Experiment set57IT038 for Escherichia coli BW25113

Compare to:

Ying_all64 rep B; time point 3

200 most important genes:

  gene name fitness t score description  
b1192 ldcA -8.4 -5.8 L,D-carboxypeptidase A (NCBI) compare
b4388 serB -6.9 -12.4 3-phosphoserine phosphatase (NCBI) compare
b0907 serC -6.7 -11.2 phosphoserine aminotransferase (NCBI) compare
b2913 serA -6.5 -15.1 D-3-phosphoglycerate dehydrogenase (NCBI) compare
b4208 cycA -6.3 -18.5 D-alanine/D-serine/glycine transporter (NCBI) conserved
b0741 pal -5.8 -6.9 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0739 tolA -5.6 -3.9 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1291 sapD -5.6 -3.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2912 ygfA -5.2 -6.2 putative ligase (VIMSS) compare
b0438 clpX -5.1 -12.4 ATP-dependent protease ATP-binding subunit (NCBI) compare
b3792 wzxE -5.1 -6.1 O-antigen translocase (NCBI) compare
b3839 tatC -5.1 -13.6 TatABCE protein translocation system subunit (NCBI) compare
b0740 tolB -5.0 -8.9 translocation protein TolB precursor (NCBI) compare
b0737 tolQ -4.9 -6.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b0738 tolR -4.7 -5.6 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2830 nudH -4.3 -3.0 dinucleoside polyphosphate hydrolase (NCBI) compare
b0957 ompA -4.2 -5.7 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b0049 apaH -4.1 -5.7 diadenosinetetraphosphatase (NCBI) compare
b2576 srmB -4.1 -7.4 ATP-dependent RNA helicase (NCBI) compare
b0439 lon -4.1 -10.1 DNA-binding ATP-dependent protease La (NCBI) compare
b3021 ygiT -4.0 -3.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b0200 gmhB -3.9 -2.7 hypothetical protein (NCBI) compare
b0688 pgm -3.8 -8.4 phosphoglucomutase (NCBI) compare
b0920 ycbC -3.7 -7.2 conserved inner membrane protein (NCBI) compare
b2479 gcvR -3.7 -8.3 transcriptional regulation of gcv operon (VIMSS) compare
b0912 ihfB -3.6 -4.3 integration host factor subunit beta (NCBI) compare
b1712 ihfA -3.5 -2.4 integration host factor subunit alpha (NCBI) compare
b3390 aroK -3.5 -4.4 shikimate kinase I (NCBI) compare
b3916 pfkA -3.3 -5.0 6-phosphofructokinase (NCBI) compare
b3183 obgE -3.2 -3.1 GTPase involved in cell partioning and DNA repair (NCBI) compare
b0726 sucA -3.2 -7.0 alpha-ketoglutarate decarboxylase (NCBI) compare
b1830 prc -3.2 -8.6 carboxy-terminal protease for penicillin-binding protein 3 (NCBI) compare
b3619 rfaD -3.1 -8.4 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1236 galU -3.1 -9.6 glucose-1-phosphate uridylyltransferase (NCBI) compare
b3162 deaD -3.0 -9.1 inducible ATP-independent RNA helicase (VIMSS) compare
b4375 prfC -3.0 -8.8 peptide chain release factor 3 (NCBI) compare
b0678 nagB -3.0 -7.3 glucosamine-6-phosphate deaminase (NCBI) compare
b0222 lpcA -2.9 -4.6 phosphoheptose isomerase (NCBI) compare
b3229 sspA -2.9 -6.1 stringent starvation protein A (NCBI) compare
b0401 brnQ -2.8 -16.4 predicted branched chain amino acid transporter (LIV-II) (NCBI) compare
b0232 yafN -2.8 -1.6 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b0890 ftsK -2.8 -8.9 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b4042 dgkA -2.8 -3.7 diacylglycerol kinase (NCBI) compare
b2699 recA -2.7 -1.9 recombinase A (NCBI) compare
b3838 tatB -2.7 -6.0 sec-independent translocase (NCBI) compare
b2894 xerD -2.7 -1.8 site-specific tyrosine recombinase XerD (NCBI) compare
b2569 lepA -2.6 -6.3 GTP-binding protein LepA (NCBI) compare
