| | gene | name | fitness | t score | description | |
|---|
| b1261 | trpB | -6.8 | -4.7 | tryptophan synthase subunit beta (NCBI) | compare |
| b1260 | trpA | -6.8 | -5.7 | tryptophan synthase subunit alpha (NCBI) | compare |
| b0073 | leuB | -6.4 | -7.6 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b1192 | ldcA | -6.4 | -11.2 | L,D-carboxypeptidase A (NCBI) | compare |
| b2021 | hisC | -6.3 | -6.2 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b2312 | purF | -5.7 | -6.8 | amidophosphoribosyltransferase (NCBI) | compare |
| b4005 | purD | -5.7 | -9.5 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b0004 | thrC | -5.7 | -8.7 | threonine synthase (NCBI) | compare |
| b1281 | pyrF | -5.7 | -5.5 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b2476 | purC | -5.6 | -4.6 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b3774 | ilvC | -5.6 | -17.5 | ketol-acid reductoisomerase (NCBI) | compare |
| b2499 | purM | -5.5 | -5.4 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b0907 | serC | -5.5 | -9.1 | phosphoserine aminotransferase (NCBI) | compare |
| b2020 | hisD | -5.4 | -10.1 | histidinol dehydrogenase (NCBI) | compare |
| b2763 | cysI | -5.4 | -9.1 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b2414 | cysK | -5.4 | -11.5 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b0243 | proA | -5.3 | -10.9 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0072 | leuC | -5.3 | -14.2 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b2557 | purL | -5.3 | -11.4 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b3960 | argH | -5.3 | -14.8 | argininosuccinate lyase (NCBI) | compare |
| b0074 | leuA | -5.2 | -12.1 | 2-isopropylmalate synthase (NCBI) | compare |
| b3771 | ilvD | -5.2 | -16.0 | dihydroxy-acid dehydratase (NCBI) | compare |
| b3389 | aroB | -5.2 | -12.1 | 3-dehydroquinate synthase (NCBI) | compare |
| b3770 | ilvE | -5.2 | -14.9 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b4232 | fbp | -5.2 | -13.4 | fructose-1,6-bisphosphatase (NCBI) | compare |
| b2913 | serA | -5.2 | -8.6 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b2752 | cysD | -5.1 | -6.2 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b2329 | aroC | -5.1 | -3.5 | chorismate synthase (NCBI) | compare |
| b3772 | ilvA | -5.1 | -16.1 | threonine dehydratase (NCBI) | compare |
| b3941 | metF | -5.1 | -12.0 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b4388 | serB | -5.0 | -7.7 | 3-phosphoserine phosphatase (NCBI) | compare |
| b2762 | cysH | -5.0 | -7.6 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b3172 | argG | -5.0 | -12.5 | argininosuccinate synthase (NCBI) | compare |
| b3008 | metC | -4.9 | -12.6 | cystathionine beta-lyase (NCBI) | compare |
| b3368 | cysG | -4.9 | -16.3 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b2019 | hisG | -4.9 | -7.1 | ATP phosphoribosyltransferase (NCBI) | compare |
| b4006 | purH | -4.9 | -14.5 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b0522 | purK | -4.9 | -10.9 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b2023 | hisH | -4.9 | -6.4 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b0908 | aroA | -4.8 | -7.4 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b1062 | pyrC | -4.8 | -9.2 | dihydroorotase (NCBI) | compare |
| b0071 | leuD | -4.7 | -9.6 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b2022 | hisB | -4.7 | -8.5 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b3281 | aroE | -4.7 | -18.8 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b2784 | relA | -4.7 | -10.5 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b2838 | lysA | -4.7 | -12.1 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b3959 | argB | -4.6 | -11.9 | acetylglutamate kinase (RefSeq) | compare |
| b0002 | thrA | -4.6 | -17.3 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b2422 | cysA | -4.6 | -9.9 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b2839 | lysR | -4.6 | -6.4 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2818 | argA | -4.6 | -10.7 | N-acetylglutamate synthase (NCBI) | compare |
