| | gene | name | fitness | t score | description | |
|---|
| b0611 | rna | -9.6 | -5.1 | ribonuclease I (NCBI) | compare |
| b2945 | endA | -8.2 | -8.8 | DNA-specific endonuclease I (NCBI) | compare |
| b2784 | relA | -8.0 | -5.5 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b1830 | prc | -6.1 | -4.2 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b3163 | nlpI | -5.6 | -6.8 | hypothetical protein (NCBI) | compare |
| b2819 | recD | -5.3 | -9.2 | exonuclease V (RecBCD complex), alpha chain (NCBI) | compare |
| b0053 | surA | -5.2 | -6.2 | peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) | compare |
| b3790 | rffC | -5.0 | -7.4 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b3839 | tatC | -4.7 | -7.8 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0222 | lpcA | -4.7 | -2.5 | phosphoheptose isomerase (NCBI) | compare |
| b3341 | rpsG | -4.6 | -1.4 | 30S ribosomal protein S7 (NCBI) | compare |
| b3794 | rffM | -4.5 | -11.1 | putative UDP-N-acetyl-D-mannosaminuronic acid transferase (NCBI) | compare |
| b3791 | rffA | -4.5 | -13.4 | TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) | compare |
| b3784 | rfe | -4.1 | -15.8 | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase (NCBI) | compare |
| b1613 | manA | -4.1 | -3.4 | mannose-6-phosphate isomerase (VIMSS) | compare |
| b0439 | lon | -4.1 | -4.9 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b3621 | rfaC | -4.1 | -2.8 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b3786 | rffE | -4.1 | -16.4 | UDP-N-acetyl glucosamine-2-epimerase (NCBI) | compare |
| b3620 | rfaF | -4.0 | -4.8 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b1291 | sapD | -4.0 | -2.4 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3787 | rffD | -3.8 | -12.9 | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase (NCBI) | compare |
| b0903 | pflB | -3.7 | -16.4 | pyruvate formate lyase I (NCBI) | compare |
| b3916 | pfkA | -3.7 | -2.5 | 6-phosphofructokinase (NCBI) | compare |
| b3052 | rfaE | -3.7 | -7.1 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b3035 | tolC | -3.6 | -10.4 | outer membrane channel; specific tolerance to colicin E1; segregation of daughter chromosomes (VIMSS) | compare |
| b2279 | nuoK | -3.6 | -2.2 | NADH dehydrogenase subunit K (NCBI) | compare |
| b0737 | tolQ | -3.6 | -2.2 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b3500 | gor | -3.6 | -1.7 | glutathione reductase (NCBI) | compare |
| b0902 | pflA | -3.6 | -10.3 | pyruvate formate lyase activating enzyme 1 (NCBI) | compare |
| b4201 | priB | -3.6 | -3.1 | primosomal replication protein N (NCBI) | compare |
| b4481 | rffT | -3.4 | -9.4 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b3778 | rep | -3.4 | -12.1 | DNA helicase and single-stranded DNA-dependent ATPase (NCBI) | compare |
| b3183 | obgE | -3.4 | -1.2 | GTPase involved in cell partioning and DNA repair (NCBI) | compare |
| b1677 | lpp | -3.4 | -2.8 | murein lipoprotein (NCBI) | compare |
| b2576 | srmB | -3.4 | -5.4 | ATP-dependent RNA helicase (NCBI) | compare |
| b1334 | fnr | -3.3 | -3.6 | DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) | compare |
| b3619 | rfaD | -3.3 | -3.9 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b1685 | ydiH | -3.3 | -1.9 | predicted protein (RefSeq) | compare |
