Experiment set57IT020 for Escherichia coli BW25113

Compare to:

Ying_all64 rep B; time point 2

200 most detrimental genes:

  gene name fitness t score description  
b0564 appY +1.4 2.2 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b4402 yjjY +1.1 1.8 hypothetical protein (NCBI) compare
b4655 ythA +1.0 1.4 expressed protein (RefSeq) compare
b1823 cspC +0.9 2.2 stress protein, member of the CspA-family (NCBI) compare
b4520 ymgF +0.9 1.8 hypothetical protein (NCBI) compare
b1217 chaB +0.8 2.2 cation transport regulator (NCBI) compare
b2934 cmtB +0.8 1.5 predicted mannitol-specific enzyme IIA component of PTS (NCBI) compare
b2259 pmrD +0.8 1.5 polymyxin resistance protein B (VIMSS) compare
b2642 yfjW +0.7 1.2 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b1730 ydjO +0.7 1.2 predicted protein (RefSeq) compare
b4418 sraB +0.7 1.6 unknown RNA (NCBI) compare
b2110 yehC +0.7 1.8 predicted periplasmic pilin chaperone (NCBI) compare
b2012 yeeD +0.7 3.7 hypothetical protein (NCBI) compare
b4048 yjbM +0.7 1.8 hypothetical protein (NCBI) compare
b1765 ydjA +0.6 1.0 predicted oxidoreductase (NCBI) compare
b3119 tdcR +0.6 2.4 threonine dehydratase operon activator protein (VIMSS) compare
b1842 holE +0.6 2.2 DNA polymerase III, theta subunit (NCBI) compare
b1949 fliQ +0.6 3.0 flagellar biosynthesis protein Q (NCBI) compare
b4172 hfq +0.6 0.9 RNA-binding protein Hfq (NCBI) compare
b2369 evgA +0.6 2.9 DNA-binding response regulator in two-component regulatory system with EvgS (NCBI) compare
b1279 yciS +0.6 1.1 conserved inner membrane protein (NCBI) compare
b1600 mdtJ +0.6 1.9 multidrug efflux system transporter (NCBI) compare
b1257 yciE +0.6 0.6 hypothetical protein (NCBI) compare
b1950 fliR +0.6 2.7 flagellar biosynthesis protein R (NCBI) compare
b2911 ssrS +0.6 1.5 6S regulatory RNA (NCBI) compare
b1595 ynfL +0.6 1.8 predicted DNA-binding transcriptional regulator (NCBI) compare
b1150 ymfR +0.6 1.0 e14 prophage; predicted protein (NCBI) compare
b1733 chbG +0.6 2.4 hypothetical protein (NCBI) compare
b0014 dnaK +0.6 1.4 molecular chaperone DnaK (NCBI) compare
b4603 rseX +0.5 0.7 sRNA regulating ompA and ompC translation, with Hfq (RefSeq) compare
b1480 sra +0.5 0.7 30S ribosomal subunit protein S22 (NCBI) compare
b1946 fliN +0.5 3.2 flagellar motor switch protein (NCBI) compare
b2114 metG +0.5 1.9 methionyl-tRNA synthetase (NCBI) compare
b4593 ymgI +0.5 0.8 hypothetical protein (RefSeq) compare
b4373 rimI +0.5 1.4 ribosomal-protein-alanine N-acetyltransferase (NCBI) compare
b4497 yeeL +0.5 1.2 no description compare
b2614 grpE +0.5 1.9 heat shock protein (NCBI) compare
b1792 yeaO +0.5 1.8 orf, hypothetical protein (VIMSS) compare
b1865 nudB +0.5 1.5 dATP pyrophosphohydrolase (NCBI) compare
b4345 mcrC +0.5 1.0 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC (NCBI) compare
b2433 b2433 +0.5 1.6 orf, hypothetical protein (VIMSS) compare
b1824 yobF +0.5 2.4 hypothetical protein (NCBI) compare
b3206 npr +0.5 3.3 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) (NCBI) compare
b3766 ilvL +0.5 2.0 ilvG operon leader peptide (NCBI) compare
b1070 flgN +0.5 1.1 export chaperone for FlgK and FlgL (NCBI) compare
b1429 tehA +0.5 0.6 potassium-tellurite ethidium and proflavin transporter (NCBI) compare
b4592 yccB +0.5 1.6 hypothetical protein (RefSeq) compare
b1557 cspB +0.5 1.1 Qin prophage; cold shock protein (NCBI) compare
b4653 yicT +0.5 0.8 no description compare
b4443 gcvB +0.5 0.3 GcvB sRNA gene divergent from gcvA (RefSeq) compare
