| | gene | name | fitness | t score | description | |
|---|
| b1192 | ldcA | -8.6 | -11.8 | L,D-carboxypeptidase A (NCBI) | compare |
| b2023 | hisH | -5.1 | -7.0 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b2025 | hisF | -4.9 | -4.7 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b2021 | hisC | -4.9 | -6.7 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b2499 | purM | -4.8 | -6.5 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b3839 | tatC | -4.7 | -14.3 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0386 | proC | -4.5 | -6.9 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2476 | purC | -4.1 | -4.9 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b2022 | hisB | -4.1 | -8.7 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2838 | lysA | -4.1 | -12.1 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b0243 | proA | -4.1 | -11.4 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0523 | purE | -4.1 | -5.5 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b3770 | ilvE | -4.1 | -14.5 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b3281 | aroE | -4.0 | -17.9 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b3389 | aroB | -4.0 | -13.3 | 3-dehydroquinate synthase (NCBI) | compare |
| b0908 | aroA | -3.9 | -10.0 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b3771 | ilvD | -3.9 | -15.3 | dihydroxy-acid dehydratase (NCBI) | compare |
| b0907 | serC | -3.7 | -9.3 | phosphoserine aminotransferase (NCBI) | compare |
| b2329 | aroC | -3.7 | -6.6 | chorismate synthase (NCBI) | compare |
| b3390 | aroK | -3.7 | -2.5 | shikimate kinase I (NCBI) | compare |
| b1260 | trpA | -3.7 | -4.3 | tryptophan synthase subunit alpha (NCBI) | compare |
| b0072 | leuC | -3.7 | -12.4 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b2557 | purL | -3.6 | -12.7 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b3959 | argB | -3.6 | -13.0 | acetylglutamate kinase (RefSeq) | compare |
| b4006 | purH | -3.6 | -14.3 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b4005 | purD | -3.5 | -11.4 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b3774 | ilvC | -3.5 | -16.5 | ketol-acid reductoisomerase (NCBI) | compare |
| b0074 | leuA | -3.5 | -9.7 | 2-isopropylmalate synthase (NCBI) | compare |
| b0004 | thrC | -3.5 | -8.4 | threonine synthase (NCBI) | compare |
| b0242 | proB | -3.5 | -7.2 | gamma-glutamyl kinase (NCBI) | compare |
| b0522 | purK | -3.5 | -10.8 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b1062 | pyrC | -3.5 | -9.2 | dihydroorotase (NCBI) | compare |
| b3772 | ilvA | -3.5 | -12.8 | threonine dehydratase (NCBI) | compare |
| b0740 | tolB | -3.5 | -6.6 | translocation protein TolB precursor (NCBI) | compare |
| b2019 | hisG | -3.4 | -5.9 | ATP phosphoribosyltransferase (NCBI) | compare |
| b2020 | hisD | -3.4 | -9.9 | histidinol dehydrogenase (NCBI) | compare |
| b0071 | leuD | -3.4 | -8.6 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b1861 | ruvA | -3.4 | -2.3 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b0002 | thrA | -3.4 | -16.0 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b4232 | fbp | -3.4 | -10.4 | fructose-1,6-bisphosphatase (NCBI) | compare |
| b3956 | ppc | -3.4 | -17.9 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b4388 | serB | -3.4 | -7.8 | 3-phosphoserine phosphatase (NCBI) | compare |
| b3941 | metF | -3.4 | -10.3 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b3172 | argG | -3.3 | -10.6 | argininosuccinate synthase (NCBI) | compare |
| b0053 | surA | -3.3 | -6.3 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b0073 | leuB | -3.3 | -8.0 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b2312 | purF | -3.3 | -7.6 | amidophosphoribosyltransferase (NCBI) | compare |
| b2479 | gcvR | -3.3 | -6.6 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b2762 | cysH | -3.3 | -8.0 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b0945 | pyrD | -3.2 | -10.6 | dihydroorotate dehydrogenase (NCBI) | compare |
