| | gene | name | fitness | t score | description | |
|---|
| b1192 | ldcA | -6.5 | -9.9 | L,D-carboxypeptidase A (NCBI) | compare |
| b2024 | hisA | -6.5 | -3.2 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b0071 | leuD | -6.2 | -10.3 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b2752 | cysD | -6.2 | -8.1 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b3052 | rfaE | -5.9 | -7.1 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b0678 | nagB | -5.8 | -8.5 | glucosamine-6-phosphate deaminase (NCBI) | compare |
| b0908 | aroA | -5.7 | -16.3 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b0726 | sucA | -5.6 | -3.9 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b2414 | cysK | -5.6 | -12.9 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b0004 | thrC | -5.6 | -10.5 | threonine synthase (NCBI) | compare |
| b3771 | ilvD | -5.5 | -17.9 | dihydroxy-acid dehydratase (NCBI) | compare |
| b2329 | aroC | -5.3 | -9.9 | chorismate synthase (NCBI) | compare |
| b3368 | cysG | -5.3 | -23.1 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b0523 | purE | -5.3 | -5.0 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b2021 | hisC | -5.2 | -9.5 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b4006 | purH | -5.2 | -16.8 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b0073 | leuB | -5.1 | -11.9 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b2025 | hisF | -5.1 | -7.0 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b3619 | rfaD | -5.0 | -6.9 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b3389 | aroB | -4.9 | -16.2 | 3-dehydroquinate synthase (NCBI) | compare |
| b0720 | gltA | -4.9 | -9.7 | citrate synthase (NCBI) | compare |
| b2312 | purF | -4.9 | -10.9 | amidophosphoribosyltransferase (NCBI) | compare |
| b2763 | cysI | -4.9 | -11.5 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b3956 | ppc | -4.9 | -21.3 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b3770 | ilvE | -4.8 | -16.8 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b2022 | hisB | -4.8 | -10.0 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b4005 | purD | -4.8 | -14.7 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b3941 | metF | -4.8 | -12.1 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b0522 | purK | -4.8 | -12.8 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b2913 | serA | -4.7 | -14.8 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b2750 | cysC | -4.7 | -10.2 | adenylylsulfate kinase (NCBI) | compare |
| b3939 | metB | -4.7 | -15.1 | cystathionine gamma-synthase (NCBI) | compare |
| b2600 | tyrA | -4.6 | -10.1 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b3281 | aroE | -4.6 | -19.0 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b0074 | leuA | -4.6 | -11.7 | 2-isopropylmalate synthase (NCBI) | compare |
| b1693 | aroD | -4.6 | -11.3 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b1865 | nudB | -4.6 | -3.4 | dATP pyrophosphohydrolase (NCBI) | compare |
| b3172 | argG | -4.6 | -15.9 | argininosuccinate synthase (NCBI) | compare |
| b3960 | argH | -4.6 | -14.2 | argininosuccinate lyase (NCBI) | compare |
| b2023 | hisH | -4.5 | -6.6 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b0242 | proB | -4.5 | -12.7 | gamma-glutamyl kinase (NCBI) | compare |
| b2762 | cysH | -4.5 | -11.6 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b3621 | rfaC | -4.5 | -10.9 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b2557 | purL | -4.5 | -15.7 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b0072 | leuC | -4.5 | -17.7 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b3774 | ilvC | -4.5 | -18.7 | ketol-acid reductoisomerase (NCBI) | compare |
| b0907 | serC | -4.4 | -10.9 | phosphoserine aminotransferase (NCBI) | compare |
| b2764 | cysJ | -4.4 | -12.4 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b2499 | purM | -4.4 | -6.7 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b1260 | trpA | -4.4 | -5.1 | tryptophan synthase subunit alpha (NCBI) | compare |
