| | gene | name | fitness | t score | description | |
|---|
| b3390 | aroK | -4.3 | -4.2 | shikimate kinase I (NCBI) | compare |
| b1192 | ldcA | -3.8 | -8.2 | L,D-carboxypeptidase A (NCBI) | compare |
| b0200 | gmhB | -3.3 | -3.2 | hypothetical protein (NCBI) | compare |
| b2763 | cysI | -3.1 | -9.4 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b2752 | cysD | -3.1 | -9.0 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b2762 | cysH | -3.1 | -11.2 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b0033 | carB | -3.0 | -16.8 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b2476 | purC | -3.0 | -4.1 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b2414 | cysK | -3.0 | -13.6 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b2751 | cysN | -3.0 | -8.7 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b0564 | appY | -3.0 | -1.6 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b3172 | argG | -3.0 | -14.2 | argininosuccinate synthase (NCBI) | compare |
| b0004 | thrC | -2.9 | -13.4 | threonine synthase (NCBI) | compare |
| b4383 | deoB | -2.9 | -10.5 | phosphopentomutase (NCBI) | conserved |
| b2329 | aroC | -2.9 | -6.9 | chorismate synthase (NCBI) | compare |
| b0522 | purK | -2.8 | -10.4 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b2023 | hisH | -2.8 | -9.0 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b2750 | cysC | -2.8 | -6.1 | adenylylsulfate kinase (NCBI) | compare |
| b3368 | cysG | -2.8 | -16.5 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b0908 | aroA | -2.8 | -11.3 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b0071 | leuD | -2.8 | -9.0 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b1693 | aroD | -2.8 | -9.2 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b2764 | cysJ | -2.8 | -11.6 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b2019 | hisG | -2.8 | -6.4 | ATP phosphoribosyltransferase (NCBI) | compare |
| b3389 | aroB | -2.8 | -11.9 | 3-dehydroquinate synthase (NCBI) | compare |
| b3831 | udp | -2.7 | -14.9 | uridine phosphorylase (NCBI) | conserved |
| b4013 | metA | -2.7 | -11.4 | homoserine O-succinyltransferase (NCBI) | compare |
| b3939 | metB | -2.7 | -14.1 | cystathionine gamma-synthase (NCBI) | compare |
| b2557 | purL | -2.7 | -11.7 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b3770 | ilvE | -2.7 | -13.5 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b3771 | ilvD | -2.7 | -14.5 | dihydroxy-acid dehydratase (NCBI) | compare |
| b2499 | purM | -2.7 | -6.9 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b2846 | yqeH | -2.7 | -1.8 | orf, hypothetical protein (VIMSS) | compare |
| b3671 | ilvB | -2.7 | -15.1 | acetolactate synthase large subunit (NCBI) | compare |
| b2600 | tyrA | -2.7 | -9.7 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b0073 | leuB | -2.7 | -11.7 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b2026 | hisI | -2.6 | -6.9 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b3941 | metF | -2.6 | -10.9 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b3870 | glnA | -2.6 | -4.3 | glutamine synthetase (NCBI) | compare |
| b3281 | aroE | -2.6 | -15.9 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b2340 | sixA | -2.6 | -4.8 | phosphohistidine phosphatase (NCBI) | compare |
| b0907 | serC | -2.6 | -8.8 | phosphoserine aminotransferase (NCBI) | compare |
| b0386 | proC | -2.6 | -8.7 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b3957 | argE | -2.6 | -14.4 | acetylornithine deacetylase (NCBI) | compare |
| b3959 | argB | -2.6 | -10.8 | acetylglutamate kinase (RefSeq) | compare |
| b3956 | ppc | -2.6 | -17.4 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b2567 | rnc | -2.6 | -1.7 | ribonuclease III (NCBI) | compare |
| b2020 | hisD | -2.5 | -10.3 | histidinol dehydrogenase (NCBI) | compare |
| b3774 | ilvC | -2.5 | -14.6 | ketol-acid reductoisomerase (NCBI) | compare |
| b4006 | purH | -2.5 | -14.4 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b3772 | ilvA | -2.5 | -13.4 | threonine dehydratase (NCBI) | compare |