b0999 cbpM +0.5 2.3 modulator of CbpA co-chaperone (NCBI) compare
b1330 ynaI +0.5 2.3 conserved inner membrane protein (NCBI) compare
b1344 ydaO +0.4 1.9 predicted C32 tRNA thiolase (NCBI) compare
b2579 yfiD +0.4 1.6 pyruvate formate lyase subunit (NCBI) compare
b0866 ybjQ +0.4 0.9 hypothetical protein (NCBI) compare
b0627 tatE +0.4 1.0 twin arginine translocase protein E (NCBI) compare
b1179 ycgL +0.4 1.7 conserved protein (NCBI) compare
b0579 ybdF +0.4 2.2 hypothetical protein (NCBI) compare
b2741 rpoS +0.4 2.6 RNA polymerase sigma factor (NCBI) compare
b0730 mngR +0.4 1.1 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b2005 yeeV +0.4 1.9 CP4-44 prophage; toxin of the YeeV-YeeU toxin-antitoxin system (NCBI) compare
b0937 ssuE +0.4 1.8 NAD(P)H-dependent FMN reductase (NCBI) compare
b2262 menB +0.4 2.2 naphthoate synthase (NCBI) compare
b2419 yfeK +0.4 1.6 hypothetical protein (NCBI) compare
b1038 csgF +0.4 1.6 predicted transport protein (NCBI) compare
b1920 fliY +0.4 1.2 cystine transporter subunit (NCBI) compare
b1900 araG +0.4 2.1 fused L-arabinose transporter subunits of ABC superfamily: ATP-binding components (NCBI) compare
b4543 ypaA +0.4 1.7 predicted protein (NCBI) compare
b1671 ydhX +0.4 1.6 predicted 4Fe-4S ferridoxin-type protein (RefSeq) compare
b0503 ybbB +0.4 1.7 tRNA 2-selenouridine synthase, selenophosphate-dependent (NCBI) compare
b2920 ygfH +0.4 2.9 propionyl-CoA:succinate-CoA transferase (NCBI) compare
b1814 sdaA +0.4 0.8 L-serine deaminase I (NCBI) compare
b1556 b1556 +0.4 1.4 orf, hypothetical protein (VIMSS) compare
b1604 ydgH +0.4 1.6 hypothetical protein (NCBI) compare
b1926 fliT +0.4 1.7 predicted chaperone (NCBI) compare
b1540 ydfH +0.4 1.2 predicted DNA-binding transcriptional regulator (NCBI) compare
b0946 ycbW +0.4 1.9 orf, hypothetical protein (VIMSS) compare
b1493 gadB +0.4 0.5 glutamate decarboxylase B, PLP-dependent (NCBI) compare
b2666 yqaE +0.4 1.5 predicted membrane protein (NCBI) compare
b0641 rlpB +0.4 1.6 minor lipoprotein (NCBI) compare
b1879 flhA +0.4 2.2 flagellar biosynthesis protein A (NCBI) compare
b2706 gutM +0.4 1.3 DNA-binding transcriptional activator of glucitol operon (NCBI) compare
b4491 ycgH +0.4 2.3 no description compare
b1711 btuC +0.4 1.8 vtamin B12-transporter permease (NCBI) compare
b1516 lsrB +0.4 2.3 AI2 transporter (NCBI) compare
b1783 yeaG +0.4 2.4 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b4461 yfjD +0.4 2.7 predicted inner membrane protein (RefSeq) compare
b4585 sroB +0.4 0.8 Novel sRNA, function unknown (RefSeq) compare
b4416 rybA +0.4 0.9 unknown RNA (NCBI) compare
b1004 wrbA +0.4 2.2 TrpR binding protein WrbA (NCBI) compare
b2439 eutL +0.4 2.3 predicted carboxysome structural protein with predicted role in ethanolamine utilization (NCBI) compare
b1164 ycgZ +0.4 0.9 hypothetical protein (NCBI) compare
b3031 yqiA +0.3 2.1 predicted esterase (NCBI) compare
b2209 eco +0.3 1.4 ecotin precursor (NCBI) compare
b1514 lsrC +0.3 0.5 AI2 transporter (NCBI) compare
b1531 marA +0.3 1.8 multiple antibiotic resistance; transcriptional activator of defense systems (VIMSS) compare
b1108 ycfP +0.3 1.2 orf, hypothetical protein (VIMSS) compare
b0858 ybjO +0.3 1.1 predicted inner membrane protein (NCBI) compare
b3890 yiiF +0.3 1.2 orf, hypothetical protein (VIMSS) compare
b0018 mokC +0.3 0.7 regulatory protein for HokC, overlaps CDS of hokC (NCBI) compare
b4559 yjdO +0.3 1.6 hypothetical protein (NCBI) compare
b4522 yciX_1 +0.3 1.1 hypothetical protein (NCBI) compare
