Experiment set57IT016 for Escherichia coli BW25113

Compare to:

Ying_Others16 rep A; time point 1

200 most important genes:

  gene name fitness t score description  
b3169 nusA -4.0 -4.8 transcription elongation factor NusA (NCBI) compare
b2567 rnc -3.4 -2.0 ribonuclease III (NCBI) compare
b3979 thrT -3.3 -0.9 tRNA-Thr (NCBI) compare
b1332 ynaJ -2.8 -1.1 predicted inner membrane protein (NCBI) compare
b2846 yqeH -2.6 -1.2 orf, hypothetical protein (VIMSS) compare
b2531 iscR -2.5 -2.5 DNA-binding transcriptional repressor (NCBI) compare
b2894 xerD -2.5 -1.5 site-specific tyrosine recombinase XerD (NCBI) compare
b3290 trkA -2.3 -3.7 potassium transporter peripheral membrane component (NCBI) compare
b0730 mngR -2.1 -2.8 DNA-binding transcriptional dual regulator, fatty-acyl-binding (NCBI) compare
b2820 recB -2.0 -2.0 exonuclease V (RecBCD complex), beta subunit (NCBI) compare
b2504 yfgG -2.0 -2.6 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
b0564 appY -1.9 -1.0 DLP12 prophage; DNA-binding transcriptional activator (NCBI) compare
b1551 b1551 -1.9 -1.0 orf, hypothetical protein (VIMSS) compare
b3390 aroK -1.9 -1.8 shikimate kinase I (NCBI) compare
b1861 ruvA -1.8 -2.3 Holliday junction DNA helicase motor protein (NCBI) compare
b1058 yceO -1.8 -0.7 hypothetical protein (NCBI) compare
b2279 nuoK -1.7 -1.6 NADH dehydrogenase subunit K (NCBI) compare
b1882 cheY -1.7 -0.8 chemotaxis regulator transmitting signal to flagellar motor component (NCBI) compare
b0688 pgm -1.7 -3.7 phosphoglucomutase (NCBI) compare
b0990 cspG -1.7 -1.1 DNA-binding transcriptional regulator (NCBI) compare
b1951 rcsA -1.7 -2.2 DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) compare
b1480 sra -1.7 -1.4 30S ribosomal subunit protein S22 (NCBI) compare
b3609 secB -1.6 -2.4 export protein SecB (NCBI) compare
b2652 ileY -1.6 -1.5 tRNA-Ile (NCBI) compare
b4458 oxyS -1.6 -1.3 global regulatory RNA (NCBI) compare
b1557 cspB -1.6 -2.2 Qin prophage; cold shock protein (NCBI) compare
b2479 gcvR -1.6 -3.7 transcriptional regulation of gcv operon (VIMSS) compare
b1545 pinQ -1.5 -0.4 Qin prophage; predicted site-specific recombinase (NCBI) compare
b1860 ruvB -1.5 -1.2 Holliday junction DNA helicase B (NCBI) compare
b2853 ygeI -1.5 -0.7 hypothetical protein (NCBI) compare
b1182 hlyE -1.5 -1.0 hemolysin E (VIMSS) compare
b4685 yrbN -1.4 -2.7 expressed protein (RefSeq) compare
b3120 yhaB -1.4 -1.0 orf, hypothetical protein (VIMSS) compare
b0683 fur -1.4 -1.2 ferric uptake regulator (NCBI) compare
b3426 glpD -1.4 -4.0 sn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding (NCBI) compare
b2433 b2433 -1.4 -2.2 orf, hypothetical protein (VIMSS) compare
b0145 dksA -1.4 -1.7 DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) compare
b4552 yrhC -1.4 -0.6 no description compare
b3619 rfaD -1.4 -3.1 ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) compare
b3811 xerC -1.4 -2.8 site-specific tyrosine recombinase XerC (NCBI) compare
