| | gene | name | fitness | t score | description | |
|---|
| b2476 | purC | -9.2 | -4.8 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b0523 | purE | -8.7 | -6.0 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b4232 | fbp | -8.7 | -10.4 | fructose-1,6-bisphosphatase (NCBI) | compare |
| b0033 | carB | -8.6 | -14.5 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b4006 | purH | -8.6 | -5.9 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b0912 | ihfB | -8.5 | -5.9 | integration host factor subunit beta (NCBI) | compare |
| b4005 | purD | -8.4 | -5.8 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b2312 | purF | -8.3 | -5.7 | amidophosphoribosyltransferase (NCBI) | compare |
| b1192 | ldcA | -8.2 | -5.7 | L,D-carboxypeptidase A (NCBI) | compare |
| b0522 | purK | -8.2 | -5.6 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b2557 | purL | -7.9 | -7.7 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b4245 | pyrB | -7.7 | -13.8 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b1062 | pyrC | -7.7 | -10.5 | dihydroorotase (NCBI) | compare |
| b2499 | purM | -7.7 | -5.3 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b0729 | sucD | -7.6 | -5.3 | succinyl-CoA synthetase subunit alpha (NCBI) | compare |
| b0817 | mntR | -7.5 | -6.6 | DNA-binding transcriptional regulator of mntH (NCBI) | compare |
| b0945 | pyrD | -7.3 | -7.2 | dihydroorotate dehydrogenase (NCBI) | compare |
| b1281 | pyrF | -7.3 | -6.9 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b2500 | purN | -7.0 | -8.6 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b0728 | sucC | -6.9 | -11.4 | succinyl-CoA synthetase subunit beta (NCBI) | compare |
| b3642 | pyrE | -6.8 | -8.1 | orotate phosphoribosyltransferase (NCBI) | compare |
| b0437 | clpP | -6.5 | -4.5 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b3236 | mdh | -6.5 | -13.9 | malate dehydrogenase (NCBI) | compare |
| b4139 | aspA | -6.3 | -15.8 | aspartate ammonia-lyase (aspartase) (VIMSS) | compare |
| b2282 | nuoH | -5.9 | -4.1 | NADH dehydrogenase subunit H (NCBI) | compare |
| b2188 | yejM | -5.9 | -17.5 | predicted hydrolase, inner membrane (NCBI) | compare |
| b0080 | fruR | -5.6 | -12.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2286 | nuoC | -5.6 | -9.3 | NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) | compare |
| b0438 | clpX | -5.5 | -9.9 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b0740 | tolB | -5.5 | -5.3 | translocation protein TolB precursor (NCBI) | compare |
| b0726 | sucA | -5.4 | -3.8 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b0032 | carA | -5.4 | -6.2 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b0741 | pal | -5.4 | -6.4 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b0928 | aspC | -5.3 | -8.1 | aspartate aminotransferase, PLP-dependent (NCBI) | compare |
| b0590 | fepD | -5.2 | -12.3 | iron-enterobactin transporter subunit (NCBI) | compare |
| b0737 | tolQ | -5.1 | -4.9 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0738 | tolR | -5.0 | -3.4 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b2287 | nuoB | -5.0 | -6.8 | NADH dehydrogenase subunit B (NCBI) | compare |
| b2278 | nuoL | -4.9 | -14.1 | NADH dehydrogenase subunit L (NCBI) | compare |