| b0002 | thrA | -2.5 | -12.8 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b4702 | mgtL | -2.5 | -3.0 | regulatory leader peptide for mgtA (NCBI) | compare |
| b0888 | trxB | -2.5 | -6.8 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b2021 | hisC | -2.5 | -9.8 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b4005 | purD | -2.5 | -12.6 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b0242 | proB | -2.5 | -9.5 | gamma-glutamyl kinase (NCBI) | compare |
| b0032 | carA | -2.5 | -9.7 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b3008 | metC | -2.5 | -10.5 | cystathionine beta-lyase (NCBI) | compare |
| b2025 | hisF | -2.5 | -7.0 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b0243 | proA | -2.5 | -8.6 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b3958 | argC | -2.4 | -13.3 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b0072 | leuC | -2.4 | -13.3 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b1260 | trpA | -2.4 | -4.7 | tryptophan synthase subunit alpha (NCBI) | compare |
| b1263 | trpD | -2.4 | -2.7 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b3773 | ilvY | -2.4 | -9.6 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2022 | hisB | -2.4 | -7.8 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b4388 | serB | -2.4 | -8.4 | 3-phosphoserine phosphatase (NCBI) | compare |
| b0003 | thrB | -2.4 | -8.8 | homoserine kinase (NCBI) | compare |
| b1261 | trpB | -2.4 | -4.0 | tryptophan synthase subunit beta (NCBI) | compare |
| b3839 | tatC | -2.4 | -10.3 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0720 | gltA | -2.4 | -9.0 | citrate synthase (NCBI) | compare |
| b2312 | purF | -2.3 | -7.6 | amidophosphoribosyltransferase (NCBI) | compare |
| b0074 | leuA | -2.3 | -10.3 | 2-isopropylmalate synthase (NCBI) | compare |
| b2838 | lysA | -2.3 | -10.6 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b0726 | sucA | -2.3 | -6.5 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b3672 | ivbL | -2.3 | -3.3 | ilvB operon leader peptide (NCBI) | compare |
| b0114 | aceE | -2.3 | -1.5 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b2818 | argA | -2.2 | -9.5 | N-acetylglutamate synthase (NCBI) | compare |
| b3960 | argH | -2.2 | -12.2 | argininosuccinate lyase (NCBI) | compare |
| b2024 | hisA | -2.2 | -4.1 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b0523 | purE | -2.2 | -6.6 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b2913 | serA | -2.1 | -7.8 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b2479 | gcvR | -2.1 | -7.4 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b3764 | yifE | -2.1 | -5.9 | hypothetical protein (NCBI) | compare |
| b3916 | pfkA | -2.0 | -5.1 | 6-phosphofructokinase (NCBI) | compare |
| b4214 | cysQ | -1.9 | -11.2 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b4242 | mgtA | -1.9 | -10.7 | magnesium transporter (NCBI) | compare |
| b3781 | trxA | -1.9 | -4.3 | thioredoxin 1 (VIMSS) | compare |
| b4480 | hdfR | -1.9 | -8.3 | transcriptional regulator HdfR (NCBI) | compare |
| b2784 | relA | -1.9 | -10.4 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b2839 | lysR | -1.8 | -5.4 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2143 | cdd | -1.8 | -3.3 | cytidine deaminase (NCBI) | conserved |
| b3728 | pstS | -1.8 | -3.6 | phosphate transporter subunit (NCBI) | compare |
| b1291 | sapD | -1.8 | -2.9 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1104 | ycfL | -1.7 | -2.5 | hypothetical protein (NCBI) | compare |
| b1262 | trpC | -1.7 | -5.0 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b1264 | trpE | -1.7 | -5.0 | anthranilate synthase component I (NCBI) | compare |
| b0113 | pdhR | -1.7 | -4.9 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b1882 | cheY | -1.7 | -1.0 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b3792 | wzxE | -1.7 | -8.4 | O-antigen translocase (NCBI) | compare |
| b2528 | iscA | -1.7 | -3.3 | iron-sulfur cluster assembly protein (NCBI) | compare |
