Experiment set61S71 for Escherichia coli BW25113

Compare to:

Laval1374

200 most important genes:

  gene name fitness t score description  
b0196 rcsF -5.8 -11.1 predicted outer membrane protein, signal (NCBI) conserved
b0019 nhaA -5.1 -13.5 pH-dependent sodium/proton antiporter (NCBI) compare
b2217 rcsB -4.9 -11.1 DNA-binding response regulator in two-component regulatory system with RcsC and YojN (NCBI) compare
b0149 mrcB -4.1 -20.7 penicillin-binding protein 1b (NCBI) compare
b0683 fur -3.7 -2.5 ferric uptake regulator (NCBI) compare
b1192 ldcA -3.6 -7.7 L,D-carboxypeptidase A (NCBI) compare
b1105 ycfM -3.5 -5.1 predicted outer membrane lipoprotein (NCBI) compare
b2062 wza -3.4 -12.5 lipoprotein required for capsular polysaccharide translocation through the outer membrane (NCBI) compare
b2218 rcsC -3.3 -12.3 hybrid sensory kinase in two-component regulatory system with RcsB and YojN (RefSeq) compare
b0222 lpcA -3.2 -4.8 phosphoheptose isomerase (NCBI) compare
b2216 rcsD -3.1 -10.9 phosphotransfer intermediate protein in two-component regulatory system with RcsBC (NCBI) compare
b3500 gor -3.1 -3.6 glutathione reductase (NCBI) compare
b2056 wcaD -3.0 -11.5 predicted colanic acid polymerase (NCBI) compare
b3790 rffC -2.9 -8.4 TDP-fucosamine acetyltransferase (RefSeq) compare
b0737 tolQ -2.8 -4.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0386 proC -2.8 -8.3 pyrroline-5-carboxylate reductase (NCBI) compare
b2060 b2060 -2.7 -10.7 orf, hypothetical protein (VIMSS) compare
b3792 wzxE -2.7 -10.0 O-antigen translocase (NCBI) compare
b3026 qseC -2.7 -5.1 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1863 ruvC -2.6 -3.0 Holliday junction resolvase (NCBI) compare
b1855 lpxM -2.6 -7.3 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b4402 yjjY -2.6 -1.5 hypothetical protein (NCBI) compare
b2830 nudH -2.6 -2.4 dinucleoside polyphosphate hydrolase (NCBI) compare
b2046 wzxC -2.6 -10.4 colanic acid exporter (NCBI) compare
b2044 wcaL -2.5 -5.5 predicted glycosyl transferase (NCBI) compare
b0741 pal -2.4 -5.5 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b3842 rfaH -2.4 -8.1 transcriptional activator RfaH (NCBI) compare
b0439 lon -2.4 -6.9 DNA-binding ATP-dependent protease La (NCBI) compare
b3621 rfaC -2.3 -7.2 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b0436 tig -2.2 -10.7 trigger factor (NCBI) compare
b0740 tolB -2.2 -5.8 translocation protein TolB precursor (NCBI) compare
b1860 ruvB -2.2 -1.5 Holliday junction DNA helicase B (NCBI) compare
b3261 fis -2.2 -2.1 DNA-binding protein Fis (NCBI) compare
b4481 rffT -2.2 -6.7 4-alpha-L-fucosyltransferase (NCBI) compare
b2061 wzb -2.1 -3.3 protein-tyrosine phosphatase (NCBI) compare
b3916 pfkA -2.1 -3.6 6-phosphofructokinase (NCBI) compare
b1176 minC -2.0 -3.9 septum formation inhibitor (NCBI) compare
b3794 rffM -2.0 -8.8 putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) compare
b3052 rfaE -2.0 -7.2 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b3791 rffA -2.0 -9.3 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b3979 thrT -2.0 -0.8 tRNA-Thr (NCBI) compare
b2059 wcaA -1.9 -5.7 predicted glycosyl transferase (NCBI) compare
b0739 tolA -1.9 -4.4 cell envelope integrity inner membrane protein TolA (NCBI) compare
b3630 rfaP -1.9 -10.5 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b3613 yibP -1.9 -4.4 putative membrane protein (VIMSS) compare
b3229 sspA -1.9 -4.2 stringent starvation protein A (NCBI) compare
b4536 yobH -1.9 -4.7 hypothetical protein (NCBI) compare
b3021 ygiT -1.9 -2.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b3787 rffD -1.8 -10.5 UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) compare