| b3957 | argE | -3.2 | -12.9 | acetylornithine deacetylase (NCBI) | compare |
| b1693 | aroD | -3.1 | -7.3 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b1261 | trpB | -3.1 | -3.6 | tryptophan synthase subunit beta (NCBI) | compare |
| b0720 | gltA | -3.1 | -7.0 | citrate synthase (NCBI) | compare |
| b3792 | wzxE | -3.1 | -10.5 | O-antigen translocase (NCBI) | compare |
| b4013 | metA | -3.1 | -7.9 | homoserine O-succinyltransferase (NCBI) | compare |
| b3008 | metC | -3.1 | -10.3 | cystathionine beta-lyase (NCBI) | compare |
| b0726 | sucA | -3.0 | -3.6 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b1281 | pyrF | -3.0 | -4.6 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b0003 | thrB | -3.0 | -6.5 | homoserine kinase (NCBI) | compare |
| b2330 | yfcB | -3.0 | -2.0 | putative adenine-specific methylase (VIMSS) | compare |
| b0741 | pal | -2.9 | -5.2 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b3642 | pyrE | -2.9 | -4.9 | orotate phosphoribosyltransferase (NCBI) | compare |
| b2913 | serA | -2.9 | -9.7 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b3939 | metB | -2.9 | -9.3 | cystathionine gamma-synthase (NCBI) | compare |
| b2600 | tyrA | -2.8 | -5.7 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b0739 | tolA | -2.8 | -4.7 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b2818 | argA | -2.8 | -7.9 | N-acetylglutamate synthase (NCBI) | compare |
| b3960 | argH | -2.8 | -11.2 | argininosuccinate lyase (NCBI) | compare |
| b4245 | pyrB | -2.7 | -9.0 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b1830 | prc | -2.7 | -7.8 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b3958 | argC | -2.7 | -11.4 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b2763 | cysI | -2.6 | -9.5 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b3773 | ilvY | -2.6 | -7.8 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0145 | dksA | -2.6 | -3.8 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b2839 | lysR | -2.6 | -4.3 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b1860 | ruvB | -2.6 | -1.7 | Holliday junction DNA helicase B (NCBI) | compare |
| b2784 | relA | -2.6 | -9.9 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b4481 | rffT | -2.5 | -8.1 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b2830 | nudH | -2.5 | -2.8 | dinucleoside polyphosphate hydrolase (NCBI) | compare |
| b3926 | glpK | -2.5 | -14.2 | glycerol kinase (NCBI) | compare |
| b2024 | hisA | -2.5 | -2.2 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b3368 | cysG | -2.5 | -13.4 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b0033 | carB | -2.5 | -12.0 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b0142 | folK | -2.4 | -1.2 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b0737 | tolQ | -2.4 | -3.8 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0738 | tolR | -2.3 | -4.2 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b1536 | ydeI | -2.3 | -1.6 | hypothetical protein (NCBI) | compare |
| b0032 | carA | -2.3 | -5.2 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b3613 | yibP | -2.3 | -4.9 | putative membrane protein (VIMSS) | compare |
| b3838 | tatB | -2.3 | -6.2 | sec-independent translocase (NCBI) | compare |
| b2414 | cysK | -2.3 | -8.2 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b3791 | rffA | -2.2 | -8.1 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b2764 | cysJ | -2.2 | -10.1 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b2752 | cysD | -2.2 | -5.4 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b0890 | ftsK | -2.2 | -4.7 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b1290 | sapF | -2.2 | -2.1 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b2750 | cysC | -2.1 | -4.4 | adenylylsulfate kinase (NCBI) | compare |
| b3794 | rffM | -2.1 | -7.6 | putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) | compare |
| b3021 | ygiT | -2.0 | -2.6 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3790 | rffC | -2.0 | -5.5 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b4146 | yjeK | -1.9 | -2.6 | predicted lysine aminomutase (NCBI) | compare |
