Experiment set57IT039 for Escherichia coli BW25113

Compare to:

Ying_all64 rep C; time point 3

200 most important genes:

  gene name fitness t score description  
b1192 ldcA -8.4 -5.8 L,D-carboxypeptidase A (NCBI) compare
b4208 cycA -6.9 -16.8 D-alanine/D-serine/glycine transporter (NCBI) conserved
b0438 clpX -6.5 -7.7 ATP-dependent protease ATP-binding subunit (NCBI) compare
b0741 pal -6.0 -5.9 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0737 tolQ -6.0 -4.1 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0740 tolB -5.9 -5.7 translocation protein TolB precursor (NCBI) compare
b3839 tatC -5.8 -8.9 TatABCE protein translocation system subunit (NCBI) compare
b4388 serB -5.8 -12.3 3-phosphoserine phosphatase (NCBI) compare
b3021 ygiT -5.8 -4.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b0739 tolA -5.6 -3.9 cell envelope integrity inner membrane protein TolA (NCBI) compare
b0907 serC -5.2 -8.7 phosphoserine aminotransferase (NCBI) compare
b0738 tolR -5.2 -3.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2912 ygfA -5.2 -6.2 putative ligase (VIMSS) compare
b0920 ycbC -5.1 -5.4 conserved inner membrane protein (NCBI) compare
b0912 ihfB -5.1 -5.9 integration host factor subunit beta (NCBI) compare
b3792 wzxE -4.9 -8.8 O-antigen translocase (NCBI) compare
b0683 fur -4.8 -4.4 ferric uptake regulator (NCBI) compare
b3390 aroK -4.4 -4.8 shikimate kinase I (NCBI) compare
b2830 nudH -4.3 -3.0 dinucleoside polyphosphate hydrolase (NCBI) compare
b0437 clpP -4.1 -11.1 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3162 deaD -3.9 -8.4 inducible ATP-independent RNA helicase (VIMSS) compare
b2913 serA -3.9 -12.0 D-3-phosphoglycerate dehydrogenase (NCBI) compare
b0688 pgm -3.8 -8.4 phosphoglucomutase (NCBI) compare
b0439 lon -3.8 -10.3 DNA-binding ATP-dependent protease La (NCBI) compare
b2935 tktA -3.7 -2.5 transketolase 1, thiamin-binding (NCBI) compare
b2576 srmB -3.7 -7.0 ATP-dependent RNA helicase (NCBI) compare
b0957 ompA -3.6 -4.9 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b2567 rnc -3.6 -2.5 ribonuclease III (NCBI) compare
b0726 sucA -3.5 -7.8 alpha-ketoglutarate decarboxylase (NCBI) compare
b3619 rfaD -3.5 -9.2 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b4042 dgkA -3.4 -3.3 diacylglycerol kinase (NCBI) compare
b2518 ndk -3.3 -5.2 nucleoside diphosphate kinase (NCBI) compare
b0678 nagB -3.3 -7.5 glucosamine-6-phosphate deaminase (NCBI) compare
b3183 obgE -3.3 -3.2 GTPase involved in cell partioning and DNA repair (NCBI) compare
b4202 rpsR -3.2 -3.1 30S ribosomal protein S18 (NCBI) compare
b2479 gcvR -3.2 -9.1 transcriptional regulation of gcv operon (VIMSS) compare
b3838 tatB -3.2 -6.7 sec-independent translocase (NCBI) compare
b0049 apaH -3.2 -6.4 diadenosinetetraphosphatase (NCBI) compare
b1712 ihfA -3.2 -3.1 integration host factor subunit alpha (NCBI) compare
b3916 pfkA -3.2 -5.3 6-phosphofructokinase (NCBI) compare
b0401 brnQ -3.2 -12.0 predicted branched chain amino acid transporter (LIV-II) (NCBI) compare
b3621 rfaC -3.1 -11.3 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b4375 prfC -3.1 -8.6 peptide chain release factor 3 (NCBI) compare
b0222 lpcA -3.1 -4.6 phosphoheptose isomerase (NCBI) compare
b3229 sspA -3.0 -6.4 stringent starvation protein A (NCBI) compare
b4685 yrbN -3.0 -6.0 expressed protein (RefSeq) compare
b3052 rfaE -2.9 -8.9 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0632 dacA -2.9 -10.9 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b2846 yqeH -2.8 -1.9 orf, hypothetical protein (VIMSS) compare
