Experiment set69S571 for Escherichia coli BW25113

Compare to:

TP11

200 most important genes:

  gene name fitness t score description  
b0053 surA -2.6 -3.0 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b0088 murD -2.2 -2.4 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b2286 nuoC -2.1 -5.6 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b1984 asnW -2.0 -1.6 tRNA-Asn (NCBI) compare
b0049 apaH -2.0 -3.0 diadenosinetetraphosphatase (NCBI) compare
b2282 nuoH -2.0 -3.4 NADH dehydrogenase subunit H (NCBI) compare
b2168 fruK -1.9 -1.7 1-phosphofructokinase (NCBI) compare
b3621 rfaC -1.8 -5.1 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b2284 nuoF -1.8 -4.6 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b4201 priB -1.8 -3.1 primosomal replication protein N (NCBI) compare
b2318 truA -1.7 -3.5 tRNA pseudouridine synthase A (NCBI) compare
b2287 nuoB -1.7 -3.9 NADH dehydrogenase subunit B (NCBI) compare
b2576 srmB -1.7 -3.6 ATP-dependent RNA helicase (NCBI) compare
b4702 mgtL -1.7 -2.2 regulatory leader peptide for mgtA (NCBI) compare
b0888 trxB -1.7 -3.6 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b3778 rep -1.7 -7.3 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b4178 yjeB -1.7 -5.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b4513 kdpF -1.7 -2.4 potassium ion accessory transporter subunit (NCBI) compare
b2518 ndk -1.7 -2.6 nucleoside diphosphate kinase (NCBI) compare
b2281 nuoI -1.6 -2.8 NADH dehydrogenase subunit I (NCBI) compare
b0080 fruR -1.6 -5.4 DNA-binding transcriptional dual regulator (NCBI) compare
b1293 sapB -1.6 -2.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1712 ihfA -1.6 -2.0 integration host factor subunit alpha (NCBI) compare
b2283 nuoG -1.5 -6.3 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b4699 fnrS -1.5 -0.9 FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) compare
b3811 xerC -1.5 -1.7 site-specific tyrosine recombinase XerC (NCBI) compare
b2699 recA -1.5 -1.0 recombinase A (NCBI) compare
b2278 nuoL -1.5 -7.2 NADH dehydrogenase subunit L (NCBI) compare
b2808 gcvA -1.5 -4.0 DNA-binding transcriptional dual regulator (NCBI) compare
b2277 nuoM -1.5 -5.2 NADH dehydrogenase subunit M (NCBI) compare
b1236 galU -1.5 -4.2 glucose-1-phosphate uridylyltransferase (NCBI) compare
b2906 visC -1.5 -5.9 hypothetical protein (NCBI) compare
b4535 yniD -1.5 -1.6 predicted protein (RefSeq) compare
b3619 rfaD -1.4 -3.0 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1358 ydaT -1.4 -1.3 Rac prophage; predicted protein (NCBI) compare
b1290 sapF -1.4 -1.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3169 nusA -1.4 -3.1 transcription elongation factor NusA (NCBI) compare
b3636 rpmG -1.4 -1.7 50S ribosomal protein L33 (NCBI) compare
b2276 nuoN -1.3 -4.4 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b4592 yccB -1.3 -1.4 hypothetical protein (RefSeq) compare
b2279 nuoK -1.3 -1.9 NADH dehydrogenase subunit K (NCBI) compare
b3052 rfaE -1.3 -4.5 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1855 lpxM -1.3 -4.0 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b2280 nuoJ -1.3 -4.5 NADH dehydrogenase subunit J (NCBI) compare
b2934 cmtB -1.3 -0.8 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b0247 ykfG -1.2 -1.5 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b4163 glyV -1.2 -1.7 tRNA-Gly (NCBI) compare
b0437 clpP -1.2 -4.6 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b2498 upp -1.2 -2.3 uracil phosphoribosyltransferase (VIMSS) compare
