Experiment set60S321 for Escherichia coli BW25113

Compare to:

TN_15CS_15C_5dbl_rep2

200 most important genes:

  gene name fitness t score description  
b0920 ycbC -4.9 -11.1 conserved inner membrane protein (NCBI) compare
b3871 bipA -3.7 -16.7 GTP-binding protein (NCBI) compare
b3162 deaD -3.4 -8.8 inducible ATP-independent RNA helicase (VIMSS) compare
b3390 aroK -3.0 -3.5 shikimate kinase I (NCBI) compare
b1187 fadR -2.9 -2.9 fatty acid metabolism regulator (NCBI) compare
b0200 gmhB -2.6 -1.8 hypothetical protein (NCBI) compare
b3183 obgE -2.6 -2.8 GTPase involved in cell partioning and DNA repair (NCBI) compare
b0888 trxB -2.5 -6.1 thioredoxin reductase, FAD/NAD(P)-binding (NCBI) compare
b0051 ksgA -2.4 -7.6 dimethyladenosine transferase (NCBI) compare
b4593 ymgI -2.3 -1.5 hypothetical protein (RefSeq) compare
b2330 yfcB -2.0 -1.9 putative adenine-specific methylase (VIMSS) compare
b3204 ptsN -2.0 -7.3 sugar-specific enzyme IIA component of PTS (NCBI) compare
b2576 srmB -1.9 -4.6 ATP-dependent RNA helicase (NCBI) compare
b3493 pitA -1.9 -10.0 phosphate transporter, low-affinity (NCBI) compare
b1863 ruvC -1.9 -3.1 Holliday junction resolvase (NCBI) compare
b4234 yjgA -1.8 -4.6 hypothetical protein (NCBI) compare
b1175 minD -1.8 -7.5 membrane ATPase of the MinC-MinD-MinE system (NCBI) compare
b1291 sapD -1.7 -2.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3261 fis -1.7 -2.5 DNA-binding protein Fis (NCBI) compare
b4375 prfC -1.7 -2.3 peptide chain release factor 3 (NCBI) compare
b3636 rpmG -1.7 -3.1 50S ribosomal protein L33 (NCBI) compare
b2935 tktA -1.7 -3.2 transketolase 1, thiamin-binding (NCBI) compare
b2501 ppk -1.7 -9.4 polyphosphate kinase (NCBI) compare
b2912 ygfA -1.7 -4.9 putative ligase (VIMSS) compare
b3613 yibP -1.6 -2.7 putative membrane protein (VIMSS) compare
b2567 rnc -1.6 -1.1 ribonuclease III (NCBI) compare
b3290 trkA -1.6 -2.3 potassium transporter peripheral membrane component (NCBI) compare
b3781 trxA -1.6 -4.1 thioredoxin 1 (VIMSS) compare
b1730 ydjO -1.5 -2.1 predicted protein (RefSeq) compare
b0149 mrcB -1.5 -12.0 penicillin-binding protein 1b (NCBI) compare
b3609 secB -1.4 -3.1 export protein SecB (NCBI) compare
b2846 yqeH -1.3 -0.8 orf, hypothetical protein (VIMSS) compare
b0759 galE -1.3 -6.2 UDP-galactose-4-epimerase (VIMSS) compare
b0738 tolR -1.3 -3.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3652 recG -1.3 -8.6 ATP-dependent DNA helicase (NCBI) compare
b3229 sspA -1.3 -4.2 stringent starvation protein A (NCBI) compare
b3198 kdsC -1.3 -5.6 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b4676 yoaK -1.3 -0.6 expressed protein (RefSeq) compare
b4202 rpsR -1.2 -1.7 30S ribosomal protein S18 (NCBI) compare
b2937 speB -1.2 -7.7 agmatinase (NCBI) compare
b1269 rluB -1.2 -3.7 23S rRNA pseudouridylate synthase (NCBI) compare
b3849 trkH -1.1 -8.1 potassium transporter (NCBI) compare
b3728 pstS -1.1 -4.2 phosphate transporter subunit (NCBI) compare
b2894 xerD -1.1 -0.7 site-specific tyrosine recombinase XerD (NCBI) compare
b0685 ybfE -1.1 -4.0 orf, hypothetical protein (VIMSS) compare
b2479 gcvR -1.1 -5.1 transcriptional regulation of gcv operon (VIMSS) compare
b0912 ihfB -1.1 -5.0 integration host factor subunit beta (NCBI) compare
b0014 dnaK -1.1 -3.2 molecular chaperone DnaK (NCBI) compare
b0049 apaH -1.0 -3.1 diadenosinetetraphosphatase (NCBI) compare
