Experiment set57IT021 for Escherichia coli BW25113

Compare to:

Ying_all64 rep C; time point 2

200 most detrimental genes:

  gene name fitness t score description  
b4552 yrhC +1.3 2.6 no description compare
b2642 yfjW +1.1 1.5 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b4520 ymgF +0.9 1.6 hypothetical protein (NCBI) compare
b2168 fruK +0.9 2.5 1-phosphofructokinase (NCBI) compare
b1070 flgN +0.8 2.4 export chaperone for FlgK and FlgL (NCBI) compare
b3863 polA +0.8 1.7 DNA polymerase I (NCBI) compare
b4279 yjhB +0.8 0.9 putative transport protein (VIMSS) compare
b1150 ymfR +0.8 1.6 e14 prophage; predicted protein (NCBI) compare
b2236 yfaE +0.7 2.6 predicted 2Fe-2S cluster-containing protein (NCBI) compare
b4451 ryhB +0.7 1.6 Regulatory sRNA mediating positive Fur regulon response; requires Hfq for function; global iron regulator; degraded by RNase E when bound to target (RefSeq) compare
b1358 ydaT +0.7 2.0 Rac prophage; predicted protein (NCBI) compare
b1613 manA +0.6 1.5 mannose-6-phosphate isomerase (VIMSS) compare
b1936 intG +0.6 1.4 predicted defective phage integrase (pseudogene) (RefSeq) compare
b4651 yibW +0.6 0.6 no description compare
b1882 cheY +0.6 0.8 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b3382 yhfY +0.6 2.8 orf, hypothetical protein (VIMSS) compare
b1946 fliN +0.5 2.5 flagellar motor switch protein (NCBI) compare
b0234 yafP +0.5 1.6 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b4493 gapC +0.5 1.5 no description compare
b1279 yciS +0.5 1.0 conserved inner membrane protein (NCBI) compare
b0549 ybcO +0.5 1.5 DLP12 prophage; predicted protein (NCBI) compare
b4655 ythA +0.5 1.2 expressed protein (RefSeq) compare
b0858 ybjO +0.5 2.0 predicted inner membrane protein (NCBI) compare
b2911 ssrS +0.5 1.5 6S regulatory RNA (NCBI) compare
b2114 metG +0.5 1.3 methionyl-tRNA synthetase (NCBI) compare
b2659 b2659 +0.5 1.7 orf, hypothetical protein (VIMSS) compare
b4436 ryeC +0.5 1.6 Novel sRNA, function unknown; paralogous to the other QUAD sRNA genes unknown (RefSeq) compare
b3107 yhaL +0.5 1.3 orf, hypothetical protein (VIMSS) compare
b2259 pmrD +0.5 0.9 polymyxin resistance protein B (VIMSS) compare
b1480 sra +0.5 0.8 30S ribosomal subunit protein S22 (NCBI) compare
b4402 yjjY +0.5 1.0 hypothetical protein (NCBI) compare
b2579 yfiD +0.4 1.5 pyruvate formate lyase subunit (NCBI) compare
b4441 glmY +0.4 1.4 sRNA activator of glmS mRNA (RefSeq) compare
b1609 rstB +0.4 2.5 sensory histidine kinase in two-component regulatory system with RstA (NCBI) compare
b3120 yhaB +0.4 1.3 orf, hypothetical protein (VIMSS) compare
b1926 fliT +0.4 2.0 predicted chaperone (NCBI) compare
b4418 sraB +0.4 0.8 unknown RNA (NCBI) compare
b4172 hfq +0.4 0.6 RNA-binding protein Hfq (NCBI) compare
b1822 rrmA +0.4 1.5 23S rRNA m1G745 methyltransferase (NCBI) compare
b1073 flgB +0.4 2.4 flagellar basal-body rod protein B (NCBI) compare
b3206 npr +0.4 2.2 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) compare
b0564 appY +0.4 0.7 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b0367 tauC +0.4 1.7 taurine transporter subunit (NCBI) compare
b1847 yebF +0.4 0.7 predicted protein (RefSeq) compare
b1550 b1550 +0.4 1.2 orf, hypothetical protein (VIMSS) compare
b4646 yrdE +0.4 2.4 no description compare
b4647 mokA +0.4 0.5 no description compare
b2817 b2817 +0.4 3.0 putative amidase (VIMSS) compare
b1540 ydfH +0.4 1.1 predicted DNA-binding transcriptional regulator (NCBI) compare
b1961 dcm +0.4 1.0 DNA cytosine methylase (NCBI) compare
