Experiment set57IT017 for Escherichia coli BW25113

Compare to:

Ying_Others16 rep B; time point 1

200 most important genes:

  gene name fitness t score description  
b1231 tyrT -5.2 -1.5 tRNA-Tyr (NCBI) compare
b1506 yneL -4.6 -3.2 predicted transcriptional regulator (NCBI) compare
b1882 cheY -4.2 -1.2 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b1480 sra -3.8 -2.2 30S ribosomal subunit protein S22 (NCBI) compare
b2620 smpB -3.6 -2.4 SsrA-binding protein (NCBI) compare
b1709 btuD -3.5 -1.3 vitamin B12-transporter ATPase (NCBI) compare
b3500 gor -3.5 -3.7 glutathione reductase (NCBI) compare
b2567 rnc -3.4 -2.1 ribonuclease III (NCBI) compare
b3619 rfaD -3.2 -6.3 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b1258 yciF -2.8 -1.9 hypothetical protein (NCBI) compare
b0222 lpcA -2.8 -3.5 phosphoheptose isomerase (NCBI) compare
b0564 appY -2.7 -1.0 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b3863 polA -2.6 -2.2 DNA polymerase I (NCBI) compare
b3870 glnA -2.6 -5.6 glutamine synthetase (NCBI) compare
b2330 yfcB -2.5 -3.0 putative adenine-specific methylase (VIMSS) compare
b4585 sroB -2.5 -1.7 Novel sRNA, function unknown (RefSeq) compare
b0200 gmhB -2.4 -2.6 hypothetical protein (NCBI) compare
b3621 rfaC -2.4 -7.2 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1730 ydjO -2.3 -1.2 predicted protein (RefSeq) compare
b0990 cspG -2.3 -1.5 DNA-binding transcriptional regulator (NCBI) compare
b1293 sapB -2.2 -2.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4520 ymgF -2.2 -2.7 hypothetical protein (NCBI) compare
b0738 tolR -2.1 -4.7 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b4202 rpsR -1.9 -1.8 30S ribosomal protein S18 (NCBI) compare
b2939 yqgB -1.9 -2.0 predicted protein (RefSeq) compare
b2188 yejM -1.9 -8.1 predicted hydrolase, inner membrane (NCBI) compare
b1551 b1551 -1.9 -1.0 orf, hypothetical protein (VIMSS) compare
b1361 ydaW -1.8 -0.7 orf, hypothetical protein (VIMSS) compare
b2259 pmrD -1.8 -1.2 polymyxin resistance protein B (VIMSS) compare
b4416 rybA -1.8 -1.7 unknown RNA (NCBI) compare
b1984 asnW -1.7 -1.4 tRNA-Asn (NCBI) compare
b1058 yceO -1.7 -0.7 hypothetical protein (NCBI) compare
b3021 ygiT -1.7 -2.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b4146 yjeK -1.7 -3.6 predicted lysine aminomutase (NCBI) compare
b3290 trkA -1.7 -3.9 potassium transporter peripheral membrane component (NCBI) compare
b1025 ycdT -1.7 -2.2 predicted diguanylate cyclase (NCBI) compare
b1192 ldcA -1.6 -3.4 L,D-carboxypeptidase A (NCBI) compare
b3631 rfaG -1.6 -10.3 glucosyltransferase I (NCBI) compare
b0438 clpX -1.6 -5.1 ATP-dependent protease ATP-binding subunit (NCBI) compare
b2859 ygeO -1.6 -3.3 hypothetical protein (RefSeq) compare
b1545 pinQ -1.5 -0.4 Qin prophage; predicted site-specific recombinase (NCBI) compare
b0053 surA -1.5 -4.4 peptidyl-prolyl cis-trans isomerase (PPIase) (NCBI) compare
b2853 ygeI -1.5 -0.7 hypothetical protein (NCBI) compare
b0957 ompA -1.5 -3.5 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b2285 nuoE -1.4 -2.5 NADH dehydrogenase subunit E (NCBI) compare
b2912 ygfA -1.4 -3.3 putative ligase (VIMSS) compare
b1182 hlyE -1.4 -0.9 hemolysin E (VIMSS) compare
b4552 yrhC -1.4 -0.6 no description compare
b3052 rfaE -1.4 -3.4 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b1259 yciG -1.4 -2.2 orf, hypothetical protein (VIMSS) compare
b0866 ybjQ -1.3 -1.2 hypothetical protein (NCBI) compare
