Experiment set57IT035 for Escherichia coli BW25113

Compare to:

Ying_Others16 rep B; time point 2

200 most important genes:

  gene name fitness t score description  
b2279 nuoK -5.5 -2.6 NADH dehydrogenase subunit K (NCBI) compare
b1279 yciS -5.0 -1.2 conserved inner membrane protein (NCBI) compare
b1103 ycfF -4.4 -1.5 orf, hypothetical protein (VIMSS) compare
b1291 sapD -4.4 -2.6 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2168 fruK -4.4 -1.8 1-phosphofructokinase (NCBI) compare
b1261 trpB -4.0 -2.0 tryptophan synthase subunit beta (NCBI) compare
b1882 cheY -3.8 -0.9 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b0142 folK -3.7 -0.9 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b0741 pal -3.5 -5.0 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b0739 tolA -3.5 -5.8 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1361 ydaW -3.2 -0.8 orf, hypothetical protein (VIMSS) compare
b0049 apaH -3.2 -4.1 diadenosinetetraphosphatase (NCBI) compare
b0678 nagB -3.2 -4.2 glucosamine-6-phosphate deaminase (NCBI) compare
b0726 sucA -2.9 -5.5 alpha-ketoglutarate decarboxylase (NCBI) compare
b0738 tolR -2.9 -4.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b3979 thrT -2.8 -0.7 tRNA-Thr (NCBI) compare
b0247 ykfG -2.8 -1.3 CP4-6 prophage; predicted DNA repair protein (NCBI) compare
b1260 trpA -2.8 -2.6 tryptophan synthase subunit alpha (NCBI) compare
b2913 serA -2.7 -5.5 D-3-phosphoglycerate dehydrogenase (NCBI) compare
b4503 yafF -2.6 -0.9 no description compare
b3781 trxA -2.6 -4.4 thioredoxin 1 (VIMSS) compare
b2567 rnc -2.6 -1.4 ribonuclease III (NCBI) compare
b0073 leuB -2.5 -6.1 3-isopropylmalate dehydrogenase (VIMSS) compare
b4388 serB -2.5 -5.7 3-phosphoserine phosphatase (NCBI) compare
b0243 proA -2.5 -6.4 gamma-glutamyl phosphate reductase (NCBI) compare
b0438 clpX -2.5 -5.9 ATP-dependent protease ATP-binding subunit (NCBI) compare
b2020 hisD -2.5 -6.2 histidinol dehydrogenase (NCBI) compare
b0200 gmhB -2.4 -2.1 hypothetical protein (NCBI) compare
b2024 hisA -2.4 -2.0 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) compare
b3636 rpmG -2.4 -1.6 50S ribosomal protein L33 (NCBI) compare
b3281 aroE -2.3 -8.9 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b0145 dksA -2.3 -3.1 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b3771 ilvD -2.3 -8.3 dihydroxy-acid dehydratase (NCBI) compare
b3770 ilvE -2.3 -8.2 branched-chain amino acid aminotransferase (NCBI) compare
b0522 purK -2.3 -5.2 phosphoribosylaminoimidazole carboxylase (NCBI) compare
b0564 appY -2.3 -0.7 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b2026 hisI -2.2 -4.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) compare
b1259 yciG -2.2 -1.8 orf, hypothetical protein (VIMSS) compare
b4006 purH -2.2 -7.4 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) compare
b0232 yafN -2.2 -0.8 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b0242 proB -2.2 -4.3 gamma-glutamyl kinase (NCBI) compare
b3772 ilvA -2.2 -7.6 threonine dehydratase (NCBI) compare
b3389 aroB -2.2 -6.5 3-dehydroquinate synthase (NCBI) compare
b3728 pstS -2.2 -3.3 phosphate transporter subunit (NCBI) compare
b2025 hisF -2.1 -3.2 imidazole glycerol phosphate synthase subunit HisF (NCBI) compare
b3774 ilvC -2.1 -7.9 ketol-acid reductoisomerase (NCBI) compare
b2023 hisH -2.1 -3.3 imidazole glycerol phosphate synthase subunit HisH (NCBI) compare
b0003 thrB -2.0 -5.4 homoserine kinase (NCBI) compare
b4529 ydbJ -2.0 -0.9 hypothetical protein (NCBI) compare
