Experiment set57IT038 for Escherichia coli BW25113

Compare to:

Ying_all64 rep B; time point 3

200 most detrimental genes:

  gene name fitness t score description  
b4552 yrhC +1.3 1.8 no description compare
b4647 mokA +1.2 1.1 no description compare
b1936 intG +1.2 3.0 predicted defective phage integrase (pseudogene) (RefSeq) compare
b4066 yjcF +1.2 1.4 hypothetical protein (NCBI) compare
b4402 yjjY +1.1 2.8 hypothetical protein (NCBI) compare
b1725 yniA +1.0 3.3 predicted phosphotransferase/kinase (NCBI) compare
b1429 tehA +0.9 1.2 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b2642 yfjW +0.8 1.6 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1279 yciS +0.8 1.7 conserved inner membrane protein (NCBI) compare
b1954 dsrA +0.7 2.7 regulatory antisense RNA (NCBI) compare
b4520 ymgF +0.7 2.0 hypothetical protein (NCBI) compare
b0564 appY +0.7 1.2 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b3206 npr +0.7 5.2 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) compare
b4451 ryhB +0.7 2.1 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b1159 mcrA +0.7 1.4 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b1784 yeaH +0.7 5.0 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b1446 ydcY +0.7 2.3 hypothetical protein (NCBI) compare
b1259 yciG +0.6 1.2 orf, hypothetical protein (VIMSS) compare
b1783 yeaG +0.6 4.7 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b1150 ymfR +0.6 1.1 e14 prophage; predicted protein (NCBI) compare
b1595 ynfL +0.6 2.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b1667 ydhR +0.6 1.0 hypothetical protein (NCBI) compare
b1904 yecR +0.5 2.2 hypothetical protein (NCBI) compare
b2953 yggU +0.5 2.0 orf, hypothetical protein (VIMSS) compare
b1188 ycgB +0.5 3.3 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b0968 yccX +0.5 3.6 predicted acylphosphatase (NCBI) compare
b1882 cheY +0.5 0.6 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b1597 asr +0.5 3.0 acid shock protein (VIMSS) compare
b2579 yfiD +0.5 1.6 pyruvate formate lyase subunit (NCBI) compare
b1848 yebG +0.5 1.4 conserved protein regulated by LexA (NCBI) compare
b4441 glmY +0.5 1.5 sRNA activator of glmS mRNA (RefSeq) compare
b2829 ptsP +0.5 4.0 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b1823 cspC +0.5 1.9 stress protein, member of the CspA-family (NCBI) compare
b2114 metG +0.5 1.7 methionyl-tRNA synthetase (NCBI) compare
b4594 ymgJ +0.5 2.1 hypothetical protein (RefSeq) compare
b2605 yfiB +0.5 2.1 predicted outer membrane lipoprotein (NCBI) compare
b1760 ynjH +0.5 3.3 hypothetical protein (NCBI) compare
b4048 yjbM +0.5 1.2 hypothetical protein (NCBI) compare
b1434 ydcN +0.4 1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b4592 yccB +0.4 1.6 hypothetical protein (RefSeq) compare
b2229 b2229 +0.4 3.0 orf, hypothetical protein (VIMSS) compare
b1946 fliN +0.4 1.9 flagellar motor switch protein (NCBI) compare
b2446 yffO +0.4 1.0 CPZ-55 prophage; predicted protein (NCBI) compare
b2536 hcaT +0.4 2.4 predicted 3-phenylpropionic transporter (NCBI) compare
b4701 sokX +0.4 0.7 sok-related sRNA, function unknown (RefSeq) compare
b1607 ydgC +0.4 1.2 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b1348 lar +0.4 1.3 Rac prophage; restriction alleviation protein (NCBI) compare
b1891 flhC +0.4 2.0 DNA-binding transcriptional dual regulator with FlhD (NCBI) compare
b2659 b2659 +0.4 0.9 orf, hypothetical protein (VIMSS) compare
b2096 gatY +0.4 2.6 tagatose-bisphosphate aldolase 1 (VIMSS) compare