b4050 yjbO +0.3 1.4 orf, hypothetical protein (VIMSS) compare
b2672 ygaM +0.3 2.3 orf, hypothetical protein (VIMSS) compare
b1806 yeaY +0.3 1.4 predicted lipoprotein (NCBI) compare
b2726 hypA +0.3 1.7 protein involved in nickel insertion into hydrogenases 3 (NCBI) compare
b1977 asnT +0.3 1.5 tRNA-Asn (NCBI) compare
b2539 hcaF +0.3 1.8 3-phenylpropionate dioxygenase, small (beta) subunit (NCBI) compare
b4546 ypeB +0.3 0.7 hypothetical protein (NCBI) compare
b3672 ivbL +0.3 1.8 ilvB operon leader peptide (NCBI) compare
b2377 yfdY +0.3 1.2 predicted inner membrane protein (NCBI) compare
b1171 b1171 +0.3 0.7 orf, hypothetical protein (VIMSS) compare
b1079 flgH +0.3 1.6 flagellar L-ring protein precursor H (NCBI) compare
b3875 ompL +0.3 1.4 predicted outer membrane porin L (NCBI) compare
b0393 rdgC +0.3 2.6 recombination associated protein (NCBI) compare
b0310 ykgH +0.3 0.8 predicted inner membrane protein (NCBI) compare
b1723 pfkB +0.3 1.9 6-phosphofructokinase II; suppressor of pfkA (VIMSS) compare
b3686 ibpB +0.3 2.3 heat shock chaperone (NCBI) compare
b1415 aldA +0.3 2.1 Lactaldehyde / glycolaldehyde dehydrogenase aldA (EC 1.2.1.22; EC 1.2.1.21) (from data) compare
b1883 cheB +0.3 1.6 chemotaxis-specific methylesterase (NCBI) compare
b1433 b1433 +0.3 2.1 putative membrane transport protein (VIMSS) compare
b3688 yidQ +0.3 1.8 orf, hypothetical protein (VIMSS) compare
b1590 ynfH +0.3 1.5 oxidoreductase, membrane subunit (NCBI) compare
b3024 ygiW +0.3 1.2 hypothetical protein (NCBI) compare
b1971 yedY +0.3 1.2 hypothetical protein (NCBI) compare
b1584 speG +0.3 2.3 spermidine N1-acetyltransferase (NCBI) compare
b3512 GadE +0.3 1.3 acid-responsive regulator of gadA and gadBC (Katherine Huang) compare
b4509 ylcG +0.3 0.7 DLP12 prophage; predicted protein (NCBI) compare
b4017 arpA +0.3 1.5 regulator of acetyl CoA synthetase (NCBI) compare
b4646 yrdE +0.3 1.6 no description compare
b2179 yejE +0.3 1.7 predicted oligopeptide transporter subunit (NCBI) compare
b1784 yeaH +0.3 2.0 yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b1567 intK +0.3 0.7 Qin prophage; predicted protein (RefSeq) compare
b3023 ygiV +0.3 1.9 predicted transcriptional regulator (NCBI) compare
b2998 yghW +0.3 1.7 hypothetical protein (NCBI) compare
b0714 nei +0.3 1.4 endonuclease VIII/ 5-formyluracil/5-hydroxymethyluracil DNA glycosylase (NCBI) compare
b1755 ynjC +0.3 1.9 fused transporter subunits of ABC superfamily: membrane components (RefSeq) compare
b0354 yaiL +0.3 1.8 nucleoprotein/polynucleotide-associated enzyme (VIMSS) compare
b0163 yaeH +0.3 1.5 hypothetical protein (NCBI) compare
b3348 slyX +0.3 1.5 hypothetical protein (NCBI) compare
b2445 yffN +0.3 1.5 CPZ-55 prophage; predicted protein (RefSeq) compare
b1992 cobS +0.3 1.1 cobalamin synthase (NCBI) compare
b1252 tonB +0.3 0.9 membrane spanning protein in TonB-ExbB-ExbD complex (NCBI) compare
b4511 ybdZ +0.3 1.3 hypothetical protein (NCBI) compare
b4294 insA-7 +0.3 1.1 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b1639 ydhA +0.3 1.0 orf, hypothetical protein (VIMSS) compare
b2659 b2659 +0.3 0.7 orf, hypothetical protein (VIMSS) compare
b3503 arsC +0.3 2.0 arsenate reductase (NCBI) compare
b1501 YdeP +0.3 2.0 putative oxidoreductase, major subunit, acid resistance protein (Katherine Huang) compare
b3626 rfaJ +0.3 1.4 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase (NCBI) compare
b3238 yhcN +0.3 0.9 orf, hypothetical protein (VIMSS) compare
b0750 nadA +0.3 1.7 quinolinate synthetase (NCBI) compare
b1450 b1450 +0.3 1.4 orf, hypothetical protein (VIMSS) compare
