Experiment set5IT076 for Agrobacterium fabrum C58

Compare to:

R2A with Trimethoprim 2.5 mM

200 most important genes:

  gene name fitness t score description  
Atu1688 -2.9 -4.4 indole-3-glycerol-phosphate synthase compare
Atu0434 -2.7 -3.0 2'-deoxycytidine 5'-triphosphate deaminase compare
Atu1687 -2.6 -6.2 anthranilate phosphoribosyltransferase compare
Atu1354 -2.6 -2.0 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase compare
Atu3469 -2.4 -2.6 phosphoglyceromutase compare
Atu2289 -2.3 -13.0 anthranilate synthase component I and II compare
Atu0723 -2.2 -3.0 FAD dependent oxidoreductase compare
Atu1446 -1.8 -2.3 two component response regulator compare
Atu1307 -1.8 -7.1 dihydroorotase compare
Atu0399 -1.8 -5.8 dihydroorotase compare
Atu0017 -1.7 -2.2 N-(5-phosphoribosyl) anthranilate isomerase compare
Atu2684 -1.7 -1.8 hypothetical protein compare
Atu0039 -1.7 -2.9 imidazoleglycerol-phosphate synthase cyclase compare
Atu0486 -1.6 -5.4 dihydroorotate dehydrogenase compare
Atu0346 -1.5 -3.3 uridylyltransferase/uridylyl-removing enzyme UTase compare
Atu4317 -1.4 -3.8 TetR family transcriptional regulator compare
Atu1028 -1.4 -3.3 hypothetical protein compare
Atu1308 -1.4 -4.8 aspartate carbamoyl transferase catalytic subunit compare
Atu6098 -1.3 -0.9 transcriptional regulator, HTH family compare
Atu2728 -1.3 -3.9 beta (1-->2) glucan export ATP-binding protein compare
Atu0103 -1.2 -7.8 penicillin-binding protein compare
Atu1359 -1.2 -1.4 dnaK deletion suppressor protein compare
Atu1686 -1.2 -6.1 peptidyl-prolyl cis-trans isomerse D compare
Atu0876 -1.2 -1.5 superoxide dismutase compare
Atu2710 -1.1 -6.1 hypothetical protein compare
Atu0298 -1.1 -4.7 orotidine 5 compare
Atu1891 -1.1 -3.8 cobalamin biosynthesis protein compare
Atu2073 -1.1 -3.3 membrane protein compare
Atu1542 -1.0 -4.5 Bifunctional adenosylcobalamin biosynthesis protein cobP compare
Atu4897 -1.0 -1.9 hypothetical protein compare
Atu0041 -1.0 -1.7 glutamine amidotransferase compare
Atu0400 -1.0 -3.2 orotate phosphoribosyltransferase compare
Atu4075 -1.0 -5.1 glycogen synthase compare
Atu2793 -1.0 -4.2 cobyrinic acid a,c-diamide synthase compare
Atu2796 -0.9 -3.9 precorrin-4 C11-methyltransferase compare
Atu0142 -0.9 -1.3 cytochrome o ubiquinol oxidase subunit II compare
Atu0331 -0.9 -3.2 sigma-54 modulation protein compare
Atu0031 -0.8 -1.3 PTS system, IIA component compare
Atu8191 -0.8 -2.0 hypothetical protein compare
Atu1141 -0.8 -3.6 Phosphoribosylglycinamide synthetase compare
Atu2432 -0.8 -1.6 hypothetical protein compare
Atu4217 -0.8 -1.8 TetR family transcriptional regulator compare
Atu3707 -0.8 -2.5 phosphoserine aminotransferase compare
Atu1075 -0.8 -3.5 amidophosphoribosyltransferase compare
Atu2439 -0.8 -1.1 hypothetical protein compare
Atu0029 -0.8 -3.1 S-adenosylhomocysteine hydrolase compare
Atu3012 -0.8 -0.9 hypothetical protein compare
Atu0647 -0.8 -3.9 phosphoribosylamine--glycine ligase compare
Atu0795 -0.8 -2.3 hypothetical protein compare
Atu3730 -0.8 -1.1 hypothetical protein compare
Atu5107 -0.7 -2.7 hypothetical protein compare
Atu0361 -0.7 -1.9 transcriptional regulator compare
Atu2801 -0.7 -3.3 precorrin-2 C20 methyltransferase compare
Atu2798 -0.7 -3.3 precorrin-6y methyltransferase compare
Atu3727 -0.7 -2.5 hypothetical protein compare
Atu0188 -0.7 -1.7 ABC transporter, membrane spanning protein (peptide) compare
Atu3750 -0.7 -2.3 thiamine-phosphate pyrophosphorylase compare
Atu2797 -0.7 -2.8 cobalamin biosynthesis protein compare
Atu2650 -0.7 -5.0 glycerol-3-phosphate dehydrogenase compare
Atu6189 -0.7 -0.9 protein secretion chaperone compare
Atu2036 -0.7 -5.2 acetolactate synthase III, large subunit compare
Atu0463 -0.7 -2.4 hypothetical protein compare
