Experiment set57IT040 for Escherichia coli BW25113

Compare to:

Ying_AminoAcid20 rep A; time point 3

200 most detrimental genes:

  gene name fitness t score description  
b3261 fis +2.8 10.5 DNA-binding protein Fis (NCBI) compare
b3753 rbsR +2.0 17.8 DNA-binding transcriptional repressor of ribose metabolism (NCBI) compare
b3229 sspA +2.0 9.7 stringent starvation protein A (NCBI) compare
b1823 cspC +1.9 4.3 stress protein, member of the CspA-family (NCBI) compare
b1831 proQ +1.9 6.0 putative solute/DNA competence effector (NCBI) compare
b0014 dnaK +1.5 6.4 molecular chaperone DnaK (NCBI) compare
b1095 fabF +1.5 11.5 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b1422 ydcI +1.5 7.4 putative transcriptional regulator LYSR-type (VIMSS) compare
b1822 rrmA +1.3 2.8 23S rRNA m1G745 methyltransferase (NCBI) compare
b0240 crl +1.3 8.3 DNA-binding transcriptional regulator (NCBI) compare
b1188 ycgB +1.2 7.0 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b3260 dusB +1.2 2.9 tRNA-dihydrouridine synthase B (NCBI) compare
b1038 csgF +1.2 4.2 predicted transport protein (NCBI) compare
b4552 yrhC +1.2 1.7 no description compare
b1783 yeaG +1.1 6.5 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b0382 yaiB +1.1 7.4 hypothetical protein (NCBI) compare
b3752 rbsK +1.1 6.6 ribokinase (NCBI) compare
b1784 yeaH +1.1 5.4 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b4450 arcZ +1.0 4.5 sRNA antisense regulator of tpx and sdaA, Hfq-dependent (RefSeq) compare
b4655 ythA +1.0 1.5 expressed protein (RefSeq) compare
b3206 npr +1.0 5.4 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) compare
b1824 yobF +1.0 4.2 hypothetical protein (NCBI) compare
b1072 flgA +1.0 3.4 flagellar basal body P-ring biosynthesis protein A (NCBI) compare
b1628 rsxB +0.9 4.6 electron transport complex protein RnfB (NCBI) compare
b1191 b1191 +0.9 6.4 orf, hypothetical protein (VIMSS) compare
b1037 csgG +0.9 7.8 outer membrane lipoprotein (NCBI) compare
b4402 yjjY +0.9 1.6 hypothetical protein (NCBI) compare
b1630 rsxD +0.9 4.4 electron transport complex protein RnfD (NCBI) compare
b3644 yicC +0.9 4.6 hypothetical protein (NCBI) compare
b0630 lipB +0.9 1.8 protein of lipoate biosynthesis (VIMSS) compare
b2829 ptsP +0.9 7.1 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b1236 galU +0.9 5.6 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0605 ahpC +0.9 3.9 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b2642 yfjW +0.9 1.0 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1083 flgL +0.8 4.1 flagellar hook-associated protein L (NCBI) compare
b4110 yjcZ +0.8 5.9 orf, hypothetical protein (VIMSS) compare
b1923 fliC +0.8 6.4 flagellin (NCBI) compare
b0661 miaB +0.8 6.0 isopentenyl-adenosine A37 tRNA methylthiolase (NCBI) compare
b1725 yniA +0.8 2.4 predicted phosphotransferase/kinase (NCBI) compare
b1418 cybB +0.8 2.0 cytochrome b(561) (VIMSS) compare
b1556 b1556 +0.8 3.0 orf, hypothetical protein (VIMSS) compare
b1709 btuD +0.8 1.1 vitamin B12-transporter ATPase (NCBI) compare
b1341 b1341 +0.8 5.6 orf, hypothetical protein (VIMSS) compare
b4217 ytfK +0.8 4.3 orf, hypothetical protein (VIMSS) compare
b1039 csgE +0.8 4.7 predicted transport protein (NCBI) compare
b1632 rsxE +0.8 5.7 NADH-ubiquinone oxidoreductase (NCBI) compare
b1613 manA +0.8 3.1 mannose-6-phosphate isomerase (VIMSS) compare
b2012 yeeD +0.8 3.0 hypothetical protein (NCBI) compare
b4094 phnN +0.8 2.2 ribose 1,5-bisphosphokinase (NCBI) compare
b1070 flgN +0.8 1.5 export chaperone for FlgK and FlgL (NCBI) compare