b0243 proA -1.8 -8.9 gamma-glutamyl phosphate reductase (NCBI) compare
b4171 miaA -1.8 -3.7 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1236 galU -1.8 -5.8 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3631 rfaG -1.8 -13.0 glucosyltransferase I (NCBI) compare
b0242 proB -1.7 -7.2 gamma-glutamyl kinase (NCBI) compare
b2045 wcaK -1.7 -10.6 predicted pyruvyl transferase (NCBI) compare
b2498 upp -1.7 -4.1 uracil phosphoribosyltransferase (VIMSS) compare
b0585 fes -1.7 -6.4 enterobactin/ferric enterobactin esterase (NCBI) compare
b3426 glpD -1.7 -3.3 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b3786 rffE -1.7 -10.0 UDP-N-acetyl glucosamine-2-epimerase (NCBI) compare
b0738 tolR -1.7 -3.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2052 fcl -1.6 -4.0 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase/ GDP-4-dehydro-6-L-deoxygalactose reductase (NCBI) compare
b4398 creB -1.6 -8.8 DNA-binding response regulator in two-component regulatory system with CreC (NCBI) compare
b0053 surA -1.6 -6.6 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b3183 obgE -1.6 -1.5 GTPase involved in cell partioning and DNA repair (NCBI) compare
b3628 rfaB -1.6 -9.5 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b4399 creC -1.6 -8.8 sensory histidine kinase in two-component regulatory system with CreB or PhoB, regulator of the CreBC regulon (NCBI) compare
b3811 xerC -1.6 -2.1 site-specific tyrosine recombinase XerC (NCBI) compare
b3706 trmE -1.6 -5.8 tRNA modification GTPase (NCBI) compare
b3816 corA -1.5 -8.8 magnesium/nickel/cobalt transporter (NCBI) compare
b0957 ompA -1.5 -5.2 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3627 rfaI -1.5 -9.2 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase (NCBI) compare
b3619 rfaD -1.5 -4.6 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1332 ynaJ -1.5 -0.9 predicted inner membrane protein (NCBI) compare
b3181 greA -1.5 -5.2 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b0630 lipB -1.5 -1.9 protein of lipoate biosynthesis (VIMSS) compare
b1109 ndh -1.5 -4.7 respiratory NADH dehydrogenase 2/cupric reductase (NCBI) compare
b1677 lpp -1.5 -3.3 murein lipoprotein (NCBI) compare
b2571 rseB -1.5 -7.7 periplasmic negative regulator of sigmaE (NCBI) compare
b2318 truA -1.5 -3.1 tRNA pseudouridine synthase A (NCBI) compare
b3778 rep -1.5 -7.8 DNA helicase and single-stranded DNA-dependent ATPase (NCBI) compare
b2620 smpB -1.4 -1.6 SsrA-binding protein (NCBI) compare
b2028 ugd -1.4 -10.3 UDP-glucose 6-dehydrogenase (NCBI) compare
b2688 gshA -1.4 -5.7 glutamate--cysteine ligase (NCBI) compare
b0590 fepD -1.4 -7.4 iron-enterobactin transporter subunit (NCBI) compare
b2699 recA -1.4 -2.0 recombinase A (NCBI) compare
b4400 creD -1.4 -9.2 inner membrane protein (NCBI) compare
b3839 tatC -1.4 -5.9 TatABCE protein translocation system subunit (NCBI) compare
b2808 gcvA -1.4 -3.7 DNA-binding transcriptional dual regulator (NCBI) compare
b2501 ppk -1.3 -9.1 polyphosphate kinase (NCBI) compare
b1103 ycfF -1.3 -1.8 orf, hypothetical protein (VIMSS) compare
b2895 fldB -1.3 -4.0 flavodoxin 2 (NCBI) compare
b3741 gidA -1.3 -4.4 glucose-inhibited division protein A (NCBI) compare
b0888 trxB -1.3 -4.2 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b4585 sroB -1.3 -1.4 Novel sRNA, function unknown (RefSeq) compare
b0730 mngR -1.3 -2.2 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b0759 galE -1.2 -6.6 UDP-galactose-4-epimerase (VIMSS) compare
