Experiment set57IT022 for Escherichia coli BW25113

Compare to:

Ying_AminoAcid20 rep A; time point 2

200 most detrimental genes:

  gene name fitness t score description  
b3261 fis +2.1 7.6 DNA-binding protein Fis (NCBI) compare
b3229 sspA +1.2 6.8 stringent starvation protein A (NCBI) compare
b1831 proQ +1.2 5.2 putative solute/DNA competence effector (NCBI) compare
b1038 csgF +1.2 4.1 predicted transport protein (NCBI) compare
b1823 cspC +1.2 2.7 stress protein, member of the CspA-family (NCBI) compare
b3753 rbsR +1.2 10.2 DNA-binding transcriptional repressor of ribose metabolism (NCBI) compare
b3341 rpsG +1.1 1.9 30S ribosomal protein S7 (NCBI) compare
b0014 dnaK +1.1 3.4 molecular chaperone DnaK (NCBI) compare
b1422 ydcI +1.1 7.2 putative transcriptional regulator LYSR-type (VIMSS) compare
b1070 flgN +1.0 2.9 export chaperone for FlgK and FlgL (NCBI) compare
b1095 fabF +1.0 7.5 3-oxoacyl-(acyl carrier protein) synthase (NCBI) compare
b1824 yobF +0.9 5.0 hypothetical protein (NCBI) compare
b0382 yaiB +0.9 6.1 hypothetical protein (NCBI) compare
b3260 dusB +0.8 2.7 tRNA-dihydrouridine synthase B (NCBI) compare
b0240 crl +0.8 6.0 DNA-binding transcriptional regulator (NCBI) compare
b1822 rrmA +0.8 2.5 23S rRNA m1G745 methyltransferase (NCBI) compare
b1429 tehA +0.8 1.2 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b1236 galU +0.8 5.0 glucose-1-phosphate uridylyltransferase (NCBI) compare
b1627 rsxA +0.7 3.8 Na(+)-translocating NADH-quinone reductase subunit E (NCBI) compare
b3752 rbsK +0.7 4.9 ribokinase (NCBI) compare
b2259 pmrD +0.7 1.4 polymyxin resistance protein B (VIMSS) compare
b4529 ydbJ +0.7 1.4 hypothetical protein (NCBI) compare
b1082 flgK +0.7 5.0 flagellar hook-associated protein K (NCBI) compare
b3755 yieP +0.7 5.5 predicted transcriptional regulator (NCBI) compare
b1493 gadB +0.7 1.0 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b2659 b2659 +0.7 1.5 orf, hypothetical protein (VIMSS) compare
b1465 narV +0.7 2.4 nitrate reductase 2 (NRZ), gamma subunit (NCBI) compare
b0627 tatE +0.7 2.5 twin arginine translocase protein E (NCBI) compare
b1341 b1341 +0.7 4.2 orf, hypothetical protein (VIMSS) compare
b1358 ydaT +0.7 1.4 Rac prophage; predicted protein (NCBI) compare
b0661 miaB +0.7 4.5 isopentenyl-adenosine A37 tRNA methylthiolase (NCBI) compare
b1450 b1450 +0.6 3.9 orf, hypothetical protein (VIMSS) compare
b1040 csgD +0.6 1.9 DNA-binding transcriptional activator in two-component regulatory system (NCBI) compare
b1628 rsxB +0.6 1.7 electron transport complex protein RnfB (NCBI) compare
b1037 csgG +0.6 5.2 outer membrane lipoprotein (NCBI) compare
b1557 cspB +0.6 1.4 Qin prophage; cold shock protein (NCBI) compare
b2127 mlrA +0.6 3.5 DNA-binding transcriptional regulator (NCBI) compare
b3206 npr +0.6 3.8 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) compare
b1632 rsxE +0.6 4.3 NADH-ubiquinone oxidoreductase (NCBI) compare
b1725 yniA +0.6 2.9 predicted phosphotransferase/kinase (NCBI) compare
b2262 menB +0.6 2.1 naphthoate synthase (NCBI) compare
b4217 ytfK +0.6 3.8 orf, hypothetical protein (VIMSS) compare
b1784 yeaH +0.6 3.9 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b3644 yicC +0.6 3.2 hypothetical protein (NCBI) compare
b2535 csiE +0.6 5.0 orf, hypothetical protein (VIMSS) compare
b1039 csgE +0.6 4.5 predicted transport protein (NCBI) compare
b1650 nemA +0.6 3.6 N-ethylmaleimide reductase, FMN-linked (NCBI) compare
b4450 arcZ +0.6 2.6 sRNA antisense regulator of tpx and sdaA, Hfq-dependent (RefSeq) compare