b1159 mcrA -1.0 -1.5 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b1258 yciF -1.0 -1.3 hypothetical protein (NCBI) compare
b1130 phoP -1.0 -2.5 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b3164 pnp -1.0 -2.8 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b1850 eda -1.0 -2.6 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b3863 polA -1.0 -0.9 DNA polymerase I (NCBI) compare
b2814 metZ -1.0 -1.8 tRNA-Met (NCBI) compare
b1292 sapC -1.0 -1.5 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0737 tolQ -0.9 -2.2 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2820 recB -0.9 -0.6 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b0439 lon -0.9 -4.8 DNA-binding ATP-dependent protease La (NCBI) compare
b3082 ygjM -0.9 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b0088 murD -0.9 -3.2 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b3386 rpe -0.9 -1.1 ribulose-phosphate 3-epimerase (NCBI) compare
b0890 ftsK -0.9 -2.8 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0630 lipB -0.9 -1.0 protein of lipoate biosynthesis (VIMSS) compare
b2569 lepA -0.9 -3.1 GTP-binding protein LepA (NCBI) compare
b3341 rpsG -0.9 -1.2 30S ribosomal protein S7 (NCBI) compare
b1025 ycdT -0.9 -1.7 predicted diguanylate cyclase (NCBI) compare
b1129 phoQ -0.8 -2.3 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b0082 mraW -0.8 -2.9 S-adenosyl-methyltransferase (NCBI) compare
b3868 glnG -0.8 -4.5 fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) compare
b1351 racC -0.8 -0.5 Rac prophage; predicted protein (NCBI) compare
b3149 yraO -0.8 -5.9 DnaA initiator-associating factor for replication initiation (NCBI) compare
b4146 yjeK -0.8 -2.0 predicted lysine aminomutase (NCBI) compare
b3741 gidA -0.8 -3.2 glucose-inhibited division protein A (NCBI) compare
b1658 purR -0.8 -4.2 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b1557 cspB -0.8 -1.8 Qin prophage; cold shock protein (NCBI) compare
b4685 yrbN -0.8 -1.7 expressed protein (RefSeq) compare
b2620 smpB -0.8 -1.0 SsrA-binding protein (NCBI) compare
b2318 truA -0.8 -2.4 tRNA pseudouridine synthase A (NCBI) compare
b0406 tgt -0.8 -4.5 queuine tRNA-ribosyltransferase (NCBI) compare
b1293 sapB -0.8 -0.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1160 elbA -0.7 -1.1 hypothetical protein (NCBI) compare
b3977 tyrU -0.7 -0.9 tRNA-Tyr (NCBI) compare
b3205 yhbJ -0.7 -3.6 hypothetical protein (NCBI) compare
b0767 ybhE -0.7 -2.9 6-phosphogluconolactonase (NCBI) compare
b0758 galT -0.7 -5.2 galactose-1-phosphate uridylyltransferase (NCBI) compare
b4235 pmbA -0.7 -5.8 predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) compare
b4505 insX -0.7 -1.7 predicted IS protein (RefSeq) compare
b0605 ahpC -0.7 -2.0 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b1095 fabF -0.7 -5.1 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b4647 mokA -0.7 -0.8 no description compare
b4701 sokX -0.7 -0.9 sok-related sRNA, function unknown (RefSeq) compare
b3021 ygiT -0.7 -1.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b1476 fdnI -0.7 -1.1 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b3706 trmE -0.7 -2.7 tRNA modification GTPase (NCBI) compare
b4179 vacB -0.7 -4.0 putative enzyme (VIMSS) compare
b3026 qseC -0.7 -2.9 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b0386 proC -0.7 -4.1 pyrroline-5-carboxylate reductase (NCBI) compare