b0242 proB -1.4 -4.7 gamma-glutamyl kinase (NCBI) compare
b4239 treC -1.4 -3.0 trehalose-6-P hydrolase (NCBI) compare
b2528 iscA -1.4 -1.9 iron-sulfur cluster assembly protein (NCBI) compare
b0953 rmf -1.4 -2.0 ribosome modulation factor (NCBI) compare
b1165 ymgA -1.3 -0.9 hypothetical protein (NCBI) compare
b1984 asnW -1.3 -1.2 tRNA-Asn (NCBI) compare
b0439 lon -1.3 -3.4 DNA-binding ATP-dependent protease La (NCBI) compare
b0222 lpcA -1.3 -2.4 phosphoheptose isomerase (NCBI) compare
b4172 hfq -1.3 -0.8 RNA-binding protein Hfq (NCBI) compare
b3725 pstB -1.2 -0.9 phosphate transporter subunit (NCBI) compare
b1837 yebW -1.2 -1.7 orf, hypothetical protein (VIMSS) compare
b3621 rfaC -1.2 -3.9 ADP-heptose:LPS heptosyl transferase I (NCBI) compare
b1346 ydaQ -1.2 -1.4 orf, hypothetical protein (VIMSS) compare
b3386 rpe -1.2 -1.1 ribulose-phosphate 3-epimerase (NCBI) compare
b2754 ygbF -1.2 -2.4 orf, hypothetical protein (VIMSS) compare
b3935 priA -1.2 -2.0 primosome assembly protein PriA (NCBI) compare
b1361 ydaW -1.2 -0.5 orf, hypothetical protein (VIMSS) compare
b1103 ycfF -1.2 -1.4 orf, hypothetical protein (VIMSS) compare
b4426 isrA -1.2 -2.6 unknown RNA (NCBI) compare
b3728 pstS -1.1 -3.4 phosphate transporter subunit (NCBI) compare
b4529 ydbJ -1.1 -1.0 hypothetical protein (NCBI) compare
b2021 hisC -1.1 -3.6 histidinol-phosphate aminotransferase (NCBI) compare
b1192 ldcA -1.1 -3.1 L,D-carboxypeptidase A (NCBI) compare
b2188 yejM -1.1 -6.1 predicted hydrolase, inner membrane (NCBI) compare
b3162 deaD -1.1 -3.4 inducible ATP-independent RNA helicase (VIMSS) compare
b1865 nudB -1.1 -1.2 dATP pyrophosphohydrolase (NCBI) compare
b1291 sapD -1.1 -1.4 predicted antimicrobial peptide transporter subunit (NCBI) compare
b2025 hisF -1.1 -1.9 imidazole glycerol phosphate synthase subunit HisF (NCBI) compare
b3052 rfaE -1.0 -3.5 fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) compare
b0658 ybeX -1.0 -1.4 predicteed ion transport (NCBI) compare
b2912 ygfA -1.0 -1.9 putative ligase (VIMSS) compare
b3545 proK -1.0 -1.0 tRNA-Pro (NCBI) compare
b0074 leuA -1.0 -5.1 2-isopropylmalate synthase (NCBI) compare
b0737 tolQ -1.0 -2.0 membrane spanning protein in TolA-TolQ-TolR complex (NCBI) compare
b2286 nuoC -1.0 -2.5 NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) compare
b1150 ymfR -1.0 -0.8 e14 prophage; predicted protein (NCBI) compare
b1936 intG -1.0 -1.0 predicted defective phage integrase (pseudogene) (RefSeq) compare
b4066 yjcF -1.0 -0.6 hypothetical protein (NCBI) compare
b0071 leuD -1.0 -4.1 isopropylmalate isomerase small subunit (NCBI) compare
b0072 leuC -1.0 -6.3 isopropylmalate isomerase large subunit (NCBI) compare
b4590 ybfK -1.0 -0.7 hypothetical protein (RefSeq) compare
b1783 yeaG -1.0 -4.8 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b2414 cysK -1.0 -4.8 cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) compare