b0232 yafN -2.8 -1.6 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3613 yibP -2.8 -8.2 putative membrane protein (VIMSS) compare
b3169 nusA -2.8 -4.9 transcription elongation factor NusA (NCBI) compare
b3082 ygjM -2.7 -3.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b2894 xerD -2.7 -1.8 site-specific tyrosine recombinase XerD (NCBI) compare
b0890 ftsK -2.7 -8.8 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1830 prc -2.6 -9.3 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b3290 trkA -2.6 -3.6 potassium transporter peripheral membrane component (NCBI) compare
b1677 lpp -2.6 -4.0 murein lipoprotein (NCBI) compare
b2350 yfdG -2.5 -4.4 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) compare
b0114 aceE -2.5 -1.7 pyruvate dehydrogenase subunit E1 (NCBI) compare
b0724 sdhB -2.4 -7.6 succinate dehydrogenase, FeS subunit (NCBI) compare
b1236 galU -2.4 -9.1 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0677 nagA -2.4 -8.2 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b0200 gmhB -2.3 -3.4 hypothetical protein (NCBI) compare
b3811 xerC -2.3 -2.7 site-specific tyrosine recombinase XerC (NCBI) compare
b2820 recB -2.2 -2.2 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b1290 sapF -2.2 -3.2 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0080 fruR -2.2 -8.2 DNA-binding transcriptional dual regulator (NCBI) compare
b4239 treC -2.2 -3.0 trehalose-6-P hydrolase (NCBI) compare
b2937 speB -2.2 -8.6 agmatinase (NCBI) compare
b1551 b1551 -2.2 -1.4 orf, hypothetical protein (VIMSS) compare
b2569 lepA -2.1 -5.3 GTP-binding protein LepA (NCBI) compare
b2620 smpB -2.1 -2.3 SsrA-binding protein (NCBI) compare
b4647 mokA -2.0 -1.4 no description compare
b3620 rfaF -2.0 -7.3 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b0149 mrcB -2.0 -14.4 penicillin-binding protein 1b (NCBI) compare
b0730 mngR -2.0 -3.0 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b3204 ptsN -1.9 -6.3 sugar-specific enzyme IIA component of PTS (NCBI) compare
b0722 sdhD -1.9 -7.1 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b1058 yceO -1.9 -1.0 hypothetical protein (NCBI) compare
b3609 secB -1.9 -2.8 export protein SecB (NCBI) compare
b2699 recA -1.8 -2.1 recombinase A (NCBI) compare
b4177 purA -1.8 -1.8 adenylosuccinate synthetase (NCBI) compare
b1185 dsbB -1.8 -4.7 reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) compare
b0721 sdhC -1.8 -9.1 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b1545 pinQ -1.8 -0.6 Qin prophage; predicted site-specific recombinase (NCBI) compare
b1293 sapB -1.7 -2.0 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3806 cyaA -1.7 -7.4 adenylate cyclase (NCBI) compare
b1676 pykF -1.7 -6.7 pyruvate kinase (NCBI) compare
b3844 fre -1.7 -5.8 NAD(P)H-flavin reductase (NCBI) compare
b2290 yfbQ -1.7 -12.1 aspartate aminotransferase (NCBI) compare
b0723 sdhA -1.7 -10.6 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b1291 sapD -1.7 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b3163 nlpI -1.7 -6.0 hypothetical protein (NCBI) compare
b2853 ygeI -1.7 -1.1 hypothetical protein (NCBI) compare
b4481 rffT -1.7 -5.9 4-alpha-L-fucosyltransferase (NCBI) compare
b2144 sanA -1.7 -10.8 hypothetical protein (NCBI) compare
b3600 mtlD -1.6 -6.3 mannitol-1-phosphate 5-dehydrogenase (NCBI) compare
b0889 lrp -1.6 -2.9 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b3405 ompR -1.6 -6.1 osmolarity response regulator (NCBI) compare
