| | gene | name | fitness | t score | description | |
|---|
| b4388 | serB | -5.4 | -9.3 | 3-phosphoserine phosphatase (NCBI) | compare |
| b4383 | deoB | -5.0 | -13.0 | phosphopentomutase (NCBI) | conserved |
| b0386 | proC | -4.9 | -9.7 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2024 | hisA | -4.6 | -3.8 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b0073 | leuB | -4.6 | -11.7 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b2913 | serA | -4.4 | -12.5 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b0072 | leuC | -4.4 | -15.6 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b0243 | proA | -4.4 | -13.5 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b1260 | trpA | -4.4 | -8.0 | tryptophan synthase subunit alpha (NCBI) | compare |
| b0726 | sucA | -4.3 | -7.2 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b0145 | dksA | -4.1 | -4.0 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b3960 | argH | -4.1 | -16.0 | argininosuccinate lyase (NCBI) | compare |
| b2025 | hisF | -4.0 | -7.1 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b3770 | ilvE | -4.0 | -15.5 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b0049 | apaH | -3.9 | -6.0 | diadenosinetetraphosphatase (NCBI) | compare |
| b1261 | trpB | -3.9 | -3.7 | tryptophan synthase subunit beta (NCBI) | compare |
| b3389 | aroB | -3.9 | -13.2 | 3-dehydroquinate synthase (NCBI) | compare |
| b0004 | thrC | -3.9 | -9.8 | threonine synthase (NCBI) | compare |
| b2019 | hisG | -3.9 | -7.5 | ATP phosphoribosyltransferase (NCBI) | compare |
| b1192 | ldcA | -3.8 | -8.9 | L,D-carboxypeptidase A (NCBI) | compare |
| b2329 | aroC | -3.8 | -8.1 | chorismate synthase (NCBI) | compare |
| b2026 | hisI | -3.8 | -8.2 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b0200 | gmhB | -3.8 | -2.6 | hypothetical protein (NCBI) | compare |
| b2414 | cysK | -3.8 | -12.3 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b3772 | ilvA | -3.8 | -14.3 | threonine dehydratase (NCBI) | compare |
| b3771 | ilvD | -3.8 | -18.0 | dihydroxy-acid dehydratase (NCBI) | compare |
| b2022 | hisB | -3.8 | -9.7 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2020 | hisD | -3.8 | -10.5 | histidinol dehydrogenase (NCBI) | compare |
| b0242 | proB | -3.7 | -7.7 | gamma-glutamyl kinase (NCBI) | compare |
| b0074 | leuA | -3.7 | -13.3 | 2-isopropylmalate synthase (NCBI) | compare |
| b3172 | argG | -3.7 | -14.0 | argininosuccinate synthase (NCBI) | compare |
| b3941 | metF | -3.7 | -16.3 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b3774 | ilvC | -3.7 | -16.7 | ketol-acid reductoisomerase (NCBI) | compare |
| b0071 | leuD | -3.7 | -13.6 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b0002 | thrA | -3.6 | -15.6 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b0907 | serC | -3.6 | -9.6 | phosphoserine aminotransferase (NCBI) | compare |
| b0908 | aroA | -3.6 | -13.3 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b2021 | hisC | -3.5 | -9.3 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b3956 | ppc | -3.5 | -18.7 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b2784 | relA | -3.5 | -12.9 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b1693 | aroD | -3.5 | -10.1 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b1861 | ruvA | -3.4 | -2.6 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b3281 | aroE | -3.4 | -18.3 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b2838 | lysA | -3.3 | -12.8 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b2762 | cysH | -3.1 | -10.1 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b3939 | metB | -3.1 | -12.4 | cystathionine gamma-synthase (NCBI) | compare |
| b4214 | cysQ | -3.1 | -14.7 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b2479 | gcvR | -3.0 | -7.3 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b2750 | cysC | -3.0 | -6.8 | adenylylsulfate kinase (NCBI) | compare |