b4695 ykgT +0.6 2.2 no description compare
b1191 b1191 +0.6 4.1 orf, hypothetical protein (VIMSS) compare
b1083 flgL +0.6 3.8 flagellar hook-associated protein L (NCBI) compare
b4373 rimI +0.6 2.6 ribosomal-protein-alanine N-acetyltransferase (NCBI) compare
b1818 manY +0.5 2.6 mannose-specific enzyme IIC component of PTS (NCBI) compare
b4515 ybgT +0.5 1.6 hypothetical protein (NCBI) compare
b2829 ptsP +0.5 4.6 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b1731 cedA +0.5 1.7 cell division modulator (RefSeq) compare
b3133 agaV +0.5 1.6 PTS system, cytoplasmic, N-acetylgalactosamine-specific IIB component 2 (EIIB-AGA) (VIMSS) compare
b4171 miaA +0.5 2.1 tRNA delta(2)-isopentenylpyrophosphate transferase (NCBI) compare
b1566 flxA +0.5 2.7 Qin prophage; predicted protein (NCBI) compare
b4110 yjcZ +0.5 3.6 orf, hypothetical protein (VIMSS) compare
b1783 yeaG +0.5 2.8 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b0643 ybeL +0.5 4.1 hypothetical protein (NCBI) compare
b1630 rsxD +0.5 3.5 electron transport complex protein RnfD (NCBI) compare
b1243 oppA +0.5 2.9 oligopeptide transporter subunit (NCBI) compare
b4522 yciX_1 +0.5 1.9 hypothetical protein (NCBI) compare
b1171 b1171 +0.5 2.0 orf, hypothetical protein (VIMSS) compare
b2007 yeeX +0.5 2.2 conserved protein (RefSeq) compare
b2067 yegE +0.5 4.2 predicted diguanylate cyclase, GGDEF domain signalling protein (NCBI) compare
b2742 nlpD +0.5 2.3 predicted outer membrane lipoprotein (NCBI) compare
b1155 ymfS +0.5 2.3 e14 prophage; predicted protein (NCBI) compare
b1778 yeaA +0.5 1.6 methionine sulfoxide reductase B (NCBI) compare
b1669 ydhT +0.5 2.2 hypothetical protein (NCBI) compare
b1188 ycgB +0.5 3.9 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b1271 yciK +0.5 2.2 short chain dehydrogenase (NCBI) compare
b4543 ypaA +0.5 2.1 predicted protein (NCBI) compare
b1261 trpB +0.5 1.5 tryptophan synthase subunit beta (NCBI) compare
b3494 yhiO +0.5 3.1 universal stress protein UspB (NCBI) compare
b0059 hepA +0.5 4.4 ATP-dependent helicase HepA (NCBI) compare
b0850 ybjC +0.5 1.7 predicted inner membrane protein (NCBI) compare
b1217 chaB +0.5 1.2 cation transport regulator (NCBI) compare
b1072 flgA +0.5 1.6 flagellar basal body P-ring biosynthesis protein A (NCBI) compare
b1583 ynfB +0.5 1.1 hypothetical protein (NCBI) compare
b4592 yccB +0.5 1.8 hypothetical protein (RefSeq) compare
b1685 ydiH +0.5 1.0 predicted protein (RefSeq) compare
b2004 yeeU +0.5 2.8 CP4-44 prophage; antitoxin of the YeeV-YeeU toxin-antitoxin system (NCBI) compare
b4094 phnN +0.5 1.7 ribose 1,5-bisphosphokinase (NCBI) compare
b4071 nrfB +0.4 1.5 formate-dependent nitrite reductase; a penta-haeme cytochrome c (VIMSS) compare
b1418 cybB +0.4 1.3 cytochrome b(561) (VIMSS) compare
b3181 greA +0.4 2.6 transcription elongation factor: cleaves 3' nucleotide of paused mRNA (VIMSS) compare
b4413 sokC +0.4 1.1 regulatory antisense RNA (NCBI) compare
b3963 fabR +0.4 3.9 DNA-binding transcriptional repressor (RefSeq) compare
b0605 ahpC +0.4 2.3 alkyl hydroperoxide reductase, C22 subunit (NCBI) compare
b4692 oweE +0.4 2.0 no description compare
b4096 phnL +0.4 1.8 carbon-phosphorus lyase complex subunit (NCBI) compare
b1079 flgH +0.4 2.4 flagellar L-ring protein precursor H (NCBI) compare
b2111 yehD +0.4 1.8 predicted fimbrial-like adhesin protein (NCBI) compare
b1755 ynjC +0.4 2.3 fused transporter subunits of ABC superfamily: membrane components (RefSeq) compare
b1591 b1591 +0.4 1.5 putative oxidoreductase component (VIMSS) compare