b3979 thrT -1.6 -0.9 tRNA-Thr (NCBI) compare
b3386 rpe -1.6 -1.1 ribulose-phosphate 3-epimerase (NCBI) compare
b1088 yceD -1.6 -4.9 hypothetical protein (NCBI) compare
b1351 racC -1.5 -1.0 Rac prophage; predicted protein (NCBI) compare
b1165 ymgA -1.5 -1.0 hypothetical protein (NCBI) compare
b2329 aroC -1.5 -6.5 chorismate synthase (NCBI) compare
b3741 gidA -1.5 -6.6 glucose-inhibited division protein A (NCBI) compare
b2330 yfcB -1.5 -2.7 putative adenine-specific methylase (VIMSS) compare
b3636 rpmG -1.5 -3.4 50S ribosomal protein L33 (NCBI) compare
b3863 polA -1.5 -1.6 DNA polymerase I (NCBI) compare
b2939 yqgB -1.4 -2.4 predicted protein (RefSeq) compare
b2784 relA -1.4 -8.7 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b1105 ycfM -1.4 -7.2 predicted outer membrane lipoprotein (NCBI) compare
b1292 sapC -1.4 -2.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b0430 cyoC -1.4 -7.1 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b0431 cyoB -1.4 -10.0 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b2528 iscA -1.4 -1.5 iron-sulfur cluster assembly protein (NCBI) compare
b1859 znuB -1.4 -7.1 high-affinity zinc transporter membrane component (NCBI) compare
b0014 dnaK -1.4 -3.2 molecular chaperone DnaK (NCBI) compare
b3493 pitA -1.4 -7.7 phosphate transporter, low-affinity (NCBI) compare
b1858 znuC -1.4 -5.9 high-affinity zinc transporter ATPase (NCBI) compare
b0088 murD -1.4 -1.0 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b4172 hfq -1.4 -0.9 RNA-binding protein Hfq (NCBI) compare
b1048 mdoG -1.4 -6.7 glucan biosynthesis protein, periplasmic (NCBI) compare
b3743 asnC -1.4 -7.9 DNA-binding transcriptional dual regulator (NCBI) compare
b2276 nuoN -1.3 -5.4 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b0051 ksgA -1.3 -4.8 dimethyladenosine transferase (NCBI) compare
b2822 recC -1.3 -5.7 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4234 yjgA -1.3 -3.5 hypothetical protein (NCBI) compare
b0053 surA -1.3 -6.2 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2340 sixA -1.3 -4.8 phosphohistidine phosphatase (NCBI) compare
b0428 cyoE -1.3 -6.4 protoheme IX farnesyltransferase (NCBI) compare
b3728 pstS -1.3 -4.3 phosphate transporter subunit (NCBI) compare
b3791 rffA -1.3 -6.5 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b1049 mdoH -1.3 -8.6 glucosyltransferase MdoH (NCBI) compare
b1857 yebL -1.3 -6.8 putative adhesin (VIMSS) compare
b3650 spoT -1.3 -5.5 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) compare
b3630 rfaP -1.2 -9.0 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b0432 cyoA -1.2 -8.9 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b4480 hdfR -1.2 -5.7 transcriptional regulator HdfR (NCBI) compare
b3849 trkH -1.2 -7.8 potassium transporter (NCBI) compare
b0949 uup -1.2 -7.3 fused predicted transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4503 yafF -1.2 -1.3 no description compare
b3764 yifE -1.2 -4.8 hypothetical protein (NCBI) compare
b4155 yjeA -1.2 -1.3 putative lysyl-tRNA synthetase (VIMSS) compare
b4414 tff -1.2 -1.5 unknown RNA (NCBI) compare
b3725 pstB -1.2 -1.1 phosphate transporter subunit (NCBI) compare
b0092 ddlB -1.2 -5.5 D-alanylalanine synthetase (NCBI) compare
b3631 rfaG -1.1 -9.6 glucosyltransferase I (NCBI) compare
b0908 aroA -1.1 -7.7 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b2897 ygfY -1.1 -2.5 hypothetical protein (NCBI) compare