b1924 fliD +0.8 3.9 flagellar capping protein (NCBI) compare
b2535 csiE +0.7 6.4 orf, hypothetical protein (VIMSS) compare
b1332 ynaJ +0.7 0.8 predicted inner membrane protein (NCBI) compare
b2127 mlrA +0.7 4.8 DNA-binding transcriptional regulator (NCBI) compare
b1629 rsxC +0.7 4.3 electron transport complex protein RnfC (NCBI) compare
b3107 yhaL +0.7 1.5 orf, hypothetical protein (VIMSS) compare
b2262 menB +0.7 1.5 naphthoate synthase (NCBI) compare
b4071 nrfB +0.7 1.4 formate-dependent nitrite reductase; a penta-haeme cytochrome c (VIMSS) compare
b1085 b1085 +0.7 2.4 orf, hypothetical protein (VIMSS) compare
b2317 dedA +0.7 2.2 conserved inner membrane protein (NCBI) compare
b0059 hepA +0.7 6.4 ATP-dependent helicase HepA (NCBI) compare
b1450 b1450 +0.7 3.3 orf, hypothetical protein (VIMSS) compare
b4373 rimI +0.7 2.2 ribosomal-protein-alanine N-acetyltransferase (NCBI) compare
b0850 ybjC +0.7 2.6 predicted inner membrane protein (NCBI) compare
b2229 b2229 +0.7 2.1 orf, hypothetical protein (VIMSS) compare
b1954 dsrA +0.7 1.0 regulatory antisense RNA (NCBI) compare
b1890 motA +0.7 3.3 flagellar motor protein MotA (NCBI) compare
b3755 yieP +0.7 5.2 predicted transcriptional regulator (NCBI) compare
b1082 flgK +0.7 4.7 flagellar hook-associated protein K (NCBI) compare
b2742 nlpD +0.7 2.7 predicted outer membrane lipoprotein (NCBI) compare
b1247 oppF +0.7 2.9 oligopeptide transporter subunit (NCBI) compare
b3494 yhiO +0.7 3.6 universal stress protein UspB (NCBI) compare
b1818 manY +0.7 2.5 mannose-specific enzyme IIC component of PTS (NCBI) compare
b2067 yegE +0.7 5.0 predicted diguanylate cyclase, GGDEF domain signalling protein (NCBI) compare
b1244 oppB +0.7 4.6 oligopeptide permease ABC transporter membrane protein (NCBI) compare
b2911 ssrS +0.6 1.5 6S regulatory RNA (NCBI) compare
b1040 csgD +0.6 1.9 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b0406 tgt +0.6 4.2 queuine tRNA-ribosyltransferase (NCBI) compare
b4109 yjdA +0.6 5.5 conserved protein with nucleoside triphosphate hydrolase domain (NCBI) compare
b1946 fliN +0.6 3.1 flagellar motor switch protein (NCBI) compare
b1889 motB +0.6 3.9 flagellar motor protein MotB (NCBI) compare
b0881 clpS +0.6 1.7 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b1344 ydaO +0.6 1.9 predicted C32 tRNA thiolase (NCBI) compare
b1279 yciS +0.6 0.9 conserved inner membrane protein (NCBI) compare
b1685 ydiH +0.6 1.2 predicted protein (RefSeq) compare
b1171 b1171 +0.6 1.1 orf, hypothetical protein (VIMSS) compare
b1243 oppA +0.6 3.7 oligopeptide transporter subunit (NCBI) compare
b1842 holE +0.6 1.7 DNA polymerase III, theta subunit (NCBI) compare
b2007 yeeX +0.6 2.3 conserved protein (RefSeq) compare
b3963 fabR +0.6 4.7 DNA-binding transcriptional repressor (RefSeq) compare
b4171 miaA +0.6 2.3 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1939 fliG +0.6 3.3 flagellar motor switch protein G (NCBI) compare
b3181 greA +0.6 2.7 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b2218 rcsC +0.6 4.3 hybrid sensory kinase in two-component regulatory system with RcsB and YojN (RefSeq) compare
b1922 fliA +0.6 3.2 flagellar biosynthesis; alternative sigma factor 28; regulation of flagellar operons (VIMSS) compare
b1865 nudB +0.6 1.4 dATP pyrophosphohydrolase (NCBI) compare
b2954 yggV +0.6 1.5 putative deoxyribonucleotide triphosphate pyrophosphatase (NCBI) compare
b1380 ldhA +0.6 1.7 D-lactate dehydrogenase (NCBI) compare
b3119 tdcR +0.6 1.4 threonine dehydratase operon activator protein (VIMSS) compare
b1591 b1591 +0.6 1.6 putative oxidoreductase component (VIMSS) compare