| b2020 | hisD | -4.4 | -9.9 | histidinol dehydrogenase (NCBI) | compare |
| b1281 | pyrF | -4.4 | -5.9 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b0145 | dksA | -4.4 | -4.3 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b1261 | trpB | -4.4 | -2.4 | tryptophan synthase subunit beta (NCBI) | compare |
| b3772 | ilvA | -4.4 | -16.6 | threonine dehydratase (NCBI) | compare |
| b2019 | hisG | -4.3 | -7.1 | ATP phosphoribosyltransferase (NCBI) | compare |
| b0243 | proA | -4.3 | -13.7 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0142 | folK | -4.3 | -1.6 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b1285 | gmr | -4.3 | -9.6 | modulator of Rnase II stability (NCBI) | compare |
| b2838 | lysA | -4.3 | -14.5 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b0002 | thrA | -4.3 | -16.8 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b2751 | cysN | -4.2 | -10.0 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b0032 | carA | -4.2 | -7.3 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b3781 | trxA | -4.2 | -7.9 | thioredoxin 1 (VIMSS) | compare |
| b1062 | pyrC | -4.1 | -11.3 | dihydroorotase (NCBI) | compare |
| b4388 | serB | -4.0 | -7.8 | 3-phosphoserine phosphatase (NCBI) | compare |
| b0945 | pyrD | -4.0 | -17.2 | dihydroorotate dehydrogenase (NCBI) | compare |
| b2479 | gcvR | -4.0 | -8.9 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b2476 | purC | -3.9 | -4.3 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b2501 | ppk | -3.9 | -12.7 | polyphosphate kinase (NCBI) | compare |
| b0003 | thrB | -3.9 | -9.9 | homoserine kinase (NCBI) | compare |
| b0386 | proC | -3.9 | -10.2 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b4013 | metA | -3.8 | -7.0 | homoserine O-succinyltransferase (NCBI) | compare |
| b0033 | carB | -3.8 | -16.0 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b3957 | argE | -3.8 | -18.8 | acetylornithine deacetylase (NCBI) | compare |
| b0222 | lpcA | -3.8 | -4.3 | phosphoheptose isomerase (NCBI) | compare |
| b2026 | hisI | -3.7 | -14.6 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b3958 | argC | -3.7 | -15.5 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b3870 | glnA | -3.6 | -6.1 | glutamine synthetase (NCBI) | compare |
| b3773 | ilvY | -3.6 | -11.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b3916 | pfkA | -3.6 | -3.5 | 6-phosphofructokinase (NCBI) | compare |
| b3008 | metC | -3.6 | -15.1 | cystathionine beta-lyase (NCBI) | compare |
| b4214 | cysQ | -3.5 | -14.9 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b3204 | ptsN | -3.5 | -9.4 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b3959 | argB | -3.5 | -12.8 | acetylglutamate kinase (RefSeq) | compare |
| b4245 | pyrB | -3.5 | -11.4 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b0113 | pdhR | -3.4 | -7.0 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b3620 | rfaF | -3.3 | -10.0 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b0738 | tolR | -3.3 | -6.5 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0200 | gmhB | -3.3 | -3.1 | hypothetical protein (NCBI) | compare |
| b3642 | pyrE | -3.3 | -6.7 | orotate phosphoribosyltransferase (NCBI) | compare |
| b0737 | tolQ | -3.2 | -6.1 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b2818 | argA | -3.1 | -9.7 | N-acetylglutamate synthase (NCBI) | compare |
| b2912 | ygfA | -3.0 | -5.2 | putative ligase (VIMSS) | compare |
| b2839 | lysR | -3.0 | -7.0 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2188 | yejM | -3.0 | -13.3 | predicted hydrolase, inner membrane (NCBI) | compare |
| b2784 | relA | -2.9 | -12.4 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b0888 | trxB | -2.8 | -6.4 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b0564 | appY | -2.8 | -1.2 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b0739 | tolA | -2.8 | -7.3 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b0439 | lon | -2.7 | -8.2 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b1232 | purU | -2.6 | -8.6 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b3839 | tatC | -2.6 | -10.5 | TatABCE protein translocation system subunit (NCBI) | compare |
