Experiment set57IT037 for Escherichia coli BW25113

Compare to:

Ying_all64 rep A; time point 3

200 most detrimental genes:

  gene name fitness t score description  
b1493 gadB +0.9 1.6 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b1279 yciS +0.9 1.9 conserved inner membrane protein (NCBI) compare
b1725 yniA +0.8 2.6 predicted phosphotransferase/kinase (NCBI) compare
b3027 ygiZ +0.8 0.8 conserved inner membrane protein (NCBI) compare
b1685 ydiH +0.7 2.0 predicted protein (RefSeq) compare
b1231 tyrT +0.7 1.4 tRNA-Tyr (NCBI) compare
b1183 umuD +0.7 1.0 DNA polymerase V, subunit D (NCBI) compare
b4676 yoaK +0.7 0.9 expressed protein (RefSeq) compare
b3504 yhiS +0.7 0.6 hypothetical protein (RefSeq) compare
b1726 yniB +0.6 1.1 predicted inner membrane protein (NCBI) compare
b4647 mokA +0.6 0.6 no description compare
b1358 ydaT +0.6 1.0 Rac prophage; predicted protein (NCBI) compare
b1550 b1550 +0.6 1.8 orf, hypothetical protein (VIMSS) compare
b1667 ydhR +0.6 1.3 hypothetical protein (NCBI) compare
b2659 b2659 +0.6 1.3 orf, hypothetical protein (VIMSS) compare
b1567 intK +0.6 1.5 Qin prophage; predicted protein (RefSeq) compare
b1946 fliN +0.6 2.3 flagellar motor switch protein (NCBI) compare
b1823 cspC +0.6 2.1 stress protein, member of the CspA-family (NCBI) compare
b1841 yobA +0.5 2.0 hypothetical protein (NCBI) compare
b1758 b1758 +0.5 1.3 putative cytochrome oxidase (VIMSS) compare
b0564 appY +0.5 0.9 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b1783 yeaG +0.5 4.7 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b4441 glmY +0.5 1.7 sRNA activator of glmS mRNA (RefSeq) compare
b1954 dsrA +0.5 1.7 regulatory antisense RNA (NCBI) compare
b4522 yciX_1 +0.5 2.2 hypothetical protein (NCBI) compare
b1842 holE +0.5 0.9 DNA polymerase III, theta subunit (NCBI) compare
b2792 yqcC +0.5 3.1 hypothetical protein (NCBI) compare
b2586 yfiM +0.5 2.2 predicted protein (RefSeq) compare
b1642 slyA +0.5 1.3 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b1765 ydjA +0.5 0.8 predicted oxidoreductase (NCBI) compare
b0937 ssuE +0.5 1.6 NAD(P)H-dependent FMN reductase (NCBI) compare
b3206 npr +0.5 3.3 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) compare
b2236 yfaE +0.5 2.8 predicted 2Fe-2S cluster-containing protein (NCBI) compare
b1824 yobF +0.5 1.8 hypothetical protein (NCBI) compare
b1486 ddpB +0.5 2.1 D-ala-D-ala transporter subunit (NCBI) compare
b1784 yeaH +0.5 2.6 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b2258 b2258 +0.5 1.1 putative transport/receptor protein (VIMSS) compare
b1188 ycgB +0.5 3.5 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b4651 yibW +0.4 0.4 no description compare
b1992 cobS +0.4 2.0 cobalamin synthase (NCBI) compare
b0843 ybjH +0.4 1.7 hypothetical protein (NCBI) compare
b1595 ynfL +0.4 1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b1348 lar +0.4 1.1 Rac prophage; restriction alleviation protein (NCBI) compare
b4571 wbbL +0.4 1.6 no description compare
b1773 ydjI +0.4 1.7 predicted aldolase (NCBI) compare
b3101 yqjF +0.4 2.1 orf, hypothetical protein (VIMSS) compare
b2817 b2817 +0.4 3.2 putative amidase (VIMSS) compare
b1608 rstA +0.4 1.7 DNA-binding response regulator in two-component regulatory system with RstB (RefSeq) compare
b4503 yafF +0.4 0.7 no description compare
b4653 yicT +0.4 1.1 no description compare
b2829 ptsP +0.4 3.7 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b3623 rfaK +0.4 1.5 lipopolysaccharide core biosynthesis (NCBI) compare