b3728 pstS -1.2 -1.8 phosphate transporter subunit (NCBI) compare
b2804 fucU -1.2 -2.8 L-fucose mutarotase (NCBI) compare
b3706 trmE -1.2 -2.6 tRNA modification GTPase (NCBI) compare
b3026 qseC -1.2 -3.2 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1307 pspD -1.2 -2.0 peripheral inner membrane phage-shock protein (NCBI) compare
b1545 pinQ -1.2 -0.5 Qin prophage; predicted site-specific recombinase (NCBI) compare
b2620 smpB -1.2 -1.3 SsrA-binding protein (NCBI) compare
b0740 tolB -1.1 -3.2 translocation protein TolB precursor (NCBI) compare
b1382 ynbE -1.1 -1.4 predicted lipoprotein (NCBI) compare
b0729 sucD -1.1 -2.8 succinyl-CoA synthetase subunit alpha (NCBI) compare
b3493 pitA -1.1 -5.1 phosphate transporter, low-affinity (NCBI) compare
b0890 ftsK -1.1 -3.2 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b4146 yjeK -1.1 -1.5 predicted lysine aminomutase (NCBI) compare
b4042 dgkA -1.1 -1.3 diacylglycerol kinase (NCBI) compare
b4179 vacB -1.1 -4.4 putative enzyme (VIMSS) compare
b0720 gltA -1.1 -5.2 citrate synthase (NCBI) compare
b1961 dcm -1.1 -1.5 DNA cytosine methylase (NCBI) compare
b3620 rfaF -1.1 -3.9 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b2567 rnc -1.1 -1.0 ribonuclease III (NCBI) compare
b2830 nudH -1.1 -1.2 dinucleoside polyphosphate hydrolase (NCBI) compare
b1685 ydiH -1.1 -1.5 predicted protein (RefSeq) compare
b1084 rne -1.1 -4.3 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b1291 sapD -1.1 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2528 iscA -1.1 -1.5 iron-sulfur cluster assembly protein (NCBI) compare
b1383 ydbL -1.1 -2.7 orf, hypothetical protein (VIMSS) compare
b3162 deaD -1.1 -3.3 inducible ATP-independent RNA helicase (VIMSS) compare
b0222 lpcA -1.1 -2.2 phosphoheptose isomerase (NCBI) compare
b0200 gmhB -1.0 -0.9 hypothetical protein (NCBI) compare
b3871 bipA -1.0 -6.1 GTP-binding protein (NCBI) compare
b3075 ebgR -1.0 -3.3 DNA-binding transcriptional repressor (NCBI) compare
b4441 glmY -1.0 -1.5 sRNA activator of glmS mRNA (RefSeq) compare
b1185 dsbB -1.0 -2.5 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b0051 ksgA -1.0 -3.3 dimethyladenosine transferase (NCBI) compare
b3766 ilvL -1.0 -2.5 ilvG operon leader peptide (NCBI) compare
b0726 sucA -1.0 -2.5 alpha-ketoglutarate decarboxylase (NCBI) compare
b1400 paaY -1.0 -2.5 predicted hexapeptide repeat acetyltransferase (NCBI) compare
b4171 miaA -1.0 -2.3 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b0722 sdhD -1.0 -2.8 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b1536 ydeI -1.0 -0.6 hypothetical protein (NCBI) compare
b3962 udhA -1.0 -4.3 putative oxidoreductase (VIMSS) compare
b0149 mrcB -1.0 -7.1 penicillin-binding protein 1b (NCBI) compare
b2935 tktA -1.0 -1.4 transketolase 1, thiamin-binding (NCBI) compare
b1269 rluB -0.9 -2.3 23S rRNA pseudouridylate synthase (NCBI) compare
b3816 corA -0.9 -4.7 magnesium/nickel/cobalt transporter (NCBI) compare
b1969 yedW -0.9 -3.0 putative 2-component transcriptional regulator (VIMSS) compare
b3290 trkA -0.9 -1.4 potassium transporter peripheral membrane component (NCBI) compare
b0502 ylbG -0.9 -2.3 no description compare
b3870 glnA -0.9 -2.3 glutamine synthetase (NCBI) compare
b3741 gidA -0.9 -2.2 glucose-inhibited division protein A (NCBI) compare