b0623 cspE -0.7 -1.5 cold shock protein E (NCBI) compare
b0226 dinJ -0.7 -1.2 predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) compare
b1438 ydcQ -0.7 -3.4 predicted DNA-binding transcriptional regulator (RefSeq) compare
b1551 b1551 -0.7 -0.3 orf, hypothetical protein (VIMSS) compare
b1576 ydfD -0.7 -0.3 Qin prophage; predicted protein (NCBI) compare
b1363 trkG -0.7 -0.4 Rac prophage; potassium transporter subunit (NCBI) compare
b4208 cycA -0.7 -5.4 D-alanine/D-serine/glycine transporter (NCBI) compare
b1497 b1497 -0.7 -0.3 putative enzyme (VIMSS) compare
b1499 ydeO -0.7 -0.3 predicted DNA-binding transcriptional acfivator (NCBI) compare
b1579 intQ -0.7 -2.4 Qin prophage; predicted defective integrase (RefSeq) compare
b4414 tff -0.7 -1.5 unknown RNA (NCBI) compare
b1324 tpx -0.7 -2.3 thiol peroxidase (NCBI) compare
b0949 uup -0.7 -4.6 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b1841 yobA -0.7 -1.3 hypothetical protein (NCBI) compare
b3071 yqjI -0.7 -3.4 predicted transcriptional regulator (NCBI) compare
b1111 ycfQ -0.7 -1.9 orf, hypothetical protein (VIMSS) compare
b1182 hlyE -0.7 -0.4 hemolysin E (VIMSS) compare
b0746 valZ -0.6 -2.3 tRNA-Val (NCBI) compare
b3169 nusA -0.6 -1.5 transcription elongation factor NusA (NCBI) compare
b1165 ymgA -0.6 -0.4 hypothetical protein (NCBI) compare
b4171 miaA -0.6 -2.2 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b3775 ppiC -0.6 -3.3 peptidyl-prolyl cis-trans isomerase C (rotamase C) (NCBI) compare
b2518 ndk -0.6 -1.7 nucleoside diphosphate kinase (NCBI) compare
b1877 yecT -0.6 -1.9 orf, hypothetical protein (VIMSS) compare
b4201 priB -0.6 -1.6 primosomal replication protein N (NCBI) compare
b1259 yciG -0.6 -1.9 orf, hypothetical protein (VIMSS) compare
b0739 tolA -0.6 -2.4 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1347 ydaC -0.6 -0.3 Rac prophage; predicted protein (NCBI) compare
b1545 pinQ -0.6 -0.2 Qin prophage; predicted site-specific recombinase (NCBI) compare
b1582 ynfA -0.6 -1.7 hypothetical protein (NCBI) compare
b2938 speA -0.6 -5.0 arginine decarboxylase (NCBI) compare
b3035 tolC -0.6 -4.0 outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) compare
b1642 slyA -0.6 -1.2 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b0340 cynS -0.6 -2.1 cyanate hydratase (NCBI) compare
b1951 rcsA -0.6 -1.0 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b0101 yacG -0.6 -2.2 zinc-binding protein (NCBI) compare
b1676 pykF -0.6 -2.0 pyruvate kinase (NCBI) compare
b2168 fruK -0.6 -0.6 1-phosphofructokinase (NCBI) compare
b4570 lomR -0.6 -1.0 no description compare
b1236 galU -0.6 -2.2 glucose-1-phosphate uridylyltransferase (NCBI) compare
b4239 treC -0.6 -1.8 trehalose-6-P hydrolase (NCBI) compare
b1429 tehA -0.6 -1.1 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1332 ynaJ -0.6 -0.4 predicted inner membrane protein (NCBI) compare
b3129 sohA -0.6 -2.9 predicted regulator (NCBI) compare
b1502 ydeQ -0.6 -1.9 predicted fimbrial-like adhesin protein (NCBI) compare
b1882 cheY -0.6 -0.5 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b2007 yeeX -0.6 -1.8 conserved protein (RefSeq) compare
b4640 yoeG -0.6 -2.1 no description compare
b1257 yciE -0.6 -0.3 hypothetical protein (NCBI) compare
b1176 minC -0.6 -1.6 septum formation inhibitor (NCBI) compare
b3244 tldD -0.6 -4.6 predicted peptidase (NCBI) compare