| b2763 | cysI | -3.0 | -9.4 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b1291 | sapD | -3.0 | -3.4 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b4013 | metA | -3.0 | -10.7 | homoserine O-succinyltransferase (NCBI) | compare |
| b0003 | thrB | -3.0 | -9.2 | homoserine kinase (NCBI) | compare |
| b2764 | cysJ | -2.9 | -13.1 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b2600 | tyrA | -2.8 | -6.8 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b4535 | yniD | -2.7 | -2.6 | predicted protein (RefSeq) | compare |
| b3773 | ilvY | -2.7 | -10.7 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0720 | gltA | -2.7 | -7.6 | citrate synthase (NCBI) | compare |
| b3870 | glnA | -2.6 | -6.3 | glutamine synthetase (NCBI) | compare |
| b0113 | pdhR | -2.6 | -5.9 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b3368 | cysG | -2.6 | -16.2 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b2752 | cysD | -2.6 | -7.6 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b0080 | fruR | -2.6 | -7.5 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0033 | carB | -2.5 | -15.6 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b0990 | cspG | -2.5 | -2.2 | DNA-binding transcriptional regulator (NCBI) | compare |
| b3008 | metC | -2.5 | -12.8 | cystathionine beta-lyase (NCBI) | compare |
| b2820 | recB | -2.5 | -1.7 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b2599 | pheA | -2.4 | -7.1 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b1285 | gmr | -2.4 | -8.2 | modulator of Rnase II stability (NCBI) | compare |
| b0032 | carA | -2.3 | -5.8 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b2839 | lysR | -2.3 | -4.2 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2751 | cysN | -2.3 | -8.1 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b3839 | tatC | -2.3 | -9.6 | TatABCE protein translocation system subunit (NCBI) | compare |
| b3204 | ptsN | -2.2 | -7.7 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b3916 | pfkA | -2.2 | -5.7 | 6-phosphofructokinase (NCBI) | compare |
| b1293 | sapB | -2.1 | -2.4 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3390 | aroK | -2.1 | -3.3 | shikimate kinase I (NCBI) | compare |
| b3957 | argE | -2.1 | -13.4 | acetylornithine deacetylase (NCBI) | compare |
| b2340 | sixA | -2.1 | -4.7 | phosphohistidine phosphatase (NCBI) | compare |
| b3636 | rpmG | -2.1 | -3.3 | 50S ribosomal protein L33 (NCBI) | compare |
| b3671 | ilvB | -2.1 | -12.7 | acetolactate synthase large subunit (NCBI) | compare |
| b4480 | hdfR | -2.0 | -8.1 | transcriptional regulator HdfR (NCBI) | compare |
| b3811 | xerC | -2.0 | -3.3 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b2741 | rpoS | -2.0 | -8.4 | RNA polymerase sigma factor (NCBI) | compare |
| b3781 | trxA | -2.0 | -3.6 | thioredoxin 1 (VIMSS) | compare |
| b1292 | sapC | -2.0 | -4.5 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0739 | tolA | -2.0 | -5.1 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b2818 | argA | -1.9 | -9.1 | N-acetylglutamate synthase (NCBI) | compare |
| b1551 | b1551 | -1.9 | -1.3 | orf, hypothetical protein (VIMSS) | compare |
| b3959 | argB | -1.9 | -12.5 | acetylglutamate kinase (RefSeq) | compare |
| b3726 | pstA | -1.9 | -6.0 | phosphate transporter subunit (NCBI) | compare |
| b2894 | xerD | -1.9 | -1.8 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b3958 | argC | -1.8 | -11.1 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b1058 | yceO | -1.8 | -0.9 | hypothetical protein (NCBI) | compare |
| b1882 | cheY | -1.8 | -1.1 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b2287 | nuoB | -1.7 | -4.8 | NADH dehydrogenase subunit B (NCBI) | compare |
| b1232 | purU | -1.7 | -7.5 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b0014 | dnaK | -1.7 | -3.0 | molecular chaperone DnaK (NCBI) | compare |
| b1783 | yeaG | -1.7 | -6.6 | yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b2603 | yfiR | -1.7 | -7.5 | hypothetical protein (NCBI) | compare |