| b3387 | dam | -3.3 | -14.5 | DNA adenine methylase (NCBI) | compare |
| b1236 | galU | -3.3 | -8.0 | glucose-1-phosphate uridylyltransferase (NCBI) | compare |
| b1861 | ruvA | -3.2 | -1.2 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b0739 | tolA | -3.2 | -3.7 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b2518 | ndk | -3.1 | -3.4 | nucleoside diphosphate kinase (NCBI) | compare |
| b0462 | acrB | -3.1 | -19.8 | multidrug efflux system protein (NCBI) | compare |
| b0463 | acrA | -3.0 | -14.1 | multidrug efflux system (NCBI) | compare |
| b0741 | pal | -3.0 | -5.2 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b2512 | yfgL | -3.0 | -8.0 | protein assembly complex, lipoprotein component (NCBI) | compare |
| b3181 | greA | -3.0 | -4.3 | transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) | compare |
| b0688 | pgm | -3.0 | -4.8 | phosphoglucomutase (NCBI) | compare |
| b1863 | ruvC | -3.0 | -2.1 | Holliday junction resolvase (NCBI) | compare |
| b3631 | rfaG | -2.9 | -18.2 | glucosyltransferase I (NCBI) | compare |
| b0740 | tolB | -2.9 | -5.2 | translocation protein TolB precursor (NCBI) | compare |
| b1187 | fadR | -2.8 | -5.4 | fatty acid metabolism regulator (NCBI) | compare |
| b4025 | pgi | -2.8 | -11.3 | glucose-6-phosphate isomerase (NCBI) | compare |
| b0014 | dnaK | -2.8 | -2.3 | molecular chaperone DnaK (NCBI) | compare |
| b1241 | adhE | -2.8 | -11.7 | fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase (NCBI) | compare |
| b3162 | deaD | -2.8 | -5.6 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b2569 | lepA | -2.8 | -6.4 | GTP-binding protein LepA (NCBI) | compare |
| b1192 | ldcA | -2.8 | -5.2 | L,D-carboxypeptidase A (NCBI) | compare |
| b0149 | mrcB | -2.7 | -14.1 | penicillin-binding protein 1b (NCBI) | compare |
| b3493 | pitA | -2.7 | -10.7 | phosphate transporter, low-affinity (NCBI) | compare |
| b2501 | ppk | -2.7 | -11.8 | polyphosphate kinase (NCBI) | compare |
| b3026 | qseC | -2.6 | -5.7 | sensory histidine kinase in two-component regulatory system with QseB (NCBI) | compare |
| b1860 | ruvB | -2.6 | -1.0 | Holliday junction DNA helicase B (NCBI) | compare |
| b0386 | proC | -2.6 | -5.4 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b3871 | bipA | -2.6 | -11.0 | GTP-binding protein (NCBI) | compare |
| b4171 | miaA | -2.6 | -3.0 | tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) | compare |
| b1361 | ydaW | -2.5 | -0.7 | orf, hypothetical protein (VIMSS) | compare |
| b1292 | sapC | -2.5 | -2.5 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1279 | yciS | -2.5 | -1.2 | conserved inner membrane protein (NCBI) | compare |
| b0049 | apaH | -2.5 | -3.1 | diadenosinetetraphosphatase (NCBI) | compare |
| b3838 | tatB | -2.4 | -6.3 | sec-independent translocase (NCBI) | compare |
| b3390 | aroK | -2.4 | -1.8 | shikimate kinase I (NCBI) | compare |
| b2620 | smpB | -2.4 | -0.8 | SsrA-binding protein (NCBI) | compare |
| b3860 | dsbA | -2.4 | -8.6 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b2330 | yfcB | -2.3 | -1.1 | putative adenine-specific methylase (VIMSS) | compare |
| b3652 | recG | -2.3 | -10.4 | ATP-dependent DNA helicase (NCBI) | compare |
| b3630 | rfaP | -2.3 | -13.7 | kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) | compare |