| b2751 | cysN | -4.6 | -7.0 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b3957 | argE | -4.6 | -14.4 | acetylornithine deacetylase (NCBI) | compare |
| b0720 | gltA | -4.6 | -8.7 | citrate synthase (NCBI) | compare |
| b3773 | ilvY | -4.5 | -12.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3956 | ppc | -4.5 | -18.3 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b2764 | cysJ | -4.4 | -12.5 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b2024 | hisA | -4.4 | -2.3 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b2750 | cysC | -4.4 | -7.1 | adenylylsulfate kinase (NCBI) | compare |
| b2423 | cysW | -4.4 | -7.3 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b0523 | purE | -4.3 | -5.8 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b0386 | proC | -4.3 | -7.1 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b3958 | argC | -4.2 | -15.2 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b2026 | hisI | -4.1 | -8.8 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b3781 | trxA | -4.1 | -4.9 | thioredoxin 1 (VIMSS) | compare |
| b3642 | pyrE | -4.0 | -6.1 | orotate phosphoribosyltransferase (NCBI) | compare |
| b0242 | proB | -4.0 | -8.5 | gamma-glutamyl kinase (NCBI) | compare |
| b0003 | thrB | -4.0 | -7.5 | homoserine kinase (NCBI) | compare |
| b3839 | tatC | -3.9 | -12.8 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0945 | pyrD | -3.9 | -10.9 | dihydroorotate dehydrogenase (NCBI) | compare |
| b0033 | carB | -3.9 | -17.7 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b2600 | tyrA | -3.8 | -5.6 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b1232 | purU | -3.7 | -5.8 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b2025 | hisF | -3.6 | -5.4 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b3204 | ptsN | -3.6 | -5.4 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b1693 | aroD | -3.5 | -6.3 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b0145 | dksA | -3.5 | -3.4 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b0888 | trxB | -3.3 | -3.2 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b3939 | metB | -3.3 | -11.4 | cystathionine gamma-synthase (NCBI) | compare |
| b2479 | gcvR | -3.2 | -6.9 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b3926 | glpK | -3.1 | -15.5 | glycerol kinase (NCBI) | compare |
| b1292 | sapC | -3.1 | -3.0 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b2340 | sixA | -3.1 | -5.8 | phosphohistidine phosphatase (NCBI) | compare |
| b3390 | aroK | -3.0 | -2.9 | shikimate kinase I (NCBI) | compare |
| b0032 | carA | -3.0 | -6.2 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b4013 | metA | -2.9 | -7.7 | homoserine O-succinyltransferase (NCBI) | compare |
| b0722 | sdhD | -2.9 | -5.5 | succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) | compare |
| b0726 | sucA | -2.7 | -3.2 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b0737 | tolQ | -2.7 | -5.1 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b3870 | glnA | -2.7 | -1.8 | glutamine synthetase (NCBI) | compare |
| b0683 | fur | -2.6 | -2.5 | ferric uptake regulator (NCBI) | compare |
| b0113 | pdhR | -2.6 | -5.8 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b4245 | pyrB | -2.6 | -7.9 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b1262 | trpC | -2.6 | -4.2 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b2424 | cysU | -2.5 | -3.2 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b0142 | folK | -2.4 | -1.0 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b2501 | ppk | -2.4 | -9.2 | polyphosphate kinase (NCBI) | compare |
| b3849 | trkH | -2.4 | -12.4 | potassium transporter (NCBI) | compare |
| b2599 | pheA | -2.4 | -4.7 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b0724 | sdhB | -2.3 | -6.5 | succinate dehydrogenase, FeS subunit (NCBI) | compare |
| b2846 | yqeH | -2.2 | -1.5 | orf, hypothetical protein (VIMSS) | compare |
