| | gene | name | fitness | t score | description | |
|---|
| b3035 | tolC | -5.0 | -12.1 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) | compare |
| b0741 | pal | -4.3 | -8.7 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b1293 | sapB | -4.0 | -3.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1292 | sapC | -3.8 | -5.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0740 | tolB | -3.8 | -9.1 | translocation protein TolB precursor (NCBI) | compare |
| b3613 | yibP | -3.7 | -10.2 | putative membrane protein (VIMSS) | compare |
| b2830 | nudH | -3.7 | -2.6 | dinucleoside polyphosphate hydrolase (NCBI) | compare |
| b0737 | tolQ | -3.7 | -6.1 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b3619 | rfaD | -3.4 | -8.9 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b2912 | ygfA | -3.3 | -7.1 | putative ligase (VIMSS) | compare |
| b0437 | clpP | -3.3 | -10.8 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b2188 | yejM | -3.3 | -14.4 | predicted hydrolase, inner membrane (NCBI) | compare |
| b0738 | tolR | -3.3 | -5.4 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0726 | sucA | -3.2 | -6.7 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b1863 | ruvC | -3.2 | -4.1 | Holliday junction resolvase (NCBI) | compare |
| b2168 | fruK | -3.1 | -2.1 | 1-phosphofructokinase (NCBI) | compare |
| b1192 | ldcA | -3.1 | -8.6 | L,D-carboxypeptidase A (NCBI) | compare |
| b1290 | sapF | -3.1 | -3.1 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0439 | lon | -3.0 | -8.7 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b3398 | yrfF | -3.0 | -5.6 | predicted inner membrane protein (NCBI) | compare |
| b0739 | tolA | -3.0 | -6.4 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b1861 | ruvA | -2.9 | -2.6 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b3375 | yhfR | -2.9 | -11.0 | putative transcriptional regulator (VIMSS) | compare |
| b0890 | ftsK | -2.9 | -6.1 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b3792 | wzxE | -2.8 | -10.5 | O-antigen translocase (NCBI) | compare |
| b3839 | tatC | -2.7 | -10.6 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0114 | aceE | -2.7 | -1.9 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b1291 | sapD | -2.7 | -3.0 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0149 | mrcB | -2.7 | -17.5 | penicillin-binding protein 1b (NCBI) | compare |
| b1860 | ruvB | -2.6 | -1.7 | Holliday junction DNA helicase B (NCBI) | compare |
| b2699 | recA | -2.6 | -1.8 | recombinase A (NCBI) | compare |
| b0019 | nhaA | -2.5 | -10.1 | pH-dependent sodium/proton antiporter (NCBI) | compare |
| b3870 | glnA | -2.5 | -4.1 | glutamine synthetase (NCBI) | compare |
| b0053 | surA | -2.4 | -8.2 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b4647 | mokA | -2.4 | -1.4 | no description | compare |
| b0688 | pgm | -2.4 | -5.2 | phosphoglucomutase (NCBI) | compare |
| b0200 | gmhB | -2.4 | -2.6 | hypothetical protein (NCBI) | compare |
| b3620 | rfaF | -2.4 | -7.9 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b2620 | smpB | -2.3 | -2.0 | SsrA-binding protein (NCBI) | compare |
| b4239 | treC | -2.3 | -4.1 | trehalose-6-P hydrolase (NCBI) | compare |
| b2498 | upp | -2.2 | -3.9 | uracil phosphoribosyltransferase (VIMSS) | compare |