| b4042 | dgkA | -1.9 | -2.3 | diacylglycerol kinase (NCBI) | compare |
| b0439 | lon | -1.9 | -5.4 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b2599 | pheA | -1.9 | -4.9 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b3082 | ygjM | -1.9 | -1.3 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1217 | chaB | -1.8 | -1.9 | cation transport regulator (NCBI) | compare |
| b3163 | nlpI | -1.8 | -5.4 | hypothetical protein (NCBI) | compare |
| b1730 | ydjO | -1.8 | -1.7 | predicted protein (RefSeq) | compare |
| b2287 | nuoB | -1.8 | -4.1 | NADH dehydrogenase subunit B (NCBI) | compare |
| b4520 | ymgF | -1.8 | -2.4 | hypothetical protein (NCBI) | compare |
| b4128 | yjdK | -1.8 | -1.2 | hypothetical protein (NCBI) | compare |
| b2912 | ygfA | -1.7 | -3.9 | putative ligase (VIMSS) | compare |
| b1129 | phoQ | -1.7 | -1.7 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b3426 | glpD | -1.7 | -1.2 | sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) | compare |
| b1575 | dicB | -1.7 | -1.5 | Qin prophage; cell division inhibition protein (NCBI) | compare |
| b1292 | sapC | -1.7 | -2.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b4509 | ylcG | -1.7 | -2.8 | DLP12 prophage; predicted protein (NCBI) | compare |
| b3927 | glpF | -1.7 | -8.6 | glycerol facilitator (NCBI) | compare |
| b2026 | hisI | -1.7 | -6.9 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b2751 | cysN | -1.7 | -5.4 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b4202 | rpsR | -1.6 | -1.9 | 30S ribosomal protein S18 (NCBI) | compare |
| b3811 | xerC | -1.6 | -1.6 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b0683 | fur | -1.6 | -1.9 | ferric uptake regulator (NCBI) | compare |
| b1262 | trpC | -1.6 | -3.0 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b1182 | hlyE | -1.6 | -1.1 | hemolysin E (VIMSS) | compare |
| b1347 | ydaC | -1.6 | -1.0 | Rac prophage; predicted protein (NCBI) | compare |
| b0080 | fruR | -1.6 | -4.8 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0658 | ybeX | -1.5 | -1.8 | predicteed ion transport (NCBI) | compare |
| b3671 | ilvB | -1.5 | -8.4 | acetolactate synthase large subunit (NCBI) | compare |
| b3728 | pstS | -1.5 | -1.8 | phosphate transporter subunit (NCBI) | compare |
| b3786 | rffE | -1.5 | -9.6 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b4191 | ulaR | -1.5 | -3.8 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b4172 | hfq | -1.5 | -1.0 | RNA-binding protein Hfq (NCBI) | compare |
| b0075 | leuL | -1.5 | -4.2 | leu operon leader peptide (NCBI) | compare |
| b2282 | nuoH | -1.5 | -3.4 | NADH dehydrogenase subunit H (NCBI) | compare |
| b4436 | ryeC | -1.5 | -2.1 | Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) | compare |
| b0200 | gmhB | -1.5 | -1.4 | hypothetical protein (NCBI) | compare |
| b3870 | glnA | -1.5 | -2.6 | glutamine synthetase (NCBI) | compare |
| b0014 | dnaK | -1.5 | -1.9 | molecular chaperone DnaK (NCBI) | compare |
| b0880 | cspD | -1.5 | -2.3 | cold shock protein homolog (NCBI) | compare |
| b1103 | ycfF | -1.4 | -1.9 | orf, hypothetical protein (VIMSS) | compare |
| b1429 | tehA | -1.4 | -1.1 | potassium-tellurite ethidium and proflavin transporter (NCBI) | compare |
| b3205 | yhbJ | -1.4 | -3.8 | hypothetical protein (NCBI) | compare |
| b1762 | b1762 | -1.4 | -2.3 | orf, hypothetical protein (VIMSS) | compare |
| b3405 | ompR | -1.4 | -4.2 | osmolarity response regulator (NCBI) | compare |
| b3169 | nusA | -1.4 | -2.9 | transcription elongation factor NusA (NCBI) | compare |
| b3035 | tolC | -1.4 | -6.0 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) | compare |
| b2285 | nuoE | -1.3 | -2.2 | NADH dehydrogenase subunit E (NCBI) | compare |
| b1058 | yceO | -1.3 | -0.8 | hypothetical protein (NCBI) | compare |
| b1863 | ruvC | -1.3 | -2.3 | Holliday junction resolvase (NCBI) | compare |
| b3500 | gor | -1.3 | -1.7 | glutathione reductase (NCBI) | compare |
