| | gene | name | fitness | t score | description | |
|---|
| b1192 | ldcA | -8.1 | -11.2 | L,D-carboxypeptidase A (NCBI) | compare |
| b3839 | tatC | -4.7 | -14.9 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0242 | proB | -4.4 | -8.3 | gamma-glutamyl kinase (NCBI) | compare |
| b2021 | hisC | -4.3 | -8.0 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b0386 | proC | -4.2 | -9.5 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2913 | serA | -4.2 | -11.9 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b1260 | trpA | -4.1 | -7.2 | tryptophan synthase subunit alpha (NCBI) | compare |
| b0726 | sucA | -4.1 | -5.5 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b2025 | hisF | -4.0 | -6.2 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b3770 | ilvE | -4.0 | -16.0 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b2557 | purL | -4.0 | -13.6 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b4388 | serB | -3.9 | -7.8 | 3-phosphoserine phosphatase (NCBI) | compare |
| b3960 | argH | -3.9 | -17.8 | argininosuccinate lyase (NCBI) | compare |
| b0737 | tolQ | -3.9 | -5.2 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0243 | proA | -3.8 | -13.9 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b3771 | ilvD | -3.8 | -17.0 | dihydroxy-acid dehydratase (NCBI) | compare |
| b2329 | aroC | -3.8 | -9.8 | chorismate synthase (NCBI) | compare |
| b0073 | leuB | -3.8 | -12.0 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b0071 | leuD | -3.8 | -8.7 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b1261 | trpB | -3.8 | -3.6 | tryptophan synthase subunit beta (NCBI) | compare |
| b4232 | fbp | -3.7 | -14.2 | fructose-1,6-bisphosphatase (NCBI) | compare |
| b0908 | aroA | -3.7 | -14.7 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b2499 | purM | -3.7 | -9.6 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b2838 | lysA | -3.7 | -12.4 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b4005 | purD | -3.7 | -11.0 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b0072 | leuC | -3.7 | -12.5 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b0739 | tolA | -3.7 | -5.6 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b3281 | aroE | -3.7 | -18.1 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b2020 | hisD | -3.7 | -11.9 | histidinol dehydrogenase (NCBI) | compare |
| b0003 | thrB | -3.6 | -8.0 | homoserine kinase (NCBI) | compare |
| b3939 | metB | -3.6 | -15.1 | cystathionine gamma-synthase (NCBI) | compare |
| b3941 | metF | -3.6 | -13.5 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b0522 | purK | -3.6 | -11.7 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b1062 | pyrC | -3.6 | -10.9 | dihydroorotase (NCBI) | compare |
| b3956 | ppc | -3.5 | -20.8 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b3772 | ilvA | -3.5 | -16.6 | threonine dehydratase (NCBI) | compare |
| b3172 | argG | -3.5 | -14.2 | argininosuccinate synthase (NCBI) | compare |
| b4006 | purH | -3.5 | -14.6 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b3774 | ilvC | -3.5 | -16.0 | ketol-acid reductoisomerase (NCBI) | compare |
| b0738 | tolR | -3.5 | -5.3 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b2312 | purF | -3.5 | -7.5 | amidophosphoribosyltransferase (NCBI) | compare |
| b2024 | hisA | -3.5 | -4.1 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b3389 | aroB | -3.5 | -15.6 | 3-dehydroquinate synthase (NCBI) | compare |
| b2784 | relA | -3.4 | -12.8 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b0523 | purE | -3.4 | -3.8 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b0074 | leuA | -3.4 | -11.9 | 2-isopropylmalate synthase (NCBI) | compare |
| b1693 | aroD | -3.4 | -11.3 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b0004 | thrC | -3.4 | -10.2 | threonine synthase (NCBI) | compare |
| b3642 | pyrE | -3.4 | -6.1 | orotate phosphoribosyltransferase (NCBI) | compare |
| b0002 | thrA | -3.3 | -16.4 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b0740 | tolB | -3.3 | -9.1 | translocation protein TolB precursor (NCBI) | compare |