| b3621 | rfaC | -2.2 | -8.7 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b2894 | xerD | -2.2 | -1.8 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b2846 | yqeH | -2.2 | -1.1 | orf, hypothetical protein (VIMSS) | compare |
| b0912 | ihfB | -2.2 | -9.1 | integration host factor subunit beta (NCBI) | compare |
| b3150 | yraP | -2.1 | -11.9 | hypothetical protein (NCBI) | compare |
| b3386 | rpe | -2.1 | -1.4 | ribulose-phosphate 3-epimerase (NCBI) | compare |
| b3052 | rfaE | -2.1 | -6.9 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b2518 | ndk | -2.1 | -4.2 | nucleoside diphosphate kinase (NCBI) | compare |
| b3236 | mdh | -2.0 | -8.0 | malate dehydrogenase (NCBI) | compare |
| b4146 | yjeK | -2.0 | -5.2 | predicted lysine aminomutase (NCBI) | compare |
| b3075 | ebgR | -2.0 | -6.4 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3026 | qseC | -2.0 | -6.7 | sensory histidine kinase in two-component regulatory system with QseB (NCBI) | compare |
| b0438 | clpX | -2.0 | -7.0 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b0720 | gltA | -2.0 | -8.5 | citrate synthase (NCBI) | compare |
| b3863 | polA | -1.9 | -2.0 | DNA polymerase I (NCBI) | compare |
| b3405 | ompR | -1.9 | -6.0 | osmolarity response regulator (NCBI) | compare |
| b4172 | hfq | -1.9 | -1.7 | RNA-binding protein Hfq (NCBI) | compare |
| b2569 | lepA | -1.8 | -5.8 | GTP-binding protein LepA (NCBI) | compare |
| b1236 | galU | -1.8 | -5.1 | glucose-1-phosphate uridylyltransferase (NCBI) | compare |
| b1176 | minC | -1.8 | -3.8 | septum formation inhibitor (NCBI) | compare |
| b3811 | xerC | -1.8 | -1.7 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b3237 | argR | -1.8 | -5.9 | arginine repressor (NCBI) | compare |
| b3290 | trkA | -1.8 | -2.7 | potassium transporter peripheral membrane component (NCBI) | compare |
| b1258 | yciF | -1.8 | -1.7 | hypothetical protein (NCBI) | compare |
| b0767 | ybhE | -1.7 | -5.3 | 6-phosphogluconolactonase (NCBI) | compare |
| b2512 | yfgL | -1.6 | -6.1 | protein assembly complex, lipoprotein component (NCBI) | compare |
| b1709 | btuD | -1.6 | -1.6 | vitamin B12-transporter ATPase (NCBI) | compare |
| b1748 | astC | -1.6 | -8.6 | succinylornithine transaminase, PLP-dependent (NCBI) | compare |
| b3204 | ptsN | -1.6 | -5.1 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b4593 | ymgI | -1.6 | -1.0 | hypothetical protein (RefSeq) | compare |
| b4155 | yjeA | -1.6 | -1.1 | putative lysyl-tRNA synthetase (VIMSS) | compare |
| b2741 | rpoS | -1.6 | -7.9 | RNA polymerase sigma factor (NCBI) | compare |
| b2567 | rnc | -1.6 | -1.0 | ribonuclease III (NCBI) | compare |
| b3741 | gidA | -1.6 | -7.6 | glucose-inhibited division protein A (NCBI) | compare |
| b2952 | yggT | -1.5 | -5.0 | predicted inner membrane protein (NCBI) | compare |
| b3791 | rffA | -1.5 | -8.0 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b3962 | udhA | -1.5 | -6.0 | putative oxidoreductase (VIMSS) | compare |
| b4175 | hflC | -1.5 | -7.6 | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | compare |
| b1936 | intG | -1.5 | -1.5 | predicted defective phage integrase (pseudogene) (RefSeq) | compare |
| b3082 | ygjM | -1.4 | -2.6 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3199 | yrbK | -1.4 | -2.8 | hypothetical protein (NCBI) | compare |