| b1188 | ycgB | -1.7 | -7.6 | ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b2023 | hisH | -1.7 | -4.8 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b3290 | trkA | -1.7 | -4.0 | potassium transporter peripheral membrane component (NCBI) | compare |
| b3650 | spoT | -1.7 | -6.2 | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | compare |
| b2853 | ygeI | -1.6 | -1.0 | hypothetical protein (NCBI) | compare |
| b3849 | trkH | -1.6 | -9.8 | potassium transporter (NCBI) | compare |
| b1784 | yeaH | -1.6 | -8.2 | yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b3386 | rpe | -1.6 | -1.1 | ribulose-phosphate 3-epimerase (NCBI) | compare |
| b2289 | lrhA | -1.6 | -9.9 | DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) | compare |
| b1860 | ruvB | -1.6 | -1.5 | Holliday junction DNA helicase B (NCBI) | compare |
| b0439 | lon | -1.6 | -6.3 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b0890 | ftsK | -1.6 | -7.1 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b0075 | leuL | -1.6 | -4.0 | leu operon leader peptide (NCBI) | compare |
| b1262 | trpC | -1.6 | -3.8 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b3021 | ygiT | -1.5 | -3.3 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2846 | yqeH | -1.5 | -1.2 | orf, hypothetical protein (VIMSS) | compare |
| b4676 | yoaK | -1.5 | -1.0 | expressed protein (RefSeq) | compare |
| b3764 | yifE | -1.5 | -6.4 | hypothetical protein (NCBI) | compare |
| b3728 | pstS | -1.4 | -4.8 | phosphate transporter subunit (NCBI) | compare |
| b2286 | nuoC | -1.4 | -5.8 | NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) | compare |
| b4155 | yjeA | -1.4 | -1.3 | putative lysyl-tRNA synthetase (VIMSS) | compare |
| b3205 | yhbJ | -1.4 | -3.9 | hypothetical protein (NCBI) | compare |
| b3725 | pstB | -1.4 | -1.0 | phosphate transporter subunit (NCBI) | compare |
| b4505 | insX | -1.4 | -1.7 | predicted IS protein (RefSeq) | compare |
| b2290 | yfbQ | -1.4 | -8.9 | aspartate aminotransferase (NCBI) | compare |
| b1863 | ruvC | -1.4 | -3.4 | Holliday junction resolvase (NCBI) | compare |
| b1351 | racC | -1.4 | -0.9 | Rac prophage; predicted protein (NCBI) | compare |
| b4018 | iclR | -1.3 | -7.4 | repressor of aceBA operon (VIMSS) | compare |
| b0863 | artI | -1.3 | -5.8 | arginine transporter subunit (NCBI) | compare |
| b2283 | nuoG | -1.3 | -6.0 | NADH:ubiquinone oxidoreductase, chain G (RefSeq) | compare |
| b0630 | lipB | -1.3 | -1.7 | protein of lipoate biosynthesis (VIMSS) | compare |
| b3672 | ivbL | -1.3 | -4.6 | ilvB operon leader peptide (NCBI) | compare |
| b2168 | fruK | -1.3 | -1.0 | 1-phosphofructokinase (NCBI) | compare |
| b0015 | dnaJ | -1.3 | -8.0 | chaperone Hsp40, co-chaperone with DnaK (NCBI) | compare |
| b3831 | udp | -1.3 | -8.1 | uridine phosphorylase (NCBI) | conserved |
| b0817 | mntR | -1.3 | -3.6 | DNA-binding transcriptional regulator of mntH (NCBI) | compare |
| b2276 | nuoN | -1.2 | -4.9 | NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) | compare |
| b1263 | trpD | -1.2 | -2.5 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b0767 | ybhE | -1.2 | -5.0 | 6-phosphogluconolactonase (NCBI) | compare |
| b0429 | cyoD | -1.2 | -4.8 | cytochrome o ubiquinol oxidase subunit IV (NCBI) | compare |
| b0737 | tolQ | -1.2 | -2.9 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0738 | tolR | -1.2 | -3.1 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b2567 | rnc | -1.2 | -1.4 | ribonuclease III (NCBI) | compare |
| b2964 | nupG | -1.2 | -8.9 | transport of nucleosides, permease protein (VIMSS) | compare |
| b4414 | tff | -1.2 | -2.1 | unknown RNA (NCBI) | compare |
| b2699 | recA | -1.2 | -1.8 | recombinase A (NCBI) | compare |
| b0440 | hupB | -1.1 | -5.8 | HU, DNA-binding transcriptional regulator, beta subunit (NCBI) | compare |
| b4647 | mokA | -1.1 | -1.0 | no description | compare |
| b0585 | fes | -1.1 | -4.9 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b2278 | nuoL | -1.1 | -6.1 | NADH dehydrogenase subunit L (NCBI) | compare |
| b1138 | ymfE | -1.1 | -1.8 | e14 prophage; predicted inner membrane protein (NCBI) | compare |