| b0589 | fepG | -4.8 | -11.0 | iron-enterobactin transporter subunit (NCBI) | compare |
| b3390 | aroK | -4.8 | -4.5 | shikimate kinase I (NCBI) | compare |
| b2279 | nuoK | -4.8 | -3.9 | NADH dehydrogenase subunit K (NCBI) | compare |
| b0588 | fepC | -4.8 | -11.8 | iron-enterobactin transporter subunit (NCBI) | compare |
| b2276 | nuoN | -4.7 | -8.7 | NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) | compare |
| b0739 | tolA | -4.7 | -5.6 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b0439 | lon | -4.7 | -7.1 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b2283 | nuoG | -4.6 | -12.7 | NADH:ubiquinone oxidoreductase, chain G (RefSeq) | compare |
| b2284 | nuoF | -4.6 | -8.8 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b2281 | nuoI | -4.6 | -6.0 | NADH dehydrogenase subunit I (NCBI) | compare |
| b3792 | wzxE | -4.5 | -9.1 | O-antigen translocase (NCBI) | compare |
| b3414 | gntY | -4.4 | -11.4 | predicted gluconate transport associated protein (NCBI) | compare |
| b1235 | rssB | -4.4 | -11.0 | response regulator of RpoS (NCBI) | compare |
| b2280 | nuoJ | -4.2 | -6.6 | NADH dehydrogenase subunit J (NCBI) | compare |
| b0592 | fepB | -4.1 | -10.3 | iron-enterobactin transporter subunit (NCBI) | compare |
| b1677 | lpp | -4.0 | -4.1 | murein lipoprotein (NCBI) | compare |
| b0723 | sdhA | -3.8 | -12.2 | succinate dehydrogenase flavoprotein subunit (NCBI) | compare |
| b2277 | nuoM | -3.8 | -10.5 | NADH dehydrogenase subunit M (NCBI) | compare |
| b2285 | nuoE | -3.8 | -4.0 | NADH dehydrogenase subunit E (NCBI) | compare |
| b0724 | sdhB | -3.4 | -8.1 | succinate dehydrogenase, FeS subunit (NCBI) | compare |
| b2567 | rnc | -3.4 | -2.3 | ribonuclease III (NCBI) | compare |
| b0585 | fes | -3.3 | -5.7 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b1712 | ihfA | -3.3 | -2.3 | integration host factor subunit alpha (NCBI) | compare |
| b0721 | sdhC | -3.3 | -3.5 | succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) | compare |
| b1291 | sapD | -3.3 | -3.7 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3979 | thrT | -3.2 | -1.1 | tRNA-Thr (NCBI) | compare |
| b3806 | cyaA | -3.2 | -9.0 | adenylate cyclase (NCBI) | compare |
| b2912 | ygfA | -3.1 | -5.8 | putative ligase (VIMSS) | compare |
| b3237 | argR | -3.1 | -7.1 | arginine repressor (NCBI) | compare |
| b2584 | yfiQ | -3.1 | -13.6 | fused predicted acyl-CoA synthetase: NAD(P)-binding subunit/ATP-binding subunit (NCBI) | compare |
| b3728 | pstS | -3.0 | -2.9 | phosphate transporter subunit (NCBI) | compare |
| b2518 | ndk | -3.0 | -3.7 | nucleoside diphosphate kinase (NCBI) | compare |
| b0722 | sdhD | -2.9 | -5.9 | succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) | compare |
| b2329 | aroC | -2.9 | -6.3 | chorismate synthase (NCBI) | compare |
| b0564 | appY | -2.7 | -1.1 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b3844 | fre | -2.7 | -9.3 | NAD(P)H-flavin reductase (NCBI) | compare |
| b0232 | yafN | -2.7 | -1.3 | predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) | compare |
| b2313 | cvpA | -2.6 | -4.0 | membrane protein required for colicin V production (NCBI) | compare |
| b2288 | nuoA | -2.6 | -3.0 | NADH dehydrogenase I chain A (VIMSS) | compare |
| b2501 | ppk | -2.6 | -9.8 | polyphosphate kinase (NCBI) | compare |