b0438 clpX -1.0 -3.2 ATP-dependent protease ATP-binding subunit (NCBI) compare
b1263 trpD -1.0 -2.3 bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) compare
b4191 ulaR -1.0 -2.2 DNA-binding transcriptional dual regulator (NCBI) compare
b0232 yafN -1.0 -0.6 predicted antitoxin of the YafO-YafN toxin-antitoxin system (NCBI) compare
b3463 ftsE -0.9 -0.6 predicted transporter subunit: ATP-binding component of ABC superfamily (NCBI) compare
b4006 purH -0.9 -5.1 bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) compare
b0002 thrA -0.9 -5.5 bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) compare
b2859 ygeO -0.9 -2.2 hypothetical protein (RefSeq) compare
b1290 sapF -0.9 -1.3 predicted antimicrobial peptide transporter subunit (NCBI) compare
b1799 yeaT -0.9 -2.9 putative transcriptional regulator LYSR-type (VIMSS) compare
b4048 yjbM -0.9 -1.4 hypothetical protein (NCBI) compare
b3261 fis -0.9 -1.9 DNA-binding protein Fis (NCBI) compare
b4128 yjdK -0.9 -0.6 hypothetical protein (NCBI) compare
b4613 dinQ -0.9 -1.0 Damage inducible, function unknown (RefSeq) compare
b3774 ilvC -0.9 -6.4 ketol-acid reductoisomerase (NCBI) compare
b0908 aroA -0.9 -3.6 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) compare
b1448 yncA -0.9 -2.0 predicted acyltransferase with acyl-CoA N-acyltransferase domain (NCBI) compare
b0890 ftsK -0.9 -3.4 DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) compare
b0523 purE -0.9 -2.2 phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) compare
b3771 ilvD -0.9 -5.3 dihydroxy-acid dehydratase (NCBI) compare
b1785 yeaI -0.9 -2.6 predicted diguanylate cyclase (NCBI) compare
b4444 rygA -0.9 -3.2 unknown RNA (NCBI) compare
b2020 hisD -0.9 -3.7 histidinol dehydrogenase (NCBI) compare
b4155 yjeA -0.9 -1.0 putative lysyl-tRNA synthetase (VIMSS) compare
b3960 argH -0.9 -4.7 argininosuccinate lyase (NCBI) compare
b0440 hupB -0.9 -4.9 HU, DNA-binding transcriptional regulator, beta subunit (NCBI) compare
b0739 tolA -0.9 -1.7 cell envelope integrity inner membrane protein TolA (NCBI) compare
b1772 b1772 -0.9 -3.6 putative kinase (VIMSS) compare
b1063 yceB -0.9 -2.6 predicted lipoprotein (NCBI) compare
b0243 proA -0.9 -4.3 gamma-glutamyl phosphate reductase (NCBI) compare
b1259 yciG -0.8 -1.5 orf, hypothetical protein (VIMSS) compare
b3839 tatC -0.8 -3.3 TatABCE protein translocation system subunit (NCBI) compare
b0535 fimZ -0.8 -2.4 predicted DNA-binding transcriptional regulator (NCBI) compare
b2476 purC -0.8 -1.7 phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) compare
b0003 thrB -0.8 -4.1 homoserine kinase (NCBI) compare
b0880 cspD -0.8 -1.0 cold shock protein homolog (NCBI) compare
b1536 ydeI -0.8 -1.4 hypothetical protein (NCBI) compare
b4410 ecnA -0.8 -1.0 entericidin A membrane lipoprotein, antidote entericidin B (NCBI) compare
b0136 yadK -0.8 -3.3 predicted fimbrial-like adhesin protein (NCBI) compare
b0957 ompA -0.8 -2.1 outer membrane protein A (3a;II*;G;d) (NCBI) compare