b0437 clpP -2.6 -7.9 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b3811 xerC -2.6 -2.5 site-specific tyrosine recombinase XerC (NCBI) compare
b0080 fruR -2.6 -8.0 DNA-binding transcriptional dual regulator (NCBI) compare
b3621 rfaC -2.6 -7.9 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b4676 yoaK -2.6 -1.3 expressed protein (RefSeq) compare
b0632 dacA -2.5 -11.2 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) (NCBI) compare
b2350 yfdG -2.5 -3.9 CPS-53 (KpLE1) prophage; bactoprenol-linked glucose translocase (flippase) (NCBI) compare
b3164 pnp -2.5 -5.7 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b3613 yibP -2.4 -7.9 putative membrane protein (VIMSS) compare
b3052 rfaE -2.4 -7.6 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0677 nagA -2.4 -8.8 N-acetylglucosamine-6-phosphate deacetylase (NCBI) compare
b1293 sapB -2.4 -2.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1677 lpp -2.3 -3.1 murein lipoprotein (NCBI) compare
b2518 ndk -2.3 -5.8 nucleoside diphosphate kinase (NCBI) compare
b2820 recB -2.3 -2.2 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b4414 tff -2.3 -2.5 unknown RNA (NCBI) compare
b0114 aceE -2.3 -2.2 pyruvate dehydrogenase subunit E1 (NCBI) compare
b2937 speB -2.3 -7.8 agmatinase (NCBI) compare
b3620 rfaF -2.2 -7.5 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b0722 sdhD -2.2 -5.6 succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) compare
b2528 iscA -2.2 -4.1 iron-sulfur cluster assembly protein (NCBI) compare
b1361 ydaW -2.2 -1.2 orf, hypothetical protein (VIMSS) compare
b3728 pstS -2.2 -4.8 phosphate transporter subunit (NCBI) compare
b2363 yfdT -2.2 -4.1 CPS-53 (KpLE1) prophage; predicted protein (NCBI) compare
b0720 gltA -2.1 -10.3 citrate synthase (NCBI) compare
b1551 b1551 -2.1 -1.4 orf, hypothetical protein (VIMSS) compare
b2281 nuoI -2.1 -5.8 NADH dehydrogenase subunit I (NCBI) compare
b4239 treC -2.0 -3.4 trehalose-6-P hydrolase (NCBI) compare
b0088 murD -2.0 -1.4 UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) compare
b4155 yjeA -2.0 -1.4 putative lysyl-tRNA synthetase (VIMSS) compare
b2784 relA -2.0 -10.5 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b0053 surA -2.0 -7.0 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2279 nuoK -2.0 -3.8 NADH dehydrogenase subunit K (NCBI) compare
b0721 sdhC -1.9 -7.6 succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) compare
b2277 nuoM -1.9 -8.2 NADH dehydrogenase subunit M (NCBI) compare
b3204 ptsN -1.9 -5.1 sugar-specific enzyme IIA component of PTS (NCBI) compare
b0889 lrp -1.9 -3.6 DNA-binding transcriptional dual regulator, leucine-binding (NCBI) compare
b3290 trkA -1.9 -4.0 potassium transporter peripheral membrane component (NCBI) compare
b1058 yceO -1.9 -1.0 hypothetical protein (NCBI) compare
b4234 yjgA -1.9 -6.2 hypothetical protein (NCBI) compare
b0149 mrcB -1.9 -12.4 penicillin-binding protein 1b (NCBI) compare
b2329 aroC -1.9 -6.9 chorismate synthase (NCBI) compare
b3806 cyaA -1.8 -7.0 adenylate cyclase (NCBI) compare
b4146 yjeK -1.8 -4.6 predicted lysine aminomutase (NCBI) compare
b0724 sdhB -1.8 -6.8 succinate dehydrogenase, FeS subunit (NCBI) compare
b4202 rpsR -1.8 -1.9 30S ribosomal protein S18 (NCBI) compare
b2144 sanA -1.8 -13.0 hypothetical protein (NCBI) compare
b2935 tktA -1.8 -4.0 transketolase 1, thiamin-binding (NCBI) compare
b4481 rffT -1.8 -6.3 4-alpha-L-fucosyltransferase (NCBI) compare
b2276 nuoN -1.8 -5.7 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b3082 ygjM -1.7 -3.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b3844 fre -1.7 -6.3 NAD(P)H-flavin reductase (NCBI) compare
