonucleotide reductase transcriptional regulator NrdR compare
GFF4071 -1.4 -2.5 FIG074102: hypothetical protein compare
GFF4406 -1.4 -1.3 Putative activity regulator of membrane protease YbbK compare
GFF826 -1.3 -2.5 GTP-binding protein HflX compare
GFF2994 -1.3 -0.9 YgfY COG2938 compare
GFF2700 -1.3 -0.7 FIG01045186: hypothetical protein compare
GFF2470 -1.3 -0.7 4Fe-4S ferredoxin, iron-sulfur binding compare
GFF3632 -1.3 -1.6 Transcriptional regulator SlyA compare
GFF2279 -1.3 -3.3 Copper sensory histidine kinase CpxA compare
GFF2825 -1.3 -1.4 FIG00638134: hypothetical protein compare
GFF707 -1.3 -1.6 Non-specific DNA-binding protein Dps / Iron-binding ferritin-like antioxidant protein / Ferroxidase (EC 1.16.3.1) compare
GFF2222 -1.3 -2.9 Glutamine synthetase type I (EC 6.3.1.2) compare
GFF4249 -1.3 -1.5 Cu(I)-responsive transcriptional regulator compare
GFF417 -1.3 -4.3 Mannitol-1-phosphate 5-dehydrogenase (EC 1.1.1.17) compare
GFF1864 -1.3 -0.6 Polymyxin resistance protein PmrM compare
GFF4343 -1.3 -1.6 Cytochrome O ubiquinol oxidase subunit IV (EC 1.10.3.-) compare
GFF4644 -1.3 -0.9 hypothetical protein compare
GFF4647 -1.3 -4.0 Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) compare
GFF3058 -1.3 -1.5 Radical SAM family enzyme, similar to coproporphyrinogen III oxidase, oxygen-independent, clustered with nucleoside-triphosphatase RdgB compare
GFF4344 -1.3 -2.6 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) compare
GFF4700 -1.3 -1.1 Glucitol operon activator protein compare
GFF1678 -1.3 -1.5 Ferritin-like protein 2 compare
GFF3582 -1.3 -2.0 Secretion system regulator: Sensor component (EC 2.7.3.-) (EC 2.7.1.40) compare
GFF2098 -1.3 -1.4 Thioredoxin 2 (EC 1.8.1.8) compare
GFF734 -1.2 -0.9 putative cytoplasmic protein compare
GFF115 -1.2 -2.3 Aconitate hydratase 2 (EC 4.2.1.3) @ 2-methylisocitrate dehydratase (EC 4.2.1.99) compare
GFF386 -1.2 -2.8 Lipopolysaccharide core biosynthesis protein RfaY compare
GFF2688 -1.2 -3.1 Peptide transport periplasmic protein SapA compare
GFF3685 -1.2 -3.4 Aspartate aminotransferase (EC 2.6.1.1) compare
GFF1937 -1.2 -3.2 Cell division protein compare
GFF4513 -1.2 -1.4 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) compare
GFF4522 -1.2 -1.0 Regulator of nucleoside diphosphate kinase compare
GFF1888 -1.2 -1.2 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) compare


Specific Phenotypes

None in this experiment

For Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 in phage experiments

For phage Ffm_phage across organisms