| b0683 | fur | -2.6 | -2.3 | ferric uptake regulator (NCBI) | compare |
| b3169 | nusA | -2.6 | -3.6 | transcription elongation factor NusA (NCBI) | compare |
| b3021 | ygiT | -2.6 | -3.0 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b0401 | brnQ | -2.6 | -10.9 | predicted branched chain amino acid transporter (LIV-II) (NCBI) | compare |
| b4042 | dgkA | -2.6 | -3.5 | diacylglycerol kinase (NCBI) | compare |
| b3082 | ygjM | -2.6 | -3.9 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2330 | yfcB | -2.5 | -3.0 | putative adenine-specific methylase (VIMSS) | compare |
| b1187 | fadR | -2.5 | -3.6 | fatty acid metabolism regulator (NCBI) | compare |
| b0676 | nagC | -2.5 | -11.3 | DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) | compare |
| b1882 | cheY | -2.5 | -1.1 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b4246 | pyrL | -2.4 | -2.6 | pyrBI operon leader peptide (NCBI) | compare |
| b4676 | yoaK | -2.4 | -1.1 | expressed protein (RefSeq) | compare |
| b1821 | b1821 | -2.4 | -6.9 | orf, hypothetical protein (VIMSS) | compare |
| b2937 | speB | -2.4 | -8.1 | agmatinase (NCBI) | compare |
| b0114 | aceE | -2.3 | -1.6 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b0908 | aroA | -2.3 | -11.1 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b3389 | aroB | -2.3 | -11.2 | 3-dehydroquinate synthase (NCBI) | compare |
| b3839 | tatC | -2.3 | -8.0 | TatABCE protein translocation system subunit (NCBI) | compare |
| b3290 | trkA | -2.2 | -4.0 | potassium transporter peripheral membrane component (NCBI) | compare |
| b0890 | ftsK | -2.2 | -7.9 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b0677 | nagA | -2.2 | -9.3 | N-acetylglucosamine-6-phosphate deacetylase (NCBI) | compare |
| b3281 | aroE | -2.2 | -15.2 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b2830 | nudH | -2.2 | -2.6 | dinucleoside polyphosphate hydrolase (NCBI) | compare |
| b1861 | ruvA | -2.1 | -2.8 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b2620 | smpB | -2.1 | -2.2 | SsrA-binding protein (NCBI) | compare |
| b0121 | speE | -2.1 | -8.0 | spermidine synthase (NCBI) | compare |
| b0428 | cyoE | -2.1 | -7.0 | protoheme IX farnesyltransferase (NCBI) | compare |
| b2318 | truA | -2.0 | -4.8 | tRNA pseudouridine synthase A (NCBI) | compare |
| b2699 | recA | -2.0 | -2.0 | recombinase A (NCBI) | compare |
| b3204 | ptsN | -2.0 | -5.7 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b1292 | sapC | -2.0 | -3.3 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3601 | mtlR | -2.0 | -7.6 | DNA-binding repressor (NCBI) | compare |
| b0720 | gltA | -2.0 | -7.1 | citrate synthase (NCBI) | compare |
| b1551 | b1551 | -2.0 | -1.2 | orf, hypothetical protein (VIMSS) | compare |
| b0149 | mrcB | -2.0 | -11.8 | penicillin-binding protein 1b (NCBI) | compare |
| b0088 | murD | -1.9 | -3.1 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) | compare |
| b4208 | cycA | -1.9 | -10.5 | D-alanine/D-serine/glycine transporter (NCBI) | compare |
| b2820 | recB | -1.9 | -2.2 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b3962 | udhA | -1.9 | -7.8 | putative oxidoreductase (VIMSS) | compare |
| b1103 | ycfF | -1.9 | -1.5 | orf, hypothetical protein (VIMSS) | compare |