| b4013 | metA | -3.2 | -7.9 | homoserine O-succinyltransferase (NCBI) | compare |
| b2022 | hisB | -3.2 | -10.1 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2023 | hisH | -3.2 | -7.1 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b0907 | serC | -3.2 | -9.5 | phosphoserine aminotransferase (NCBI) | compare |
| b2764 | cysJ | -3.1 | -12.4 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b0033 | carB | -3.1 | -17.7 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b0145 | dksA | -3.1 | -4.2 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b2414 | cysK | -3.1 | -12.9 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b2476 | purC | -3.1 | -4.0 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b3926 | glpK | -3.1 | -17.4 | glycerol kinase (NCBI) | compare |
| b4245 | pyrB | -3.1 | -14.0 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b0945 | pyrD | -3.0 | -14.4 | dihydroorotate dehydrogenase (NCBI) | compare |
| b2762 | cysH | -3.0 | -10.5 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b3957 | argE | -2.9 | -16.2 | acetylornithine deacetylase (NCBI) | compare |
| b0564 | appY | -2.9 | -1.5 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b2763 | cysI | -2.9 | -13.1 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b2600 | tyrA | -2.9 | -7.2 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b3008 | metC | -2.9 | -11.4 | cystathionine beta-lyase (NCBI) | compare |
| b2751 | cysN | -2.8 | -9.2 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b2752 | cysD | -2.8 | -9.8 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b2019 | hisG | -2.8 | -5.3 | ATP phosphoribosyltransferase (NCBI) | compare |
| b3773 | ilvY | -2.8 | -13.1 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0720 | gltA | -2.8 | -8.5 | citrate synthase (NCBI) | compare |
| b2479 | gcvR | -2.7 | -8.3 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b0888 | trxB | -2.7 | -6.9 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b3958 | argC | -2.7 | -16.1 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b0200 | gmhB | -2.7 | -3.6 | hypothetical protein (NCBI) | compare |
| b3426 | glpD | -2.7 | -4.4 | sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) | compare |
| b0032 | carA | -2.7 | -11.1 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b2818 | argA | -2.6 | -9.8 | N-acetylglutamate synthase (NCBI) | compare |
| b3959 | argB | -2.6 | -12.0 | acetylglutamate kinase (RefSeq) | compare |
| b2750 | cysC | -2.6 | -8.0 | adenylylsulfate kinase (NCBI) | compare |
| b3368 | cysG | -2.6 | -16.1 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b2567 | rnc | -2.6 | -1.7 | ribonuclease III (NCBI) | compare |
| b1861 | ruvA | -2.5 | -2.4 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b2839 | lysR | -2.5 | -4.7 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2026 | hisI | -2.5 | -7.0 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b3870 | glnA | -2.4 | -4.3 | glutamine synthetase (NCBI) | compare |
| b1281 | pyrF | -2.4 | -2.9 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b3613 | yibP | -2.3 | -6.7 | putative membrane protein (VIMSS) | compare |
| b3082 | ygjM | -2.3 | -3.0 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3927 | glpF | -2.2 | -12.1 | glycerol facilitator (NCBI) | compare |
| b3781 | trxA | -2.1 | -7.1 | thioredoxin 1 (VIMSS) | compare |
| b1677 | lpp | -2.1 | -4.3 | murein lipoprotein (NCBI) | compare |
| b3792 | wzxE | -2.1 | -10.8 | O-antigen translocase (NCBI) | compare |
| b0741 | pal | -2.1 | -5.0 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b0114 | aceE | -2.0 | -1.9 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b3728 | pstS | -2.0 | -3.7 | phosphate transporter subunit (NCBI) | compare |
| b2287 | nuoB | -1.9 | -4.8 | NADH dehydrogenase subunit B (NCBI) | compare |
| b3791 | rffA | -1.9 | -7.5 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b3790 | rffC | -1.9 | -7.3 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b1290 | sapF | -1.8 | -3.0 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3838 | tatB | -1.8 | -5.2 | sec-independent translocase (NCBI) | compare |