b1161 ycgX -1.1 -1.6 hypothetical protein (NCBI) compare
b1865 nudB -1.1 -1.5 dATP pyrophosphohydrolase (NCBI) compare
b2289 lrhA -1.1 -6.3 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) compare
b2281 nuoI -1.1 -2.8 NADH dehydrogenase subunit I (NCBI) compare
b3790 rffC -1.1 -4.9 TDP-fucosamine acetyltransferase (RefSeq) compare
b2285 nuoE -1.1 -2.1 NADH dehydrogenase subunit E (NCBI) compare
b3842 rfaH -1.1 -4.6 transcriptional activator RfaH (NCBI) compare
b2277 nuoM -1.1 -4.6 NADH dehydrogenase subunit M (NCBI) compare
b3463 ftsE -1.1 -0.7 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b1860 ruvB -1.1 -1.2 Holliday junction DNA helicase B (NCBI) compare
b1286 rnb -1.1 -2.0 exoribonuclease II (NCBI) compare
b2278 nuoL -1.0 -6.1 NADH dehydrogenase subunit L (NCBI) compare
b2283 nuoG -1.0 -5.4 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b0623 cspE -1.0 -2.2 cold shock protein E (NCBI) compare
b3198 kdsC -1.0 -3.3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b3706 trmE -1.0 -3.8 tRNA modification GTPase (NCBI) compare
b1658 purR -1.0 -4.8 DNA-binding transcriptional repressor, hypoxanthine-binding (NCBI) compare
b0113 pdhR -1.0 -3.9 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b2318 truA -1.0 -2.9 tRNA pseudouridine synthase A (NCBI) compare
b4416 rybA -1.0 -1.8 unknown RNA (NCBI) compare
b1855 lpxM -1.0 -4.8 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase (NCBI) compare
b2947 gshB -1.0 -3.4 glutathione synthetase (NCBI) compare
b2188 yejM -1.0 -6.2 predicted hydrolase, inner membrane (NCBI) compare
b1709 btuD -1.0 -0.8 vitamin B12-transporter ATPase (NCBI) compare
b2286 nuoC -1.0 -4.0 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b1347 ydaC -1.0 -0.6 Rac prophage; predicted protein (NCBI) compare
b3414 gntY -1.0 -4.6 predicted gluconate transport associated protein (NCBI) compare
b0028 fkpB -1.0 -1.9 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (NCBI) compare
b3860 dsbA -1.0 -6.1 periplasmic protein disulfide isomerase I (NCBI) compare
b3398 yrfF -0.9 -3.3 predicted inner membrane protein (NCBI) compare
b1084 rne -0.9 -4.4 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b3816 corA -0.9 -6.6 magnesium/nickel/cobalt transporter (NCBI) compare
b2168 fruK -0.9 -1.8 1-phosphofructokinase (NCBI) compare
b1497 b1497 -0.9 -0.6 putative enzyme (VIMSS) compare
b2282 nuoH -0.9 -2.9 NADH dehydrogenase subunit H (NCBI) compare
b2938 speA -0.9 -6.4 arginine decarboxylase (NCBI) compare
b1130 phoP -0.9 -2.1 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b0429 cyoD -0.9 -3.9 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b0004 thrC -0.9 -6.7 threonine synthase (NCBI) compare
b3026 qseC -0.9 -3.6 sensory histidine kinase in two-component regulatory system with QseB (NCBI) compare
b1861 ruvA -0.9 -1.3 Holliday junction DNA helicase motor protein (NCBI) compare
b3726 pstA -0.9 -4.8 phosphate transporter subunit (NCBI) compare
b1536 ydeI -0.9 -1.6 hypothetical protein (NCBI) compare
b0720 gltA -0.9 -5.4 citrate synthase (NCBI) compare
b2313 cvpA -0.9 -3.4 membrane protein required for colicin V production (NCBI) compare
b0427 yajR -0.9 -6.3 putative transport protein (VIMSS) compare
b3933 ftsN -0.9 -4.3 essential cell division protein (NCBI) compare
b1285 gmr -0.9 -4.2 modulator of Rnase II stability (NCBI) compare
b4313 fimE -0.8 -5.5 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source Ying_all64 in Escherichia coli BW25113

For carbon source Ying_all64 across organisms