| b3052 | rfaE | -1.9 | -6.0 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b4155 | yjeA | -1.9 | -1.3 | putative lysyl-tRNA synthetase (VIMSS) | compare |
| b4177 | purA | -1.9 | -1.3 | adenylosuccinate synthetase (NCBI) | compare |
| b3961 | oxyR | -1.8 | -10.4 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2576 | srmB | -1.8 | -4.5 | ATP-dependent RNA helicase (NCBI) | compare |
| b0431 | cyoB | -1.8 | -12.7 | cytochrome o ubiquinol oxidase subunit I (NCBI) | compare |
| b2021 | hisC | -1.8 | -5.8 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b0429 | cyoD | -1.8 | -4.3 | cytochrome o ubiquinol oxidase subunit IV (NCBI) | compare |
| b0430 | cyoC | -1.8 | -5.1 | cytochrome o ubiquinol oxidase subunit III (NCBI) | compare |
| b4375 | prfC | -1.8 | -6.6 | peptide chain release factor 3 (NCBI) | compare |
| b1857 | yebL | -1.8 | -8.4 | putative adhesin (VIMSS) | compare |
| b3613 | yibP | -1.8 | -5.3 | putative membrane protein (VIMSS) | compare |
| b1693 | aroD | -1.8 | -7.2 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b1058 | yceO | -1.8 | -0.8 | hypothetical protein (NCBI) | compare |
| b1290 | sapF | -1.8 | -3.0 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1084 | rne | -1.8 | -5.5 | fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) | compare |
| b0120 | speD | -1.8 | -10.9 | S-adenosylmethionine decarboxylase proenzyme (NCBI) | compare |
| b1105 | ycfM | -1.7 | -5.2 | predicted outer membrane lipoprotein (NCBI) | compare |
| b0750 | nadA | -1.7 | -9.4 | quinolinate synthetase (NCBI) | compare |
| b4388 | serB | -1.7 | -8.4 | 3-phosphoserine phosphatase (NCBI) | compare |
| b1524 | yneH | -1.7 | -1.5 | predicted glutaminase (NCBI) | compare |
| b3621 | rfaC | -1.7 | -7.0 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b2168 | fruK | -1.7 | -1.9 | 1-phosphofructokinase (NCBI) | compare |
| b3849 | trkH | -1.7 | -9.2 | potassium transporter (NCBI) | compare |
| b3619 | rfaD | -1.6 | -4.9 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b1611 | fumC | -1.6 | -5.5 | fumarate hydratase (NCBI) | conserved |
| b2064 | asmA | -1.6 | -7.6 | predicted assembly protein (NCBI) | compare |
| b0222 | lpcA | -1.6 | -4.3 | phosphoheptose isomerase (NCBI) | compare |
| b1545 | pinQ | -1.6 | -0.5 | Qin prophage; predicted site-specific recombinase (NCBI) | compare |
| b0432 | cyoA | -1.6 | -8.9 | cytochrome o ubiquinol oxidase subunit II (NCBI) | compare |
| b1859 | znuB | -1.6 | -6.8 | high-affinity zinc transporter membrane component (NCBI) | compare |
| b2853 | ygeI | -1.6 | -0.8 | hypothetical protein (NCBI) | compare |
| b3764 | yifE | -1.6 | -5.2 | hypothetical protein (NCBI) | compare |
| b0049 | apaH | -1.5 | -3.8 | diadenosinetetraphosphatase (NCBI) | compare |
| b1502 | ydeQ | -1.5 | -3.6 | predicted fimbrial-like adhesin protein (NCBI) | compare |
| b1285 | gmr | -1.5 | -6.2 | modulator of Rnase II stability (NCBI) | compare |
| b0145 | dksA | -1.5 | -2.9 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b3386 | rpe | -1.5 | -1.0 | ribulose-phosphate 3-epimerase (NCBI) | compare |
| b4146 | yjeK | -1.5 | -3.6 | predicted lysine aminomutase (NCBI) | compare |
| b3726 | pstA | -1.5 | -4.3 | phosphate transporter subunit (NCBI) | compare |
| b1858 | znuC | -1.5 | -4.7 | high-affinity zinc transporter ATPase (NCBI) | compare |
