| | gene | name | fitness | t score | description | |
|---|
| b1192 | ldcA | -5.3 | -8.9 | L,D-carboxypeptidase A (NCBI) | compare |
| b0014 | dnaK | -5.3 | -3.7 | molecular chaperone DnaK (NCBI) | compare |
| b3941 | metF | -4.0 | -13.0 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b1260 | trpA | -3.9 | -7.4 | tryptophan synthase subunit alpha (NCBI) | compare |
| b2750 | cysC | -3.8 | -7.6 | adenylylsulfate kinase (NCBI) | compare |
| b3831 | udp | -3.7 | -15.2 | uridine phosphorylase (NCBI) | conserved |
| b0523 | purE | -3.6 | -5.6 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b3774 | ilvC | -3.6 | -17.4 | ketol-acid reductoisomerase (NCBI) | compare |
| b2913 | serA | -3.6 | -12.9 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b0908 | aroA | -3.5 | -13.8 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b2021 | hisC | -3.5 | -6.3 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b2600 | tyrA | -3.5 | -11.1 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b4383 | deoB | -3.5 | -12.2 | phosphopentomutase (NCBI) | conserved |
| b0386 | proC | -3.5 | -9.0 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b0242 | proB | -3.4 | -10.3 | gamma-glutamyl kinase (NCBI) | compare |
| b0033 | carB | -3.4 | -18.5 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b3958 | argC | -3.4 | -15.6 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b3770 | ilvE | -3.4 | -17.2 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b1290 | sapF | -3.4 | -3.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3772 | ilvA | -3.3 | -14.5 | threonine dehydratase (NCBI) | compare |
| b2414 | cysK | -3.3 | -11.5 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b0072 | leuC | -3.3 | -14.2 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b3008 | metC | -3.3 | -13.0 | cystathionine beta-lyase (NCBI) | compare |
| b2025 | hisF | -3.3 | -8.1 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b2329 | aroC | -3.3 | -9.0 | chorismate synthase (NCBI) | compare |
| b2752 | cysD | -3.2 | -7.5 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b0243 | proA | -3.2 | -13.5 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b2763 | cysI | -3.2 | -12.3 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b4013 | metA | -3.2 | -6.2 | homoserine O-succinyltransferase (NCBI) | compare |
| b2024 | hisA | -3.2 | -4.3 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b3771 | ilvD | -3.2 | -15.0 | dihydroxy-acid dehydratase (NCBI) | compare |
| b2764 | cysJ | -3.2 | -12.5 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b3959 | argB | -3.2 | -15.0 | acetylglutamate kinase (RefSeq) | compare |
| b0002 | thrA | -3.2 | -17.1 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b2168 | fruK | -3.1 | -2.1 | 1-phosphofructokinase (NCBI) | compare |
| b0074 | leuA | -3.1 | -13.8 | 2-isopropylmalate synthase (NCBI) | compare |
| b3368 | cysG | -3.1 | -19.3 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b0720 | gltA | -3.1 | -11.1 | citrate synthase (NCBI) | compare |
| b2751 | cysN | -3.1 | -13.0 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b3172 | argG | -3.1 | -14.6 | argininosuccinate synthase (NCBI) | compare |
| b3957 | argE | -3.1 | -17.6 | acetylornithine deacetylase (NCBI) | compare |
| b0907 | serC | -3.1 | -8.8 | phosphoserine aminotransferase (NCBI) | compare |
| b3960 | argH | -3.1 | -14.0 | argininosuccinate lyase (NCBI) | compare |
| b1693 | aroD | -3.0 | -9.2 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b0032 | carA | -3.0 | -8.0 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b4006 | purH | -3.0 | -17.1 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b0073 | leuB | -3.0 | -13.0 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b2019 | hisG | -3.0 | -7.5 | ATP phosphoribosyltransferase (NCBI) | compare |
| b3281 | aroE | -3.0 | -17.4 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b3389 | aroB | -2.9 | -13.3 | 3-dehydroquinate synthase (NCBI) | compare |
