Experiment set66S401 for Escherichia coli BW25113

Compare to:

TP4

200 most important genes:

  gene name fitness t score description  
b4246 pyrL -4.6 -3.4 pyrBI operon leader peptide (NCBI) compare
b1984 asnW -4.5 -1.6 tRNA-Asn (NCBI) compare
b3742 mioC -3.7 -3.9 flavodoxin (NCBI) compare
b3341 rpsG -3.7 -2.2 30S ribosomal protein S7 (NCBI) compare
b1493 gadB -3.5 -1.2 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b1429 tehA -3.5 -2.1 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1842 holE -3.4 -2.7 DNA polymerase III, theta subunit (NCBI) compare
b4603 rseX -3.3 -1.1 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b2576 srmB -2.8 -4.2 ATP-dependent RNA helicase (NCBI) compare
b0053 surA -2.7 -4.2 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3405 ompR -2.7 -4.8 osmolarity response regulator (NCBI) compare
b0547 ybcN -2.6 -4.5 DLP12 prophage; predicted protein (NCBI) compare
b3002 yqhA -2.5 -2.3 hypothetical protein (NCBI) compare
b1361 ydaW -2.5 -0.8 orf, hypothetical protein (VIMSS) compare
b0145 dksA -2.5 -3.0 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1709 btuD -2.4 -1.1 vitamin B12-transporter ATPase (NCBI) compare
b0739 tolA -2.4 -1.7 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3229 sspA -2.4 -3.3 stringent starvation protein A (NCBI) compare
b4042 dgkA -2.4 -1.6 diacylglycerol kinase (NCBI) compare
b2330 yfcB -2.4 -1.6 putative adenine-specific methylase (VIMSS) compare
b0014 dnaK -2.4 -1.9 molecular chaperone DnaK (NCBI) compare
b1724 ydiZ -2.3 -2.2 hypothetical protein (NCBI) compare
b0142 folK -2.3 -0.8 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b4151 frdD -2.3 -2.5 fumarate reductase subunit D (NCBI) compare
b2906 visC -2.3 -5.2 hypothetical protein (NCBI) compare
b0738 tolR -2.3 -1.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2168 fruK -2.2 -1.8 1-phosphofructokinase (NCBI) compare
b1686 ydiI -2.2 -1.5 hypothetical protein (NCBI) compare
b2188 yejM -2.1 -7.8 predicted hydrolase, inner membrane (NCBI) compare
b3005 exbD -2.1 -3.3 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b4402 yjjY -2.1 -1.0 hypothetical protein (NCBI) compare
b4701 sokX -2.1 -1.0 sok-related sRNA, function unknown (RefSeq) compare
b0584 fepA -2.0 -8.1 iron-enterobactin outer membrane transporter (NCBI) compare
b1848 yebG -2.0 -1.4 conserved protein regulated by LexA (NCBI) compare
b1286 rnb -2.0 -2.7 exoribonuclease II (NCBI) compare
b2620 smpB -2.0 -1.4 SsrA-binding protein (NCBI) compare
b2804 fucU -2.0 -2.4 L-fucose mutarotase (NCBI) compare
b3838 tatB -2.0 -6.6 sec-independent translocase (NCBI) compare
b0660 ybeZ -2.0 -3.4 predicted protein with nucleoside triphosphate hydrolase domain (RefSeq) compare
b0740 tolB -2.0 -4.5 translocation protein TolB precursor (NCBI) compare
b1175 minD -2.0 -4.3 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b1358 ydaT -2.0 -1.3 Rac prophage; predicted protein (NCBI) compare
b3162 deaD -2.0 -5.4 inducible ATP-independent RNA helicase (VIMSS) compare
b2912 ygfA -2.0 -3.4 putative ligase (VIMSS) compare
b3871 bipA -2.0 -7.6 GTP-binding protein (NCBI) compare
b1086 rluC -2.0 -3.8 23S rRNA pseudouridylate synthase (NCBI) compare
b4178 yjeB -1.9 -4.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b1863 ruvC -1.9 -1.3 Holliday junction resolvase (NCBI) compare
b0082 mraW -1.9 -2.9 S-adenosyl-methyltransferase (NCBI) compare