b1295 ymjA +0.4 1.1 hypothetical protein (NCBI) compare
b0643 ybeL +0.4 2.2 hypothetical protein (NCBI) compare
b1111 ycfQ +0.4 1.1 orf, hypothetical protein (VIMSS) compare
b2352 yfdI +0.4 0.7 CPS-53 (KpLE1) prophage; predicted inner membrane protein (NCBI) compare
b1868 yecE +0.4 2.2 hypothetical protein (NCBI) compare
b2437 yfeG +0.4 2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1731 cedA +0.4 1.9 cell division modulator (RefSeq) compare
b2768 ygcP +0.4 1.8 predicted anti-terminator regulatory protein (NCBI) compare
b1219 ychN +0.4 2.2 hypothetical protein (NCBI) compare
b1739 osmE +0.4 1.3 DNA-binding transcriptional activator (NCBI) compare
b1075 flgD +0.4 1.9 flagellar basal body rod modification protein D (NCBI) compare
b2259 pmrD +0.4 0.7 polymyxin resistance protein B (VIMSS) compare
b1106 ycfN +0.4 2.4 thiamin kinase (NCBI) compare
b1523 yneG +0.4 1.3 hypothetical protein (NCBI) compare
b1247 oppF +0.4 1.6 oligopeptide transporter subunit (NCBI) compare
b0450 glnK +0.4 1.5 nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB (NCBI) compare
b2755 ygbT +0.4 2.3 hypothetical protein (NCBI) compare
b1148 ymfM +0.4 2.1 e14 prophage; predicted protein (NCBI) compare
b2300 yfcE +0.4 1.9 orf, hypothetical protein (VIMSS) compare
b1281 pyrF +0.4 1.5 orotidine 5'-phosphate decarboxylase (NCBI) compare
b1685 ydiH +0.4 0.8 predicted protein (RefSeq) compare
b2506 yfgI +0.4 0.9 hypothetical protein (NCBI) compare
b3119 tdcR +0.4 0.8 threonine dehydratase operon activator protein (VIMSS) compare
b2499 purM +0.4 2.1 phosphoribosylaminoimidazole synthetase (NCBI) compare
b1591 b1591 +0.4 1.2 putative oxidoreductase component (VIMSS) compare
b1949 fliQ +0.4 1.2 flagellar biosynthesis protein Q (NCBI) compare
b2504 yfgG +0.4 0.6 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b1344 ydaO +0.4 1.4 predicted C32 tRNA thiolase (NCBI) compare
b1582 ynfA +0.3 0.9 hypothetical protein (NCBI) compare
b0714 nei +0.3 2.0 endonuclease VIII/ 5-formyluracil/5-hydroxymethyluracil DNA glycosylase (NCBI) compare
b1539 ydfG +0.3 1.2 L-allo-threonine dehydrogenase, NAD(P)-binding (NCBI) compare
b4461 yfjD +0.3 2.8 predicted inner membrane protein (RefSeq) compare
b1942 fliJ +0.3 0.8 flagellar biosynthesis chaperone (NCBI) compare
b4341 yjiS +0.3 1.3 hypothetical protein (NCBI) compare
b0782 moaB +0.3 1.3 molybdopterin biosynthesis protein B (NCBI) compare
b3074 ygjH +0.3 1.6 hypothetical protein (NCBI) compare
b1450 b1450 +0.3 1.8 orf, hypothetical protein (VIMSS) compare
b4644 ypjI +0.3 2.1 no description compare
b1711 btuC +0.3 1.5 vtamin B12-transporter permease (NCBI) compare
b2448 yffQ +0.3 2.1 CPZ-55 prophage; predicted protein (RefSeq) compare
b0934 ycbM +0.3 1.6 putative transport system permease protein (VIMSS) compare
b2646 ypjF +0.3 1.4 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b1879 flhA +0.3 2.2 flagellar biosynthesis protein A (NCBI) compare
b4293 fecI +0.3 1.3 KpLE2 phage-like element; RNA polymerase, sigma 19 factor (NCBI) compare
b4394 yjjX +0.3 0.9 orf, hypothetical protein (VIMSS) compare
b0803 ybiI +0.3 1.9 hypothetical protein (NCBI) compare
b4413 sokC +0.3 0.8 regulatory antisense RNA (NCBI) compare
b2698 recX +0.3 1.0 RecA regulator RecX (NCBI) compare
b4505 insX +0.3 0.6 predicted IS protein (RefSeq) compare
b4655 ythA +0.3 0.7 expressed protein (RefSeq) compare
b3188 sfsB +0.3 1.7 DNA-binding transcriptional activator of maltose metabolism (NCBI) compare
b1588 ynfF +0.3 1.5 oxidoreductase subunit (RefSeq) compare