| b3613 | yibP | -2.3 | -1.6 | putative membrane protein (VIMSS) | compare |
| b2808 | gcvA | -2.3 | -4.7 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b4699 | fnrS | -2.3 | -0.9 | FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) | compare |
| b3405 | ompR | -2.2 | -5.3 | osmolarity response regulator (NCBI) | compare |
| b0738 | tolR | -2.2 | -3.7 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b1176 | minC | -2.1 | -3.9 | septum formation inhibitor (NCBI) | compare |
| b3927 | glpF | -2.1 | -10.3 | glycerol facilitator (NCBI) | compare |
| b3806 | cyaA | -2.0 | -8.2 | adenylate cyclase (NCBI) | compare |
| b0888 | trxB | -2.0 | -2.8 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b0088 | murD | -2.0 | -2.2 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) | compare |
| b1865 | nudB | -1.9 | -1.9 | dATP pyrophosphohydrolase (NCBI) | compare |
| b1831 | proQ | -1.9 | -4.0 | putative solute/DNA competence effector (NCBI) | compare |
| b1185 | dsbB | -1.9 | -3.6 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b2830 | nudH | -1.9 | -1.3 | dinucleoside polyphosphate hydrolase (NCBI) | compare |
| b0683 | fur | -1.9 | -0.9 | ferric uptake regulator (NCBI) | compare |
| b1286 | rnb | -1.9 | -3.1 | exoribonuclease II (NCBI) | compare |
| b3396 | mrcA | -1.9 | -13.8 | peptidoglycan synthetase; penicillin-binding protein 1A (VIMSS) | compare |
| b0912 | ihfB | -1.9 | -4.0 | integration host factor subunit beta (NCBI) | compare |
| b2894 | xerD | -1.8 | -0.7 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b4203 | rplI | -1.8 | -4.2 | 50S ribosomal protein L9 (NCBI) | compare |
| b1129 | phoQ | -1.8 | -1.3 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b3870 | glnA | -1.8 | -3.7 | glutamine synthetase (NCBI) | compare |
| b4139 | aspA | -1.8 | -9.4 | aspartate ammonia-lyase (aspartase) (VIMSS) | compare |
| b3147 | yraM | -1.8 | -10.3 | hypothetical protein (NCBI) | compare |
| b4480 | hdfR | -1.8 | -5.5 | transcriptional regulator HdfR (NCBI) | compare |
| b3863 | polA | -1.8 | -0.8 | DNA polymerase I (NCBI) | compare |
| b1175 | minD | -1.8 | -4.3 | membrane ATPase of the MinC-MinD-MinE system (NCBI) | compare |
| b1346 | ydaQ | -1.8 | -1.7 | orf, hypothetical protein (VIMSS) | compare |
| b0548 | ninE | -1.8 | -3.1 | DLP12 prophage; conserved protein (NCBI) | compare |
| b1712 | ihfA | -1.8 | -1.4 | integration host factor subunit alpha (NCBI) | compare |
| b0082 | mraW | -1.8 | -3.3 | S-adenosyl-methyltransferase (NCBI) | compare |
| b2616 | recN | -1.8 | -9.0 | recombination and repair protein (NCBI) | compare |
| b3781 | trxA | -1.7 | -3.5 | thioredoxin 1 (VIMSS) | compare |
| b0145 | dksA | -1.7 | -3.2 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b0721 | sdhC | -1.7 | -4.2 | succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) | compare |
| b3726 | pstA | -1.7 | -5.0 | phosphate transporter subunit (NCBI) | compare |
| b1523 | yneG | -1.7 | -1.9 | hypothetical protein (NCBI) | compare |
| b3933 | ftsN | -1.7 | -7.6 | essential cell division protein (NCBI) | compare |
| b4041 | plsB | -1.7 | -1.7 | glycerol-3-phosphate acyltransferase (VIMSS) | compare |
| b0726 | sucA | -1.7 | -5.0 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b3977 | tyrU | -1.6 | -0.7 | tRNA-Tyr (NCBI) | compare |
| b3706 | trmE | -1.6 | -3.4 | tRNA modification GTPase (NCBI) | compare |