| b2285 | nuoE | -1.7 | -2.5 | NADH dehydrogenase subunit E (NCBI) | compare |
| b1860 | ruvB | -1.7 | -2.2 | Holliday junction DNA helicase B (NCBI) | compare |
| b0439 | lon | -1.7 | -6.5 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b4481 | rffT | -1.7 | -6.3 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b1292 | sapC | -1.7 | -3.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1476 | fdnI | -1.7 | -1.7 | formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) | compare |
| b2313 | cvpA | -1.6 | -3.8 | membrane protein required for colicin V production (NCBI) | compare |
| b3204 | ptsN | -1.6 | -5.5 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b1263 | trpD | -1.6 | -2.6 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b2599 | pheA | -1.6 | -4.4 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b1293 | sapB | -1.6 | -2.1 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3671 | ilvB | -1.6 | -12.2 | acetolactate synthase large subunit (NCBI) | compare |
| b0080 | fruR | -1.6 | -7.3 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b1262 | trpC | -1.6 | -2.9 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b4146 | yjeK | -1.5 | -3.3 | predicted lysine aminomutase (NCBI) | compare |
| b1264 | trpE | -1.5 | -4.0 | anthranilate synthase component I (NCBI) | compare |
| b2504 | yfgG | -1.5 | -1.4 | Negative regulator of nickel and cobalt uptake (YfgG) (from data) | compare |
| b1830 | prc | -1.4 | -7.1 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b1160 | elbA | -1.4 | -1.6 | hypothetical protein (NCBI) | compare |
| b1129 | phoQ | -1.4 | -1.4 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b2642 | yfjW | -1.4 | -1.6 | CP4-57 prophage; predicted inner membrane protein (NCBI) | compare |
| b4048 | yjbM | -1.4 | -1.6 | hypothetical protein (NCBI) | compare |
| b3443 | yrhA | -1.4 | -2.4 | orf, hypothetical protein (VIMSS) | compare |
| b1231 | tyrT | -1.4 | -1.4 | tRNA-Tyr (NCBI) | compare |
| b2912 | ygfA | -1.4 | -4.9 | putative ligase (VIMSS) | compare |
| b1361 | ydaW | -1.4 | -0.8 | orf, hypothetical protein (VIMSS) | compare |
| b4593 | ymgI | -1.4 | -1.3 | hypothetical protein (RefSeq) | compare |
| b0890 | ftsK | -1.4 | -5.5 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b0075 | leuL | -1.3 | -3.7 | leu operon leader peptide (NCBI) | compare |
| b3053 | glnE | -1.3 | -8.4 | fused deadenylyltransferase/adenylyltransferase for glutamine synthetase (NCBI) | compare |
| b2422 | cysA | -1.3 | -7.9 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b4242 | mgtA | -1.3 | -8.5 | magnesium transporter (NCBI) | compare |
| b2501 | ppk | -1.3 | -8.0 | polyphosphate kinase (NCBI) | compare |
| b3672 | ivbL | -1.3 | -3.4 | ilvB operon leader peptide (NCBI) | compare |
| b3849 | trkH | -1.3 | -8.9 | potassium transporter (NCBI) | compare |
| b2424 | cysU | -1.3 | -2.7 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b2820 | recB | -1.3 | -1.5 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b0167 | glnD | -1.3 | -4.4 | PII uridylyl-transferase (NCBI) | compare |
| b3863 | polA | -1.3 | -1.7 | DNA polymerase I (NCBI) | compare |
| b4177 | purA | -1.3 | -0.9 | adenylosuccinate synthetase (NCBI) | compare |
| b0053 | surA | -1.2 | -4.9 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b3650 | spoT | -1.2 | -5.1 | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | compare |
| b4520 | ymgF | -1.2 | -2.0 | hypothetical protein (NCBI) | compare |
| b1363 | trkG | -1.2 | -1.4 | Rac prophage; potassium transporter subunit (NCBI) | compare |
| b3390 | aroK | -1.2 | -2.5 | shikimate kinase I (NCBI) | compare |
| b2531 | iscR | -1.2 | -2.5 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3794 | rffM | -1.2 | -6.5 | putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) | compare |
| b1850 | eda | -1.2 | -1.2 | keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) | compare |