b1752 ydjZ +0.3 1.5 conserved inner membrane protein (NCBI) compare
b1422 ydcI +0.3 2.0 putative transcriptional regulator LYSR-type (VIMSS) compare
b3979 thrT +0.3 0.3 tRNA-Thr (NCBI) compare
b1648 b1648 +0.3 0.9 orf, hypothetical protein (VIMSS) compare
b1724 ydiZ +0.3 1.0 hypothetical protein (NCBI) compare
b4353 yjiX +0.3 2.4 hypothetical protein (NCBI) compare
b4410 ecnA +0.3 0.8 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b1583 ynfB +0.3 1.4 hypothetical protein (NCBI) compare
b2637 yfjT +0.3 1.1 CP4-57 prophage; predicted protein (NCBI) compare
b2354 yfdK +0.3 1.7 CPS-53 (KpLE1) prophage; conserved protein (NCBI) compare
b1621 malX +0.3 1.9 fused maltose and glucose-specific PTS enzymes: IIB component -! IIC component (NCBI) compare
b4543 ypaA +0.3 1.4 predicted protein (NCBI) compare
b4055 aphA +0.3 2.4 acid phosphatase/phosphotransferase, class B, non-specific (NCBI) compare
b1465 narV +0.3 0.6 nitrate reductase 2 (NRZ), gamma subunit (NCBI) compare
b1838 pphA +0.3 1.8 protein phosphatase 1 modulates phosphoproteins, signals protein misfolding (VIMSS) compare
b1650 nemA +0.3 1.3 N-ethylmaleimide reductase, FMN-linked (NCBI) compare
b0630 lipB +0.3 0.7 protein of lipoate biosynthesis (VIMSS) compare
b1041 csgB +0.3 2.0 curlin nucleator protein, minor subunit in curli complex (NCBI) compare
b1306 pspC +0.3 1.7 DNA-binding transcriptional activator (NCBI) compare
b1780 yeaD +0.3 1.7 orf, hypothetical protein (VIMSS) compare
b1842 holE +0.3 0.8 DNA polymerase III, theta subunit (NCBI) compare
b0520 ylbF +0.3 1.9 hypothetical protein (NCBI) compare
b4482 yigE +0.3 1.9 hypothetical protein (NCBI) compare
b3484 yhhI +0.3 1.0 predicted transposase (NCBI) compare
b2623 yfjH +0.3 1.7 CP4-57 prophage; predicted protein (NCBI) compare
b4648 ysaC +0.3 1.3 no description compare
b1370 insH-5 +0.3 1.2 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b3181 greA +0.3 1.4 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b0527 ybcI +0.3 1.2 conserved inner membrane protein (NCBI) compare
b0357 yaiN +0.3 1.1 putative alpha helix chain (VIMSS) compare
b2369 evgA +0.3 1.3 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b1172 ymgG +0.3 1.9 conserved protein, UPF0757 family (RefSeq) compare
b1926 fliT +0.3 1.5 predicted chaperone (NCBI) compare
b1939 fliG +0.3 1.0 flagellar motor switch protein G (NCBI) compare
b1083 flgL +0.3 1.2 flagellar hook-associated protein L (NCBI) compare
b3998 nfi +0.3 1.5 endonuclease V (deoxyinosine 3'endoduclease) (VIMSS) compare
b0783 moaC +0.3 1.9 molybdenum cofactor biosynthesis protein C (NCBI) compare
b4243 yjgF +0.3 1.3 orf, hypothetical protein (VIMSS) compare
b2419 yfeK +0.3 0.6 hypothetical protein (NCBI) compare
b1553 ydfP +0.3 1.0 Qin prophage; conserved protein (NCBI) compare
b1360 ydaV +0.3 1.0 Rac prophage; predicted DNA replication protein (NCBI) compare
b1317 ycjU +0.3 1.6 predicted beta-phosphoglucomutase (NCBI) compare
b1619 hdhA +0.3 1.7 7-alpha-hydroxysteroid dehydrogenase (NCBI) compare
b4640 yoeG +0.3 1.3 no description compare
b1278 pgpB +0.3 1.0 phosphatidylglycerophosphatase B (NCBI) compare
b2033 wbbJ +0.3 1.7 predicted acyl transferase (NCBI) compare
b2038 rfbC +0.3 1.8 dTDP-4-deoxyrhamnose-3,5-epimerase (NCBI) compare
b2236 yfaE +0.3 1.0 predicted 2Fe-2S cluster-containing protein (NCBI) compare
b1697 ydiQ +0.3 1.9 hypothetical protein (NCBI) compare
b2817 b2817 +0.3 1.9 putative amidase (VIMSS) compare
b1728 ydjM +0.3 0.8 predicted inner membrane protein regulated by LexA (RefSeq) compare