b3631 rfaG -0.8 -5.9 glucosyltransferase I (NCBI) compare
b4698 mgrR -0.8 -2.0 sRNA antisense regulator down regulates YgdQ and EptB, PhoPQ-regulated, Hfq-dependent; affects sensitivity to antimicrobial peptides (RefSeq) compare
b3250 mreC -0.8 -1.4 cell wall structural complex MreBCD transmembrane component MreC (NCBI) compare
b2762 cysH -0.8 -4.1 phosphoadenosine phosphosulfate reductase (NCBI) compare
b1235 rssB -0.8 -3.0 response regulator of RpoS (NCBI) compare
b2935 tktA -0.8 -1.3 transketolase 1, thiamin-binding (NCBI) compare
b3863 polA -0.8 -0.9 DNA polymerase I (NCBI) compare
b1347 ydaC -0.8 -0.3 Rac prophage; predicted protein (NCBI) compare
b2281 nuoI -0.8 -1.6 NADH dehydrogenase subunit I (NCBI) compare
b0627 tatE -0.8 -1.5 twin arginine translocase protein E (NCBI) compare
b1138 ymfE -0.8 -1.1 e14 prophage; predicted inner membrane protein (NCBI) compare
b0907 serC -0.8 -2.9 phosphoserine aminotransferase (NCBI) compare
b2022 hisB -0.8 -2.6 imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) compare
b3281 aroE -0.8 -5.3 dehydroshikimate reductase, NAD(P)-binding (NCBI) compare
b1409 ynbB -0.8 -1.0 predicted CDP-diglyceride synthase (NCBI) compare
b3773 ilvY -0.8 -4.2 DNA-binding transcriptional dual regulator (NCBI) compare
b1970 yedX -0.8 -2.9 hypothetical protein (NCBI) compare
b2276 nuoN -0.8 -2.4 NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) compare
b1236 galU -0.8 -2.5 glucose-1-phosphate uridylyltransferase (NCBI) compare
b0386 proC -0.8 -2.5 pyrroline-5-carboxylate reductase (NCBI) compare
b4702 mgtL -0.8 -1.1 regulatory leader peptide for mgtA (NCBI) compare
b0004 thrC -0.8 -3.7 threonine synthase (NCBI) compare
b0630 lipB -0.8 -1.2 protein of lipoate biosynthesis (VIMSS) compare
b4232 fbp -0.7 -3.9 fructose-1,6-bisphosphatase (NCBI) compare
b1082 flgK -0.7 -2.2 flagellar hook-associated protein K (NCBI) compare
b2278 nuoL -0.7 -3.8 NADH dehydrogenase subunit L (NCBI) compare
b1699 ydiS -0.7 -2.3 predicted oxidoreductase with FAD/NAD(P)-binding domain (NCBI) compare
b1232 purU -0.7 -2.5 formyltetrahydrofolate deformylase (NCBI) compare
b0294 ykgK -0.7 -2.3 predicted regulator (NCBI) compare
b1478 adhP -0.7 -1.6 alcohol dehydrogenase (VIMSS) compare
b2289 lrhA -0.7 -3.8 DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) compare
b1188 ycgB -0.7 -3.1 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
b2600 tyrA -0.7 -2.6 fused chorismate mutase T/prephenate dehydrogenase (NCBI) compare
b0310 ykgH -0.7 -1.0 predicted inner membrane protein (NCBI) compare
b2704 srlB -0.7 -1.7 glucitol/sorbitol-specific enzyme IIA component of PTS (NCBI) compare
b3761 trpT -0.7 -1.0 tRNA-Trp (NCBI) compare
b1627 rsxA -0.7 -1.5 Na(+)-translocating NADH-quinone reductase subunit E (NCBI) compare
b2297 pta -0.7 -0.5 phosphate acetyltransferase (NCBI) compare
b3500 gor -0.7 -0.8 glutathione reductase (NCBI) compare
b3941 metF -0.7 -3.5 5,10-methylenetetrahydrofolate reductase (NCBI) compare