b2446 yffO +0.5 1.8 CPZ-55 prophage; predicted protein (NCBI) compare
b0627 tatE +0.5 1.5 twin arginine translocase protein E (NCBI) compare
b4644 ypjI +0.5 2.8 no description compare
b4511 ybdZ +0.5 1.9 hypothetical protein (NCBI) compare
b1335 ogt +0.5 2.0 O-6-alkylguanine-DNA:cysteine-protein methyltransferase (NCBI) compare
b3545 proK +0.5 1.5 tRNA-Pro (NCBI) compare
b1242 ychE +0.5 2.5 predicted inner membrane protein (NCBI) compare
b0778 bioD +0.5 1.8 dethiobiotin synthetase (NCBI) compare
b2774 ygcW +0.5 2.4 putative oxidoreductase (VIMSS) compare
b0550 rusA +0.5 1.6 DLP12 prophage; endonuclease RUS (NCBI) compare
b3643 rph +0.5 1.4 ribonuclease PH (NCBI) compare
b3863 polA +0.5 0.8 DNA polymerase I (NCBI) compare
b2004 yeeU +0.5 1.5 CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system (NCBI) compare
b1079 flgH +0.5 2.2 flagellar L-ring protein precursor H (NCBI) compare
b3973 birA +0.5 1.7 biotin--protein ligase (NCBI) compare
b1848 yebG +0.5 1.0 conserved protein regulated by LexA (NCBI) compare
b1253 yciA +0.5 1.2 predicted hydrolase (NCBI) compare
b3933 ftsN +0.5 3.8 essential cell division protein (NCBI) compare
b2175 spr +0.5 2.1 predicted peptidase, outer membrane lipoprotein (NCBI) compare
b1569 dicC +0.5 2.2 Qin prophage; DNA-binding transcriptional regulator for DicB (NCBI) compare
b1941 fliI +0.5 3.6 flagellum-specific ATP synthase (NCBI) compare
b3404 envZ +0.5 3.4 osmolarity sensor protein (NCBI) compare
b1073 flgB +0.5 3.0 flagellar basal-body rod protein B (NCBI) compare
b1074 flgC +0.5 1.6 flagellar basal-body rod protein C (NCBI) compare
b1819 manZ +0.5 2.5 mannose-specific enzyme IID component of PTS (NCBI) compare
b1329 b1329 +0.5 3.0 putative transport periplasmic protein (VIMSS) compare
b1013 ycdC +0.5 1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b3398 yrfF +0.5 1.3 predicted inner membrane protein (NCBI) compare
b1945 fliM +0.5 3.5 flagellar motor switch protein M (NCBI) compare
b4370 leuQ +0.5 1.3 tRNA-Leu (NCBI) compare
b2114 metG +0.5 1.1 methionyl-tRNA synthetase (NCBI) compare
b0643 ybeL +0.5 2.5 hypothetical protein (NCBI) compare
b2910 zapA +0.5 2.3 protein that localizes to the cytokinetic ring (NCBI) compare
b1627 rsxA +0.5 2.2 Na(+)-translocating NADH-quinone reductase subunit E (NCBI) compare
b4594 ymgJ +0.5 1.4 hypothetical protein (RefSeq) compare
b1600 mdtJ +0.5 1.0 multidrug efflux system transporter (NCBI) compare
b1949 fliQ +0.5 1.2 flagellar biosynthesis protein Q (NCBI) compare
b0623 cspE +0.5 1.3 cold shock protein E (NCBI) compare
b1127 pepT +0.5 3.4 peptidase T (NCBI) compare
b2204 napH +0.4 2.0 quinol dehydrogenase membrane component (NCBI) compare
b4544 yfbW +0.4 2.3 hypothetical protein (NCBI) compare
b3498 prlC +0.4 3.8 oligopeptidase A (NCBI) compare
b2214 yojL +0.4 2.7 predicted thiamine biosynthesis lipoprotein (NCBI) compare
b3102 yqjG +0.4 2.5 predicted S-transferase (NCBI) compare
b2531 iscR +0.4 1.0 DNA-binding transcriptional repressor (NCBI) compare
b1916 sdiA +0.4 2.9 DNA-binding transcriptional activator (NCBI) compare
b1948 fliP +0.4 2.0 flagellar biosynthesis protein P (NCBI) compare
b0405 queA +0.4 2.4 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (NCBI) compare
b1359 ydaU +0.4 2.0 Rac prophage; conserved protein (NCBI) compare
b1041 csgB +0.4 2.0 curlin nucleator protein, minor subunit in curli complex (NCBI) compare
b1943 fliK +0.4 2.7 flagellar hook-length control protein (NCBI) compare
b3228 sspB +0.4 2.3 ClpXP protease specificity-enhancing factor (NCBI) compare
