| | gene | name | fitness | t score | description | |
|---|
| b1192 | ldcA | -7.4 | -8.8 | L,D-carboxypeptidase A (NCBI) | compare |
| b0222 | lpcA | -6.7 | -4.6 | phosphoheptose isomerase (NCBI) | compare |
| b2024 | hisA | -6.6 | -3.7 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b0004 | thrC | -5.6 | -11.4 | threonine synthase (NCBI) | compare |
| b2414 | cysK | -5.5 | -14.8 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b3172 | argG | -5.3 | -17.9 | argininosuccinate synthase (NCBI) | compare |
| b2499 | purM | -5.1 | -9.0 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b3621 | rfaC | -5.1 | -9.7 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b4388 | serB | -5.0 | -11.2 | 3-phosphoserine phosphatase (NCBI) | compare |
| b2600 | tyrA | -5.0 | -9.5 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b3389 | aroB | -4.9 | -17.7 | 3-dehydroquinate synthase (NCBI) | compare |
| b2763 | cysI | -4.9 | -16.7 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b3619 | rfaD | -4.9 | -8.1 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b3368 | cysG | -4.8 | -21.1 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b3774 | ilvC | -4.8 | -18.5 | ketol-acid reductoisomerase (NCBI) | compare |
| b4005 | purD | -4.8 | -14.8 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b2021 | hisC | -4.8 | -6.5 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b0243 | proA | -4.8 | -13.9 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b0242 | proB | -4.8 | -8.1 | gamma-glutamyl kinase (NCBI) | compare |
| b1260 | trpA | -4.8 | -11.4 | tryptophan synthase subunit alpha (NCBI) | compare |
| b3771 | ilvD | -4.7 | -18.7 | dihydroxy-acid dehydratase (NCBI) | compare |
| b2329 | aroC | -4.7 | -8.5 | chorismate synthase (NCBI) | compare |
| b2026 | hisI | -4.7 | -11.3 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b3052 | rfaE | -4.7 | -11.0 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b2022 | hisB | -4.7 | -9.9 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2764 | cysJ | -4.7 | -13.3 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b3770 | ilvE | -4.7 | -17.5 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b2025 | hisF | -4.7 | -8.4 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b0002 | thrA | -4.7 | -20.1 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b0073 | leuB | -4.7 | -13.9 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b0908 | aroA | -4.7 | -16.8 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b3281 | aroE | -4.7 | -21.7 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b4006 | purH | -4.6 | -17.5 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b2752 | cysD | -4.6 | -8.3 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b1285 | gmr | -4.6 | -12.0 | modulator of Rnase II stability (NCBI) | compare |
| b0522 | purK | -4.6 | -14.1 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b2557 | purL | -4.6 | -15.5 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b3956 | ppc | -4.5 | -21.0 | phosphoenolpyruvate carboxylase (NCBI) | compare |
| b2312 | purF | -4.5 | -8.4 | amidophosphoribosyltransferase (NCBI) | compare |
| b3960 | argH | -4.5 | -14.5 | argininosuccinate lyase (NCBI) | compare |
| b3941 | metF | -4.4 | -12.5 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b0142 | folK | -4.4 | -1.8 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b2838 | lysA | -4.4 | -15.6 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b2750 | cysC | -4.4 | -10.5 | adenylylsulfate kinase (NCBI) | compare |
| b2762 | cysH | -4.3 | -13.0 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b0072 | leuC | -4.3 | -15.6 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b0074 | leuA | -4.3 | -11.9 | 2-isopropylmalate synthase (NCBI) | compare |
| b3642 | pyrE | -4.3 | -8.3 | orotate phosphoribosyltransferase (NCBI) | compare |
| b0945 | pyrD | -4.3 | -17.7 | dihydroorotate dehydrogenase (NCBI) | compare |
| b1261 | trpB | -4.3 | -6.4 | tryptophan synthase subunit beta (NCBI) | compare |
| b0003 | thrB | -4.2 | -11.1 | homoserine kinase (NCBI) | compare |
| b3939 | metB | -4.2 | -17.0 | cystathionine gamma-synthase (NCBI) | compare |
| b1062 | pyrC | -4.2 | -11.1 | dihydroorotase (NCBI) | compare |
| b3772 | ilvA | -4.1 | -16.6 | threonine dehydratase (NCBI) | compare |
| b2501 | ppk | -4.1 | -15.5 | polyphosphate kinase (NCBI) | compare |