| b2286 | nuoC | -2.2 | -5.5 | NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) | compare |
| b2287 | nuoB | -2.2 | -4.6 | NADH dehydrogenase subunit B (NCBI) | compare |
| b1936 | intG | -2.1 | -1.5 | predicted defective phage integrase (pseudogene) (RefSeq) | compare |
| b0740 | tolB | -2.1 | -6.6 | translocation protein TolB precursor (NCBI) | compare |
| b4481 | rffT | -2.1 | -7.6 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b3671 | ilvB | -2.1 | -12.3 | acetolactate synthase large subunit (NCBI) | compare |
| b3650 | spoT | -2.1 | -8.1 | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | compare |
| b3792 | wzxE | -2.0 | -10.0 | O-antigen translocase (NCBI) | compare |
| b1293 | sapB | -2.0 | -1.6 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b4593 | ymgI | -2.0 | -1.9 | hypothetical protein (RefSeq) | compare |
| b3791 | rffA | -1.9 | -8.1 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b1291 | sapD | -1.9 | -2.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3927 | glpF | -1.9 | -8.1 | glycerol facilitator (NCBI) | compare |
| b2285 | nuoE | -1.9 | -3.0 | NADH dehydrogenase subunit E (NCBI) | compare |
| b0928 | aspC | -1.9 | -6.5 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b1865 | nudB | -1.9 | -1.4 | dATP pyrophosphohydrolase (NCBI) | compare |
| b0200 | gmhB | -1.9 | -1.3 | hypothetical protein (NCBI) | compare |
| b1536 | ydeI | -1.9 | -1.8 | hypothetical protein (NCBI) | compare |
| b3979 | thrT | -1.8 | -0.7 | tRNA-Thr (NCBI) | compare |
| b2531 | iscR | -1.8 | -2.4 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3236 | mdh | -1.8 | -5.3 | malate dehydrogenase (NCBI) | compare |
| b0481 | ybaK | -1.8 | -3.3 | hypothetical protein (NCBI) | compare |
| b0741 | pal | -1.7 | -3.7 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b0080 | fruR | -1.7 | -6.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b4246 | pyrL | -1.7 | -2.8 | pyrBI operon leader peptide (NCBI) | compare |
| b1129 | phoQ | -1.7 | -1.2 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b3212 | gltB | -1.7 | -12.2 | glutamate synthase, large subunit (NCBI) | compare |
| b3213 | gltD | -1.7 | -7.0 | glutamate synthase, 4Fe-4S protein, small subunit (NCBI) | compare |
| b0738 | tolR | -1.7 | -3.9 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b1563 | relE | -1.7 | -2.5 | Qin prophage; toxin of the RelE-RelB toxin-antitoxin system (NCBI) | compare |
| b0049 | apaH | -1.6 | -3.4 | diadenosinetetraphosphatase (NCBI) | compare |
| b1285 | gmr | -1.6 | -6.4 | modulator of Rnase II stability (NCBI) | compare |
| b2284 | nuoF | -1.6 | -4.6 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b0721 | sdhC | -1.6 | -4.4 | succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) | compare |
| b3426 | glpD | -1.6 | -1.1 | sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) | compare |
| b2363 | yfdT | -1.6 | -2.4 | CPS-53 (KpLE1) prophage; predicted protein (NCBI) | compare |
| b4128 | yjdK | -1.6 | -1.1 | hypothetical protein (NCBI) | compare |
| b2912 | ygfA | -1.6 | -4.4 | putative ligase (VIMSS) | compare |
| b4503 | yafF | -1.5 | -0.9 | no description | compare |
| b1235 | rssB | -1.5 | -6.4 | response regulator of RpoS (NCBI) | compare |
| b2279 | nuoK | -1.5 | -1.6 | NADH dehydrogenase subunit K (NCBI) | compare |
| b0723 | sdhA | -1.5 | -7.2 | succinate dehydrogenase flavoprotein subunit (NCBI) | compare |
| b0564 | appY | -1.5 | -0.8 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b2168 | fruK | -1.5 | -1.8 | 1-phosphofructokinase (NCBI) | compare |
| b3728 | pstS | -1.5 | -1.7 | phosphate transporter subunit (NCBI) | compare |
| b0739 | tolA | -1.4 | -3.5 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b0437 | clpP | -1.4 | -4.2 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b4191 | ulaR | -1.4 | -4.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3779 | gpp | -1.4 | -8.1 | guanosine pentaphosphatase/exopolyphosphatase (NCBI) | compare |
| b3456 | livM | -1.4 | -7.3 | leucine/isoleucine/valine transporter subunit (NCBI) | compare |