b3181 greA -0.9 -3.6 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b0430 cyoC -0.9 -3.2 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b0739 tolA -0.9 -2.2 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1575 dicB -0.9 -1.5 Qin prophage; cell division inhibition protein (NCBI) compare
b3979 thrT -0.9 -0.4 tRNA-Thr (NCBI) compare
b0505 allA -0.9 -2.7 ureidoglycolate hydrolase (NCBI) compare
b3198 kdsC -0.9 -2.0 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b3205 yhbJ -0.9 -2.5 hypothetical protein (NCBI) compare
b4426 isrA -0.9 -1.6 unknown RNA (NCBI) compare
b1667 ydhR -0.9 -2.0 hypothetical protein (NCBI) compare
b3035 tolC -0.9 -4.4 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b0438 clpX -0.9 -3.7 ATP-dependent protease ATP-binding subunit (NCBI) compare
b2990 hybG -0.9 -1.5 hydrogenase 2 accessory protein (NCBI) compare
b3426 glpD -0.9 -2.0 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b1548 nohA -0.9 -1.0 Qin prophage; predicted packaging protein (RefSeq) compare
b3414 gntY -0.9 -3.5 predicted gluconate transport associated protein (NCBI) compare
b2947 gshB -0.8 -2.7 glutathione synthetase (NCBI) compare
b4655 ythA -0.8 -1.1 expressed protein (RefSeq) compare
b1505 ydeT -0.8 -0.8 hypothetical protein (RefSeq) compare
b3002 yqhA -0.8 -1.9 hypothetical protein (NCBI) compare
b0741 pal -0.8 -2.2 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1540 ydfH -0.8 -1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b3631 rfaG -0.8 -6.1 glucosyltransferase I (NCBI) compare
b3849 trkH -0.8 -5.6 potassium transporter (NCBI) compare
b2025 hisF -0.8 -2.9 imidazole glycerol phosphate synthase subunit HisF (NCBI) compare
b0721 sdhC -0.8 -3.0 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b2569 lepA -0.8 -2.5 GTP-binding protein LepA (NCBI) compare
b3164 pnp -0.8 -1.7 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b0471 ybaB -0.8 -2.2 hypothetical protein (NCBI) compare
b4406 yaeP -0.8 -1.5 hypothetical protein (NCBI) compare
b3999 yjaG -0.8 -2.8 hypothetical protein (NCBI) compare
b0018 mokC -0.8 -1.0 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b3791 rffA -0.8 -4.0 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b4701 sokX -0.8 -0.5 sok-related sRNA, function unknown (RefSeq) compare
b3916 pfkA -0.8 -1.4 6-phosphofructokinase (NCBI) compare
b4648 ysaC -0.8 -1.6 no description compare
b0386 proC -0.8 -3.0 pyrroline-5-carboxylate reductase (NCBI) compare
b4494 arpB -0.8 -1.5 no description compare
b3545 proK -0.8 -1.0 tRNA-Pro (NCBI) compare
b1105 ycfM -0.8 -2.1 predicted outer membrane lipoprotein (NCBI) compare
b4402 yjjY -0.8 -0.8 hypothetical protein (NCBI) compare
b1370 insH-5 -0.7 -0.9 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b0723 sdhA -0.7 -4.6 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b2289 lrhA -0.7 -4.9 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) compare
b3613 yibP -0.7 -2.3 putative membrane protein (VIMSS) compare
b2824 ygdB -0.7 -2.0 orf, hypothetical protein (VIMSS) compare
b2679 proX -0.7 -2.9 glycine betaine transporter subunit (NCBI) compare
b3844 fre -0.7 -3.1 NAD(P)H-flavin reductase (NCBI) compare
b0658 ybeX -0.7 -0.5 predicteed ion transport (NCBI) compare
b3623 rfaK -0.7 -1.3 lipopolysaccharide core biosynthesis (NCBI) compare
b2479 gcvR -0.7 -2.6 transcriptional regulation of gcv operon (VIMSS) compare
b1282 yciH -0.7 -2.3 orf, hypothetical protein (VIMSS) compare
b2684 mprA -0.7 -2.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux (NCBI) compare