| b0145 | dksA | -4.1 | -6.2 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b0032 | carA | -4.1 | -10.0 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b2751 | cysN | -4.0 | -8.4 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b0386 | proC | -4.0 | -7.4 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b4013 | metA | -4.0 | -8.5 | homoserine O-succinyltransferase (NCBI) | compare |
| b2476 | purC | -4.0 | -7.3 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b0678 | nagB | -4.0 | -8.1 | glucosamine-6-phosphate deaminase (NCBI) | compare |
| b0200 | gmhB | -3.9 | -2.7 | hypothetical protein (NCBI) | compare |
| b3870 | glnA | -3.9 | -6.5 | glutamine synthetase (NCBI) | compare |
| b3773 | ilvY | -3.9 | -13.5 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0071 | leuD | -3.9 | -9.3 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b2913 | serA | -3.8 | -11.3 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b2479 | gcvR | -3.8 | -10.2 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b2020 | hisD | -3.8 | -11.5 | histidinol dehydrogenase (NCBI) | compare |
| b2023 | hisH | -3.8 | -6.4 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b1693 | aroD | -3.8 | -10.4 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b0907 | serC | -3.8 | -10.3 | phosphoserine aminotransferase (NCBI) | compare |
| b3957 | argE | -3.7 | -17.5 | acetylornithine deacetylase (NCBI) | compare |
| b2818 | argA | -3.7 | -15.2 | N-acetylglutamate synthase (NCBI) | compare |
| b3959 | argB | -3.6 | -13.4 | acetylglutamate kinase (RefSeq) | compare |
| b0720 | gltA | -3.6 | -9.5 | citrate synthase (NCBI) | compare |
| b0726 | sucA | -3.6 | -6.1 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b0033 | carB | -3.6 | -17.6 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b0523 | purE | -3.6 | -4.7 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b3958 | argC | -3.5 | -15.1 | N-acetyl-gamma-glutamyl-phosphate reductase (NCBI) | compare |
| b4214 | cysQ | -3.5 | -17.6 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b3916 | pfkA | -3.5 | -4.2 | 6-phosphofructokinase (NCBI) | compare |
| b2019 | hisG | -3.5 | -8.4 | ATP phosphoribosyltransferase (NCBI) | compare |
| b3390 | aroK | -3.5 | -4.2 | shikimate kinase I (NCBI) | compare |
| b4245 | pyrB | -3.4 | -12.7 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b3979 | thrT | -3.4 | -1.4 | tRNA-Thr (NCBI) | compare |
| b3792 | wzxE | -3.4 | -13.1 | O-antigen translocase (NCBI) | compare |
| b2188 | yejM | -3.3 | -13.8 | predicted hydrolase, inner membrane (NCBI) | compare |
| b3620 | rfaF | -3.3 | -9.6 | ADP-heptose:LPS heptosyltransferase II (NCBI) | compare |
| b0741 | pal | -3.2 | -7.7 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b2500 | purN | -3.2 | -10.1 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b0739 | tolA | -3.1 | -7.8 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b0738 | tolR | -3.1 | -6.1 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b2912 | ygfA | -3.0 | -7.2 | putative ligase (VIMSS) | compare |
| b1281 | pyrF | -3.0 | -4.6 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b2603 | yfiR | -2.9 | -10.8 | hypothetical protein (NCBI) | compare |
| b2846 | yqeH | -2.9 | -2.0 | orf, hypothetical protein (VIMSS) | compare |
| b2839 | lysR | -2.9 | -6.7 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0113 | pdhR | -2.9 | -5.1 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b3008 | metC | -2.9 | -13.1 | cystathionine beta-lyase (NCBI) | compare |
| b2784 | relA | -2.8 | -13.8 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b3839 | tatC | -2.8 | -11.1 | TatABCE protein translocation system subunit (NCBI) | compare |
| b0439 | lon | -2.7 | -9.7 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b0957 | ompA | -2.7 | -6.0 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b2424 | cysU | -2.6 | -5.2 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b0630 | lipB | -2.6 | -3.1 | protein of lipoate biosynthesis (VIMSS) | compare |
| b1262 | trpC | -2.6 | -4.5 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b1865 | nudB | -2.6 | -3.2 | dATP pyrophosphohydrolase (NCBI) | compare |
| b1292 | sapC | -2.6 | -5.1 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b2599 | pheA | -2.5 | -5.4 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b0737 | tolQ | -2.5 | -4.9 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b3781 | trxA | -2.5 | -5.5 | thioredoxin 1 (VIMSS) | compare |