b3163 nlpI -0.6 -2.4 hypothetical protein (NCBI) compare
b1647 ydhF -0.6 -3.2 predicted oxidoreductase (NCBI) compare
b4590 ybfK -0.6 -0.7 hypothetical protein (RefSeq) compare
b0585 fes -0.6 -3.2 enterobactin/ferric enterobactin esterase (NCBI) compare
b2051 wcaH -0.6 -0.6 GDP-mannose mannosyl hydrolase (VIMSS) compare
b3961 oxyR -0.6 -3.4 DNA-binding transcriptional dual regulator (NCBI) compare
b2614 grpE -0.5 -1.9 heat shock protein (NCBI) compare
b3621 rfaC -0.5 -2.6 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b2582 trxC -0.5 -1.4 thioredoxin 2 (NCBI) compare
b1861 ruvA -0.5 -0.8 Holliday junction DNA helicase motor protein (NCBI) compare
b2340 sixA -0.5 -1.7 phosphohistidine phosphatase (NCBI) compare
b3545 proK -0.5 -1.2 tRNA-Pro (NCBI) compare
b1167 ymgC -0.5 -0.2 hypothetical protein (NCBI) compare
b2659 b2659 -0.5 -1.3 orf, hypothetical protein (VIMSS) compare
b2948 yqgE -0.5 -1.2 orf, hypothetical protein (VIMSS) compare
b2055 wcaE -0.5 -0.3 predicted glycosyl transferase (NCBI) compare
b0450 glnK -0.5 -1.9 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b3289 rsmB -0.5 -4.0 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent (NCBI) compare
b1286 rnb -0.5 -1.3 exoribonuclease II (NCBI) compare
b4022 yjbC -0.5 -3.8 23S rRNA pseudouridine synthase (NCBI) compare
b4180 rlmB -0.5 -3.1 23S rRNA (Gm2251)-methyltransferase (NCBI) compare
b1690 ydiM -0.5 -1.5 predicted transporter (NCBI) compare
b3619 rfaD -0.5 -1.9 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b0263 afuB -0.5 -2.0 CP4-6 prophage; predicted ferric trasnporter subunit (RefSeq) compare
b2784 relA -0.5 -3.4 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b0015 dnaJ -0.5 -3.3 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b2066 udk -0.5 -3.5 uridine/cytidine kinase (VIMSS) compare
b3120 yhaB -0.5 -1.2 orf, hypothetical protein (VIMSS) compare
b1323 tyrR -0.5 -2.7 DNA-binding transcriptional dual regulator, tyrosine-binding (NCBI) compare
b4497 yeeL -0.5 -0.8 no description compare
b4203 rplI -0.5 -3.1 50S ribosomal protein L9 (NCBI) compare
b1527 yneK -0.5 -1.8 hypothetical protein (NCBI) compare
b2699 recA -0.5 -0.5 recombinase A (NCBI) compare
b2198 ccmD -0.5 -1.3 cytochrome c biogenesis protein (NCBI) compare
b1001 yccE -0.5 -0.2 hypothetical protein (NCBI) compare
b0740 tolB -0.5 -2.3 translocation protein TolB precursor (NCBI) compare
b2688 gshA -0.5 -3.1 glutamate--cysteine ligase (NCBI) compare
b0908 aroA -0.5 -3.2 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b3389 aroB -0.5 -3.6 3-dehydroquinate synthase (NCBI) compare
b1105 ycfM -0.5 -2.7 predicted outer membrane lipoprotein (NCBI) compare
b1533 ydeD -0.5 -1.5 orf, hypothetical protein (VIMSS) compare
b4511 ybdZ -0.5 -2.0 hypothetical protein (NCBI) compare
b0237 pepD -0.5 -3.2 aminoacyl-histidine dipeptidase (peptidase D) (NCBI) compare
b1855 lpxM -0.5 -1.9 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b0683 fur -0.5 -0.5 ferric uptake regulator (NCBI) compare
b0976 hyaE -0.5 -2.3 protein involved in processing of HyaA and HyaB proteins (NCBI) compare
b1920 fliY -0.5 -0.9 cystine transporter subunit (NCBI) compare
b0741 pal -0.5 -2.5 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b1950 fliR -0.5 -2.0 flagellar biosynthesis protein R (NCBI) compare
b1536 ydeI -0.5 -0.6 hypothetical protein (NCBI) compare


Specific Phenotypes

None in this experiment