| b1252 | tonB | -1.3 | -2.7 | membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) | compare |
| b2518 | ndk | -1.3 | -2.1 | nucleoside diphosphate kinase (NCBI) | compare |
| b1130 | phoP | -1.3 | -0.9 | DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) | compare |
| b3784 | rfe | -1.3 | -8.7 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b0957 | ompA | -1.3 | -2.5 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b4701 | sokX | -1.3 | -1.1 | sok-related sRNA, function unknown (RefSeq) | compare |
| b3781 | trxA | -1.3 | -3.1 | thioredoxin 1 (VIMSS) | compare |
| b3650 | spoT | -1.2 | -4.8 | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | compare |
| b3849 | trkH | -1.2 | -7.6 | potassium transporter (NCBI) | compare |
| b0888 | trxB | -1.2 | -2.7 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b1506 | yneL | -1.2 | -1.1 | predicted transcriptional regulator (NCBI) | compare |
| b2340 | sixA | -1.2 | -3.1 | phosphohistidine phosphatase (NCBI) | compare |
| b2278 | nuoL | -1.2 | -6.3 | NADH dehydrogenase subunit L (NCBI) | compare |
| b1232 | purU | -1.2 | -3.6 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b2501 | ppk | -1.2 | -6.3 | polyphosphate kinase (NCBI) | compare |
| b1551 | b1551 | -1.2 | -0.8 | orf, hypothetical protein (VIMSS) | compare |
| b1357 | ydaS | -1.2 | -1.5 | Rac prophage; predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2567 | rnc | -1.2 | -0.8 | ribonuclease III (NCBI) | compare |
| b0437 | clpP | -1.2 | -4.2 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b3935 | priA | -1.2 | -1.9 | primosome assembly protein PriA (NCBI) | compare |
| b1263 | trpD | -1.2 | -2.0 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b3787 | rffD | -1.2 | -6.5 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b4242 | mgtA | -1.2 | -6.5 | magnesium transporter (NCBI) | compare |
| b3053 | glnE | -1.1 | -6.4 | fused deadenylyltransferase/adenylyltransferase for glutamine synthetase (NCBI) | compare |
| b0630 | lipB | -1.1 | -0.8 | protein of lipoate biosynthesis (VIMSS) | compare |
| b4676 | yoaK | -1.1 | -0.7 | expressed protein (RefSeq) | compare |
| b4552 | yrhC | -1.1 | -0.7 | no description | compare |
| b4603 | rseX | -1.1 | -1.1 | sRNA regulating ompA and ompC translation, with Hfq (RefSeq) | compare |
| b2017 | yefM | -1.1 | -1.2 | orf, hypothetical protein (VIMSS) | compare |
| b3463 | ftsE | -1.1 | -0.7 | predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) | compare |
| b3778 | rep | -1.1 | -5.9 | DNA helicase and single-stranded DNA-dependent ATPase (NCBI) | compare |
| b3443 | yrhA | -1.1 | -1.2 | orf, hypothetical protein (VIMSS) | compare |
| b0722 | sdhD | -1.1 | -2.8 | succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) | compare |
| b3052 | rfaE | -1.1 | -3.7 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b1527 | yneK | -1.1 | -1.8 | hypothetical protein (NCBI) | compare |
| b2369 | evgA | -1.1 | -2.6 | DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) | compare |
| b2055 | wcaE | -1.0 | -0.7 | predicted glycosyl transferase (NCBI) | compare |
| b1259 | yciG | -1.0 | -1.7 | orf, hypothetical protein (VIMSS) | compare |
| b1518 | lsrG | -1.0 | -1.8 | autoinducer-2 (AI-2) modifying protein LsrG (NCBI) | compare |
| b2286 | nuoC | -1.0 | -3.5 | NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) | compare |
| b2689 | yqaA | -1.0 | -2.8 | conserved inner membrane protein (NCBI) | compare |
| b3672 | ivbL | -1.0 | -1.9 | ilvB operon leader peptide (NCBI) | compare |
| b1185 | dsbB | -1.0 | -2.5 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b3204 | ptsN | -1.0 | -3.1 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b1848 | yebG | -1.0 | -1.4 | conserved protein regulated by LexA (NCBI) | compare |
| b1287 | yciW | -1.0 | -3.3 | putative oxidoreductase (VIMSS) | compare |
| b1165 | ymgA | -1.0 | -0.7 | hypothetical protein (NCBI) | compare |
| b3889 | yiiE | -1.0 | -2.0 | predicted transcriptional regulator (RefSeq) | compare |