b2356 yfdM +0.4 1.6 orf, hypothetical protein (VIMSS) compare
b4493 gapC +0.4 1.7 no description compare
b1247 oppF +0.4 2.2 oligopeptide transporter subunit (NCBI) compare
b4370 leuQ +0.4 1.4 tRNA-Leu (NCBI) compare
b4402 yjjY +0.4 0.8 hypothetical protein (NCBI) compare
b1394 paaG +0.4 1.8 enoyl-CoA hydratase (NCBI) compare
b0920 ycbC +0.4 2.7 conserved inner membrane protein (NCBI) compare
b1942 fliJ +0.4 1.2 flagellar biosynthesis chaperone (NCBI) compare
b3238 yhcN +0.4 1.3 orf, hypothetical protein (VIMSS) compare
b1865 nudB +0.4 1.6 dATP pyrophosphohydrolase (NCBI) compare
b2784 relA +0.4 3.4 (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) compare
b2377 yfdY +0.4 2.2 predicted inner membrane protein (NCBI) compare
b2570 rseC +0.4 2.8 RseC protein involved in reduction of the SoxR iron-sulfur cluster (NCBI) compare
b0746 valZ +0.4 1.7 tRNA-Val (NCBI) compare
b1025 ycdT +0.4 1.2 predicted diguanylate cyclase (NCBI) compare
b1513 lsrA +0.4 2.1 fused AI2 transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b2447 yffP +0.4 2.4 CPZ-55 prophage; predicted protein (NCBI) compare
b1847 yebF +0.4 1.1 predicted protein (RefSeq) compare
b3916 pfkA +0.4 1.6 6-phosphofructokinase (NCBI) compare
b2814 metZ +0.4 1.1 tRNA-Met (NCBI) compare
b4294 insA-7 +0.4 1.5 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b1074 flgC +0.4 1.6 flagellar basal-body rod protein C (NCBI) compare
b4066 yjcF +0.4 0.5 hypothetical protein (NCBI) compare
b1923 fliC +0.4 3.2 flagellin (NCBI) compare
b2317 dedA +0.4 1.5 conserved inner membrane protein (NCBI) compare
b1924 fliD +0.4 2.3 flagellar capping protein (NCBI) compare
b1380 ldhA +0.4 1.4 D-lactate dehydrogenase (NCBI) compare
b1609 rstB +0.4 1.9 sensory histidine kinase in two-component regulatory system with RstA (NCBI) compare
b1080 flgI +0.4 3.0 homolog of Salmonella P-ring of flagella basal body (VIMSS) compare
b2218 rcsC +0.4 3.2 hybrid sensory kinase in two-component regulatory system with RcsB and YojN (RefSeq) compare
b2236 yfaE +0.4 2.3 predicted 2Fe-2S cluster-containing protein (NCBI) compare
b1595 ynfL +0.4 1.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b4630 ykgP +0.4 1.0 no description compare
b1617 uidA +0.4 2.5 beta-D-glucuronidase (NCBI) compare
b1879 flhA +0.4 2.8 flagellar biosynthesis protein A (NCBI) compare
b0953 rmf +0.4 1.9 ribosome modulation factor (NCBI) compare
b1916 sdiA +0.4 2.9 DNA-binding transcriptional activator (NCBI) compare
b4409 blr +0.4 2.8 beta-lactam resistance membrane protein (NCBI) compare
b1462 b1462 +0.4 1.7 orf, hypothetical protein (VIMSS) compare
b1792 yeaO +0.4 2.2 orf, hypothetical protein (VIMSS) compare
b3484 yhhI +0.4 1.4 predicted transposase (NCBI) compare
b0406 tgt +0.4 2.7 queuine tRNA-ribosyltransferase (NCBI) compare
b3250 mreC +0.4 1.3 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b1048 mdoG +0.4 2.5 glucan biosynthesis protein, periplasmic (NCBI) compare
b0423 thiI +0.4 2.8 thiamine biosynthesis protein ThiI (NCBI) compare
b2012 yeeD +0.4 0.9 hypothetical protein (NCBI) compare
b1971 yedY +0.4 2.0 hypothetical protein (NCBI) compare
b1629 rsxC +0.4 2.5 electron transport complex protein RnfC (NCBI) compare
b4503 yafF +0.4 0.5 no description compare
b1667 ydhR +0.4 1.7 hypothetical protein (NCBI) compare
b1954 dsrA +0.4 0.7 regulatory antisense RNA (NCBI) compare
b1244 oppB +0.4 2.2 oligopeptide permease ABC transporter membrane protein (NCBI) compare
b1890 motA +0.4 1.7 flagellar motor protein MotA (NCBI) compare