| b4214 | cysQ | -1.4 | -9.8 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b0080 | fruR | -1.4 | -5.9 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2820 | recB | -1.4 | -0.9 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b4174 | hflK | -1.4 | -9.3 | modulator for HflB protease specific for phage lambda cII repressor (NCBI) | compare |
| b2175 | spr | -1.4 | -4.0 | predicted peptidase, outer membrane lipoprotein (NCBI) | compare |
| b0222 | lpcA | -1.3 | -2.5 | phosphoheptose isomerase (NCBI) | compare |
| b4676 | yoaK | -1.3 | -0.5 | expressed protein (RefSeq) | compare |
| b0888 | trxB | -1.3 | -3.3 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b3609 | secB | -1.3 | -2.3 | export protein SecB (NCBI) | compare |
| b3706 | trmE | -1.3 | -5.0 | tRNA modification GTPase (NCBI) | compare |
| b1830 | prc | -1.3 | -6.1 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b4481 | rffT | -1.3 | -5.2 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b3652 | recG | -1.3 | -8.0 | ATP-dependent DNA helicase (NCBI) | compare |
| b1105 | ycfM | -1.3 | -5.5 | predicted outer membrane lipoprotein (NCBI) | compare |
| b3194 | yrbE | -1.3 | -8.1 | predicted toluene transporter subunit: membrane component of ABC superfamily (NCBI) | compare |
| b2064 | asmA | -1.3 | -7.0 | predicted assembly protein (NCBI) | compare |
| b4203 | rplI | -1.3 | -5.0 | 50S ribosomal protein L9 (NCBI) | compare |
| b2058 | wcaB | -1.3 | -1.7 | predicted acyl transferase (NCBI) | compare |
| b4375 | prfC | -1.3 | -5.8 | peptide chain release factor 3 (NCBI) | compare |
| b2808 | gcvA | -1.3 | -3.8 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2934 | cmtB | -1.2 | -1.0 | predicted mannitol-specific enzyme IIA component of PTS (NCBI) | compare |
| b3977 | tyrU | -1.2 | -1.2 | tRNA-Tyr (NCBI) | compare |
| b3426 | glpD | -1.2 | -3.8 | sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) | compare |
| b2531 | iscR | -1.2 | -1.7 | DNA-binding transcriptional repressor (NCBI) | compare |
| b0949 | uup | -1.2 | -6.6 | fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) | compare |
| b2939 | yqgB | -1.2 | -1.7 | predicted protein (RefSeq) | compare |
| b3404 | envZ | -1.2 | -7.9 | osmolarity sensor protein (NCBI) | compare |
| b1865 | nudB | -1.2 | -1.6 | dATP pyrophosphohydrolase (NCBI) | compare |
| b1175 | minD | -1.2 | -5.1 | membrane ATPase of the MinC-MinD-MinE system (NCBI) | compare |
| b3838 | tatB | -1.2 | -5.3 | sec-independent translocase (NCBI) | compare |
| b3912 | cpxR | -1.2 | -7.0 | DNA-binding response regulator in two-component regulatory system with CpxA (NCBI) | compare |
| b1747 | astA | -1.2 | -7.4 | arginine succinyltransferase (NCBI) | compare |
| b3623 | rfaK | -1.1 | -2.0 | lipopolysaccharide core biosynthesis (NCBI) | compare |
| b3842 | rfaH | -1.1 | -4.3 | transcriptional activator RfaH (NCBI) | compare |
| b0082 | mraW | -1.1 | -3.4 | S-adenosyl-methyltransferase (NCBI) | compare |
| b3169 | nusA | -1.1 | -2.5 | transcription elongation factor NusA (NCBI) | compare |
| b0730 | mngR | -1.1 | -1.8 | DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) | compare |
| b3500 | gor | -1.1 | -2.1 | glutathione reductase (NCBI) | compare |
| b0406 | tgt | -1.1 | -4.8 | queuine tRNA-ribosyltransferase (NCBI) | compare |