b1293 sapB -1.2 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2853 ygeI -1.2 -0.8 hypothetical protein (NCBI) compare
b3408 feoA -1.2 -8.2 ferrous iron transport protein A (NCBI) conserved
b0588 fepC -1.2 -6.1 iron-enterobactin transporter subunit (NCBI) compare
b3409 feoB -1.2 -10.1 ferrous iron transport protein B (NCBI) compare
b1175 minD -1.2 -5.3 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b1856 yebA -1.2 -6.1 orf, hypothetical protein (VIMSS) compare
b3784 rfe -1.1 -8.7 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) compare
b3162 deaD -1.1 -4.7 inducible ATP-independent RNA helicase (VIMSS) compare
b0441 ppiD -1.1 -8.2 peptidyl-prolyl cis-trans isomerase (rotamase D) (NCBI) compare
b0890 ftsK -1.1 -3.9 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2567 rnc -1.1 -1.0 ribonuclease III (NCBI) compare
b2513 yfgM -1.1 -4.6 hypothetical protein (NCBI) compare
b3386 rpe -1.1 -0.7 ribulose-phosphate 3-epimerase (NCBI) compare
b0589 fepG -1.1 -6.1 iron-enterobactin transporter subunit (NCBI) compare
b0677 nagA -1.1 -5.0 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b0592 fepB -1.1 -7.5 iron-enterobactin transporter subunit (NCBI) compare
b4155 yjeA -1.1 -0.7 putative lysyl-tRNA synthetase (VIMSS) compare
b2576 srmB -1.1 -2.6 ATP-dependent RNA helicase (NCBI) compare
b1279 yciS -1.1 -1.3 conserved inner membrane protein (NCBI) compare
b1882 cheY -1.1 -0.7 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b4042 dgkA -1.0 -2.2 diacylglycerol kinase (NCBI) compare
b4239 treC -1.0 -1.4 trehalose-6-P hydrolase (NCBI) compare
b0379 yaiY -1.0 -3.9 predicted inner membrane protein (NCBI) compare
b1506 yneL -1.0 -1.5 predicted transcriptional regulator (NCBI) compare
b4000 hupA -1.0 -4.2 HU, DNA-binding transcriptional regulator, alpha subunit (NCBI) compare
b2053 gmd -1.0 -3.6 GDP-D-mannose dehydratase, NAD(P)-binding (NCBI) compare
b3620 rfaF -1.0 -4.6 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b3624 rfaZ -1.0 -1.8 lipopolysaccharide core biosynthesis protein (NCBI) compare
b0471 ybaB -1.0 -2.8 hypothetical protein (NCBI) compare
b0726 sucA -1.0 -2.8 alpha-ketoglutarate decarboxylase (NCBI) compare
b2071 yegJ -1.0 -2.0 hypothetical protein (NCBI) compare
b3728 pstS -1.0 -2.7 phosphate transporter subunit (NCBI) compare
b4535 yniD -1.0 -1.5 predicted protein (RefSeq) compare
b1104 ycfL -1.0 -1.1 hypothetical protein (NCBI) compare
b2279 nuoK -1.0 -1.6 NADH dehydrogenase subunit K (NCBI) compare
b3387 dam -1.0 -7.4 DNA adenine methylase (NCBI) compare
b2617 smpA -1.0 -3.3 small membrane protein A (VIMSS) compare
b2435 amiA -0.9 -3.9 N-acetylmuramoyl-l-alanine amidase I (NCBI) compare
b0767 ybhE -0.9 -3.7 6-phosphogluconolactonase (NCBI) compare
b1850 eda -0.9 -1.9 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b4146 yjeK -0.9 -2.0 predicted lysine aminomutase (NCBI) compare
b4201 priB -0.9 -2.4 primosomal replication protein N (NCBI) compare
b0617 citD -0.9 -1.6 citrate lyase, acyl carrier (gamma) subunit (NCBI) compare
b3803 hemX -0.9 -5.9 predicted uroporphyrinogen III methylase (NCBI) compare
b2528 iscA -0.9 -0.8 iron-sulfur cluster assembly protein (NCBI) compare
b3405 ompR -0.9 -3.7 osmolarity response regulator (NCBI) compare
b4025 pgi -0.9 -5.7 glucose-6-phosphate isomerase (NCBI) compare
b1545 pinQ -0.9 -0.3 Qin prophage; predicted site-specific recombinase (NCBI) compare
b4191 ulaR -0.9 -3.5 DNA-binding transcriptional dual regulator (NCBI) compare
b4174 hflK -0.9 -5.8 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b2284 nuoF -0.9 -3.1 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b2935 tktA -0.9 -1.6 transketolase 1, thiamin-binding (NCBI) compare