b1251 yciI -1.9 -3.0 orf, hypothetical protein (VIMSS) compare
b0858 ybjO -1.9 -1.8 predicted inner membrane protein (NCBI) compare
b3764 yifE -1.9 -3.4 hypothetical protein (NCBI) compare
b3787 rffD -1.9 -6.4 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b0564 appY -1.9 -0.8 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b1677 lpp -1.8 -1.8 murein lipoprotein (NCBI) compare
b3545 proK -1.8 -1.6 tRNA-Pro (NCBI) compare
b2248 yfaX -1.8 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b2083 yegZ -1.7 -2.0 orf, hypothetical protein (VIMSS) compare
b4515 ybgT -1.7 -1.3 hypothetical protein (NCBI) compare
b0706 ybfD -1.7 -2.0 hypothetical protein (NCBI) compare
b3611 yibN -1.7 -3.1 predicted rhodanese-related sulfurtransferase (NCBI) compare
b1684 sufA -1.7 -1.8 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b2830 nudH -1.7 -1.1 dinucleoside polyphosphate hydrolase (NCBI) compare
b2058 wcaB -1.7 -1.0 predicted acyl transferase (NCBI) compare
b3839 tatC -1.7 -5.2 TatABCE protein translocation system subunit (NCBI) compare
b4179 vacB -1.7 -5.2 putative enzyme (VIMSS) compare
b2959 yggL -1.6 -2.4 orf, hypothetical protein (VIMSS) compare
b4171 miaA -1.6 -3.1 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b2501 ppk -1.6 -5.1 polyphosphate kinase (NCBI) compare
b3784 rfe -1.6 -6.0 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b1765 ydjA -1.6 -0.8 predicted oxidoreductase (NCBI) compare
b1550 b1550 -1.6 -1.3 orf, hypothetical protein (VIMSS) compare
b3529 yhjK -1.6 -8.0 predicted diguanylate cyclase (RefSeq) conserved
b3613 yibP -1.6 -2.1 putative membrane protein (VIMSS) compare
b4363 yjjB -1.6 -2.0 conserved inner membrane protein (RefSeq) compare
b4676 yoaK -1.5 -0.7 expressed protein (RefSeq) compare
b0263 afuB -1.5 -1.1 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b2314 dedD -1.5 -1.9 putative lipoprotein (VIMSS) compare
b4596 yciZ -1.5 -1.4 hypothetical protein (RefSeq) compare
b3021 ygiT -1.5 -1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b2567 rnc -1.5 -1.0 ribonuclease III (NCBI) compare
b4480 hdfR -1.5 -2.7 transcriptional regulator HdfR (NCBI) compare
b1334 fnr -1.5 -1.9 DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) compare
b0232 yafN -1.4 -0.7 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3181 greA -1.4 -3.2 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b4702 mgtL -1.4 -1.2 regulatory leader peptide for mgtA (NCBI) compare
b3794 rffM -1.4 -3.4 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b3026 qseC -1.4 -2.6 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0439 lon -1.4 -4.1 DNA-binding ATP-dependent protease La (NCBI) compare
b4585 sroB -1.4 -1.1 Novel sRNA, function unknown (RefSeq) compare
b1476 fdnI -1.4 -0.8 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b3006 exbB -1.4 -4.0 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b4460 araH -1.4 -0.9 fused L-arabinose transporter subunits of ABC superfamily: membrane components (RefSeq) compare
b1600 mdtJ -1.4 -1.3 multidrug efflux system transporter (NCBI) compare
b3741 gidA -1.3 -2.7 glucose-inhibited division protein A (NCBI) compare
b4535 yniD -1.3 -1.2 predicted protein (RefSeq) compare
b2807 ygdD -1.3 -2.2 conserved inner membrane protein (NCBI) compare
b0920 ycbC -1.3 -2.8 conserved inner membrane protein (NCBI) compare