b1064 grxB +0.4 3.1 glutaredoxin 2 (Grx2) (NCBI) compare
b1344 ydaO +0.4 1.2 predicted C32 tRNA thiolase (NCBI) compare
b4620 yjbT +0.4 2.5 hypothetical protein, no homologs (RefSeq) compare
b1960 vsr +0.4 1.7 DNA mismatch endonuclease of very short patch repair (NCBI) compare
b1442 ydcU +0.4 2.2 predicted spermidine/putrescine transporter subunit (NCBI) compare
b2372 yfdV +0.4 2.3 predicted transporter (NCBI) compare
b0850 ybjC +0.4 1.3 predicted inner membrane protein (NCBI) compare
b4181 yjfI +0.4 1.9 hypothetical protein (NCBI) compare
b1731 cedA +0.4 1.4 cell division modulator (RefSeq) compare
b3766 ilvL +0.4 2.1 ilvG operon leader peptide (NCBI) compare
b0866 ybjQ +0.4 0.9 hypothetical protein (NCBI) compare
b4519 icdC +0.4 1.5 no description compare
b4573 insZ +0.4 1.6 no description compare
b2905 gcvT +0.4 2.6 glycine cleavage system aminomethyltransferase T (NCBI) compare
b1134 ymfB +0.4 1.7 bifunctional thiamin pyrimidine pyrophosphate hydrolase/ thiamin pyrophosphate hydrolase (NCBI) compare
b3512 GadE +0.4 1.7 acid-responsive regulator of gadA and gadBC (Katherine Huang) compare
b4408 csrB +0.4 1.9 CsrA-binding sRNA, antagonizing CsrA regulation (NCBI) compare
b2447 yffP +0.4 2.2 CPZ-55 prophage; predicted protein (NCBI) compare
b1547 stfQ +0.4 2.1 Qin prophage; predicted side tail fibre assembly protein (NCBI) compare
b4060 yjcB +0.4 2.4 orf, hypothetical protein (VIMSS) compare
b1278 pgpB +0.4 1.8 phosphatidylglycerophosphatase B (NCBI) compare
b4692 oweE +0.4 1.7 no description compare
b0851 nfsA +0.4 1.5 nitroreductase A, NADPH-dependent, FMN-dependent (NCBI) compare
b0580 ybdJ +0.3 1.1 predicted inner membrane protein (NCBI) compare
b3979 thrT +0.3 0.3 tRNA-Thr (NCBI) compare
b0991 ymcE +0.3 1.8 cold shock gene (NCBI) compare
b1302 puuE +0.3 1.9 GABA aminotransferase, PLP-dependent (NCBI) compare
b1850 eda +0.3 0.7 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase (NCBI) compare
b0388 aroL +0.3 2.3 shikimate kinase II (NCBI) compare
b1119 nagK +0.3 1.8 N-acetyl-D-glucosamine kinase (NCBI) compare
b2829 ptsP +0.3 3.0 fused PTS enzyme: PEP-protein phosphotransferase (enzyme I)/GAF domain containing protein (NCBI) compare
b0521 ybcF +0.3 1.6 predicted carbamate kinase (NCBI) compare
b1108 ycfP +0.3 1.8 orf, hypothetical protein (VIMSS) compare
b1725 yniA +0.3 2.2 predicted phosphotransferase/kinase (NCBI) compare
b0881 clpS +0.3 0.9 ATP-dependent Clp protease adaptor protein ClpS (NCBI) compare
b2910 zapA +0.3 1.7 protein that localizes to the cytokinetic ring (NCBI) compare
b1217 chaB +0.3 0.7 cation transport regulator (NCBI) compare
b1753 ynjA +0.3 1.4 hypothetical protein (NCBI) compare
b2485 hyfE +0.3 2.2 hydrogenase 4, membrane subunit (NCBI) compare
b1063 yceB +0.3 1.6 predicted lipoprotein (NCBI) compare
b1527 yneK +0.3 1.3 hypothetical protein (NCBI) compare
b1493 gadB +0.3 0.5 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b4196 ulaD +0.3 1.6 3-keto-L-gulonate 6-phosphate decarboxylase (NCBI) compare
b3130 yhaV +0.3 1.9 hypothetical protein (NCBI) compare
b2706 gutM +0.3 1.5 DNA-binding transcriptional activator of glucitol operon (NCBI) compare
b1598 ydgD +0.3 1.9 predicted peptidase (NCBI) compare
b1841 yobA +0.3 1.0 hypothetical protein (NCBI) compare
b2096 gatY +0.3 2.1 tagatose-bisphosphate aldolase 1 (VIMSS) compare
b2272 yfbM +0.3 1.5 hypothetical protein (NCBI) compare
b2544 yphB +0.3 2.1 hypothetical protein (NCBI) compare
b1963 b1963 +0.3 2.0 orf, hypothetical protein (VIMSS) compare