b3169 nusA -0.9 -1.5 transcription elongation factor NusA (NCBI) compare
b0931 pncB -0.9 -3.5 nicotinate phosphoribosyltransferase (NCBI) compare
b1676 pykF -0.9 -3.3 pyruvate kinase (NCBI) compare
b3726 pstA -0.8 -3.9 phosphate transporter subunit (NCBI) compare
b0678 nagB -0.8 -3.3 glucosamine-6-phosphate deaminase (NCBI) compare
b4406 yaeP -0.8 -2.1 hypothetical protein (NCBI) compare
b4175 hflC -0.8 -5.2 modulator for HflB protease specific for phage lambda cII repressor (NCBI) compare
b3191 yrbB -0.8 -5.3 orf, hypothetical protein (VIMSS) compare
b3388 damX -0.8 -6.8 hypothetical protein (NCBI) compare
b3626 rfaJ -0.8 -3.4 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase (NCBI) compare
b2947 gshB -0.8 -3.0 glutathione synthetase (NCBI) compare
b3836 b3836 -0.8 -2.5 orf, hypothetical protein (VIMSS) compare
b1292 sapC -0.8 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2057 wcaC -0.8 -4.0 predicted glycosyl transferase (NCBI) compare
b1283 osmB -0.8 -3.3 lipoprotein (NCBI) compare
b2572 rseA -0.8 -2.8 anti-sigma factor (NCBI) compare
b4294 insA-7 -0.8 -2.3 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b3131 agaR -0.8 -2.5 DNA-binding transcriptional dual regulator (NCBI) compare
b1259 yciG -0.8 -1.7 orf, hypothetical protein (VIMSS) compare
b2579 yfiD -0.8 -2.2 pyruvate formate lyase subunit (NCBI) compare
b0438 clpX -0.8 -3.9 ATP-dependent protease ATP-binding subunit (NCBI) compare
b2569 lepA -0.8 -3.1 GTP-binding protein LepA (NCBI) compare
b2110 yehC -0.8 -1.0 predicted periplasmic pilin chaperone (NCBI) compare
b2426 ucpA -0.7 -2.1 putative oxidoreductase (VIMSS) compare
b3237 argR -0.7 -2.8 arginine repressor (NCBI) compare
b3629 rfaS -0.7 -2.5 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3193 yrbD -0.7 -5.2 predicted ABC-type organic solvent transporter (NCBI) compare
b3192 yrbC -0.7 -5.0 predicted ABC-type organic solvent transporter (NCBI) compare
b3889 yiiE -0.7 -1.7 predicted transcriptional regulator (RefSeq) compare
b1295 ymjA -0.7 -1.7 hypothetical protein (NCBI) compare
b2894 xerD -0.7 -0.9 site-specific tyrosine recombinase XerD (NCBI) compare
b0200 gmhB -0.7 -1.2 hypothetical protein (NCBI) compare
b3095 yqjA -0.7 -5.0 conserved inner membrane protein (NCBI) compare
b4172 hfq -0.7 -0.5 RNA-binding protein Hfq (NCBI) compare
b1696 ydiP -0.7 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b3802 hemY -0.7 -5.3 predicted protoheme IX synthesis protein (NCBI) compare
b1730 ydjO -0.7 -0.9 predicted protein (RefSeq) compare
b0020 nhaR -0.7 -4.9 DNA-binding transcriptional activator (NCBI) compare
b2276 nuoN -0.7 -3.3 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3658 selC -0.7 -2.2 tRNA-Sec (NCBI) compare
b3198 kdsC -0.7 -2.0 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b1762 b1762 -0.7 -1.5 orf, hypothetical protein (VIMSS) compare
b2168 fruK -0.7 -0.7 1-phosphofructokinase (NCBI) compare
b4100 phnH -0.7 -1.7 carbon-phosphorus lyase complex subunit (NCBI) compare
b3389 aroB -0.7 -4.4 3-dehydroquinate synthase (NCBI) compare
b0623 cspE -0.7 -1.2 cold shock protein E (NCBI) compare
b3035 tolC -0.7 -4.4 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b1291 sapD -0.7 -1.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3977 tyrU -0.7 -0.8 tRNA-Tyr (NCBI) compare
b3414 gntY -0.7 -3.0 predicted gluconate transport associated protein (NCBI) compare
b2317 dedA -0.7 -3.5 conserved inner membrane protein (NCBI) compare


Specific Phenotypes

For 17 genes in this experiment

For phage MOI 10 in Escherichia coli BW25113

For phage MOI 10 across organisms