b4461 yfjD +0.4 2.9 predicted inner membrane protein (RefSeq) compare
b0975 hyaD +0.4 2.0 protein involved in processing of HyaA and HyaB proteins (NCBI) compare
b0160 dgt +0.4 4.0 deoxyguanosinetriphosphate triphosphohydrolase (NCBI) compare
b0920 ycbC +0.4 2.0 conserved inner membrane protein (NCBI) compare
b1742 b1742 +0.4 1.7 orf, hypothetical protein (VIMSS) compare
b0852 rimK +0.4 2.0 ribosomal protein S6 modification protein (NCBI) compare
b1763 topB +0.4 1.9 DNA topoisomerase III (NCBI) compare
b1514 lsrC +0.4 1.4 AI2 transporter (NCBI) compare
b2644 yfjY +0.4 1.1 CP4-57 prophage; predicted DNA repair protein (NCBI) compare
b2618 b2618 +0.4 1.1 orf, hypothetical protein (VIMSS) compare
b2051 wcaH +0.4 1.1 GDP-mannose mannosyl hydrolase (VIMSS) compare
b2953 yggU +0.4 1.4 orf, hypothetical protein (VIMSS) compare
b3133 agaV +0.4 0.9 PTS system, cytoplasmic, N-acetylgalactosamine-specific IIB component 2 (EIIB-AGA) (VIMSS) compare
b2784 relA +0.4 2.9 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b0225 yafQ +0.4 2.1 predicted toxin of the YafQ-DinJ toxin-antitoxin system (NCBI) compare
b1944 fliL +0.4 2.3 flagellar basal body-associated protein FliL (NCBI) compare
b1557 cspB +0.4 1.1 Qin prophage; cold shock protein (NCBI) compare
b0979 appB +0.4 2.5 cytochrome bd-II oxidase, subunit II (NCBI) compare
b3280 yrdB +0.4 2.1 hypothetical protein (NCBI) compare
b4543 ypaA +0.4 1.6 predicted protein (NCBI) compare
b2646 ypjF +0.4 1.3 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b1931 yedK +0.4 1.5 hypothetical protein (NCBI) compare
b0381 ddlA +0.4 2.7 D-alanylalanine synthetase (NCBI) compare
b3432 glgB +0.4 3.5 glycogen branching enzyme (NCBI) compare
b2419 yfeK +0.4 1.1 hypothetical protein (NCBI) compare
b1035 ycdY +0.4 2.9 hypothetical protein (NCBI) compare
b1642 slyA +0.4 0.9 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b1621 malX +0.4 2.5 fused maltose and glucose-specific PTS enzymes: IIB component -! IIC component (NCBI) compare
b0357 yaiN +0.4 1.2 putative alpha helix chain (VIMSS) compare
b1428 ydcK +0.4 2.4 predicted enzyme (NCBI) compare
b3156 yhbS +0.4 2.1 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b1358 ydaT +0.4 0.5 Rac prophage; predicted protein (NCBI) compare
b2080 b2080 +0.4 1.0 orf, hypothetical protein (VIMSS) compare
b1110 ycfJ +0.4 2.1 hypothetical protein (NCBI) compare
b1294 sapA +0.4 2.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2216 rcsD +0.4 3.0 phosphotransfer intermediate protein in two-component regulatory system with RcsBC (NCBI) compare
b1593 b1593 +0.4 1.7 orf, hypothetical protein (VIMSS) compare
b1879 flhA +0.4 2.3 flagellar biosynthesis protein A (NCBI) compare
b3995 rsd +0.4 2.3 stationary phase protein, binds sigma 70 RNA polymerase subunit (NCBI) compare
b4409 blr +0.4 2.5 beta-lactam resistance membrane protein (NCBI) compare
b1295 ymjA +0.4 1.2 hypothetical protein (NCBI) compare
b2377 yfdY +0.4 1.5 predicted inner membrane protein (NCBI) compare
b1156 tfaE +0.4 1.9 e14 prophage; predicted tail fiber assembly protein (NCBI) compare
b3190 yrbA +0.4 2.2 orf, hypothetical protein (VIMSS) compare
b2300 yfcE +0.4 0.7 orf, hypothetical protein (VIMSS) compare
b1521 uxaB +0.4 2.2 tagaturonate reductase (NCBI) compare
b1150 ymfR +0.4 0.5 e14 prophage; predicted protein (NCBI) compare
b4055 aphA +0.4 2.6 acid phosphatase/phosphotransferase, class B, non-specific (NCBI) compare


Specific Phenotypes

For 16 genes in this experiment

For carbon source Ying_AminoAcid20 in Escherichia coli BW25113

For carbon source Ying_AminoAcid20 across organisms