| b0071 | leuD | -2.9 | -7.6 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b3939 | metB | -2.9 | -13.4 | cystathionine gamma-synthase (NCBI) | compare |
| b2476 | purC | -2.9 | -6.0 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b2022 | hisB | -2.9 | -10.1 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2818 | argA | -2.8 | -12.5 | N-acetylglutamate synthase (NCBI) | compare |
| b3839 | tatC | -2.8 | -13.2 | TatABCE protein translocation system subunit (NCBI) | compare |
| b4388 | serB | -2.7 | -9.1 | 3-phosphoserine phosphatase (NCBI) | compare |
| b2020 | hisD | -2.7 | -10.5 | histidinol dehydrogenase (NCBI) | compare |
| b2312 | purF | -2.7 | -9.4 | amidophosphoribosyltransferase (NCBI) | compare |
| b2023 | hisH | -2.6 | -5.4 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b0004 | thrC | -2.6 | -8.5 | threonine synthase (NCBI) | compare |
| b2557 | purL | -2.6 | -14.2 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b2784 | relA | -2.6 | -12.5 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b3870 | glnA | -2.6 | -3.5 | glutamine synthetase (NCBI) | compare |
| b0003 | thrB | -2.6 | -7.7 | homoserine kinase (NCBI) | compare |
| b0522 | purK | -2.5 | -8.8 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b4005 | purD | -2.5 | -13.1 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b3956 | ppc | -2.5 | -18.1 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b2499 | purM | -2.4 | -7.1 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b2762 | cysH | -2.4 | -8.6 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b1261 | trpB | -2.4 | -5.0 | tryptophan synthase subunit beta (NCBI) | compare |
| b2026 | hisI | -2.4 | -10.0 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b4018 | iclR | -2.3 | -10.8 | repressor of aceBA operon (VIMSS) | compare |
| b2838 | lysA | -2.3 | -12.7 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b3773 | ilvY | -2.3 | -10.4 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2846 | yqeH | -2.3 | -1.5 | orf, hypothetical protein (VIMSS) | compare |
| b4702 | mgtL | -2.3 | -2.7 | regulatory leader peptide for mgtA (NCBI) | compare |
| b3671 | ilvB | -2.3 | -14.4 | acetolactate synthase large subunit (NCBI) | compare |
| b1861 | ruvA | -2.3 | -2.1 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b0015 | dnaJ | -2.2 | -10.7 | chaperone Hsp40, co-chaperone with DnaK (NCBI) | compare |
| b3212 | gltB | -2.1 | -15.2 | glutamate synthase, large subunit (NCBI) | compare |
| b1262 | trpC | -2.1 | -4.3 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b1292 | sapC | -2.0 | -3.1 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1291 | sapD | -2.0 | -2.3 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b4503 | yafF | -2.0 | -1.2 | no description | compare |
| b4214 | cysQ | -2.0 | -10.8 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b2741 | rpoS | -2.0 | -7.2 | RNA polymerase sigma factor (NCBI) | compare |
| b0564 | appY | -2.0 | -1.7 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b3213 | gltD | -2.0 | -11.2 | glutamate synthase, 4Fe-4S protein, small subunit (NCBI) | compare |
| b1422 | ydcI | -1.9 | -6.9 | putative transcriptional regulator LYSR-type (VIMSS) | compare |
| b0113 | pdhR | -1.9 | -5.3 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b2839 | lysR | -1.9 | -6.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3205 | yhbJ | -1.8 | -6.0 | hypothetical protein (NCBI) | compare |
| b2599 | pheA | -1.8 | -5.5 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b0200 | gmhB | -1.8 | -2.7 | hypothetical protein (NCBI) | compare |
| b3672 | ivbL | -1.8 | -3.9 | ilvB operon leader peptide (NCBI) | compare |
| b0437 | clpP | -1.8 | -6.9 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b1783 | yeaG | -1.7 | -9.1 | yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b2934 | cmtB | -1.7 | -1.2 | predicted mannitol-specific enzyme IIA component of PTS (NCBI) | compare |
| b2894 | xerD | -1.7 | -1.6 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b3781 | trxA | -1.7 | -5.6 | thioredoxin 1 (VIMSS) | compare |