b2506 yfgI -1.3 -2.1 hypothetical protein (NCBI) compare
b3426 glpD -1.3 -2.6 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b0178 hlpA -1.3 -2.6 periplasmic chaperone (NCBI) compare
b3785 wzzE -1.3 -6.6 putative transport protein (VIMSS) compare
b0141 yadN -1.3 -4.7 predicted fimbrial-like adhesin protein (NCBI) compare
b3555 yiaG -1.3 -2.0 predicted transcriptional regulator (NCBI) compare
b3205 yhbJ -1.3 -2.6 hypothetical protein (NCBI) compare
b1192 ldcA -1.3 -2.2 L,D-carboxypeptidase A (NCBI) compare
b0736 ybgC -1.3 -2.2 predicted acyl-CoA thioesterase (NCBI) compare
b2938 speA -1.3 -5.0 arginine decarboxylase (NCBI) compare
b2444 yffM -1.3 -1.3 CPZ-55 prophage; predicted protein (NCBI) compare
b1988 nac -1.3 -2.6 DNA-binding transcriptional dual regulator of nitrogen assimilation (NCBI) compare
b1269 rluB -1.2 -2.4 23S rRNA pseudouridylate synthase (NCBI) compare
b1298 ycjL -1.2 -1.8 probable amidotransferase subunit (VIMSS) compare
b2061 wzb -1.2 -1.5 protein-tyrosine phosphatase (NCBI) compare
b1860 ruvB -1.2 -0.8 Holliday junction DNA helicase B (NCBI) compare
b0741 pal -1.2 -2.7 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1676 pykF -1.2 -2.4 pyruvate kinase (NCBI) compare
b2617 smpA -1.2 -1.6 small membrane protein A (VIMSS) compare
b2279 nuoK -1.2 -1.4 NADH dehydrogenase subunit K (NCBI) compare
b2754 ygbF -1.2 -2.2 orf, hypothetical protein (VIMSS) compare
b2319 usg -1.2 -2.1 hypothetical protein (NCBI) compare
b4697 yrdF -1.2 -2.7 no description compare
b2937 speB -1.2 -2.8 agmatinase (NCBI) compare
b3150 yraP -1.2 -3.7 hypothetical protein (NCBI) compare
b1013 ycdC -1.2 -1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b0623 cspE -1.2 -0.8 cold shock protein E (NCBI) compare
b1355 b1355 -1.2 -1.8 orf, hypothetical protein (VIMSS) compare
b3791 rffA -1.2 -4.1 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1861 ruvA -1.2 -0.8 Holliday junction DNA helicase motor protein (NCBI) compare
b4146 yjeK -1.2 -1.6 predicted lysine aminomutase (NCBI) compare
b0678 nagB -1.1 -1.7 glucosamine-6-phosphate deaminase (NCBI) compare
b2603 yfiR -1.1 -3.2 hypothetical protein (NCBI) compare
b3844 fre -1.1 -2.9 NAD(P)H-flavin reductase (NCBI) compare
b4685 yrbN -1.1 -2.0 expressed protein (RefSeq) compare
b4570 lomR -1.1 -1.2 no description compare
b0888 trxB -1.1 -1.6 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b4589 ylcI -1.1 -1.3 hypothetical protein (RefSeq) compare
b4648 ysaC -1.1 -1.9 no description compare
b0604 dsbG -1.1 -2.2 thiol:disulfide interchange protein (VIMSS) compare
b2699 recA -1.1 -0.7 recombinase A (NCBI) compare
b0001 thrL -1.1 -1.3 thr operon leader peptide (NCBI) compare
b1109 ndh -1.1 -2.2 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b3166 truB -1.1 -2.3 tRNA pseudouridine synthase B (NCBI) compare
b0161 degP -1.1 -3.8 serine endoprotease (protease Do), membrane-associated (NCBI) compare
b0143 pcnB -1.1 -3.2 poly(A) polymerase I (VIMSS) compare
b0877 ybjX -1.1 -2.8 hypothetical protein (NCBI) compare
b1711 btuC -1.1 -2.6 vtamin B12-transporter permease (NCBI) compare
b2187 yejL -1.1 -1.9 hypothetical protein (NCBI) compare
b4529 ydbJ -1.1 -0.6 hypothetical protein (NCBI) compare
b0990 cspG -1.1 -0.7 DNA-binding transcriptional regulator (NCBI) compare
b1850 eda -1.1 -1.5 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b1063 yceB -1.0 -1.1 predicted lipoprotein (NCBI) compare