b4376 osmY +0.3 2.0 periplasmic protein (NCBI) compare
b2911 ssrS +0.3 0.6 6S regulatory RNA (NCBI) compare
b1584 speG +0.3 1.9 spermidine N1-acetyltransferase (NCBI) compare
b1974 yodB +0.3 2.1 putative cytochrome (VIMSS) compare
b3024 ygiW +0.3 1.4 hypothetical protein (NCBI) compare
b2824 ygdB +0.3 0.8 orf, hypothetical protein (VIMSS) compare
b1127 pepT +0.3 1.8 peptidase T (NCBI) compare
b2645 yfjZ +0.3 1.4 CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b1818 manY +0.3 1.0 mannose-specific enzyme IIC component of PTS (NCBI) compare
b1415 aldA +0.3 1.3 Lactaldehyde / glycolaldehyde dehydrogenase aldA (EC 1.2.1.22; EC 1.2.1.21) (from data) compare
b1520 b1520 +0.3 1.6 orf, hypothetical protein (VIMSS) compare
b0158 btuF +0.3 1.5 vitamin B12-transporter protein BtuF (NCBI) compare
b1914 uvrY +0.3 1.7 response regulator (NCBI) compare
b1226 narJ +0.3 1.2 molybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1 (NCBI) compare
b0240 crl +0.3 1.7 DNA-binding transcriptional regulator (NCBI) compare
b1883 cheB +0.3 1.2 chemotaxis-specific methylesterase (NCBI) compare
b1940 fliH +0.3 1.7 flagellar biosynthesis; export of flagellar proteins? (VIMSS) compare
b4373 rimI +0.3 1.1 ribosomal-protein-alanine N-acetyltransferase (NCBI) compare
b2905 gcvT +0.3 1.9 glycine cleavage system aminomethyltransferase T (NCBI) compare
b4456 ryiA +0.3 1.6 regulatory sRNA (NCBI) compare
b1640 ydhH +0.3 1.7 anhydro-N-acetylmuramic acid kinase (NCBI) compare
b1511 ydeV +0.3 1.4 putative kinase (VIMSS) compare
b4511 ybdZ +0.3 1.4 hypothetical protein (NCBI) compare
b3134 agaW +0.3 1.7 N-acetylgalactosamine-specific enzyme IIC component of PTS, fragment (pseudogene) (RefSeq) compare
b1938 fliF +0.3 1.9 flagellar M-ring protein (NCBI) compare
b1948 fliP +0.3 1.8 flagellar biosynthesis protein P (NCBI) compare
b4522 yciX_1 +0.3 0.7 hypothetical protein (NCBI) compare
b0382 yaiB +0.3 1.8 hypothetical protein (NCBI) compare
b1528 ydeA +0.3 1.0 sugar efflux transporter (NCBI) compare
b2092 gatC +0.3 1.7 galactitol-specific enzyme IIC component of PTS (NCBI) compare
b2665 ygaU +0.2 1.8 hypothetical protein (NCBI) compare
b1385 feaB +0.2 1.5 phenylacetaldehyde dehydrogenase (VIMSS) compare
b4457 csrC +0.2 0.9 regulatory RNA (NCBI) compare
b4445 omrB +0.2 1.4 sRNA down regulates OM proteins; positively regulated by OmpR/EnvZ; binds Hfq (RefSeq) compare
b1943 fliK +0.2 1.9 flagellar hook-length control protein (NCBI) compare
b1492 gadC +0.2 1.5 predicted glutamate:gamma-aminobutyric acid antiporter (NCBI) compare
b0802 ybiJ +0.2 1.2 hypothetical protein (NCBI) compare
b0992 yccM +0.2 1.7 predicted 4Fe-4S membrane protein (NCBI) compare
b1526 yneJ +0.2 0.9 predicted DNA-binding transcriptional regulator (NCBI) compare
b1628 rsxB +0.2 1.1 electron transport complex protein RnfB (NCBI) compare
b2661 gabD +0.2 1.7 succinate-semialdehyde dehydrogenase I, NADP-dependent (NCBI) compare
b1923 fliC +0.2 1.6 flagellin (NCBI) compare
b2293 yfbT +0.2 0.9 putative phosphatase (VIMSS) compare
b2666 yqaE +0.2 1.4 predicted membrane protein (NCBI) compare
b4144 yjeI +0.2 1.0 orf, hypothetical protein (VIMSS) compare
b0286 yagT +0.2 1.5 predicted xanthine dehydrogenase, 2Fe-2S subunit (NCBI) compare
b1633 nth +0.2 1.0 DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) (NCBI) compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source Ying_all64 in Escherichia coli BW25113

For carbon source Ying_all64 across organisms