b1890 motA +0.3 2.0 flagellar motor protein MotA (NCBI) compare
b3138 agaB +0.3 1.2 N-acetylgalactosamine-specific enzyme IIB component of PTS (NCBI) compare
b1035 ycdY +0.3 2.1 hypothetical protein (NCBI) compare
b0979 appB +0.3 1.3 cytochrome bd-II oxidase, subunit II (NCBI) compare
b0784 moaD +0.3 1.3 molybdopterin synthase, small subunit (NCBI) compare
b1723 pfkB +0.3 1.9 6-phosphofructokinase II; suppressor of pfkA (VIMSS) compare
b3083 ygjN +0.3 1.9 hypothetical protein (NCBI) compare
b4045 yjbJ +0.3 0.9 predicted stress response protein (NCBI) compare
b4630 ykgP +0.3 1.3 no description compare
b0210 yafE +0.3 1.7 predicted S-adenosyl-L-methionine-dependent methyltransferase (NCBI) compare
b2847 yqeI +0.3 0.5 predicted transcriptional regulator (NCBI) compare
b4435 isrC +0.3 0.7 unknown RNA (NCBI) compare
b2506 yfgI +0.3 0.9 hypothetical protein (NCBI) compare
b2258 b2258 +0.3 0.6 putative transport/receptor protein (VIMSS) compare
b1930 yedF +0.3 1.3 hypothetical protein (NCBI) compare
b4699 fnrS +0.3 0.5 FNR-activated anaerobic sRNA antisense regulator down regulates cydDC, metE, sodA, sodB, Hfq-dependent; mediates negative FNR regulation (RefSeq) compare
b2369 evgA +0.3 1.3 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b2645 yfjZ +0.3 1.6 CP4-57 prophage; antitoxin of the YpjF-YfjZ toxin-antitoxin system (NCBI) compare
b3262 yhdJ +0.3 2.0 putative methyltransferase (VIMSS) compare
b1343 dbpA +0.3 1.6 ATP-dependent RNA helicase, specific for 23S rRNA (NCBI) compare
b2792 yqcC +0.3 1.2 hypothetical protein (NCBI) compare
b0142 folK +0.3 0.4 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b4577 sgrS +0.3 1.1 small antisense RNA (NCBI) compare
b4648 ysaC +0.3 1.4 no description compare
b1106 ycfN +0.3 1.5 thiamin kinase (NCBI) compare
b1600 mdtJ +0.3 0.8 multidrug efflux system transporter (NCBI) compare
b4177 purA +0.3 0.7 adenylosuccinate synthetase (NCBI) compare
b3086 ygjQ +0.3 1.7 predicted thioredoxin-like (NCBI) compare
b2500 purN +0.3 1.7 phosphoribosylglycinamide formyltransferase (NCBI) compare
b2510 b2510 +0.3 1.0 orf, hypothetical protein (VIMSS) compare
b1415 aldA +0.3 1.6 Lactaldehyde / glycolaldehyde dehydrogenase aldA (EC 1.2.1.22; EC 1.2.1.21) (from data) compare
b1155 ymfS +0.3 1.6 e14 prophage; predicted protein (NCBI) compare
b1085 b1085 +0.3 1.1 orf, hypothetical protein (VIMSS) compare
b1075 flgD +0.3 1.0 flagellar basal body rod modification protein D (NCBI) compare
b2080 b2080 +0.3 0.9 orf, hypothetical protein (VIMSS) compare
b1079 flgH +0.3 1.7 flagellar L-ring protein precursor H (NCBI) compare
b0458 ylaC +0.3 1.8 orf, hypothetical protein (VIMSS) compare
b4513 kdpF +0.3 1.1 potassium ion accessory transporter subunit (NCBI) compare
b4110 yjcZ +0.3 2.0 orf, hypothetical protein (VIMSS) compare
b1829 htpX +0.3 1.3 heat shock protein HtpX (NCBI) compare
b4686 yshB +0.3 1.8 expressed protein (RefSeq) compare
b2505 yfgH +0.3 1.7 predicted outer membrane lipoprotein (NCBI) compare
b4227 ytfQ +0.3 1.3 predicted sugar transporter subunit: periplasmic-binding component of ABC superfamily (NCBI) compare
b0387 yaiI +0.3 1.7 orf, hypothetical protein (VIMSS) compare
b1887 cheW +0.3 1.5 purine-binding chemotaxis protein (NCBI) compare
b1231 tyrT +0.3 0.5 tRNA-Tyr (NCBI) compare
b1450 b1450 +0.3 1.2 orf, hypothetical protein (VIMSS) compare
b1992 cobS +0.3 0.8 cobalamin synthase (NCBI) compare
b4461 yfjD +0.3 1.9 predicted inner membrane protein (RefSeq) compare