Atu2640 -0.7 -3.3 hypothetical protein compare
Atu0184 -0.7 -1.2 glucokinase compare
Atu0479 -0.7 -4.1 ABC transporter, substrate binding protein (amino acid) compare
Atu2554 -0.7 -1.4 lysyl-tRNA synthetase compare
Atu2802 -0.7 -3.7 precorrin-8X methylmutase compare
Atu0598 -0.7 -3.4 phosphogluconate dehydratase compare
Atu3755 -0.7 -2.7 phosphoribosylaminoimidazole carboxylase ATPase subunit compare
Atu0972 -0.7 -3.3 lipA protein compare
Atu2787 -0.7 -0.9 hypothetical protein compare
Atu2657 -0.7 -2.1 hypothetical protein compare
Atu1286 -0.6 -2.3 hypothetical protein compare
Atu4148 -0.6 -2.5 UDP-glucuronic acid epimerase compare
Atu1182 -0.6 -1.7 hypothetical protein compare
Atu1077 -0.6 -2.3 DNA repair protein compare
Atu6045 -0.6 -1.2 replication protein C compare
Atu1588 -0.6 -3.6 homoserine dehydrogenase compare
Atu3593 -0.6 -3.8 hypothetical protein compare
Atu4686 -0.6 -1.6 hypothetical protein compare
Atu4342 -0.6 -2.1 hypothetical protein compare
Atu3324 -0.6 -3.2 hypothetical protein compare
Atu0025 -0.6 -1.2 hypothetical protein compare
Atu1140 -0.6 -3.0 phosphoribosyalaminoimidazole-succinocarboxamide synthase compare
Atu5173 -0.6 -1.7 dehydrogenase compare
Atu1030 -0.6 -1.0 GTP pyrophosphohydrolase/synthetase, RelA/SpoT family compare
Atu2804 -0.6 -4.4 cobaltochelatase subunit compare
Atu2832 -0.6 -1.9 tRNA modification GTPase compare
Atu8138 -0.6 -1.2 hypothetical protein compare
Atu1836 -0.6 -1.5 hypothetical protein compare
Atu3688 -0.6 -2.3 iron(III ABC transporter permease dicitrate ABC transporter permease compare
Atu5045 -0.6 -1.0 hypothetical protein compare
Atu0544 -0.6 -1.7 hypothetical protein compare
Atu4451 -0.6 -4.0 mannitol 2-dehydrogenase compare
Atu0322 -0.6 -2.4 enoyl CoA hydratase compare
Atu2040 -0.6 -2.0 phosphoserine phosphatase compare
Atu2809 -0.6 -3.1 cobalamin biosynthesis protein compare
Atu4773 -0.6 -1.3 two component response regulator compare
Atu4890 -0.6 -1.3 IS426 transposase compare
Atu3014 -0.6 -1.2 hypothetical protein compare
Atu1844 -0.6 -1.1 Phosphoribosylformylglycinamidine synthetase compare
Atu3634 -0.5 -2.5 penicillin-binding protein dacf precursor compare
Atu3001 -0.5 -1.3 hypothetical protein compare
Atu2807 -0.5 -3.1 cob(I)alamin adenosyltransferase compare
Atu0185 -0.5 -2.7 methylglyoxal synthase compare
Atu8143 -0.5 -2.3 hypothetical protein compare
Atu0846 -0.5 -1.9 transcriptional regulator, MarR family compare
Atu3018 -0.5 -2.0 hypothetical protein compare
Atu4879 -0.5 -3.3 hypothetical protein compare
Atu4093 -0.5 -1.8 hypothetical protein compare
Atu2193 -0.5 -0.7 hypothetical protein compare
Atu1573 -0.5 -1.1 hypothetical protein compare
Atu0401 -0.5 -2.3 fructokinase compare
Atu3478 -0.5 -2.8 3-methylcrotonoyl-CoA carboxylase beta subunit compare
Atu1252 -0.5 -1.6 hypothetical protein compare
Atu2464 -0.5 -1.7 formyltetrahydrofolate deformylase compare
Atu1503 -0.5 -0.7 hypothetical protein compare
Atu5501 -0.5 -1.3 hypothetical protein compare
Atu1902 -0.5 -2.1 transketolase compare
Atu2808 -0.5 -3.2 cobyric acid synthase compare
Atu2805 -0.5 -2.6 cobalamin synthesis protein compare
Atu5010 -0.5 -1.6 hypothetical protein compare
Atu0153 -0.5 -1.9 transcriptional regulator, Fur family compare
Atu0062 -0.5 -2.7 transcriptional regulator, ROK family compare
Atu3754 -0.5 -1.5 phosphoribosylaminoimidazole carboxylase catalytic subunit compare
Atu2207 -0.5 -2.3 two component sensor kinase compare
Atu0726 -0.5 -2.6 ring hydroxylating dioxygenase, alpha-subunit compare
Atu2799 -0.5 -1.5 precorrin-6x reductase compare
Atu2766 -0.5 -4.3 NAD-glutamate dehydrogenase compare
Atu5196 -0.5 -2.3 hypothetical protein compare
Atu0971 -0.5 -1.7 two component sensor kinase compare