b2021 hisC -2.0 -3.7 histidinol-phosphate aminotransferase (NCBI) compare
b4676 yoaK -2.0 -0.6 expressed protein (RefSeq) compare
b2284 nuoF -1.9 -3.3 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b1292 sapC -1.9 -1.8 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2414 cysK -1.9 -6.5 cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) compare
b0072 leuC -1.9 -6.5 isopropylmalate isomerase large subunit (NCBI) compare
b1480 sra -1.9 -1.1 30S ribosomal subunit protein S22 (NCBI) compare
b3811 xerC -1.9 -1.3 site-specific tyrosine recombinase XerC (NCBI) compare
b1476 fdnI -1.9 -0.9 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b0908 aroA -1.9 -5.0 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b1784 yeaH -1.9 -5.0 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b2846 yqeH -1.9 -0.8 orf, hypothetical protein (VIMSS) compare
b4410 ecnA -1.9 -1.2 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b1188 ycgB -1.8 -4.6 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b0907 serC -1.8 -5.7 phosphoserine aminotransferase (NCBI) compare
b1160 elbA -1.8 -0.8 hypothetical protein (NCBI) compare
b0002 thrA -1.8 -6.5 bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) compare
b2022 hisB -1.8 -5.2 imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) compare
b2838 lysA -1.8 -6.1 diaminopimelate decarboxylase, PLP-binding (NCBI) compare
b0439 lon -1.8 -3.7 DNA-binding ATP-dependent protease La (NCBI) compare
b1860 ruvB -1.8 -0.9 Holliday junction DNA helicase B (NCBI) compare
b3960 argH -1.7 -5.9 argininosuccinate lyase (NCBI) compare
b1837 yebW -1.7 -1.5 orf, hypothetical protein (VIMSS) compare
b1192 ldcA -1.7 -3.2 L,D-carboxypeptidase A (NCBI) compare
b3642 pyrE -1.7 -3.4 orotate phosphoribosyltransferase (NCBI) compare
b0004 thrC -1.7 -4.5 threonine synthase (NCBI) compare
b2894 xerD -1.7 -0.9 site-specific tyrosine recombinase XerD (NCBI) compare
b4013 metA -1.7 -2.6 homoserine O-succinyltransferase (NCBI) compare
b2479 gcvR -1.7 -3.6 transcriptional regulation of gcv operon (VIMSS) compare
b1129 phoQ -1.7 -1.1 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b2329 aroC -1.6 -3.2 chorismate synthase (NCBI) compare
b1693 aroD -1.6 -5.0 3-dehydroquinate dehydratase (NCBI) compare
b2188 yejM -1.6 -6.1 predicted hydrolase, inner membrane (NCBI) compare
b4005 purD -1.6 -5.8 phosphoribosylamine--glycine ligase (NCBI) compare
b2312 purF -1.6 -3.4 amidophosphoribosyltransferase (NCBI) compare
b0071 leuD -1.6 -4.4 isopropylmalate isomerase small subunit (NCBI) compare
b0730 mngR -1.6 -2.1 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b1951 rcsA -1.6 -1.1 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b0523 purE -1.6 -2.9 phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) compare
b3426 glpD -1.6 -4.1 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b2784 relA -1.6 -5.4 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b3870 glnA -1.6 -2.7 glutamine synthetase (NCBI) compare
b2051 wcaH -1.6 -1.5 GDP-mannose mannosyl hydrolase (VIMSS) compare
b2600 tyrA -1.5 -3.4 fused chorismate mutase T/prephenate dehydrogenase (NCBI) compare
b1783 yeaG -1.5 -5.1 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b3773 ilvY -1.5 -5.5 DNA-binding transcriptional dual regulator (NCBI) compare
b3941 metF -1.5 -5.2 5,10-methylenetetrahydrofolate reductase (NCBI) compare
b2278 nuoL -1.4 -4.9 NADH dehydrogenase subunit L (NCBI) compare
b2557 purL -1.4 -5.2 phosphoribosylformylglycinamidine synthase (NCBI) compare
b1426 ydcH -1.4 -1.2 orf, hypothetical protein (VIMSS) compare