| b3781 | trxA | -1.1 | -3.5 | thioredoxin 1 (VIMSS) | compare |
| b0407 | yajC | -1.1 | -2.2 | preprotein translocase subunit YajC (NCBI) | compare |
| b0161 | degP | -1.1 | -5.6 | serine endoprotease (protease Do), membrane-associated (NCBI) | compare |
| b3725 | pstB | -1.1 | -0.7 | phosphate transporter subunit (NCBI) | compare |
| b3438 | gntR | -1.1 | -4.9 | DNA-binding transcriptional repressor (NCBI) | compare |
| b0928 | aspC | -1.1 | -6.6 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b1745 | astB | -1.1 | -4.3 | succinylarginine dihydrolase (NCBI) | compare |
| b1084 | rne | -1.1 | -4.5 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b3465 | yhhF | -1.1 | -4.6 | predicted methyltransferase (NCBI) | compare |
| b2935 | tktA | -1.1 | -2.5 | transketolase 1, thiamin-binding (NCBI) | compare |
| b2313 | cvpA | -1.1 | -3.1 | membrane protein required for colicin V production (NCBI) | compare |
| b3979 | thrT | -1.1 | -0.4 | tRNA-Thr (NCBI) | compare |
| b2762 | cysH | -1.1 | -6.2 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b1677 | lpp | -1.0 | -1.7 | murein lipoprotein (NCBI) | compare |
| b0819 | ybiS | -1.0 | -6.5 | hypothetical protein (NCBI) | compare |
| b3163 | nlpI | -1.0 | -4.0 | hypothetical protein (NCBI) | compare |
| b4139 | aspA | -1.0 | -7.0 | aspartate ammonia-lyase (aspartase) (VIMSS) | compare |
| b1746 | astD | -1.0 | -5.7 | succinylglutamic semialdehyde dehydrogenase (NCBI) | compare |
| b3198 | kdsC | -1.0 | -3.4 | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) | compare |
| b2501 | ppk | -1.0 | -4.8 | polyphosphate kinase (NCBI) | compare |
| b3790 | rffC | -1.0 | -4.4 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b0722 | sdhD | -1.0 | -3.2 | succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) | compare |
| b1804 | rnd | -1.0 | -4.4 | ribonuclease D (NCBI) | compare |
| b2288 | nuoA | -1.0 | -2.8 | NADH dehydrogenase I chain A (VIMSS) | compare |
| b0585 | fes | -1.0 | -4.6 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b1545 | pinQ | -1.0 | -0.3 | Qin prophage; predicted site-specific recombinase (NCBI) | compare |
| b2189 | proL | -1.0 | -1.9 | tRNA-Pro (NCBI) | compare |
| b2447 | yffP | -1.0 | -3.1 | CPZ-55 prophage; predicted protein (NCBI) | compare |
| b1129 | phoQ | -1.0 | -1.8 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b0142 | folK | -1.0 | -0.5 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b4178 | yjeB | -1.0 | -4.9 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b0015 | dnaJ | -1.0 | -6.6 | chaperone Hsp40, co-chaperone with DnaK (NCBI) | compare |
| b0441 | ppiD | -1.0 | -6.6 | peptidyl-prolyl cis-trans isomerase (rotamase D) (NCBI) | compare |
| b3250 | mreC | -0.9 | -1.0 | cell wall structural complex MreBCD transmembrane component MreC (NCBI) | compare |
| b2479 | gcvR | -0.9 | -4.0 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b3631 | rfaG | -0.9 | -7.7 | glucosyltransferase I (NCBI) | compare |
| b1482 | osmC | -0.9 | -2.3 | osmotically inducible, stress-inducible membrane protein (NCBI) | compare |
| b1104 | ycfL | -0.9 | -2.1 | hypothetical protein (NCBI) | compare |
| b3933 | ftsN | -0.9 | -3.9 | essential cell division protein (NCBI) | compare |
| b1744 | astE | -0.9 | -3.9 | succinylglutamate desuccinylase (NCBI) | compare |