| b1506 | yneL | -1.1 | -2.2 | predicted transcriptional regulator (NCBI) | compare |
| b1290 | sapF | -1.1 | -1.9 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1422 | ydcI | -1.1 | -3.7 | putative transcriptional regulator LYSR-type (VIMSS) | compare |
| b0623 | cspE | -1.0 | -2.4 | cold shock protein E (NCBI) | compare |
| b1258 | yciF | -1.0 | -1.3 | hypothetical protein (NCBI) | compare |
| b3082 | ygjM | -1.0 | -1.8 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b4552 | yrhC | -1.0 | -0.8 | no description | compare |
| b0114 | aceE | -1.0 | -2.1 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b1426 | ydcH | -1.0 | -1.8 | orf, hypothetical protein (VIMSS) | compare |
| b0676 | nagC | -1.0 | -5.3 | DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine (NCBI) | compare |
| b0888 | trxB | -1.0 | -3.7 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b2277 | nuoM | -1.0 | -4.4 | NADH dehydrogenase subunit M (NCBI) | compare |
| b1334 | fnr | -1.0 | -2.4 | DNA-binding transcriptional dual regulator, global regulator of anaerobic growth (NCBI) | compare |
| b2614 | grpE | -1.0 | -1.7 | heat shock protein (NCBI) | compare |
| b3236 | mdh | -1.0 | -6.0 | malate dehydrogenase (NCBI) | compare |
| b4177 | purA | -1.0 | -1.8 | adenylosuccinate synthetase (NCBI) | compare |
| b1159 | mcrA | -1.0 | -1.3 | e14 prophage; 5-methylcytosine-specific restriction endonuclease B (NCBI) | compare |
| b1524 | yneH | -1.0 | -1.1 | predicted glutaminase (NCBI) | compare |
| b2652 | ileY | -1.0 | -1.3 | tRNA-Ile (NCBI) | compare |
| b2393 | nupC | -0.9 | -4.9 | nucleoside (except guanosine) transporter (NCBI) | conserved |
| b3162 | deaD | -0.9 | -3.2 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b0142 | folK | -0.9 | -0.7 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b2422 | cysA | -0.9 | -5.5 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b3183 | obgE | -0.9 | -1.0 | GTPase involved in cell partioning and DNA repair (NCBI) | compare |
| b3806 | cyaA | -0.9 | -4.4 | adenylate cyclase (NCBI) | compare |
| b2284 | nuoF | -0.9 | -2.8 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b1836 | yebV | -0.9 | -3.0 | orf, hypothetical protein (VIMSS) | compare |
| b0564 | appY | -0.9 | -1.0 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b3601 | mtlR | -0.9 | -4.6 | DNA-binding repressor (NCBI) | compare |
| b0782 | moaB | -0.9 | -2.3 | molybdopterin biosynthesis protein B (NCBI) | compare |
| b0469 | apt | -0.9 | -5.1 | adenine phosphoribosyltransferase (NCBI) | compare |
| b1025 | ycdT | -0.9 | -1.6 | predicted diguanylate cyclase (NCBI) | compare |
| b4395 | ytjC | -0.9 | -3.1 | phosphoglycerate mutase (NCBI) | compare |
| b1264 | trpE | -0.9 | -2.8 | anthranilate synthase component I (NCBI) | compare |
| b0741 | pal | -0.9 | -3.6 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b2501 | ppk | -0.9 | -5.7 | polyphosphate kinase (NCBI) | compare |
| b3609 | secB | -0.9 | -2.3 | export protein SecB (NCBI) | compare |
| b4101 | phnG | -0.8 | -2.3 | carbon-phosphorus lyase complex subunit (NCBI) | compare |
| b1536 | ydeI | -0.8 | -1.5 | hypothetical protein (NCBI) | compare |
| b1160 | elbA | -0.8 | -0.8 | hypothetical protein (NCBI) | compare |
| b4410 | ecnA | -0.8 | -1.3 | entericidin A membrane lipoprotein, antidote entericidin B (NCBI) | compare |
| b0912 | ihfB | -0.8 | -3.2 | integration host factor subunit beta (NCBI) | compare |
| b4191 | ulaR | -0.8 | -3.1 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3169 | nusA | -0.8 | -1.9 | transcription elongation factor NusA (NCBI) | compare |
| b2110 | yehC | -0.8 | -1.0 | predicted periplasmic pilin chaperone (NCBI) | compare |
| b1382 | ynbE | -0.8 | -1.4 | predicted lipoprotein (NCBI) | compare |
| b1347 | ydaC | -0.8 | -0.4 | Rac prophage; predicted protein (NCBI) | compare |
| b4313 | fimE | -0.8 | -5.1 | tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) | compare |
| b0724 | sdhB | -0.8 | -3.1 | succinate dehydrogenase, FeS subunit (NCBI) | compare |