b1160 elbA -0.7 -0.6 hypothetical protein (NCBI) compare
b0428 cyoE -0.7 -3.7 protoheme IX farnesyltransferase (NCBI) compare
b1921 fliZ -0.7 -1.8 orf, hypothetical protein (VIMSS) compare
b1533 ydeD -0.7 -1.6 orf, hypothetical protein (VIMSS) compare
b0082 mraW -0.7 -2.0 S-adenosyl-methyltransferase (NCBI) compare
b1778 yeaA -0.7 -1.2 methionine sulfoxide reductase B (NCBI) compare
b1497 b1497 -0.7 -0.4 putative enzyme (VIMSS) compare
b3806 cyaA -0.7 -2.4 adenylate cyclase (NCBI) compare
b1524 yneH -0.7 -0.6 predicted glutaminase (NCBI) compare
b1482 osmC -0.7 -1.1 osmotically inducible, stress-inducible membrane protein (NCBI) compare
b3742 mioC -0.7 -2.5 flavodoxin (NCBI) compare
b1583 ynfB -0.7 -1.6 hypothetical protein (NCBI) compare
b3389 aroB -0.7 -4.2 3-dehydroquinate synthase (NCBI) compare
b1124 potC -0.7 -2.2 spermidine/putrescine ABC transporter membrane protein (NCBI) compare
b2784 relA -0.6 -4.3 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b1235 rssB -0.6 -3.5 response regulator of RpoS (NCBI) compare
b3781 trxA -0.6 -2.0 thioredoxin 1 (VIMSS) compare
b2426 ucpA -0.6 -1.5 putative oxidoreductase (VIMSS) compare
b3860 dsbA -0.6 -3.8 periplasmic protein disulfide isomerase I (NCBI) compare
b4414 tff -0.6 -2.0 unknown RNA (NCBI) compare
b4375 prfC -0.6 -2.2 peptide chain release factor 3 (NCBI) compare
b0728 sucC -0.6 -2.3 succinyl-CoA synthetase subunit beta (NCBI) compare
b4589 ylcI -0.6 -1.3 hypothetical protein (RefSeq) compare
b3236 mdh -0.6 -3.6 malate dehydrogenase (NCBI) compare
b3935 priA -0.6 -1.5 primosome assembly protein PriA (NCBI) compare
b0580 ybdJ -0.6 -1.4 predicted inner membrane protein (NCBI) compare
b3281 aroE -0.6 -4.6 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b3040 ygiE -0.6 -4.0 zinc transporter ZupT (NCBI) compare
b2363 yfdT -0.6 -1.2 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b3649 rpoZ -0.6 -1.7 DNA-directed RNA polymerase subunit omega (NCBI) compare
b3911 cpxA -0.6 -4.3 two-component sensor protein (NCBI) compare
b1580 rspB -0.6 -2.7 predicted oxidoreductase, Zn-dependent and NAD(P)-binding (NCBI) compare
b0439 lon -0.6 -2.3 DNA-binding ATP-dependent protease La (NCBI) compare
b1576 ydfD -0.6 -0.3 Qin prophage; predicted protein (NCBI) compare
b3839 tatC -0.6 -2.9 TatABCE protein translocation system subunit (NCBI) compare
b3099 yqjE -0.6 -2.1 conserved inner membrane protein (NCBI) compare
b0928 aspC -0.6 -2.9 aspartate aminotransferase, PLP-dependent (NCBI) compare
b3867 hemN -0.6 -4.0 O2-independent coproporphyrinogen III oxidase (VIMSS) compare
b4319 fimG -0.6 -3.8 minor component of type 1 fimbriae (NCBI) compare
b4541 yehK -0.6 -2.0 hypothetical protein (NCBI) compare
b4614 sokA -0.6 -1.5 no description compare
b1591 b1591 -0.6 -1.3 putative oxidoreductase component (VIMSS) compare
b4481 rffT -0.6 -2.5 4-alpha-L-fucosyltransferase (NCBI) compare
b2822 recC -0.6 -1.6 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b0738 tolR -0.6 -1.3 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1442 ydcU -0.6 -2.4 predicted spermidine/putrescine transporter subunit (NCBI) compare
b2506 yfgI -0.6 -1.1 hypothetical protein (NCBI) compare
b1790 yeaM -0.6 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b0866 ybjQ -0.6 -0.6 hypothetical protein (NCBI) compare


Specific Phenotypes

None in this experiment

For Escherichia coli BW25113 in phage experiments

For phage MOI 10 across organisms