| b2822 | recC | -0.9 | -4.5 | exonuclease V (RecBCD complex), gamma chain (NCBI) | compare |
| b1712 | ihfA | -0.9 | -2.0 | integration host factor subunit alpha (NCBI) | compare |
| b3120 | yhaB | -0.9 | -1.8 | orf, hypothetical protein (VIMSS) | compare |
| b3027 | ygiZ | -0.9 | -0.5 | conserved inner membrane protein (NCBI) | compare |
| b1696 | ydiP | -0.9 | -2.1 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3727 | pstC | -0.9 | -6.5 | phosphate transporter subunit (NCBI) | compare |
| b1085 | b1085 | -0.9 | -2.1 | orf, hypothetical protein (VIMSS) | compare |
| b1961 | dcm | -0.9 | -1.5 | DNA cytosine methylase (NCBI) | compare |
| b2029 | gnd | -0.9 | -5.2 | 6-phosphogluconate dehydrogenase (NCBI) | compare |
| b3849 | trkH | -0.9 | -5.5 | potassium transporter (NCBI) | compare |
| b0926 | ycbK | -0.9 | -3.1 | hypothetical protein (NCBI) | compare |
| b1758 | b1758 | -0.9 | -1.1 | putative cytochrome oxidase (VIMSS) | compare |
| b3630 | rfaP | -0.8 | -6.0 | kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) | compare |
| b1730 | ydjO | -0.8 | -0.9 | predicted protein (RefSeq) | compare |
| b2297 | pta | -0.8 | -1.1 | phosphate acetyltransferase (NCBI) | compare |
| b3935 | priA | -0.8 | -1.2 | primosome assembly protein PriA (NCBI) | compare |
| b0677 | nagA | -0.8 | -4.0 | N-acetylglucosamine-6-phosphate deacetylase (NCBI) | compare |
| b3466 | yhhL | -0.8 | -3.6 | conserved inner membrane protein (NCBI) | compare |
| b0908 | aroA | -0.8 | -5.0 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b2281 | nuoI | -0.8 | -2.9 | NADH dehydrogenase subunit I (NCBI) | compare |
| b0721 | sdhC | -0.8 | -3.9 | succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) | compare |
| b0685 | ybfE | -0.8 | -2.2 | orf, hypothetical protein (VIMSS) | compare |
| b2340 | sixA | -0.8 | -2.6 | phosphohistidine phosphatase (NCBI) | compare |
| b2504 | yfgG | -0.8 | -1.4 | Negative regulator of nickel and cobalt uptake (YfgG) (from data) | compare |
| b0724 | sdhB | -0.8 | -4.2 | succinate dehydrogenase, FeS subunit (NCBI) | compare |
| b0564 | appY | -0.8 | -0.8 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b0386 | proC | -0.8 | -3.9 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2796 | sdaC | -0.8 | -6.4 | predicted serine transporter (NCBI) | compare |
| b4180 | rlmB | -0.8 | -4.3 | 23S rRNA (Gm2251)-methyltransferase (NCBI) | compare |
| b4179 | vacB | -0.8 | -3.8 | putative enzyme (VIMSS) | compare |
| b2513 | yfgM | -0.8 | -2.8 | hypothetical protein (NCBI) | compare |
| b2258 | b2258 | -0.8 | -1.0 | putative transport/receptor protein (VIMSS) | compare |
| b2330 | yfcB | -0.8 | -1.2 | putative adenine-specific methylase (VIMSS) | compare |
| b2215 | ompC | -0.8 | -4.8 | outer membrane porin protein C (NCBI) | compare |
| b2051 | wcaH | -0.7 | -1.6 | GDP-mannose mannosyl hydrolase (VIMSS) | compare |
| b3617 | kbl | -0.7 | -4.1 | 2-amino-3-ketobutyrate coenzyme A ligase (NCBI) | compare |
| b1427 | rimL | -0.7 | -2.9 | ribosomal-protein-L7/L12-serine acetyltransferase (NCBI) | compare |
| b3624 | rfaZ | -0.7 | -1.4 | lipopolysaccharide core biosynthesis protein (NCBI) | compare |
| b3193 | yrbD | -0.7 | -4.7 | predicted ABC-type organic solvent transporter (NCBI) | compare |