| b3469 | zntA | -1.7 | -8.7 | zinc, cobalt and lead efflux system (NCBI) | compare |
| b0167 | glnD | -1.7 | -4.3 | PII uridylyl-transferase (NCBI) | compare |
| b0438 | clpX | -1.7 | -7.8 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b2424 | cysU | -1.7 | -3.3 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b1235 | rssB | -1.6 | -8.7 | response regulator of RpoS (NCBI) | compare |
| b1836 | yebV | -1.6 | -5.6 | orf, hypothetical protein (VIMSS) | compare |
| b0767 | ybhE | -1.6 | -3.9 | 6-phosphogluconolactonase (NCBI) | compare |
| b2340 | sixA | -1.6 | -5.3 | phosphohistidine phosphatase (NCBI) | compare |
| b2479 | gcvR | -1.6 | -6.4 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b1188 | ycgB | -1.6 | -7.8 | ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b3021 | ygiT | -1.6 | -3.2 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2422 | cysA | -1.6 | -8.8 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b1161 | ycgX | -1.5 | -0.9 | hypothetical protein (NCBI) | compare |
| b0889 | lrp | -1.5 | -4.1 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b4395 | ytjC | -1.5 | -5.0 | phosphoglycerate mutase (NCBI) | compare |
| b2330 | yfcB | -1.5 | -2.2 | putative adenine-specific methylase (VIMSS) | compare |
| b3792 | wzxE | -1.5 | -8.3 | O-antigen translocase (NCBI) | compare |
| b0964 | yccT | -1.5 | -6.4 | hypothetical protein (NCBI) | compare |
| b3790 | rffC | -1.5 | -5.5 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b0953 | rmf | -1.5 | -3.0 | ribosome modulation factor (NCBI) | compare |
| b2423 | cysW | -1.5 | -5.2 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b0817 | mntR | -1.5 | -5.9 | DNA-binding transcriptional regulator of mntH (NCBI) | compare |
| b4172 | hfq | -1.5 | -1.0 | RNA-binding protein Hfq (NCBI) | compare |
| b0440 | hupB | -1.5 | -6.8 | HU, DNA-binding transcriptional regulator, beta subunit (NCBI) | compare |
| b0728 | sucC | -1.4 | -6.7 | succinyl-CoA synthetase subunit beta (NCBI) | compare |
| b0114 | aceE | -1.4 | -1.9 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b0726 | sucA | -1.4 | -4.5 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b0080 | fruR | -1.4 | -6.5 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3162 | deaD | -1.4 | -5.2 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b2287 | nuoB | -1.4 | -3.9 | NADH dehydrogenase subunit B (NCBI) | compare |
| b2964 | nupG | -1.4 | -9.3 | transport of nucleosides, permease protein (VIMSS) | compare |
| b3806 | cyaA | -1.4 | -6.2 | adenylate cyclase (NCBI) | compare |
| b2500 | purN | -1.4 | -7.1 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b2912 | ygfA | -1.4 | -4.0 | putative ligase (VIMSS) | compare |
| b4685 | yrbN | -1.3 | -3.2 | expressed protein (RefSeq) | compare |
| b1784 | yeaH | -1.3 | -5.3 | yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b3916 | pfkA | -1.3 | -3.4 | 6-phosphofructokinase (NCBI) | compare |
| b2282 | nuoH | -1.3 | -3.1 | NADH dehydrogenase subunit H (NCBI) | compare |
| b3204 | ptsN | -1.3 | -4.3 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b1286 | rnb | -1.3 | -2.8 | exoribonuclease II (NCBI) | compare |
| b3728 | pstS | -1.3 | -2.8 | phosphate transporter subunit (NCBI) | compare |
| b1429 | tehA | -1.3 | -1.6 | potassium-tellurite ethidium and proflavin transporter (NCBI) | compare |
| b0729 | sucD | -1.3 | -3.2 | succinyl-CoA synthetase subunit alpha (NCBI) | compare |
| b4701 | sokX | -1.2 | -1.2 | sok-related sRNA, function unknown (RefSeq) | compare |
| b2475 | ypfJ | -1.2 | -7.3 | hypothetical protein (NCBI) | compare |
| b0145 | dksA | -1.2 | -2.7 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b3791 | rffA | -1.2 | -6.4 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b4481 | rffT | -1.2 | -6.5 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b0888 | trxB | -1.2 | -4.2 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b0739 | tolA | -1.2 | -4.0 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b1594 | dgsA | -1.2 | -3.9 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3601 | mtlR | -1.2 | -6.5 | DNA-binding repressor (NCBI) | compare |