b1506 yneL -1.4 -1.5 predicted transcriptional regulator (NCBI) compare
b0641 rlpB -1.4 -2.1 minor lipoprotein (NCBI) compare
b0074 leuA -1.4 -4.6 2-isopropylmalate synthase (NCBI) compare
b2019 hisG -1.4 -3.8 ATP phosphoribosyltransferase (NCBI) compare
b2504 yfgG -1.4 -1.5 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b1058 yceO -1.3 -0.4 hypothetical protein (NCBI) compare
b1305 pspB -1.3 -1.7 phage shock protein B (NCBI) compare
b1281 pyrF -1.3 -3.2 orotidine 5'-phosphate decarboxylase (NCBI) compare
b1762 b1762 -1.3 -1.6 orf, hypothetical protein (VIMSS) compare
b2699 recA -1.3 -1.4 recombinase A (NCBI) compare
b2340 sixA -1.3 -1.5 phosphohistidine phosphatase (NCBI) compare
b1231 tyrT -1.3 -0.7 tRNA-Tyr (NCBI) compare
b0440 hupB -1.3 -2.9 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b0560 nohB -1.3 -1.1 DLP12 prophage; DNA packaging protein (NCBI) compare
b1084 rne -1.3 -3.3 fused ribonucleaseE: endoribonuclease/RNA-binding protein/RNA degradosome binding protein (NCBI) compare
b4603 rseX -1.3 -0.5 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b2287 nuoB -1.3 -2.0 NADH dehydrogenase subunit B (NCBI) compare
b0890 ftsK -1.2 -4.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b2839 lysR -1.2 -2.8 DNA-binding transcriptional dual regulator (NCBI) compare
b0737 tolQ -1.2 -1.8 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b1370 insH-5 -1.2 -1.6 Rac prophage; IS5 transposase and trans-activator (NCBI) compare
b1062 pyrC -1.2 -4.0 dihydroorotase (NCBI) compare
b1572 ydfB -1.2 -1.1 orf, hypothetical protein (VIMSS) compare
b1262 trpC -1.2 -4.3 N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) compare
b3839 tatC -1.2 -3.9 TatABCE protein translocation system subunit (NCBI) compare
b0460 hha -1.2 -2.5 modulator of gene expression, with H-NS (NCBI) compare
b2646 ypjF -1.2 -1.3 CP4-57 prophage; toxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b4239 treC -1.2 -1.9 trehalose-6-P hydrolase (NCBI) compare
b1408 b1408 -1.2 -1.9 probable enzyme (VIMSS) compare
b4509 ylcG -1.2 -1.2 DLP12 prophage; predicted protein (NCBI) compare
b3203 yhbH -1.1 -3.2 predicted ribosome-associated, sigma 54 modulation protein (NCBI) compare
b2929 yggD -1.1 -2.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b0437 clpP -1.1 -2.4 ATP-dependent Clp protease proteolytic subunit (NCBI) compare
b0998 torD -1.1 -0.9 chaperone protein TorD (NCBI) compare
b1753 ynjA -1.1 -0.9 hypothetical protein (NCBI) compare
b2288 nuoA -1.1 -1.7 NADH dehydrogenase I chain A (VIMSS) compare
b0542 renD -1.1 -1.5 orf, hypothetical protein (VIMSS) compare
b4647 mokA -1.1 -0.5 no description compare
b4545 ypdJ -1.1 -1.0 no description compare
b4435 isrC -1.1 -1.2 unknown RNA (NCBI) compare
b3290 trkA -1.1 -2.5 potassium transporter peripheral membrane component (NCBI) compare
b3204 ptsN -1.1 -2.5 sugar-specific enzyme IIA component of PTS (NCBI) compare
b2428 yfeU -1.1 -2.9 N-acetylmuramic acid-6-phosphate etherase (NCBI) compare
b2499 purM -1.1 -2.4 phosphoribosylaminoimidazole synthetase (NCBI) compare
b1545 pinQ -1.1 -0.2 Qin prophage; predicted site-specific recombinase (NCBI) compare
b1383 ydbL -1.1 -1.5 orf, hypothetical protein (VIMSS) compare
b2912 ygfA -1.1 -1.5 putative ligase (VIMSS) compare
b2532 yfhQ -1.1 -1.7 predicted methyltransferase (NCBI) compare
b2259 pmrD -1.1 -0.7 polymyxin resistance protein B (VIMSS) compare
b4593 ymgI -1.1 -0.6 hypothetical protein (RefSeq) compare
b2939 yqgB -1.1 -1.0 predicted protein (RefSeq) compare