b0979 appB +0.4 2.7 cytochrome bd-II oxidase, subunit II (NCBI) compare
b3382 yhfY +0.4 2.6 orf, hypothetical protein (VIMSS) compare
b2510 b2510 +0.4 2.0 orf, hypothetical protein (VIMSS) compare
b1921 fliZ +0.4 1.6 orf, hypothetical protein (VIMSS) compare
b1040 csgD +0.4 1.1 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b1429 tehA +0.4 0.8 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1600 mdtJ +0.4 1.3 multidrug efflux system transporter (NCBI) compare
b3890 yiiF +0.4 1.8 orf, hypothetical protein (VIMSS) compare
b1939 fliG +0.4 1.6 flagellar motor switch protein G (NCBI) compare
b2229 b2229 +0.4 1.9 orf, hypothetical protein (VIMSS) compare
b0542 renD +0.3 1.3 orf, hypothetical protein (VIMSS) compare
b2809 b2809 +0.3 1.3 orf, hypothetical protein (VIMSS) compare
b1696 ydiP +0.3 1.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b1882 cheY +0.3 0.4 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b1159 mcrA +0.3 0.8 e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) compare
b0789 ybhO +0.3 2.2 cardiolipin synthase 2 (NCBI) compare
b0850 ybjC +0.3 1.7 predicted inner membrane protein (NCBI) compare
b0624 crcB +0.3 2.3 camphor resistance protein CrcB (NCBI) compare
b1531 marA +0.3 1.1 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b1013 ycdC +0.3 1.7 predicted DNA-binding transcriptional regulator (NCBI) compare
b1951 rcsA +0.3 0.8 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b4675 yoaJ +0.3 1.6 expressed protein (RefSeq) compare
b0404 yajB +0.3 1.3 hypothetical protein (NCBI) compare
b1415 aldA +0.3 2.4 Lactaldehyde / glycolaldehyde dehydrogenase aldA (EC 1.2.1.22; EC 1.2.1.21) (from data) compare
b1259 yciG +0.3 1.2 orf, hypothetical protein (VIMSS) compare
b2634 yfjR +0.3 2.2 CP4-57 prophage; predicted DNA-binding transcriptional regulator (NCBI) compare
b3739 atpI +0.3 1.9 membrane-bound ATP synthase, dispensable protein, affects expression of atpB (VIMSS) compare
b4594 ymgJ +0.3 1.4 hypothetical protein (RefSeq) compare
b4493 gapC +0.3 1.7 no description compare
b1723 pfkB +0.3 2.1 6-phosphofructokinase II; suppressor of pfkA (VIMSS) compare
b4413 sokC +0.3 0.8 regulatory antisense RNA (NCBI) compare
b2646 ypjF +0.3 1.4 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b4158 yjeO +0.3 1.5 conserved inner membrane protein (NCBI) compare
b0643 ybeL +0.3 2.0 hypothetical protein (NCBI) compare
b3973 birA +0.3 0.8 biotin--protein ligase (NCBI) compare
b2910 zapA +0.3 1.2 protein that localizes to the cytokinetic ring (NCBI) compare
b2186 yejK +0.3 2.6 nucleoid-associated protein NdpA (NCBI) compare
b4660 yhiL +0.3 0.2 no description compare
b2445 yffN +0.3 1.5 CPZ-55 prophage; predicted protein (RefSeq) compare
b1607 ydgC +0.3 0.8 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b1940 fliH +0.3 1.8 flagellar biosynthesis; export of flagellar proteins? (VIMSS) compare
b0784 moaD +0.3 1.3 molybdopterin synthase, small subunit (NCBI) compare
b2005 yeeV +0.3 2.0 CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system (NCBI) compare
b0803 ybiI +0.3 1.2 hypothetical protein (NCBI) compare
b2327 yfcA +0.3 2.2 conserved inner membrane protein (NCBI) compare
b1427 rimL +0.3 1.1 ribosomal-protein-L7/L12-serine acetyltransferase (NCBI) compare
b0622 crcA +0.3 2.1 palmitoyl transferase for Lipid A (NCBI) compare
b4012 yjaB +0.3 1.8 predicted acetyltransferase (NCBI) compare