| b2284 | nuoF | -1.6 | -4.2 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b0724 | sdhB | -1.6 | -7.0 | succinate dehydrogenase, FeS subunit (NCBI) | compare |
| b2285 | nuoE | -1.6 | -2.1 | NADH dehydrogenase subunit E (NCBI) | compare |
| b1290 | sapF | -1.6 | -1.4 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0051 | ksgA | -1.6 | -4.4 | dimethyladenosine transferase (NCBI) | compare |
| b2897 | ygfY | -1.6 | -3.3 | hypothetical protein (NCBI) | compare |
| b4603 | rseX | -1.6 | -0.7 | sRNA regulating ompA and ompC translation, with Hfq (RefSeq) | compare |
| b3935 | priA | -1.6 | -2.8 | primosome assembly protein PriA (NCBI) | compare |
| b2277 | nuoM | -1.6 | -5.9 | NADH dehydrogenase subunit M (NCBI) | compare |
| b3388 | damX | -1.6 | -10.2 | hypothetical protein (NCBI) | compare |
| b4655 | ythA | -1.5 | -1.8 | expressed protein (RefSeq) | compare |
| b2937 | speB | -1.5 | -5.4 | agmatinase (NCBI) | compare |
| b2846 | yqeH | -1.5 | -0.4 | orf, hypothetical protein (VIMSS) | compare |
| b3842 | rfaH | -1.5 | -4.9 | transcriptional activator RfaH (NCBI) | compare |
| b4202 | rpsR | -1.5 | -1.3 | 30S ribosomal protein S18 (NCBI) | compare |
| b0237 | pepD | -1.5 | -5.9 | aminoacyl-histidine dipeptidase (peptidase D) (NCBI) | compare |
| b2280 | nuoJ | -1.5 | -5.2 | NADH dehydrogenase subunit J (NCBI) | compare |
| b2276 | nuoN | -1.5 | -4.9 | NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) | compare |
| b1095 | fabF | -1.5 | -6.5 | 3-oxoacyl-(acyl carrier protein) synthase (NCBI) | compare |
| b2189 | proL | -1.5 | -1.6 | tRNA-Pro (NCBI) | compare |
| b0730 | mngR | -1.5 | -1.9 | DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) | compare |
| b1424 | mdoD | -1.4 | -5.2 | glucan biosynthesis protein, periplasmic (RefSeq) | compare |
| b4593 | ymgI | -1.4 | -1.0 | hypothetical protein (RefSeq) | compare |
| b1084 | rne | -1.4 | -3.6 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b2617 | smpA | -1.4 | -2.6 | small membrane protein A (VIMSS) | compare |
| b3005 | exbD | -1.4 | -4.4 | membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) | compare |
| b4685 | yrbN | -1.4 | -2.5 | expressed protein (RefSeq) | compare |
| b2286 | nuoC | -1.4 | -5.7 | NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) | compare |
| b2579 | yfiD | -1.4 | -2.3 | pyruvate formate lyase subunit (NCBI) | compare |
| b0723 | sdhA | -1.4 | -8.4 | succinate dehydrogenase flavoprotein subunit (NCBI) | compare |
| b1058 | yceO | -1.4 | -0.3 | hypothetical protein (NCBI) | compare |
| b1536 | ydeI | -1.4 | -1.2 | hypothetical protein (NCBI) | compare |
| b1278 | pgpB | -1.4 | -2.5 | phosphatidylglycerophosphatase B (NCBI) | compare |
| b0949 | uup | -1.4 | -7.5 | fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) | compare |
| b0819 | ybiS | -1.4 | -5.6 | hypothetical protein (NCBI) | compare |
| b0720 | gltA | -1.4 | -5.8 | citrate synthase (NCBI) | compare |
| b2288 | nuoA | -1.4 | -2.7 | NADH dehydrogenase I chain A (VIMSS) | compare |
| b1231 | tyrT | -1.4 | -0.8 | tRNA-Tyr (NCBI) | compare |
| b3021 | ygiT | -1.4 | -3.5 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b0200 | gmhB | -1.4 | -0.7 | hypothetical protein (NCBI) | compare |
| b1252 | tonB | -1.4 | -3.8 | membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) | compare |