b3106 yhaK +0.4 1.4 predicted pirin-related protein (NCBI) compare
b4341 yjiS +0.4 2.5 hypothetical protein (NCBI) compare
b2216 rcsD +0.4 3.0 phosphotransfer intermediate protein in two-component regulatory system with RcsBC (NCBI) compare
b0630 lipB +0.4 0.9 protein of lipoate biosynthesis (VIMSS) compare
b2962 yggX +0.4 1.9 hypothetical protein (NCBI) compare
b4603 rseX +0.3 0.4 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b4000 hupA +0.3 1.4 HU, DNA-binding transcriptional regulator, alpha subunit (NCBI) compare
b4461 yfjD +0.3 2.9 predicted inner membrane protein (RefSeq) compare
b0015 dnaJ +0.3 2.7 chaperone Hsp40, co-chaperone with DnaK (NCBI) compare
b2666 yqaE +0.3 2.3 predicted membrane protein (NCBI) compare
b1946 fliN +0.3 2.2 flagellar motor switch protein (NCBI) compare
b3842 rfaH +0.3 2.4 transcriptional activator RfaH (NCBI) compare
b0685 ybfE +0.3 1.7 orf, hypothetical protein (VIMSS) compare
b1943 fliK +0.3 2.0 flagellar hook-length control protein (NCBI) compare
b2618 b2618 +0.3 1.3 orf, hypothetical protein (VIMSS) compare
b0303 ykgI +0.3 0.5 orf, hypothetical protein (VIMSS) compare
b1941 fliI +0.3 2.6 flagellum-specific ATP synthase (NCBI) compare
b1085 b1085 +0.3 1.0 orf, hypothetical protein (VIMSS) compare
b3924 fpr +0.3 2.1 ferredoxin-NADP reductase (NCBI) compare
b0784 moaD +0.3 1.3 molybdopterin synthase, small subunit (NCBI) compare
b1110 ycfJ +0.3 1.8 hypothetical protein (NCBI) compare
b1349 recT +0.3 1.7 Rac prophage; recombination and repair protein (NCBI) compare
b4618 tisB +0.3 2.3 lexA-regulated toxic peptide (RefSeq) compare
b1880 flhB +0.3 2.4 flagellar biosynthesis protein B (NCBI) compare
b1326 mpaA +0.3 1.4 murein peptide amidase A (RefSeq) compare
b3432 glgB +0.3 2.8 glycogen branching enzyme (NCBI) compare
b1412 azoR +0.3 1.6 acyl carrier protein phosphodiesterase (NCBI) compare
b2910 zapA +0.3 1.7 protein that localizes to the cytokinetic ring (NCBI) compare
b4655 ythA +0.3 0.4 expressed protein (RefSeq) compare
b4477 dgoA +0.3 1.9 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (NCBI) compare
b1041 csgB +0.3 1.8 curlin nucleator protein, minor subunit in curli complex (NCBI) compare
b1049 mdoH +0.3 2.4 glucosyltransferase MdoH (NCBI) compare
b4418 sraB +0.3 1.0 unknown RNA (NCBI) compare
b1531 marA +0.3 1.6 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b4152 frdC +0.3 1.6 fumarate reductase subunit C (NCBI) compare
b1255 yciC +0.3 1.3 hypothetical protein (NCBI) compare
b0542 renD +0.3 0.9 orf, hypothetical protein (VIMSS) compare
b0227 yafL +0.3 2.4 predicted lipoprotein and C40 family peptidase (NCBI) compare
b4293 fecI +0.3 1.1 KpLE2 phage-like element; RNA polymerase, sigma 19 factor (NCBI) compare
b2506 yfgI +0.3 0.8 hypothetical protein (NCBI) compare
b2061 wzb +0.3 1.1 protein-tyrosine phosphatase (NCBI) compare
b3224 nanT +0.3 2.1 sialic acid transporter (VIMSS) compare
b4109 yjdA +0.3 2.7 conserved protein with nucleoside triphosphate hydrolase domain (NCBI) compare
b2538 hcaE +0.3 1.7 3-phenylpropionate dioxygenase, large (alpha) subunit (NCBI) compare
b4571 wbbL +0.3 1.0 no description compare
b0870 ltaE +0.3 1.1 L-allo-threonine aldolase, PLP-dependent (NCBI) compare
b2498 upp +0.3 1.3 uracil phosphoribosyltransferase (VIMSS) compare
b1295 ymjA +0.3 1.3 hypothetical protein (NCBI) compare
b3404 envZ +0.3 2.4 osmolarity sensor protein (NCBI) compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source Ying_AminoAcid20 in Escherichia coli BW25113

For carbon source Ying_AminoAcid20 across organisms