b0550 rusA -1.3 -2.8 DLP12 prophage; endonuclease RUS (NCBI) compare
b2820 recB -1.3 -2.1 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b3839 tatC -1.3 -4.6 TatABCE protein translocation system subunit (NCBI) compare
b1434 ydcN -1.3 -2.0 predicted DNA-binding transcriptional regulator (NCBI) compare
b1351 racC -1.3 -0.8 Rac prophage; predicted protein (NCBI) compare
b1165 ymgA -1.3 -0.8 hypothetical protein (NCBI) compare
b4239 treC -1.2 -3.5 trehalose-6-P hydrolase (NCBI) compare
b1130 phoP -1.2 -2.2 DNA-binding response regulator in two-component regulatory system with PhoQ (NCBI) compare
b3725 pstB -1.2 -0.8 phosphate transporter subunit (NCBI) compare
b3405 ompR -1.2 -2.7 osmolarity response regulator (NCBI) compare
b3623 rfaK -1.2 -2.4 lipopolysaccharide core biosynthesis (NCBI) compare
b1860 ruvB -1.2 -1.2 Holliday junction DNA helicase B (NCBI) compare
b0953 rmf -1.2 -2.8 ribosome modulation factor (NCBI) compare
b1607 ydgC -1.2 -1.4 conserved inner membrane protein associated with alginate biosynthesis (NCBI) compare
b2163 yeiL -1.2 -4.8 putative transcriptional regulator (VIMSS) compare
b1382 ynbE -1.1 -1.3 predicted lipoprotein (NCBI) compare
b2288 nuoA -1.1 -2.5 NADH dehydrogenase I chain A (VIMSS) compare
b2911 ssrS -1.1 -1.2 6S regulatory RNA (NCBI) compare
b2375 yfdX -1.1 -4.0 hypothetical protein (NCBI) compare
b0142 folK -1.1 -0.6 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) compare
b0623 cspE -1.1 -1.3 cold shock protein E (NCBI) compare
b0101 yacG -1.1 -1.7 zinc-binding protein (NCBI) compare
b3169 nusA -1.1 -1.8 transcription elongation factor NusA (NCBI) compare
b3761 trpT -1.1 -1.3 tRNA-Trp (NCBI) compare
b0740 tolB -1.0 -2.9 translocation protein TolB precursor (NCBI) compare
b4201 priB -1.0 -2.0 primosomal replication protein N (NCBI) compare
b0114 aceE -1.0 -1.8 pyruvate dehydrogenase subunit E1 (NCBI) compare
b1161 ycgX -1.0 -0.9 hypothetical protein (NCBI) compare
b0907 serC -1.0 -3.8 phosphoserine aminotransferase (NCBI) compare
b1863 ruvC -1.0 -1.9 Holliday junction resolvase (NCBI) compare
b3726 pstA -1.0 -2.8 phosphate transporter subunit (NCBI) compare
b2281 nuoI -1.0 -1.9 NADH dehydrogenase subunit I (NCBI) compare
b4570 lomR -1.0 -1.7 no description compare
b1773 ydjI -1.0 -2.4 predicted aldolase (NCBI) compare
b2652 ileY -0.9 -1.3 tRNA-Ile (NCBI) compare
b4513 kdpF -0.9 -1.6 potassium ion accessory transporter subunit (NCBI) compare
b2289 lrhA -0.9 -5.0 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) compare
b2475 ypfJ -0.9 -4.3 hypothetical protein (NCBI) compare
b1677 lpp -0.9 -1.0 murein lipoprotein (NCBI) compare
b4101 phnG -0.9 -2.2 carbon-phosphorus lyase complex subunit (NCBI) compare
b4545 ypdJ -0.9 -2.0 no description compare
b0890 ftsK -0.9 -3.7 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b1968 yedV -0.9 -3.0 predicted sensory kinase in two-component regulatory system with YedW (NCBI) compare
b1579 intQ -0.9 -3.4 Qin prophage; predicted defective integrase (RefSeq) compare
b1707 ydiV -0.9 -2.8 hypothetical protein (NCBI) compare
b2209 eco -0.9 -1.7 ecotin precursor (NCBI) compare
b1253 yciA -0.9 -1.7 predicted hydrolase (NCBI) compare
b3203 yhbH -0.9 -1.7 predicted ribosome-associated, sigma 54 modulation protein (NCBI) compare
b1536 ydeI -0.9 -1.4 hypothetical protein (NCBI) compare
b0658 ybeX -0.9 -1.4 predicteed ion transport (NCBI) compare
b2814 metZ -0.9 -1.2 tRNA-Met (NCBI) compare