b1586 b1586 +0.3 1.2 orf, hypothetical protein (VIMSS) compare
b3905 rhaS +0.3 2.0 DNA-binding transcriptional activator, L-rhamnose-binding (NCBI) compare
b3658 selC +0.3 1.3 tRNA-Sec (NCBI) compare
b1868 yecE +0.3 1.1 hypothetical protein (NCBI) compare
b4614 sokA +0.3 1.0 no description compare
b2019 hisG +0.3 1.8 ATP phosphoribosyltransferase (NCBI) compare
b1952 dsrB +0.3 1.5 hypothetical protein (NCBI) compare
b3280 yrdB +0.3 1.1 hypothetical protein (NCBI) compare
b3950 frwB +0.3 1.1 predicted enzyme IIB component of PTS (NCBI) compare
b1433 b1433 +0.3 1.1 putative membrane transport protein (VIMSS) compare
b1661 cfa +0.3 1.3 cyclopropane fatty acyl phospholipid synthase (unsaturated-phospholipid methyltransferase) (NCBI) compare
b1755 ynjC +0.3 1.2 fused transporter subunits of ABC superfamily: membrane components (RefSeq) compare
b1633 nth +0.3 1.6 DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) (NCBI) compare
b1377 ompN +0.3 1.4 outer membrane pore protein N, non-specific (NCBI) compare
b2012 yeeD +0.3 1.4 hypothetical protein (NCBI) compare
b3028 mdaB +0.3 1.6 NADPH quinone reductase (NCBI) compare
b4535 yniD +0.2 0.5 predicted protein (RefSeq) compare
b1271 yciK +0.2 1.4 short chain dehydrogenase (NCBI) compare
b3644 yicC +0.2 1.7 hypothetical protein (NCBI) compare
b0191 yaeJ +0.2 1.6 hypothetical protein (NCBI) compare
b0379 yaiY +0.2 1.6 predicted inner membrane protein (NCBI) compare
b4613 dinQ +0.2 0.8 Damage inducible, function unknown (RefSeq) compare
b0643 ybeL +0.2 1.5 hypothetical protein (NCBI) compare
b0965 b0965 +0.2 0.9 orf, hypothetical protein (VIMSS) compare
b2450 yffS +0.2 0.8 CPZ-55 prophage; predicted protein (RefSeq) compare
b2181 yejG +0.2 1.2 hypothetical protein (NCBI) compare
b2625 yfjI +0.2 0.6 CP4-57 prophage; predicted protein (NCBI) compare
b0621 dcuC +0.2 1.9 anaerobic C4-dicarboxylate transport (NCBI) compare
b1685 ydiH +0.2 0.6 predicted protein (RefSeq) compare
b2448 yffQ +0.2 1.4 CPZ-55 prophage; predicted protein (RefSeq) compare
b2134 pbpG +0.2 1.9 penicillin-binding protein 7 (VIMSS) compare
b4012 yjaB +0.2 1.4 predicted acetyltransferase (NCBI) compare
b2120 yehM +0.2 1.7 hypothetical protein (NCBI) compare
b0393 rdgC +0.2 2.0 recombination associated protein (NCBI) compare
b1474 fdnG +0.2 1.6 formate dehydrogenase-N, alpha subunit, nitrate-inducible (NCBI) compare
b4509 ylcG +0.2 1.1 DLP12 prophage; predicted protein (NCBI) compare
b4642 yoeD +0.2 0.7 no description compare
b4269 yjgB +0.2 1.5 putative oxidoreductase (VIMSS) compare
b4644 ypjI +0.2 1.1 no description compare
b1567 intK +0.2 0.9 Qin prophage; predicted protein (RefSeq) compare
b2537 hcaR +0.2 1.5 DNA-binding transcriptional activator of 3-phenylpropionic acid catabolism (NCBI) compare
b3059 ygiH +0.2 1.5 hypothetical protein (NCBI) compare
b2794 yqcD +0.2 1.8 hypothetical protein (NCBI) compare
b1940 fliH +0.2 1.4 flagellar biosynthesis; export of flagellar proteins? (VIMSS) compare
b1874 cutC +0.2 0.9 copper homeostasis protein (NCBI) compare
b0218 yafU +0.2 0.9 predicted inner membrane protein (RefSeq) compare
b1679 sufE +0.2 0.8 cysteine desufuration protein SufE (NCBI) compare
b3641 ttk +0.2 1.8 putative transcriptional regulator (VIMSS) compare
b1382 ynbE +0.2 0.6 predicted lipoprotein (NCBI) compare
b0440 hupB +0.2 1.2 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare


Specific Phenotypes

For 1 genes in this experiment

For carbon source Ying_all64 in Escherichia coli BW25113

For carbon source Ying_all64 across organisms