b2911 ssrS -1.0 -1.0 6S regulatory RNA (NCBI) compare
b0015 dnaJ -1.0 -4.0 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b1028 ymdE -1.0 -3.0 orf, hypothetical protein (VIMSS) compare
b4470 yhaM -1.0 -3.4 hypothetical protein (NCBI) compare
b3261 fis -1.0 -0.7 DNA-binding protein Fis (NCBI) compare
b3071 yqjI -1.0 -2.2 predicted transcriptional regulator (NCBI) compare
b0998 torD -1.0 -0.8 chaperone protein TorD (NCBI) compare
b2457 cchA -1.0 -2.5 detox protein (VIMSS) compare
b2935 tktA -1.0 -1.0 transketolase 1, thiamin-binding (NCBI) compare
b1970 yedX -1.0 -2.6 hypothetical protein (NCBI) compare
b1259 yciG -1.0 -0.9 orf, hypothetical protein (VIMSS) compare
b2252 ais -1.0 -3.2 hypothetical protein (NCBI) compare
b2111 yehD -1.0 -1.6 predicted fimbrial-like adhesin protein (NCBI) compare
b1642 slyA -1.0 -1.0 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b1663 mdtK -1.0 -3.7 multidrug efflux protein NorM (NCBI) compare
b3469 zntA -1.0 -3.8 zinc, cobalt and lead efflux system (NCBI) compare
b1877 yecT -1.0 -1.1 orf, hypothetical protein (VIMSS) compare
b1948 fliP -1.0 -2.3 flagellar biosynthesis protein P (NCBI) compare
b3446 yrhB -1.0 -3.5 hypothetical protein (NCBI) compare
b4631 ykgQ -1.0 -1.1 no description compare
b0737 tolQ -1.0 -1.3 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4558 yifL -1.0 -2.2 predicted lipoprotein (NCBI) compare
b1291 sapD -1.0 -1.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3979 thrT -1.0 -0.3 tRNA-Thr (NCBI) compare
b4451 ryhB -1.0 -0.9 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b1762 b1762 -1.0 -1.3 orf, hypothetical protein (VIMSS) compare
b1871 yecP -0.9 -1.5 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b1380 ldhA -0.9 -1.2 D-lactate dehydrogenase (NCBI) compare
b2953 yggU -0.9 -0.7 orf, hypothetical protein (VIMSS) compare
b1918 yecS -0.9 -0.7 predicted transporter subunit: membrane component of ABC superfamily (NCBI) compare
b3811 xerC -0.9 -1.1 site-specific tyrosine recombinase XerC (NCBI) compare
b3628 rfaB -0.9 -4.8 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b1731 cedA -0.9 -2.1 cell division modulator (RefSeq) compare
b1332 ynaJ -0.9 -0.4 predicted inner membrane protein (NCBI) compare
b0436 tig -0.9 -2.5 trigger factor (NCBI) compare
b0450 glnK -0.9 -1.5 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b1085 b1085 -0.9 -0.6 orf, hypothetical protein (VIMSS) compare
b1607 ydgC -0.9 -0.6 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b2114 metG -0.9 -1.2 methionyl-tRNA synthetase (NCBI) compare
b1176 minC -0.9 -1.9 septum formation inhibitor (NCBI) compare
b4593 ymgI -0.9 -0.6 hypothetical protein (RefSeq) compare
b2572 rseA -0.9 -2.3 anti-sigma factor (NCBI) compare
b1698 ydiR -0.9 -2.1 predicted electron transfer flavoprotein, FAD-binding (NCBI) compare
b0300 ykgA -0.9 -1.9 putative ARAC-type regulatory protein (VIMSS) compare
b3933 ftsN -0.9 -3.4 essential cell division protein (NCBI) compare
b1482 osmC -0.9 -1.3 osmotically inducible, stress-inducible membrane protein (NCBI) compare
b3024 ygiW -0.9 -1.9 hypothetical protein (NCBI) compare
b3169 nusA -0.9 -1.3 transcription elongation factor NusA (NCBI) compare
b3500 gor -0.9 -1.0 glutathione reductase (NCBI) compare


Specific Phenotypes

For 9 genes in this experiment

For phage MOI 10 in Escherichia coli BW25113

For phage MOI 10 across organisms