b1545 pinQ -1.7 -0.6 Qin prophage; predicted site-specific recombinase (NCBI) compare
b3500 gor -1.7 -3.2 glutathione reductase (NCBI) compare
b2853 ygeI -1.7 -1.1 hypothetical protein (NCBI) compare
b2282 nuoH -1.7 -5.4 NADH dehydrogenase subunit H (NCBI) compare
b1182 hlyE -1.7 -1.1 hemolysin E (VIMSS) compare
b4458 oxyS -1.7 -2.3 global regulatory RNA (NCBI) compare
b4201 priB -1.7 -2.9 primosomal replication protein N (NCBI) compare
b2652 ileY -1.7 -1.6 tRNA-Ile (NCBI) compare
b2278 nuoL -1.7 -9.5 NADH dehydrogenase subunit L (NCBI) compare
b1105 ycfM -1.6 -7.7 predicted outer membrane lipoprotein (NCBI) compare
b1861 ruvA -1.6 -1.8 Holliday junction DNA helicase motor protein (NCBI) compare
b2285 nuoE -1.6 -3.2 NADH dehydrogenase subunit E (NCBI) compare
b3027 ygiZ -1.6 -1.1 conserved inner membrane protein (NCBI) compare
b3600 mtlD -1.6 -6.1 mannitol-1-phosphate 5-dehydrogenase (NCBI) compare
b1286 rnb -1.6 -3.2 exoribonuclease II (NCBI) compare
b1857 yebL -1.6 -6.6 putative adhesin (VIMSS) compare
b3386 rpe -1.6 -1.1 ribulose-phosphate 3-epimerase (NCBI) compare
b0723 sdhA -1.6 -9.8 succinate dehydrogenase flavoprotein subunit (NCBI) compare
b2897 ygfY -1.6 -4.2 hypothetical protein (NCBI) compare
b2567 rnc -1.6 -1.8 ribonuclease III (NCBI) compare
b3609 secB -1.6 -2.2 export protein SecB (NCBI) compare
b3493 pitA -1.6 -8.3 phosphate transporter, low-affinity (NCBI) compare
b3764 yifE -1.6 -5.4 hypothetical protein (NCBI) compare
b1165 ymgA -1.5 -1.0 hypothetical protein (NCBI) compare
b3863 polA -1.5 -2.0 DNA polymerase I (NCBI) compare
b1290 sapF -1.5 -2.7 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2330 yfcB -1.5 -2.6 putative adenine-specific methylase (VIMSS) compare
b4702 mgtL -1.5 -2.4 regulatory leader peptide for mgtA (NCBI) compare
b0051 ksgA -1.5 -3.9 dimethyladenosine transferase (NCBI) compare
b0623 cspE -1.5 -2.2 cold shock protein E (NCBI) compare
b2290 yfbQ -1.4 -10.0 aspartate aminotransferase (NCBI) compare
b2287 nuoB -1.4 -3.0 NADH dehydrogenase subunit B (NCBI) compare
b1859 znuB -1.4 -7.0 high-affinity zinc transporter membrane component (NCBI) compare
b0908 aroA -1.4 -9.1 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b2284 nuoF -1.4 -4.1 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b0145 dksA -1.4 -2.9 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3741 gidA -1.4 -6.3 glucose-inhibited division protein A (NCBI) compare
b3163 nlpI -1.4 -4.6 hypothetical protein (NCBI) compare
b1572 ydfB -1.4 -2.6 orf, hypothetical protein (VIMSS) compare
b4695 ykgT -1.4 -2.8 no description compare
b1863 ruvC -1.3 -2.4 Holliday junction resolvase (NCBI) compare
b2188 yejM -1.3 -8.3 predicted hydrolase, inner membrane (NCBI) compare
b1049 mdoH -1.3 -8.8 glucosyltransferase MdoH (NCBI) compare
b0658 ybeX -1.3 -1.5 predicteed ion transport (NCBI) compare
b1493 gadB -1.3 -1.2 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b0430 cyoC -1.3 -5.3 cytochrome o ubiquinol oxidase subunit III (NCBI) compare
b1676 pykF -1.3 -5.6 pyruvate kinase (NCBI) compare
b1536 ydeI -1.3 -2.3 hypothetical protein (NCBI) compare
b3198 kdsC -1.3 -4.3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (NCBI) compare
b2283 nuoG -1.3 -6.4 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b2286 nuoC -1.3 -5.2 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b1088 yceD -1.2 -4.5 hypothetical protein (NCBI) compare