| b3021 | ygiT | -1.2 | -2.1 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2318 | truA | -1.2 | -3.6 | tRNA pseudouridine synthase A (NCBI) | compare |
| b2278 | nuoL | -1.1 | -7.2 | NADH dehydrogenase subunit L (NCBI) | compare |
| b4214 | cysQ | -1.1 | -7.6 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b2340 | sixA | -1.1 | -3.6 | phosphohistidine phosphatase (NCBI) | compare |
| b4155 | yjeA | -1.1 | -0.7 | putative lysyl-tRNA synthetase (VIMSS) | compare |
| b0500 | ybbD | -1.1 | -0.7 | hypothetical protein (RefSeq) | compare |
| b4246 | pyrL | -1.1 | -1.6 | pyrBI operon leader peptide (NCBI) | compare |
| b2188 | yejM | -1.1 | -6.5 | predicted hydrolase, inner membrane (NCBI) | compare |
| b2934 | cmtB | -1.1 | -1.0 | predicted mannitol-specific enzyme IIA component of PTS (NCBI) | compare |
| b0928 | aspC | -1.0 | -4.9 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b3860 | dsbA | -1.0 | -7.5 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b2288 | nuoA | -1.0 | -2.3 | NADH dehydrogenase I chain A (VIMSS) | compare |
| b1130 | phoP | -1.0 | -1.5 | DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) | compare |
| b3163 | nlpI | -1.0 | -3.4 | hypothetical protein (NCBI) | compare |
| b3290 | trkA | -1.0 | -2.4 | potassium transporter peripheral membrane component (NCBI) | compare |
| b1232 | purU | -1.0 | -4.4 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b2277 | nuoM | -1.0 | -5.1 | NADH dehydrogenase subunit M (NCBI) | compare |
| b4045 | yjbJ | -1.0 | -1.9 | predicted stress response protein (NCBI) | compare |
| b0964 | yccT | -1.0 | -4.1 | hypothetical protein (NCBI) | compare |
| b3787 | rffD | -1.0 | -7.4 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b4590 | ybfK | -1.0 | -1.4 | hypothetical protein (RefSeq) | compare |
| b2286 | nuoC | -1.0 | -4.7 | NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) | compare |
| b2282 | nuoH | -1.0 | -3.6 | NADH dehydrogenase subunit H (NCBI) | compare |
| b4451 | ryhB | -1.0 | -1.0 | Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) | compare |
| b2259 | pmrD | -1.0 | -1.3 | polymyxin resistance protein B (VIMSS) | compare |
| b3500 | gor | -1.0 | -1.6 | glutathione reductase (NCBI) | compare |
| b2822 | recC | -1.0 | -4.0 | exonuclease V (RecBCD complex), gamma chain (NCBI) | compare |
| b3035 | tolC | -1.0 | -5.5 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) | compare |
| b1285 | gmr | -1.0 | -5.2 | modulator of Rnase II stability (NCBI) | compare |
| b3786 | rffE | -0.9 | -6.8 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b0113 | pdhR | -0.9 | -3.0 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b2284 | nuoF | -0.9 | -3.7 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b0550 | rusA | -0.9 | -3.2 | DLP12 prophage; endonuclease RUS (NCBI) | compare |
| b4480 | hdfR | -0.9 | -4.0 | transcriptional regulator HdfR (NCBI) | compare |
| b2423 | cysW | -0.9 | -3.9 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b4179 | vacB | -0.9 | -4.5 | putative enzyme (VIMSS) | compare |
| b2283 | nuoG | -0.9 | -4.5 | NADH:ubiquinone oxidoreductase, chain G (RefSeq) | compare |
| b3609 | secB | -0.9 | -2.1 | export protein SecB (NCBI) | compare |
| b1882 | cheY | -0.9 | -0.6 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b3169 | nusA | -0.9 | -2.0 | transcription elongation factor NusA (NCBI) | compare |
| b3212 | gltB | -0.9 | -7.4 | glutamate synthase, large subunit (NCBI) | compare |
| b1545 | pinQ | -0.9 | -0.3 | Qin prophage; predicted site-specific recombinase (NCBI) | compare |
| b3726 | pstA | -0.8 | -3.7 | phosphate transporter subunit (NCBI) | compare |
| b0721 | sdhC | -0.8 | -3.5 | succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) | compare |
| b3463 | ftsE | -0.8 | -1.4 | predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) | compare |
| b2276 | nuoN | -0.8 | -3.6 | NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) | compare |
| b1164 | ycgZ | -0.8 | -1.5 | hypothetical protein (NCBI) | compare |