b2274 yfbO -0.9 -2.6 predicted protein (RefSeq) compare
b2287 nuoB -0.8 -1.8 NADH dehydrogenase subunit B (NCBI) compare
b4701 sokX -0.8 -0.5 sok-related sRNA, function unknown (RefSeq) compare
b3806 cyaA -0.8 -3.0 adenylate cyclase (NCBI) compare
b1332 ynaJ -0.8 -0.5 predicted inner membrane protein (NCBI) compare
b1530 marR -0.8 -1.8 multiple antibiotic resistance protein; repressor of mar operon (VIMSS) compare
b1686 ydiI -0.8 -1.9 hypothetical protein (NCBI) compare
b4594 ymgJ -0.8 -1.3 hypothetical protein (RefSeq) compare
b2479 gcvR -0.8 -2.0 transcriptional regulation of gcv operon (VIMSS) compare
b4613 dinQ -0.8 -1.2 Damage inducible, function unknown (RefSeq) compare
b1129 phoQ -0.8 -1.7 sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) compare
b2822 recC -0.8 -3.2 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b0136 yadK -0.8 -3.1 predicted fimbrial-like adhesin protein (NCBI) compare
b1690 ydiM -0.8 -2.5 predicted transporter (NCBI) compare
b2390 ypeC -0.8 -1.8 hypothetical protein (NCBI) compare
b1533 ydeD -0.8 -1.7 orf, hypothetical protein (VIMSS) compare
b0523 purE -0.8 -2.5 phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) compare
b0178 hlpA -0.8 -1.2 periplasmic chaperone (NCBI) compare
b3624 rfaZ -0.8 -2.2 lipopolysaccharide core biosynthesis protein (NCBI) compare
b3162 deaD -0.8 -2.3 inducible ATP-independent RNA helicase (VIMSS) compare
b1368 ynaA -0.8 -1.7 Rac prophage; predicted tail protein (RefSeq) compare
b2476 purC -0.8 -1.8 phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) compare
b0440 hupB -0.8 -2.6 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b0741 pal -0.8 -2.1 peptidoglycan-associated outer membrane lipoprotein (NCBI) compare
b2237 inaA -0.8 -1.0 hypothetical protein (NCBI) compare
b1490 yddV -0.8 -2.6 predicted diguanylate cyclase (RefSeq) compare
b0002 thrA -0.8 -4.9 bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) compare
b3941 metF -0.7 -3.3 5,10-methylenetetrahydrofolate reductase (NCBI) compare
b1507 hipA -0.7 -1.9 regulator with hipB (NCBI) compare
b1347 ydaC -0.7 -0.3 Rac prophage; predicted protein (NCBI) compare
b1188 ycgB -0.7 -2.9 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b0013 yaaI -0.7 -3.1 hypothetical protein (NCBI) compare
b1261 trpB -0.7 -1.4 tryptophan synthase subunit beta (NCBI) compare
b0836 yliH -0.7 -1.7 hypothetical protein (NCBI) compare
b2083 yegZ -0.7 -0.6 orf, hypothetical protein (VIMSS) compare
b3620 rfaF -0.7 -2.4 ADP-heptose:LPS heptosyltransferase II (NCBI) compare
b1684 sufA -0.7 -1.4 iron-sulfur cluster assembly scaffold protein (NCBI) compare
b1762 b1762 -0.7 -2.4 orf, hypothetical protein (VIMSS) compare
b3029 ygiN -0.7 -0.8 quinol monooxygenase (NCBI) compare
b1291 sapD -0.7 -1.1 predicted antimicrobial peptide transporter subunit (NCBI) compare
b4695 ykgT -0.7 -0.9 no description compare
b3781 trxA -0.7 -2.0 thioredoxin 1 (VIMSS) compare
b2024 hisA -0.7 -0.6 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) compare
b3164 pnp -0.7 -1.0 polynucleotide phosphorylase/polyadenylase (RefSeq) compare
b2021 hisC -0.7 -3.0 histidinol-phosphate aminotransferase (NCBI) compare
b0073 leuB -0.7 -3.9 3-isopropylmalate dehydrogenase (VIMSS) compare
b4497 yeeL -0.7 -0.5 no description compare
b2499 purM -0.7 -3.6 phosphoribosylaminoimidazole synthetase (NCBI) compare
b3935 priA -0.7 -1.2 primosome assembly protein PriA (NCBI) compare
b0216 aspV -0.7 -1.9 tRNA-Asp (NCBI) compare