| b0730 | mngR | -1.4 | -1.8 | DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) | compare |
| b1346 | ydaQ | -1.4 | -2.0 | orf, hypothetical protein (VIMSS) | compare |
| b0075 | leuL | -1.3 | -3.1 | leu operon leader peptide (NCBI) | compare |
| b2217 | rcsB | -1.3 | -5.7 | DNA-binding response regulator in two-component regulatory system with RcsC and YojN (NCBI) | compare |
| b1709 | btuD | -1.3 | -1.3 | vitamin B12-transporter ATPase (NCBI) | compare |
| b3778 | rep | -1.3 | -6.4 | DNA helicase and single-stranded DNA-dependent ATPase (NCBI) | compare |
| b1182 | hlyE | -1.3 | -0.8 | hemolysin E (VIMSS) | compare |
| b0990 | cspG | -1.2 | -0.8 | DNA-binding transcriptional regulator (NCBI) | compare |
| b4533 | ynfO | -1.2 | -1.8 | Qin prophage; predicted protein (NCBI) | compare |
| b3237 | argR | -1.2 | -3.1 | arginine repressor (NCBI) | compare |
| b2603 | yfiR | -1.2 | -5.7 | hypothetical protein (NCBI) | compare |
| b3790 | rffC | -1.2 | -4.1 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b1758 | b1758 | -1.2 | -1.2 | putative cytochrome oxidase (VIMSS) | compare |
| b3457 | livH | -1.2 | -5.2 | leucine/isoleucine/valine transporter subunit (NCBI) | compare |
| b3611 | yibN | -1.2 | -3.0 | predicted rhodanese-related sulfurtransferase (NCBI) | compare |
| b3860 | dsbA | -1.2 | -6.4 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b1188 | ycgB | -1.2 | -4.4 | ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b2236 | yfaE | -1.2 | -1.8 | predicted 2Fe-2S cluster-containing protein (NCBI) | compare |
| b1877 | yecT | -1.2 | -1.8 | orf, hypothetical protein (VIMSS) | compare |
| b1575 | dicB | -1.2 | -1.8 | Qin prophage; cell division inhibition protein (NCBI) | compare |
| b1730 | ydjO | -1.2 | -1.3 | predicted protein (RefSeq) | compare |
| b2283 | nuoG | -1.1 | -5.3 | NADH:ubiquinone oxidoreductase, chain G (RefSeq) | compare |
| b3993 | thiE | -1.1 | -5.8 | thiamine-phosphate pyrophosphorylase (NCBI) | compare |
| b3290 | trkA | -1.1 | -1.3 | potassium transporter peripheral membrane component (NCBI) | compare |
| b0438 | clpX | -1.1 | -3.9 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b4146 | yjeK | -1.1 | -2.2 | predicted lysine aminomutase (NCBI) | compare |
| b4642 | yoeD | -1.1 | -1.6 | no description | compare |
| b2276 | nuoN | -1.1 | -4.4 | NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) | compare |
| b0767 | ybhE | -1.1 | -3.3 | 6-phosphogluconolactonase (NCBI) | compare |
| b4214 | cysQ | -1.1 | -6.2 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b3163 | nlpI | -1.1 | -3.6 | hypothetical protein (NCBI) | compare |
| b0889 | lrp | -1.1 | -2.4 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b1863 | ruvC | -1.1 | -2.0 | Holliday junction resolvase (NCBI) | compare |
| b0706 | ybfD | -1.1 | -1.7 | hypothetical protein (NCBI) | compare |
| b0167 | glnD | -1.1 | -2.1 | PII uridylyl-transferase (NCBI) | compare |
| b2163 | yeiL | -1.1 | -4.2 | putative transcriptional regulator (VIMSS) | compare |
| b3977 | tyrU | -1.0 | -0.7 | tRNA-Tyr (NCBI) | compare |
| b2093 | gatB | -1.0 | -3.1 | galactitol-specific enzyme IIB component of PTS (NCBI) | compare |
| b4640 | yoeG | -1.0 | -2.4 | no description | compare |
| b3838 | tatB | -1.0 | -3.7 | sec-independent translocase (NCBI) | compare |
| b2282 | nuoH | -1.0 | -2.8 | NADH dehydrogenase subunit H (NCBI) | compare |
| b0078 | ilvH | -1.0 | -5.8 | acetolactate synthase small subunit (NCBI) | compare |
| b4179 | vacB | -1.0 | -4.3 | putative enzyme (VIMSS) | compare |
| b2518 | ndk | -1.0 | -2.0 | nucleoside diphosphate kinase (NCBI) | compare |
| b4431 | rprA | -1.0 | -1.2 | Positive regulatory sRNA for RpoS translation; non-essential gene (RefSeq) | compare |
| b1231 | tyrT | -1.0 | -0.8 | tRNA-Tyr (NCBI) | compare |
| b2280 | nuoJ | -1.0 | -2.9 | NADH dehydrogenase subunit J (NCBI) | compare |
| b1773 | ydjI | -1.0 | -1.2 | predicted aldolase (NCBI) | compare |
| b4553 | ysaB | -1.0 | -5.2 | hypothetical protein (NCBI) | compare |