| b1165 | ymgA | -1.4 | -0.9 | hypothetical protein (NCBI) | compare |
| b3706 | trmE | -1.4 | -4.9 | tRNA modification GTPase (NCBI) | compare |
| b0427 | yajR | -1.4 | -8.8 | putative transport protein (VIMSS) | compare |
| b1351 | racC | -1.4 | -0.9 | Rac prophage; predicted protein (NCBI) | compare |
| b0226 | dinJ | -1.4 | -5.1 | predicted antitoxin of YafQ-DinJ toxin-antitoxin system (NCBI) | compare |
| b0880 | cspD | -1.4 | -2.8 | cold shock protein homolog (NCBI) | compare |
| b2569 | lepA | -1.4 | -3.9 | GTP-binding protein LepA (NCBI) | compare |
| b0303 | ykgI | -1.4 | -0.9 | orf, hypothetical protein (VIMSS) | compare |
| b2846 | yqeH | -1.4 | -0.9 | orf, hypothetical protein (VIMSS) | compare |
| b4179 | vacB | -1.3 | -4.9 | putative enzyme (VIMSS) | compare |
| b3232 | yhcM | -1.3 | -9.0 | conserved protein with nucleoside triphosphate hydrolase domain (NCBI) | compare |
| b3500 | gor | -1.3 | -2.0 | glutathione reductase (NCBI) | compare |
| b3708 | tnaA | -1.3 | -11.1 | tryptophanase (VIMSS) | compare |
| b2897 | ygfY | -1.3 | -3.2 | hypothetical protein (NCBI) | compare |
| b3164 | pnp | -1.3 | -2.3 | polynucleotide phosphorylase/polyadenylase (RefSeq) | compare |
| b2350 | yfdG | -1.3 | -4.6 | CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) | compare |
| b2022 | hisB | -1.3 | -6.2 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2025 | hisF | -1.3 | -3.6 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b1293 | sapB | -1.3 | -1.9 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b4481 | rffT | -1.3 | -6.1 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b2291 | yfbR | -1.3 | -4.3 | hypothetical protein (NCBI) | compare |
| b3725 | pstB | -1.2 | -0.9 | phosphate transporter subunit (NCBI) | compare |
| b2894 | xerD | -1.2 | -1.1 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b2913 | serA | -1.2 | -7.1 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b1679 | sufE | -1.2 | -2.6 | cysteine desufuration protein SufE (NCBI) | compare |
| b1855 | lpxM | -1.2 | -5.0 | lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) | compare |
| b1190 | dadX | -1.2 | -4.1 | alanine racemase (NCBI) | compare |
| b2822 | recC | -1.2 | -4.9 | exonuclease V (RecBCD complex), gamma chain (NCBI) | compare |
| b4039 | ubiC | -1.2 | -5.3 | chorismate lyase (VIMSS) | compare |
| b1680 | sufS | -1.2 | -5.3 | selenocysteine lyase (NCBI) | compare |
| b1014 | putA | -1.2 | -9.0 | fused DNA-binding transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase (NCBI) | conserved |
| b3811 | xerC | -1.2 | -2.3 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b0460 | hha | -1.2 | -3.6 | modulator of gene expression, with H-NS (NCBI) | compare |
| b2020 | hisD | -1.2 | -6.6 | histidinol dehydrogenase (NCBI) | compare |
| b1015 | putP | -1.2 | -7.2 | proline:sodium symporter (NCBI) | conserved |
| b2144 | sanA | -1.1 | -8.4 | hypothetical protein (NCBI) | compare |
| b1682 | sufC | -1.1 | -3.9 | cysteine desulfurase ATPase component (NCBI) | compare |
| b0109 | nadC | -1.1 | -6.2 | nicotinate-nucleotide pyrophosphorylase (NCBI) | compare |
| b3781 | trxA | -1.1 | -4.4 | thioredoxin 1 (VIMSS) | compare |
| b1361 | ydaW | -1.1 | -0.6 | orf, hypothetical protein (VIMSS) | compare |