b1497 b1497 -0.7 -0.4 putative enzyme (VIMSS) compare
b2428 yfeU -0.7 -2.4 N-acetylmuramic acid-6-phosphate etherase (NCBI) compare
b1285 gmr -0.7 -2.5 modulator of Rnase II stability (NCBI) compare
b2410 yfeH -0.7 -1.9 predicted inner membrane protein (NCBI) compare
b1839 yebY -0.7 -1.9 hypothetical protein (NCBI) compare
b1290 sapF -0.7 -0.9 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1753 ynjA -0.7 -0.7 hypothetical protein (NCBI) compare
b2282 nuoH -0.7 -1.5 NADH dehydrogenase subunit H (NCBI) compare
b0705 ybfL -0.7 -0.4 putative receptor protein (VIMSS) compare
b1348 lar -0.7 -1.0 Rac prophage; restriction alleviation protein (NCBI) compare
b1667 ydhR -0.7 -1.4 hypothetical protein (NCBI) compare
b2003 yeeT -0.6 -1.3 CP4-44 prophage; predicted protein (NCBI) compare
b2603 yfiR -0.6 -3.0 hypothetical protein (NCBI) compare
b0522 purK -0.6 -3.3 phosphoribosylaminoimidazole carboxylase (NCBI) compare
b4494 arpB -0.6 -1.6 no description compare
b0386 proC -0.6 -2.1 pyrroline-5-carboxylate reductase (NCBI) compare
b4294 insA-7 -0.6 -0.8 KpLE2 phage-like element; IS1 repressor protein InsA (NCBI) compare
b3628 rfaB -0.6 -3.6 UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase (RefSeq) compare
b4414 tff -0.6 -1.4 unknown RNA (NCBI) compare
b1152 ymfP -0.6 -2.6 orf, hypothetical protein (VIMSS) compare
b1567 intK -0.6 -1.3 Qin prophage; predicted protein (RefSeq) compare
b3960 argH -0.6 -3.7 argininosuccinate lyase (NCBI) compare
b1726 yniB -0.6 -0.9 predicted inner membrane protein (NCBI) compare
b2026 hisI -0.6 -2.6 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) compare
b3426 glpD -0.6 -2.1 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b1692 ydiB -0.6 -1.9 quinate/shikimate 5-dehydrogenase, NAD(P)-binding (NCBI) compare
b2913 serA -0.6 -2.5 D-3-phosphoglycerate dehydrogenase (NCBI) compare
b3842 rfaH -0.6 -2.3 transcriptional activator RfaH (NCBI) compare
b1062 pyrC -0.6 -2.7 dihydroorotase (NCBI) compare
b4118 melR -0.6 -3.7 DNA-binding transcriptional dual regulator (NCBI) compare
b1669 ydhT -0.6 -1.0 hypothetical protein (NCBI) compare
b3042 b3042 -0.6 -1.1 orf, hypothetical protein (VIMSS) compare
b3688 yidQ -0.6 -2.9 orf, hypothetical protein (VIMSS) compare
b1951 rcsA -0.6 -1.0 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b3630 rfaP -0.6 -3.8 kinase that phosphorylates core heptose of lipopolysaccharide (NCBI) compare
b2071 yegJ -0.6 -1.0 hypothetical protein (NCBI) compare
b0737 tolQ -0.6 -1.5 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2557 purL -0.6 -3.4 phosphoribosylformylglycinamidine synthase (NCBI) compare
b0005 yaaX -0.6 -1.8 hypothetical protein (NCBI) compare
b1346 ydaQ -0.6 -0.8 orf, hypothetical protein (VIMSS) compare
b3771 ilvD -0.6 -4.0 dihydroxy-acid dehydratase (NCBI) compare
b2528 iscA -0.6 -0.8 iron-sulfur cluster assembly protein (NCBI) compare
b1150 ymfR -0.6 -0.5 e14 prophage; predicted protein (NCBI) compare
b4215 ytfI -0.6 -1.1 hypothetical protein (NCBI) compare
b4313 fimE -0.6 -2.9 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b1104 ycfL -0.6 -1.0 hypothetical protein (NCBI) compare
b1783 yeaG -0.6 -3.0 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b1485 ddpC -0.6 -1.5 D-ala-D-ala transporter subunit (NCBI) compare


Specific Phenotypes

For 8 genes in this experiment

For carbon source Ying_Others16 in Escherichia coli BW25113

For carbon source Ying_Others16 across organisms