b0806 ybiM -0.7 -1.9 orf, hypothetical protein (VIMSS) compare
b3094 exuR -0.7 -2.5 negative regulator of exu regulon, exuT, uxaAC, and uxuB (VIMSS) compare
b2085 b2085 -0.7 -1.9 orf, hypothetical protein (VIMSS) compare
b1205 ychH -0.7 -0.7 predicted inner membrane protein (NCBI) compare
b0522 purK -0.7 -3.3 phosphoribosylaminoimidazole carboxylase (NCBI) compare
b2024 hisA -0.7 -1.5 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) compare
b2429 murP -0.7 -3.5 N-acetylmuramic acid phosphotransfer permease (NCBI) compare
b2329 aroC -0.7 -2.8 chorismate synthase (NCBI) compare
b2642 yfjW -0.7 -0.6 CP4-57 prophage; predicted inner membrane protein (NCBI) compare
b4005 purD -0.7 -3.2 phosphoribosylamine--glycine ligase (NCBI) compare
b2557 purL -0.7 -4.0 phosphoribosylformylglycinamidine synthase (NCBI) compare
b4345 mcrC -0.7 -0.6 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC (NCBI) compare
b2839 lysR -0.7 -2.2 DNA-binding transcriptional dual regulator (NCBI) compare
b1363 trkG -0.7 -0.5 Rac prophage; potassium transporter subunit (NCBI) compare
b4313 fimE -0.7 -3.2 tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) compare
b1810 yoaC -0.7 -2.6 predicted protein (RefSeq) compare
b2284 nuoF -0.7 -1.6 NADH:ubiquinone oxidoreductase, chain F (NCBI) compare
b2277 nuoM -0.7 -2.3 NADH dehydrogenase subunit M (NCBI) compare
b1693 aroD -0.7 -2.5 3-dehydroquinate dehydratase (NCBI) compare
b2763 cysI -0.7 -3.0 sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) compare
b3770 ilvE -0.7 -4.1 branched-chain amino acid aminotransferase (NCBI) compare
b0740 tolB -0.7 -2.0 translocation protein TolB precursor (NCBI) compare
b2822 recC -0.7 -2.2 exonuclease V (RecBCD complex), gamma chain (NCBI) compare
b4593 ymgI -0.7 -0.6 hypothetical protein (RefSeq) compare
b1476 fdnI -0.6 -0.6 formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible (NCBI) compare
b3781 trxA -0.6 -1.6 thioredoxin 1 (VIMSS) compare
b2838 lysA -0.6 -3.7 diaminopimelate decarboxylase, PLP-binding (NCBI) compare
b1518 lsrG -0.6 -1.2 autoinducer-2 (AI-2) modifying protein LsrG (NCBI) compare
b1696 ydiP -0.6 -1.5 predicted DNA-binding transcriptional regulator (NCBI) compare
b2456 cchB -0.6 -2.3 predicted carboxysome structural protein, ethanolamine utilization protein (NCBI) compare
b2340 sixA -0.6 -1.7 phosphohistidine phosphatase (NCBI) compare
b0483 ybaQ -0.6 -2.8 orf, hypothetical protein (VIMSS) compare
b3772 ilvA -0.6 -4.3 threonine dehydratase (NCBI) compare
b4215 ytfI -0.6 -1.3 hypothetical protein (NCBI) compare
b4177 purA -0.6 -1.4 adenylosuccinate synthetase (NCBI) compare
b1859 znuB -0.6 -2.3 high-affinity zinc transporter membrane component (NCBI) compare
b0945 pyrD -0.6 -3.5 dihydroorotate dehydrogenase (NCBI) compare


Specific Phenotypes

For 5 genes in this experiment

For carbon source Ying_Others16 in Escherichia coli BW25113

For carbon source Ying_Others16 across organisms