b2286 nuoC -1.1 -2.4 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b1836 yebV -1.1 -2.3 orf, hypothetical protein (VIMSS) compare
b1551 b1551 -1.1 -0.5 orf, hypothetical protein (VIMSS) compare
b4177 purA -1.1 -0.7 adenylosuccinate synthetase (NCBI) compare
b1358 ydaT -1.1 -0.7 Rac prophage; predicted protein (NCBI) compare
b2444 yffM -1.0 -1.5 CPZ-55 prophage; predicted protein (NCBI) compare
b2763 cysI -1.0 -3.6 sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) compare
b1485 ddpC -1.0 -2.0 D-ala-D-ala transporter subunit (NCBI) compare
b1712 ihfA -1.0 -1.3 integration host factor subunit alpha (NCBI) compare
b4458 oxyS -1.0 -0.8 global regulatory RNA (NCBI) compare
b1853 yebK -1.0 -1.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b0806 ybiM -1.0 -1.2 orf, hypothetical protein (VIMSS) compare
b1789 yeaL -1.0 -2.0 conserved inner membrane protein (NCBI) compare
b2104 thiM -1.0 -2.0 hydroxyethylthiazole kinase (NCBI) compare
b0080 fruR -1.0 -2.6 DNA-binding transcriptional dual regulator (NCBI) compare
b3129 sohA -1.0 -1.9 predicted regulator (NCBI) compare
b3806 cyaA -1.0 -3.2 adenylate cyclase (NCBI) compare
b0580 ybdJ -1.0 -1.0 predicted inner membrane protein (NCBI) compare
b1595 ynfL -1.0 -1.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b2044 wcaL -1.0 -1.8 predicted glycosyl transferase (NCBI) compare
b3236 mdh -1.0 -3.9 malate dehydrogenase (NCBI) compare
b1235 rssB -1.0 -3.0 response regulator of RpoS (NCBI) compare
b4685 yrbN -1.0 -1.1 expressed protein (RefSeq) compare
b2283 nuoG -1.0 -2.9 NADH:ubiquinone oxidoreductase, chain G (RefSeq) compare
b1676 pykF -0.9 -2.4 pyruvate kinase (NCBI) compare
b1976 b1976 -0.9 -1.8 orf, hypothetical protein (VIMSS) compare
b0113 pdhR -0.9 -2.9 transcriptional regulator of pyruvate dehydrogenase complex (NCBI) compare
b3935 priA -0.9 -1.6 primosome assembly protein PriA (NCBI) compare
b1238 tdk -0.9 -3.0 thymidine kinase (NCBI) compare
b1556 b1556 -0.9 -1.0 orf, hypothetical protein (VIMSS) compare
b4214 cysQ -0.9 -4.4 PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) compare
b0843 ybjH -0.9 -0.9 hypothetical protein (NCBI) compare
b4557 yidD -0.9 -1.8 hypothetical protein (NCBI) compare
b3939 metB -0.9 -3.9 cystathionine gamma-synthase (NCBI) compare
b0817 mntR -0.9 -1.8 DNA-binding transcriptional regulator of mntH (NCBI) compare
b0386 proC -0.9 -2.0 pyrroline-5-carboxylate reductase (NCBI) compare
b2599 pheA -0.9 -2.5 fused chorismate mutase P/prephenate dehydratase (NCBI) compare
b3261 fis -0.9 -1.5 DNA-binding protein Fis (NCBI) compare
b1524 yneH -0.9 -0.6 predicted glutaminase (NCBI) compare
b4679 yohP -0.9 -1.3 expressed protein (RefSeq) compare
b2289 lrhA -0.9 -3.6 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) compare
b0658 ybeX -0.9 -0.6 predicteed ion transport (NCBI) compare
b1096 pabC -0.9 -2.8 4-amino-4-deoxychorismate lyase (NCBI) compare
b4598 yncL -0.9 -1.1 hypothetical protein (RefSeq) compare
b1176 minC -0.9 -1.6 septum formation inhibitor (NCBI) compare
b3008 metC -0.9 -4.1 cystathionine beta-lyase (NCBI) compare
b4451 ryhB -0.9 -0.8 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b2807 ygdD -0.9 -1.6 conserved inner membrane protein (NCBI) compare
b0858 ybjO -0.9 -1.0 predicted inner membrane protein (NCBI) compare
b3623 rfaK -0.9 -1.3 lipopolysaccharide core biosynthesis (NCBI) compare


Specific Phenotypes

For 20 genes in this experiment

For carbon source Ying_Others16 in Escherichia coli BW25113

For carbon source Ying_Others16 across organisms