b0393 rdgC +0.3 2.1 recombination associated protein (NCBI) compare
b1067 yceH +0.3 1.3 hypothetical protein (NCBI) compare
b4552 yrhC +0.3 0.5 no description compare
b2719 hycG +0.3 2.2 hydrogenase 3 and formate hydrogenase complex, HycG subunit (NCBI) compare
b4609 ryfD +0.3 1.2 Novel sRNA, function unknown (RefSeq) compare
b3134 agaW +0.3 1.4 N-acetylgalactosamine-specific enzyme IIC component of PTS, fragment (pseudogene) (RefSeq) compare
b4408 csrB +0.3 1.3 CsrA-binding sRNA, antagonizing CsrA regulation (NCBI) compare
b3243 aaeR +0.3 1.6 predicted DNA-binding transcriptional regulator, efflux system (NCBI) compare
b4614 sokA +0.3 0.8 no description compare
b3280 yrdB +0.3 1.1 hypothetical protein (NCBI) compare
b1010 ycdK +0.3 1.1 hypothetical protein (NCBI) compare
b2189 proL +0.3 0.9 tRNA-Pro (NCBI) compare
b2929 yggD +0.3 1.3 predicted DNA-binding transcriptional regulator (NCBI) compare
b1613 manA +0.3 1.0 mannose-6-phosphate isomerase (VIMSS) compare
b3119 tdcR +0.3 1.0 threonine dehydratase operon activator protein (VIMSS) compare
b1971 yedY +0.3 1.5 hypothetical protein (NCBI) compare
b4416 rybA +0.3 0.7 unknown RNA (NCBI) compare
b4644 ypjI +0.3 1.6 no description compare
b1931 yedK +0.3 1.2 hypothetical protein (NCBI) compare
b0108 ppdD +0.3 1.7 predicted major pilin subunit (NCBI) compare
b1244 oppB +0.3 2.0 oligopeptide permease ABC transporter membrane protein (NCBI) compare
b1540 ydfH +0.3 0.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b2446 yffO +0.3 0.9 CPZ-55 prophage; predicted protein (NCBI) compare
b0147 yadP +0.3 1.9 orf, hypothetical protein (VIMSS) compare
b2642 yfjW +0.3 0.4 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1584 speG +0.3 2.0 spermidine N1-acetyltransferase (NCBI) compare
b4631 ykgQ +0.3 0.8 no description compare
b1754 b1754 +0.2 0.9 orf, hypothetical protein (VIMSS) compare
b2637 yfjT +0.2 1.2 CP4-57 prophage; predicted protein (NCBI) compare
b1482 osmC +0.2 0.6 osmotically inducible, stress-inducible membrane protein (NCBI) compare
b1688 ydiK +0.2 1.4 predicted inner membrane protein (NCBI) compare
b2038 rfbC +0.2 1.8 dTDP-4-deoxyrhamnose-3,5-epimerase (NCBI) compare
b2168 fruK +0.2 0.5 1-phosphofructokinase (NCBI) compare
b2794 yqcD +0.2 1.9 hypothetical protein (NCBI) compare
b1900 araG +0.2 1.2 fused L-arabinose transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b0783 moaC +0.2 1.6 molybdenum cofactor biosynthesis protein C (NCBI) compare
b2447 yffP +0.2 1.1 CPZ-55 prophage; predicted protein (NCBI) compare
b4630 ykgP +0.2 0.9 no description compare
b1648 b1648 +0.2 0.7 orf, hypothetical protein (VIMSS) compare
b1862 yebB +0.2 1.2 orf, hypothetical protein (VIMSS) compare
b1266 yciV +0.2 1.1 hypothetical protein (NCBI) compare
b3048 yqiI +0.2 1.8 hypothetical protein (NCBI) compare
b1220 ychO +0.2 1.5 predicted invasin (RefSeq) compare
b2432 yfeY +0.2 1.1 hypothetical protein (NCBI) compare
b2536 hcaT +0.2 2.0 predicted 3-phenylpropionic transporter (NCBI) compare
b1521 uxaB +0.2 1.8 tagaturonate reductase (NCBI) compare
b1605 ydgI +0.2 1.4 predicted arginine/ornithine antiporter transporter (NCBI) compare
b2904 gcvH +0.2 1.0 glycine cleavage system protein H (NCBI) compare
b3582 sgbU +0.2 1.3 probable 3-hexulose-6-phosphate isomerase (VIMSS) compare
b1028 ymdE +0.2 1.1 orf, hypothetical protein (VIMSS) compare
b4482 yigE +0.2 1.5 hypothetical protein (NCBI) compare
b4589 ylcI +0.2 0.8 hypothetical protein (RefSeq) compare