Atu5106 -0.5 -1.6 DNA binding protein compare
Atu2479 -0.5 -0.9 tRNA-Gly compare
Atu0101 -0.5 -1.1 cytochrome c compare
Atu4618 -0.5 -3.6 dTDP-rhamnose-3,5-epimerase compare
Atu2800 -0.5 -1.1 precorrin-3B C17-methyltransferase compare
Atu0421 -0.5 -0.8 ABC transporter, membrane spanning protein compare
Atu5057 -0.5 -1.1 hypothetical protein compare
Atu2068 -0.5 -2.1 hypothetical protein compare
Atu8056 -0.5 -0.7 hypothetical protein compare
Atu1056 -0.5 -2.1 hypothetical protein compare
Atu2633 -0.5 -1.3 RhtB family transporter compare
Atu2795 -0.5 -2.5 cobalamin biosynthetic protein compare
Atu1589 -0.5 -2.3 aminotransferase, class I compare
Atu3706 -0.5 -2.4 D-3-phosphoglycerate dehydrogenase compare
Atu3485 -0.5 -3.0 short chain dehydrogenase compare
Atu0594 -0.5 -3.0 alpha-glucosidase compare
Atu4892 -0.4 -3.6 hypothetical protein compare
Atu4418 -0.4 -2.1 glutaryl-CoA dehydrogenase compare
Atu2083 -0.4 -1.0 DNA repair protein RecN compare
Atu4469 -0.4 -1.6 iron ABC transporter permease compare
Atu1770 -0.4 -3.0 glutamine synthetase compare
Atu1774 -0.4 -2.2 ABC transporter, substrate binding protein (peptide) compare
Atu1021 -0.4 -0.9 outer membrane protein compare
Atu1066 -0.4 -2.0 hypothetical protein compare
Atu4346 -0.4 -2.4 hypothetical protein compare
Atu1634 -0.4 -1.2 hypothetical protein compare
Atu5502 -0.4 -2.2 hypothetical protein compare
Atu4290 -0.4 -1.2 hypothetical protein compare
Atu0295 -0.4 -1.8 hypothetical protein compare
Atu1163 -0.4 -0.9 exopolysaccharide II synthesis transcriptional activator ExpG compare
Atu1191 -0.4 -1.0 hypothetical protein compare
Atu0977 -0.4 -2.4 serine protease DO-like protease compare
Atu3466 -0.4 -1.8 ArsR family transcriptional regulator compare
Atu2772 -0.4 -2.0 Invasion protein A compare
Atu2768 -0.4 -2.4 hypothetical protein compare
Atu0135 -0.4 -1.8 uracil phosphoribosyltransferase compare
Atu0044 -0.4 -2.2 heat shock protein hslV compare
Atu3515 -0.4 -2.2 hypothetical protein compare
Atu1559 -0.4 -1.7 hypothetical protein compare
Atu1685 -0.4 -0.5 hypothetical protein compare
Atu2713 -0.4 -3.0 ABC transporter, membrane spanning protein (thiamine) compare
Atu0280 -0.4 -1.2 hypothetical protein compare
Atu0727 -0.4 -2.5 ferredoxin I compare
Atu4857 -0.4 -2.0 mobilization protein C compare
Atu2683 -0.4 -0.9 hypothetical protein compare
Atu6195 -0.4 -1.8 conserved hypothetical protein compare
Atu3121 -0.4 -0.7 cold shock protein compare
Atu0190 -0.4 -2.2 ABC transporter, nucleotide binding/ATPase protein (peptide) compare
Atu3006 -0.4 -1.9 hypothetical protein compare
Atu1355 -0.4 -2.4 hypothetical protein compare
Atu3872 -0.4 -2.6 hypothetical protein compare
Atu1647 -0.4 -2.8 ABC transporter, membrane spanning protein compare
Atu2742 -0.4 -2.0 hypothetical protein compare
Atu1333 -0.4 -0.7 outer membrane protein compare
Atu8032 -0.4 -1.2 hypothetical protein compare
Atu0565 -0.4 -1.9 hypothetical protein compare
Atu0606 -0.4 -1.0 hypothetical protein compare
Atu4199 -0.4 -2.9 TetR family transcriptional regulator compare
Atu1203 -0.4 -1.4 hypothetical protein compare
Atu4641 -0.4 -1.1 LysR family transcriptional regulator compare
Atu1850 -0.4 -1.1 phosphoribosylformylglycinamidine synthetase II compare
Atu1620 -0.4 -2.6 triosephosphate isomerase compare
Atu0036 -0.4 -1.3 hypothetical protein compare
Atu4187 -0.4 -0.7 tRNA-Met compare
Atu0043 -0.4 -0.8 imidazoleglycerol-phosphate dehydratase compare
Atu8096 -0.4 -0.9 hypothetical protein compare
Atu1320 -0.4 -1.8 acetyltransferase compare
Atu6155 -0.4 -1.9 conserved hypothetical protein compare
Atu5440 -0.4 -1.8 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Agrobacterium fabrum C58 in stress experiments

For stress Trimethoprim across organisms