| b0145 | dksA | -1.7 | -3.7 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b1332 | ynaJ | -1.7 | -1.3 | predicted inner membrane protein (NCBI) | compare |
| b0049 | apaH | -1.7 | -4.6 | diadenosinetetraphosphatase (NCBI) | compare |
| b3082 | ygjM | -1.7 | -2.7 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3213 | gltD | -1.7 | -9.4 | glutamate synthase, 4Fe-4S protein, small subunit (NCBI) | compare |
| b1709 | btuD | -1.6 | -1.9 | vitamin B12-transporter ATPase (NCBI) | compare |
| b1129 | phoQ | -1.6 | -1.1 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b4676 | yoaK | -1.6 | -0.9 | expressed protein (RefSeq) | compare |
| b1363 | trkG | -1.5 | -1.1 | Rac prophage; potassium transporter subunit (NCBI) | compare |
| b0439 | lon | -1.5 | -5.9 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b4146 | yjeK | -1.5 | -3.2 | predicted lysine aminomutase (NCBI) | compare |
| b2935 | tktA | -1.5 | -2.9 | transketolase 1, thiamin-binding (NCBI) | compare |
| b2501 | ppk | -1.5 | -9.0 | polyphosphate kinase (NCBI) | compare |
| b3469 | zntA | -1.5 | -7.9 | zinc, cobalt and lead efflux system (NCBI) | compare |
| b3212 | gltB | -1.5 | -11.8 | glutamate synthase, large subunit (NCBI) | compare |
| b2599 | pheA | -1.5 | -6.1 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b3741 | gidA | -1.5 | -5.4 | glucose-inhibited division protein A (NCBI) | compare |
| b1429 | tehA | -1.5 | -2.1 | potassium-tellurite ethidium and proflavin transporter (NCBI) | compare |
| b2531 | iscR | -1.5 | -2.0 | DNA-binding transcriptional repressor (NCBI) | compare |
| b0080 | fruR | -1.5 | -6.3 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b1712 | ihfA | -1.5 | -2.5 | integration host factor subunit alpha (NCBI) | compare |
| b1165 | ymgA | -1.4 | -1.0 | hypothetical protein (NCBI) | compare |
| b3806 | cyaA | -1.3 | -4.3 | adenylate cyclase (NCBI) | compare |
| b1290 | sapF | -1.3 | -1.9 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3290 | trkA | -1.3 | -3.1 | potassium transporter peripheral membrane component (NCBI) | compare |
| b3962 | udhA | -1.3 | -6.0 | putative oxidoreductase (VIMSS) | compare |
| b4066 | yjcF | -1.3 | -0.8 | hypothetical protein (NCBI) | compare |
| b4590 | ybfK | -1.3 | -1.5 | hypothetical protein (RefSeq) | compare |
| b2313 | cvpA | -1.3 | -3.0 | membrane protein required for colicin V production (NCBI) | compare |
| b4410 | ecnA | -1.2 | -1.9 | entericidin A membrane lipoprotein, antidote entericidin B (NCBI) | compare |
| b3386 | rpe | -1.2 | -0.8 | ribulose-phosphate 3-epimerase (NCBI) | compare |
| b0739 | tolA | -1.2 | -4.6 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b2500 | purN | -1.2 | -5.9 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b0722 | sdhD | -1.2 | -4.3 | succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) | compare |
| b3204 | ptsN | -1.2 | -4.1 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b1536 | ydeI | -1.2 | -1.5 | hypothetical protein (NCBI) | compare |
| b4647 | mokA | -1.2 | -0.8 | no description | compare |
| b0890 | ftsK | -1.2 | -5.2 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b1130 | phoP | -1.2 | -1.5 | DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) | compare |
| b4155 | yjeA | -1.1 | -0.8 | putative lysyl-tRNA synthetase (VIMSS) | compare |
| b3169 | nusA | -1.1 | -3.5 | transcription elongation factor NusA (NCBI) | compare |
| b1676 | pykF | -1.1 | -3.4 | pyruvate kinase (NCBI) | compare |
| b1161 | ycgX | -1.1 | -1.3 | hypothetical protein (NCBI) | compare |
| b1784 | yeaH | -1.1 | -7.1 | yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b4171 | miaA | -1.1 | -3.3 | tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) | compare |
| b2071 | yegJ | -1.1 | -1.9 | hypothetical protein (NCBI) | compare |
| b2422 | cysA | -1.1 | -5.7 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b0500 | ybbD | -1.1 | -0.7 | hypothetical protein (RefSeq) | compare |
| b4685 | yrbN | -1.1 | -2.9 | expressed protein (RefSeq) | compare |