b2577 yfiE +0.2 1.5 putative transcriptional regulator LYSR-type (VIMSS) compare
b4269 yjgB +0.2 1.6 putative oxidoreductase (VIMSS) compare
b1724 ydiZ +0.2 1.0 hypothetical protein (NCBI) compare
b1976 b1976 +0.2 0.9 orf, hypothetical protein (VIMSS) compare
b1742 b1742 +0.2 1.2 orf, hypothetical protein (VIMSS) compare
b2903 gcvP +0.2 2.1 glycine dehydrogenase (NCBI) compare
b1450 b1450 +0.2 1.1 orf, hypothetical protein (VIMSS) compare
b0041 fixA +0.2 1.7 probable flavoprotein subunit, carnitine metabolism (VIMSS) compare
b1829 htpX +0.2 1.0 heat shock protein HtpX (NCBI) compare
b0675 nagD +0.2 1.9 UMP phosphatase (NCBI) compare
b1246 oppD +0.2 1.4 oligopeptide transporter ATP-binding component (NCBI) compare
b4543 ypaA +0.2 1.4 predicted protein (NCBI) compare
b2758 ygcJ +0.2 1.7 hypothetical protein (NCBI) compare
b1194 ycgR +0.2 1.0 protein involved in flagellar function (NCBI) compare
b1441 ydcT +0.2 1.4 predicted spermidine/putrescine transporter subunit (NCBI) compare
b2538 hcaE +0.2 1.1 3-phenylpropionate dioxygenase, large (alpha) subunit (NCBI) compare
b4548 ypjJ +0.2 1.3 hypothetical protein (NCBI) compare
b3293 yhdN +0.2 1.5 hypothetical protein (NCBI) compare
b2040 rfbD +0.2 1.8 dTDP-4-dehydrorhamnose reductase subunit, NAD(P)-binding, of dTDP-L-rhamnose synthase (NCBI) compare
b1243 oppA +0.2 1.4 oligopeptide transporter subunit (NCBI) compare
b2326 yfcM +0.2 1.4 hypothetical protein (NCBI) compare
b2319 usg +0.2 1.2 hypothetical protein (NCBI) compare
b1916 sdiA +0.2 1.8 DNA-binding transcriptional activator (NCBI) compare
b3049 glgS +0.2 1.5 glycogen synthesis protein GlgS (NCBI) compare
b1526 yneJ +0.2 1.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b2580 ung +0.2 1.8 uracil-DNA glycosylase (NCBI) compare
b2458 eutI +0.2 1.4 predicted phosphotransacetylase subunit (NCBI) compare
b2246 b2246 +0.2 0.9 putative transport protein (VIMSS) compare
b4409 blr +0.2 1.4 beta-lactam resistance membrane protein (NCBI) compare
b4076 nrfG +0.2 1.5 heme lyase (NrfEFG) for insertion of heme into c552, subunit NrfG (NCBI) compare
b1565 ydfV +0.2 1.0 Qin prophage; predicted protein (NCBI) compare
b3512 GadE +0.2 1.1 acid-responsive regulator of gadA and gadBC (Katherine Huang) compare
b0567 ybcH +0.2 1.6 hypothetical protein (NCBI) compare
b0367 tauC +0.2 1.0 taurine transporter subunit (NCBI) compare
b1621 malX +0.2 1.3 fused maltose and glucose-specific PTS enzymes: IIB component -! IIC component (NCBI) compare
b2676 nrdF +0.2 1.5 ribonucleotide-diphosphate reductase beta subunit (NCBI) compare
b0388 aroL +0.2 1.1 shikimate kinase II (NCBI) compare
b2098 yegT +0.2 1.6 predicted nucleoside transporter (NCBI) compare
b3927 glpF +0.2 1.8 glycerol facilitator (NCBI) compare
b0550 rusA +0.2 0.9 DLP12 prophage; endonuclease RUS (NCBI) compare
b1038 csgF +0.2 1.1 predicted transport protein (NCBI) compare
b4314 fimA +0.2 1.6 major type 1 subunit fimbrin (pilin) (NCBI) compare
b1281 pyrF +0.2 1.2 orotidine 5'-phosphate decarboxylase (NCBI) compare
b1920 fliY +0.2 0.9 cystine transporter subunit (NCBI) compare
b2252 ais +0.2 1.3 hypothetical protein (NCBI) compare
b4330 yjiH +0.2 1.7 orf, hypothetical protein (VIMSS) compare
b0806 ybiM +0.2 0.9 orf, hypothetical protein (VIMSS) compare
b3658 selC +0.2 1.1 tRNA-Sec (NCBI) compare


Specific Phenotypes

For 3 genes in this experiment

For carbon source Ying_all64 in Escherichia coli BW25113

For carbon source Ying_all64 across organisms