| b2281 | nuoI | -1.4 | -2.5 | NADH dehydrogenase subunit I (NCBI) | compare |
| b2071 | yegJ | -1.4 | -1.6 | hypothetical protein (NCBI) | compare |
| b4375 | prfC | -1.4 | -0.9 | peptide chain release factor 3 (NCBI) | compare |
| b3389 | aroB | -1.3 | -7.2 | 3-dehydroquinate synthase (NCBI) | compare |
| b2893 | dsbC | -1.3 | -6.1 | protein disulfide isomerase II (NCBI) | compare |
| b0133 | panC | -1.3 | -6.0 | pantoate--beta-alanine ligase (NCBI) | compare |
| b2283 | nuoG | -1.3 | -6.3 | NADH:ubiquinone oxidoreductase, chain G (RefSeq) | compare |
| b0908 | aroA | -1.3 | -6.6 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b4179 | vacB | -1.3 | -5.9 | putative enzyme (VIMSS) | compare |
| b3803 | hemX | -1.3 | -7.2 | predicted uroporphyrinogen III methylase (NCBI) | compare |
| b2905 | gcvT | -1.3 | -5.2 | glycine cleavage system aminomethyltransferase T (NCBI) | compare |
| b1505 | ydeT | -1.3 | -1.7 | hypothetical protein (RefSeq) | compare |
| b0142 | folK | -1.3 | -0.5 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b4234 | yjgA | -1.3 | -3.9 | hypothetical protein (NCBI) | compare |
| b2007 | yeeX | -1.3 | -1.6 | conserved protein (RefSeq) | compare |
| b3438 | gntR | -1.3 | -5.4 | DNA-binding transcriptional repressor (NCBI) | compare |
| b4676 | yoaK | -1.3 | -0.6 | expressed protein (RefSeq) | compare |
| b2287 | nuoB | -1.3 | -2.4 | NADH dehydrogenase subunit B (NCBI) | compare |
| b2699 | recA | -1.3 | -0.7 | recombinase A (NCBI) | compare |
| b3868 | glnG | -1.3 | -3.7 | fused DNA-binding response regulator in two-component regulatory system with GlnL: response regulator/sigma54 interaction protein (NCBI) | compare |
| b1101 | ptsG | -1.3 | -7.2 | fused glucose-specific PTS enzymes: IIB component/IIC component (NCBI) | compare |
| b4042 | dgkA | -1.3 | -0.8 | diacylglycerol kinase (NCBI) | compare |
| b0059 | hepA | -1.3 | -9.2 | ATP-dependent helicase HepA (NCBI) | compare |
| b3642 | pyrE | -1.3 | -3.6 | orotate phosphoribosyltransferase (NCBI) | compare |
| b2498 | upp | -1.3 | -2.7 | uracil phosphoribosyltransferase (VIMSS) | compare |
| b3414 | gntY | -1.3 | -4.3 | predicted gluconate transport associated protein (NCBI) | compare |
| b4613 | dinQ | -1.3 | -1.7 | Damage inducible, function unknown (RefSeq) | compare |
| b3624 | rfaZ | -1.3 | -3.5 | lipopolysaccharide core biosynthesis protein (NCBI) | compare |
| b3237 | argR | -1.2 | -4.0 | arginine repressor (NCBI) | compare |
| b0015 | dnaJ | -1.2 | -6.4 | chaperone Hsp40, co-chaperone with DnaK (NCBI) | compare |
| b1281 | pyrF | -1.2 | -3.2 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b3844 | fre | -1.2 | -4.4 | NAD(P)H-flavin reductase (NCBI) | compare |
| b0143 | pcnB | -1.2 | -3.8 | poly(A) polymerase I (VIMSS) | compare |
| b2804 | fucU | -1.2 | -2.1 | L-fucose mutarotase (NCBI) | compare |
| b3858 | yihD | -1.2 | -2.7 | hypothetical protein (NCBI) | compare |
| b1130 | phoP | -1.2 | -2.0 | DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) | compare |
| b2278 | nuoL | -1.2 | -7.3 | NADH dehydrogenase subunit L (NCBI) | compare |
| b2479 | gcvR | -1.2 | -4.7 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b1482 | osmC | -1.2 | -2.1 | osmotically inducible, stress-inducible membrane protein (NCBI) | compare |