b0001 thrL +0.3 1.2 thr operon leader peptide (NCBI) compare
b2186 yejK +0.3 2.1 nucleoid-associated protein NdpA (NCBI) compare
b2019 hisG +0.3 1.7 ATP phosphoribosyltransferase (NCBI) compare
b1647 ydhF +0.3 1.2 predicted oxidoreductase (NCBI) compare
b0863 artI +0.3 1.4 arginine transporter subunit (NCBI) compare
b0342 lacA +0.3 2.2 galactoside O-acetyltransferase (NCBI) compare
b4409 blr +0.3 1.7 beta-lactam resistance membrane protein (NCBI) compare
b1243 oppA +0.3 1.7 oligopeptide transporter subunit (NCBI) compare
b1751 ydjY +0.3 1.2 orf, hypothetical protein (VIMSS) compare
b1976 b1976 +0.3 1.0 orf, hypothetical protein (VIMSS) compare
b1270 btuR +0.3 1.2 cob(I)yrinic acid a,c-diamide adenosyltransferase (NCBI) compare
b0872 hcr +0.3 1.4 HCP oxidoreductase, NADH-dependent (NCBI) compare
b3998 nfi +0.3 1.4 endonuclease V (deoxyinosine 3'endoduclease) (VIMSS) compare
b2095 gatZ +0.3 1.5 D-tagatose 1,6-bisphosphate aldolase 2, subunit (NCBI) compare
b4644 ypjI +0.3 1.2 no description compare
b0145 dksA +0.3 0.7 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b1605 ydgI +0.3 1.8 predicted arginine/ornithine antiporter transporter (NCBI) compare
b3857 mobA +0.3 1.6 molybdopterin-guanine dinucleotide biosynthesis protein A (NCBI) compare
b1694 ydiF +0.3 1.8 fused predicted acetyl-CoA:acetoacetyl-CoA transferase: alpha subunit/beta subunit (NCBI) compare
b2817 b2817 +0.3 1.5 putative amidase (VIMSS) compare
b1582 ynfA +0.3 1.0 hypothetical protein (NCBI) compare
b0788 ybhN +0.3 1.3 conserved inner membrane protein (NCBI) compare
b0384 psiF +0.3 1.2 induced by phosphate starvation (VIMSS) compare
b1399 paaX +0.3 0.9 DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive (NCBI) compare
b0454 ybaZ +0.3 1.2 predicted methyltransferase (NCBI) compare
b1780 yeaD +0.3 1.7 orf, hypothetical protein (VIMSS) compare
b1890 motA +0.3 1.4 flagellar motor protein MotA (NCBI) compare
b1333 uspE +0.3 1.4 stress-induced protein (NCBI) compare
b0279 yagM +0.3 0.4 CP4-6 prophage; predicted protein (NCBI) compare
b1816 yoaE +0.3 1.6 fused predicted membrane protein/conserved protein (NCBI) compare
b1642 slyA +0.3 0.6 transcriptional regulator for cryptic hemolysin (VIMSS) compare
b2448 yffQ +0.3 1.1 CPZ-55 prophage; predicted protein (RefSeq) compare
b1837 yebW +0.3 0.6 orf, hypothetical protein (VIMSS) compare
b0187 yaeR +0.3 1.7 orf, hypothetical protein (VIMSS) compare
b0493 ybbO +0.3 1.8 short chain dehydrogenase (NCBI) compare
b4151 frdD +0.2 0.7 fumarate reductase subunit D (NCBI) compare
b1710 btuE +0.2 1.6 predicted glutathione peroxidase (NCBI) compare
b2876 b2876 +0.2 1.1 orf, hypothetical protein (VIMSS) compare
b3152 yraR +0.2 1.2 orf, hypothetical protein (VIMSS) compare
b2336 yfcS +0.2 1.7 predicted periplasmic pilus chaperone (NCBI) compare
b2258 b2258 +0.2 0.5 putative transport/receptor protein (VIMSS) compare
b2455 eutE +0.2 1.3 predicted aldehyde dehydrogenase, ethanolamine utilization protein (NCBI) compare
b2971 yghG +0.2 1.6 hypothetical protein (NCBI) compare
b0207 dkgB +0.2 1.6 2,5-diketo-D-gluconate reductase B (NCBI) compare
b3271 yhdZ +0.2 1.5 predicted amino-acid transporter subunit (NCBI) compare
b1519 tam +0.2 1.6 trans-aconitate 2-methyltransferase (NCBI) compare
b1080 flgI +0.2 1.8 homolog of Salmonella P-ring of flagella basal body (VIMSS) compare


Specific Phenotypes

For 1 genes in this experiment

For carbon source Ying_all64 in Escherichia coli BW25113

For carbon source Ying_all64 across organisms