| b0630 | lipB | -1.1 | -1.4 | protein of lipoate biosynthesis (VIMSS) | compare |
| b0388 | aroL | -1.1 | -3.0 | shikimate kinase II (NCBI) | compare |
| b3250 | mreC | -1.0 | -1.0 | cell wall structural complex MreBCD transmembrane component MreC (NCBI) | compare |
| b0585 | fes | -1.0 | -5.0 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b4045 | yjbJ | -1.0 | -1.5 | predicted stress response protein (NCBI) | compare |
| b0889 | lrp | -1.0 | -1.7 | DNA-binding transcriptional dual regulator, leucine-binding (NCBI) | compare |
| b1269 | rluB | -1.0 | -4.3 | 23S rRNA pseudouridylate synthase (NCBI) | compare |
| b4048 | yjbM | -1.0 | -1.6 | hypothetical protein (NCBI) | compare |
| b1505 | ydeT | -1.0 | -1.4 | hypothetical protein (RefSeq) | compare |
| b2330 | yfcB | -1.0 | -1.8 | putative adenine-specific methylase (VIMSS) | compare |
| b4177 | purA | -1.0 | -1.3 | adenylosuccinate synthetase (NCBI) | compare |
| b3053 | glnE | -1.0 | -6.2 | fused deadenylyltransferase/adenylyltransferase for glutamine synthetase (NCBI) | compare |
| b3706 | trmE | -1.0 | -3.8 | tRNA modification GTPase (NCBI) | compare |
| b1292 | sapC | -1.0 | -1.5 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3849 | trkH | -1.0 | -6.1 | potassium transporter (NCBI) | compare |
| b0767 | ybhE | -1.0 | -2.4 | 6-phosphogluconolactonase (NCBI) | compare |
| b1188 | ycgB | -0.9 | -4.3 | ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b3021 | ygiT | -0.9 | -2.1 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b1765 | ydjA | -0.9 | -1.1 | predicted oxidoreductase (NCBI) | compare |
| b1874 | cutC | -0.9 | -2.2 | copper homeostasis protein (NCBI) | compare |
| b2853 | ygeI | -0.9 | -0.6 | hypothetical protein (NCBI) | compare |
| b0738 | tolR | -0.9 | -2.7 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b2259 | pmrD | -0.9 | -1.3 | polymyxin resistance protein B (VIMSS) | compare |
| b4215 | ytfI | -0.9 | -1.7 | hypothetical protein (NCBI) | compare |
| b1036 | ycdZ | -0.9 | -4.5 | orf, hypothetical protein (VIMSS) | compare |
| b0075 | leuL | -0.9 | -3.1 | leu operon leader peptide (NCBI) | compare |
| b1545 | pinQ | -0.9 | -0.3 | Qin prophage; predicted site-specific recombinase (NCBI) | compare |
| b3035 | tolC | -0.9 | -5.0 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) | compare |
| b4202 | rpsR | -0.9 | -1.6 | 30S ribosomal protein S18 (NCBI) | compare |
| b3811 | xerC | -0.9 | -2.0 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b3623 | rfaK | -0.9 | -2.2 | lipopolysaccharide core biosynthesis (NCBI) | compare |
| b0122 | yacC | -0.9 | -2.5 | orf, hypothetical protein (VIMSS) | compare |
| b0167 | glnD | -0.9 | -2.9 | PII uridylyl-transferase (NCBI) | compare |
| b0688 | pgm | -0.9 | -3.7 | phosphoglucomutase (NCBI) | compare |
| b0234 | yafP | -0.9 | -1.5 | predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) | compare |
| b1594 | dgsA | -0.9 | -3.1 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3791 | rffA | -0.9 | -5.5 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b4179 | vacB | -0.9 | -4.4 | putative enzyme (VIMSS) | compare |
| b1783 | yeaG | -0.9 | -5.4 | yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b2423 | cysW | -0.8 | -3.7 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b0840 | deoR | -0.8 | -3.1 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3650 | spoT | -0.8 | -4.0 | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | compare |
| b1232 | purU | -0.8 | -3.4 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b2285 | nuoE | -0.8 | -1.6 | NADH dehydrogenase subunit E (NCBI) | compare |
| b3162 | deaD | -0.8 | -2.9 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b3398 | yrfF | -0.8 | -2.6 | predicted inner membrane protein (NCBI) | compare |
| b3726 | pstA | -0.8 | -2.3 | phosphate transporter subunit (NCBI) | compare |
| b1600 | mdtJ | -0.8 | -1.8 | multidrug efflux system transporter (NCBI) | compare |
| b1058 | yceO | -0.8 | -0.4 | hypothetical protein (NCBI) | compare |