b2280 nuoJ -1.2 -5.1 NADH dehydrogenase subunit J (NCBI) compare
b3426 glpD -1.2 -4.6 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b3205 yhbJ -1.2 -5.1 hypothetical protein (NCBI) compare
b3743 asnC -1.2 -7.2 DNA-binding transcriptional dual regulator (NCBI) compare
b3849 trkH -1.2 -8.5 potassium transporter (NCBI) compare
b2620 smpB -1.2 -0.8 SsrA-binding protein (NCBI) compare
b0243 proA -1.2 -7.4 gamma-glutamyl phosphate reductase (NCBI) compare
b3169 nusA -1.2 -4.1 transcription elongation factor NusA (NCBI) compare
b3725 pstB -1.2 -1.1 phosphate transporter subunit (NCBI) compare
b0428 cyoE -1.2 -5.9 protoheme IX farnesyltransferase (NCBI) compare
b3791 rffA -1.2 -5.5 TDP-4-oxo-6-deoxy-D-glucose transaminase (NCBI) compare
b3726 pstA -1.2 -5.6 phosphate transporter subunit (NCBI) compare
b0431 cyoB -1.2 -8.4 cytochrome o ubiquinol oxidase subunit I (NCBI) compare
b0386 proC -1.1 -5.0 pyrroline-5-carboxylate reductase (NCBI) compare
b0432 cyoA -1.1 -7.6 cytochrome o ubiquinol oxidase subunit II (NCBI) compare
b4480 hdfR -1.1 -5.7 transcriptional regulator HdfR (NCBI) compare
b3790 rffC -1.1 -4.5 TDP-fucosamine acetyltransferase (RefSeq) compare
b3636 rpmG -1.1 -1.9 50S ribosomal protein L33 (NCBI) compare
b0429 cyoD -1.1 -4.6 cytochrome o ubiquinol oxidase subunit IV (NCBI) compare
b3706 trmE -1.1 -3.7 tRNA modification GTPase (NCBI) compare
b1048 mdoG -1.1 -5.2 glucan biosynthesis protein, periplasmic (NCBI) compare
b3630 rfaP -1.1 -7.3 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b2808 gcvA -1.1 -3.8 DNA-binding transcriptional dual regulator (NCBI) compare
b0113 pdhR -1.1 -4.9 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b4177 purA -1.1 -1.9 adenylosuccinate synthetase (NCBI) compare
b2318 truA -1.1 -3.6 tRNA pseudouridine synthase A (NCBI) compare
b2289 lrhA -1.1 -6.7 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) compare
b4179 vacB -1.1 -5.3 putative enzyme (VIMSS) compare
b3650 spoT -1.1 -5.2 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) compare
b0729 sucD -1.1 -3.1 succinyl-CoA synthetase subunit alpha (NCBI) compare
b2288 nuoA -1.0 -1.9 NADH dehydrogenase I chain A (VIMSS) compare
b3842 rfaH -1.0 -5.1 transcriptional activator RfaH (NCBI) compare
b2017 yefM -1.0 -1.4 orf, hypothetical protein (VIMSS) compare
b3631 rfaG -1.0 -8.4 glucosyltransferase I (NCBI) compare
b3860 dsbA -1.0 -6.4 periplasmic protein disulfide isomerase I (NCBI) compare
b0028 fkpB -1.0 -2.0 FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) (NCBI) compare
b1347 ydaC -1.0 -0.6 Rac prophage; predicted protein (NCBI) compare
b1506 yneL -1.0 -1.8 predicted transcriptional regulator (NCBI) compare
b0242 proB -1.0 -4.1 gamma-glutamyl kinase (NCBI) compare
b3199 yrbK -1.0 -1.4 hypothetical protein (NCBI) compare
b4685 yrbN -1.0 -2.6 expressed protein (RefSeq) compare
b0683 fur -1.0 -1.9 ferric uptake regulator (NCBI) compare
b1858 znuC -1.0 -4.5 high-affinity zinc transporter ATPase (NCBI) compare
b0142 folK -1.0 -0.8 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b2814 metZ -1.0 -1.9 tRNA-Met (NCBI) compare
b2340 sixA -1.0 -4.1 phosphohistidine phosphatase (NCBI) compare
b1502 ydeQ -1.0 -2.5 predicted fimbrial-like adhesin protein (NCBI) compare
b1025 ycdT -1.0 -1.9 predicted diguanylate cyclase (NCBI) compare
b2822 recC -1.0 -3.6 exonuclease V (RecBCD complex), gamma chain (NCBI) compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source Ying_all64 in Escherichia coli BW25113

For carbon source Ying_all64 across organisms