| b1712 | ihfA | -1.2 | -1.9 | integration host factor subunit alpha (NCBI) | compare |
| b3726 | pstA | -1.2 | -4.1 | phosphate transporter subunit (NCBI) | compare |
| b2531 | iscR | -1.2 | -1.7 | DNA-binding transcriptional repressor (NCBI) | compare |
| b1687 | ydiJ | -1.2 | -7.8 | predicted FAD-linked oxidoreductase (NCBI) | compare |
| b0630 | lipB | -1.1 | -1.3 | protein of lipoate biosynthesis (VIMSS) | compare |
| b3346 | yheO | -1.1 | -7.2 | orf, hypothetical protein (VIMSS) | compare |
| b3290 | trkA | -1.1 | -2.6 | potassium transporter peripheral membrane component (NCBI) | compare |
| b0740 | tolB | -1.1 | -4.4 | translocation protein TolB precursor (NCBI) | compare |
| b2286 | nuoC | -1.1 | -5.4 | NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) | compare |
| b3636 | rpmG | -1.1 | -1.8 | 50S ribosomal protein L33 (NCBI) | compare |
| b4535 | yniD | -1.1 | -1.6 | predicted protein (RefSeq) | compare |
| b0724 | sdhB | -1.1 | -5.5 | succinate dehydrogenase, FeS subunit (NCBI) | compare |
| b2284 | nuoF | -1.1 | -3.9 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b1351 | racC | -1.1 | -0.7 | Rac prophage; predicted protein (NCBI) | compare |
| b2506 | yfgI | -1.1 | -2.3 | hypothetical protein (NCBI) | compare |
| b1263 | trpD | -1.1 | -1.9 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b3863 | polA | -1.1 | -1.4 | DNA polymerase I (NCBI) | compare |
| b0676 | nagC | -1.0 | -6.6 | DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) | compare |
| b2277 | nuoM | -1.0 | -5.7 | NADH dehydrogenase subunit M (NCBI) | compare |
| b0928 | aspC | -1.0 | -5.6 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b3082 | ygjM | -1.0 | -1.8 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2683 | ygaH | -1.0 | -3.8 | predicted inner membrane protein (NCBI) | compare |
| b0890 | ftsK | -1.0 | -4.3 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b1573 | ydfC | -1.0 | -2.0 | Qin prophage; predicted protein (RefSeq) | compare |
| b1363 | trkG | -1.0 | -1.0 | Rac prophage; potassium transporter subunit (NCBI) | compare |
| b3742 | mioC | -1.0 | -5.4 | flavodoxin (NCBI) | compare |
| b3784 | rfe | -1.0 | -7.3 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b0075 | leuL | -1.0 | -2.8 | leu operon leader peptide (NCBI) | compare |
| b2071 | yegJ | -1.0 | -1.7 | hypothetical protein (NCBI) | compare |
| b0738 | tolR | -1.0 | -3.0 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b1536 | ydeI | -1.0 | -1.1 | hypothetical protein (NCBI) | compare |
| b1607 | ydgC | -1.0 | -1.5 | conserved inner membrane protein associated with alginate biosynthesis (NCBI) | compare |
| b3493 | pitA | -1.0 | -5.5 | phosphate transporter, low-affinity (NCBI) | compare |
| b4396 | rob | -1.0 | -6.6 | DNA-binding transcriptional activator (NCBI) | compare |
| b1831 | proQ | -1.0 | -3.8 | putative solute/DNA competence effector (NCBI) | compare |
| b1506 | yneL | -1.0 | -1.7 | predicted transcriptional regulator (NCBI) | compare |
| b3226 | yhcK | -1.0 | -3.7 | putative FADA-type transcriptional regulator (VIMSS) | compare |
| b1150 | ymfR | -1.0 | -1.1 | e14 prophage; predicted protein (NCBI) | compare |
| b1084 | rne | -1.0 | -4.2 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b0585 | fes | -1.0 | -5.1 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b1264 | trpE | -0.9 | -2.8 | anthranilate synthase component I (NCBI) | compare |
| b2814 | metZ | -0.9 | -1.5 | tRNA-Met (NCBI) | compare |
| b1232 | purU | -0.9 | -5.1 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b0722 | sdhD | -0.9 | -3.7 | succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) | compare |
| b1658 | purR | -0.9 | -3.7 | DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) | compare |
| b3613 | yibP | -0.9 | -3.7 | putative membrane protein (VIMSS) | compare |
| b3609 | secB | -0.9 | -2.0 | export protein SecB (NCBI) | compare |