| b2603 | yfiR | -2.6 | -8.1 | hypothetical protein (NCBI) | compare |
| b3169 | nusA | -2.5 | -4.9 | transcription elongation factor NusA (NCBI) | compare |
| b3390 | aroK | -2.5 | -2.8 | shikimate kinase I (NCBI) | compare |
| b2599 | pheA | -2.4 | -5.5 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b3860 | dsbA | -2.4 | -11.1 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b2500 | purN | -2.3 | -8.8 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b3792 | wzxE | -2.3 | -10.1 | O-antigen translocase (NCBI) | compare |
| b0957 | ompA | -2.3 | -4.5 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b3728 | pstS | -2.2 | -5.3 | phosphate transporter subunit (NCBI) | compare |
| b1830 | prc | -2.2 | -7.5 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b1262 | trpC | -2.1 | -3.8 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b0740 | tolB | -2.1 | -5.6 | translocation protein TolB precursor (NCBI) | compare |
| b1361 | ydaW | -2.1 | -1.0 | orf, hypothetical protein (VIMSS) | compare |
| b2330 | yfcB | -2.1 | -2.8 | putative adenine-specific methylase (VIMSS) | compare |
| b2423 | cysW | -2.0 | -7.4 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b4480 | hdfR | -2.0 | -6.7 | transcriptional regulator HdfR (NCBI) | compare |
| b3429 | glgA | -2.0 | -13.4 | glycogen synthase (NCBI) | compare |
| b2422 | cysA | -1.9 | -8.8 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b2820 | recB | -1.9 | -2.5 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b1058 | yceO | -1.9 | -0.9 | hypothetical protein (NCBI) | compare |
| b2424 | cysU | -1.8 | -5.9 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b1291 | sapD | -1.8 | -2.9 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1677 | lpp | -1.8 | -3.1 | murein lipoprotein (NCBI) | compare |
| b2652 | ileY | -1.8 | -1.7 | tRNA-Ile (NCBI) | compare |
| b2911 | ssrS | -1.8 | -2.0 | 6S regulatory RNA (NCBI) | compare |
| b0078 | ilvH | -1.7 | -8.7 | acetolactate synthase small subunit (NCBI) | compare |
| b2340 | sixA | -1.7 | -6.5 | phosphohistidine phosphatase (NCBI) | compare |
| b0114 | aceE | -1.7 | -2.3 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b2853 | ygeI | -1.7 | -1.0 | hypothetical protein (NCBI) | compare |
| b0049 | apaH | -1.7 | -4.8 | diadenosinetetraphosphatase (NCBI) | compare |
| b0077 | ilvI | -1.7 | -10.3 | acetolactate synthase III large subunit (NCBI) | compare |
| b0817 | mntR | -1.7 | -4.3 | DNA-binding transcriptional regulator of mntH (NCBI) | compare |
| b1545 | pinQ | -1.7 | -0.5 | Qin prophage; predicted site-specific recombinase (NCBI) | compare |
| b2531 | iscR | -1.7 | -1.4 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3386 | rpe | -1.6 | -1.1 | ribulose-phosphate 3-epimerase (NCBI) | compare |
| b4177 | purA | -1.6 | -2.1 | adenylosuccinate synthetase (NCBI) | compare |
| b0741 | pal | -1.6 | -4.2 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b0088 | murD | -1.5 | -3.0 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) | compare |
| b2846 | yqeH | -1.5 | -1.1 | orf, hypothetical protein (VIMSS) | compare |
| b3726 | pstA | -1.5 | -4.6 | phosphate transporter subunit (NCBI) | compare |
| b1263 | trpD | -1.5 | -4.3 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b2318 | truA | -1.5 | -3.1 | tRNA pseudouridine synthase A (NCBI) | compare |
| b0075 | leuL | -1.5 | -3.8 | leu operon leader peptide (NCBI) | compare |
| b1165 | ymgA | -1.5 | -1.0 | hypothetical protein (NCBI) | compare |
| b1861 | ruvA | -1.4 | -2.8 | Holliday junction DNA helicase motor protein (NCBI) | compare |
| b0303 | ykgI | -1.4 | -1.0 | orf, hypothetical protein (VIMSS) | compare |
| b3290 | trkA | -1.4 | -3.5 | potassium transporter peripheral membrane component (NCBI) | compare |
| b1160 | elbA | -1.4 | -1.9 | hypothetical protein (NCBI) | compare |
| b2313 | cvpA | -1.4 | -2.5 | membrane protein required for colicin V production (NCBI) | compare |
| b4246 | pyrL | -1.4 | -1.9 | pyrBI operon leader peptide (NCBI) | compare |
| b2290 | yfbQ | -1.4 | -9.8 | aspartate aminotransferase (NCBI) | compare |
| b0677 | nagA | -1.4 | -5.3 | N-acetylglucosamine-6-phosphate deacetylase (NCBI) | compare |
| b3811 | xerC | -1.4 | -2.6 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b3764 | yifE | -1.4 | -4.4 | hypothetical protein (NCBI) | compare |
| b4655 | ythA | -1.4 | -1.4 | expressed protein (RefSeq) | compare |
| b3082 | ygjM | -1.3 | -2.0 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3725 | pstB | -1.3 | -0.9 | phosphate transporter subunit (NCBI) | compare |
| b3247 | cafA | -1.3 | -10.6 | bundles of cytoplasmic filaments (VIMSS) | compare |
| b1784 | yeaH | -1.3 | -7.2 | yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b0683 | fur | -1.3 | -1.6 | ferric uptake regulator (NCBI) | compare |
| b3849 | trkH | -1.3 | -9.1 | potassium transporter (NCBI) | compare |
| b1783 | yeaG | -1.3 | -6.8 | yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b1188 | ycgB | -1.2 | -6.5 | ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b1863 | ruvC | -1.2 | -2.3 | Holliday junction resolvase (NCBI) | compare |
| b3163 | nlpI | -1.2 | -4.6 | hypothetical protein (NCBI) | compare |
| b3398 | yrfF | -1.2 | -3.9 | predicted inner membrane protein (NCBI) | compare |
| b0438 | clpX | -1.2 | -4.8 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b3600 | mtlD | -1.2 | -4.7 | mannitol-1-phosphate 5-dehydrogenase (NCBI) | compare |
| b2288 | nuoA | -1.1 | -3.5 | NADH dehydrogenase I chain A (VIMSS) | compare |
| b0863 | artI | -1.1 | -5.1 | arginine transporter subunit (NCBI) | compare |
| b3162 | deaD | -1.1 | -4.5 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b2287 | nuoB | -1.1 | -2.8 | NADH dehydrogenase subunit B (NCBI) | compare |
| b1292 | sapC | -1.1 | -1.9 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1551 | b1551 | -1.1 | -0.9 | orf, hypothetical protein (VIMSS) | compare |
| b2689 | yqaA | -1.0 | -2.5 | conserved inner membrane protein (NCBI) | compare |
| b3237 | argR | -1.0 | -3.7 | arginine repressor (NCBI) | compare |
| b3021 | ygiT | -1.0 | -2.0 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b0580 | ybdJ | -1.0 | -1.3 | predicted inner membrane protein (NCBI) | compare |
| b0767 | ybhE | -1.0 | -4.2 | 6-phosphogluconolactonase (NCBI) | compare |
| b4128 | yjdK | -1.0 | -0.7 | hypothetical protein (NCBI) | compare |
| b4481 | rffT | -1.0 | -5.1 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b4313 | fimE | -1.0 | -6.1 | tyrosine recombinase/inversion of on/off regulator of fimA (NCBI) | compare |
| b4146 | yjeK | -1.0 | -2.8 | predicted lysine aminomutase (NCBI) | compare |
| b4590 | ybfK | -1.0 | -1.2 | hypothetical protein (RefSeq) | compare |
| b1536 | ydeI | -1.0 | -1.6 | hypothetical protein (NCBI) | compare |
| b3500 | gor | -1.0 | -1.2 | glutathione reductase (NCBI) | compare |
| b0755 | gpmA | -1.0 | -5.0 | phosphoglyceromutase (NCBI) | compare |
| b0585 | fes | -1.0 | -5.7 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b1426 | ydcH | -1.0 | -1.9 | orf, hypothetical protein (VIMSS) | compare |
| b0506 | allR | -1.0 | -3.7 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3671 | ilvB | -1.0 | -7.8 | acetolactate synthase large subunit (NCBI) | compare |
| b1258 | yciF | -1.0 | -1.3 | hypothetical protein (NCBI) | compare |
| b1347 | ydaC | -1.0 | -0.5 | Rac prophage; predicted protein (NCBI) | compare |
| b3443 | yrhA | -1.0 | -1.4 | orf, hypothetical protein (VIMSS) | compare |
| b2289 | lrhA | -0.9 | -6.5 | DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) | compare |
| b4018 | iclR | -0.9 | -5.2 | repressor of aceBA operon (VIMSS) | compare |
| b2814 | metZ | -0.9 | -1.7 | tRNA-Met (NCBI) | compare |