| b1232 | purU | -2.5 | -10.9 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b0888 | trxB | -2.3 | -6.4 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b3169 | nusA | -2.3 | -4.3 | transcription elongation factor NusA (NCBI) | compare |
| b3204 | ptsN | -2.3 | -5.8 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b0049 | apaH | -2.2 | -4.6 | diadenosinetetraphosphatase (NCBI) | compare |
| b1551 | b1551 | -2.2 | -1.4 | orf, hypothetical protein (VIMSS) | compare |
| b0740 | tolB | -2.1 | -6.7 | translocation protein TolB precursor (NCBI) | compare |
| b4177 | purA | -2.1 | -1.4 | adenylosuccinate synthetase (NCBI) | compare |
| b3860 | dsbA | -2.0 | -9.0 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b3764 | yifE | -2.0 | -6.7 | hypothetical protein (NCBI) | compare |
| b2820 | recB | -2.0 | -2.7 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b2894 | xerD | -2.0 | -1.9 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b1830 | prc | -2.0 | -8.2 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b3728 | pstS | -2.0 | -5.6 | phosphate transporter subunit (NCBI) | compare |
| b2423 | cysW | -1.9 | -8.3 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b2340 | sixA | -1.9 | -5.6 | phosphohistidine phosphatase (NCBI) | compare |
| b3429 | glgA | -1.9 | -12.5 | glycogen synthase (NCBI) | compare |
| b2330 | yfcB | -1.9 | -2.2 | putative adenine-specific methylase (VIMSS) | compare |
| b1291 | sapD | -1.9 | -3.7 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b2422 | cysA | -1.9 | -10.3 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b4048 | yjbM | -1.9 | -2.2 | hypothetical protein (NCBI) | compare |
| b1984 | asnW | -1.8 | -2.2 | tRNA-Asn (NCBI) | compare |
| b2853 | ygeI | -1.7 | -1.1 | hypothetical protein (NCBI) | compare |
| b1545 | pinQ | -1.7 | -0.6 | Qin prophage; predicted site-specific recombinase (NCBI) | compare |
| b0078 | ilvH | -1.7 | -10.6 | acetolactate synthase small subunit (NCBI) | compare |
| b0114 | aceE | -1.7 | -2.5 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b0077 | ilvI | -1.7 | -11.3 | acetolactate synthase III large subunit (NCBI) | compare |
| b0677 | nagA | -1.7 | -6.6 | N-acetylglucosamine-6-phosphate deacetylase (NCBI) | compare |
| b3811 | xerC | -1.7 | -2.9 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b1182 | hlyE | -1.7 | -1.1 | hemolysin E (VIMSS) | compare |
| b3386 | rpe | -1.7 | -1.1 | ribulose-phosphate 3-epimerase (NCBI) | compare |
| b0075 | leuL | -1.7 | -4.6 | leu operon leader peptide (NCBI) | compare |
| b3021 | ygiT | -1.7 | -3.6 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2567 | rnc | -1.6 | -1.9 | ribonuclease III (NCBI) | compare |
| b2290 | yfbQ | -1.6 | -11.5 | aspartate aminotransferase (NCBI) | compare |
| b4480 | hdfR | -1.6 | -6.9 | transcriptional regulator HdfR (NCBI) | compare |
| b2282 | nuoH | -1.6 | -4.6 | NADH dehydrogenase subunit H (NCBI) | compare |
| b3247 | cafA | -1.5 | -10.7 | bundles of cytoplasmic filaments (VIMSS) | compare |
| b0438 | clpX | -1.4 | -7.8 | ATP-dependent protease ATP-binding subunit (NCBI) | compare |
| b2313 | cvpA | -1.4 | -2.0 | membrane protein required for colicin V production (NCBI) | compare |
| b3725 | pstB | -1.4 | -1.0 | phosphate transporter subunit (NCBI) | compare |
| b0437 | clpP | -1.4 | -6.1 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b4246 | pyrL | -1.4 | -1.6 | pyrBI operon leader peptide (NCBI) | compare |
| b1025 | ycdT | -1.4 | -2.9 | predicted diguanylate cyclase (NCBI) | compare |
| b0890 | ftsK | -1.4 | -6.8 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b0817 | mntR | -1.4 | -4.3 | DNA-binding transcriptional regulator of mntH (NCBI) | compare |
| b3163 | nlpI | -1.4 | -5.4 | hypothetical protein (NCBI) | compare |
| b3726 | pstA | -1.4 | -5.6 | phosphate transporter subunit (NCBI) | compare |
| b4414 | tff | -1.4 | -1.7 | unknown RNA (NCBI) | compare |
| b2652 | ileY | -1.3 | -1.6 | tRNA-Ile (NCBI) | compare |
| b2518 | ndk | -1.3 | -2.5 | nucleoside diphosphate kinase (NCBI) | compare |
| b3237 | argR | -1.3 | -3.8 | arginine repressor (NCBI) | compare |
| b3761 | trpT | -1.3 | -2.4 | tRNA-Trp (NCBI) | compare |
| b3290 | trkA | -1.3 | -3.4 | potassium transporter peripheral membrane component (NCBI) | compare |
| b4481 | rffT | -1.3 | -5.9 | 4-alpha-L-fucosyltransferase (NCBI) | compare |
| b2528 | iscA | -1.3 | -3.4 | iron-sulfur cluster assembly protein (NCBI) | compare |
| b1263 | trpD | -1.2 | -3.6 | bifunctional indole-3-glycerol-phosphate synthase/anthranilate phosphoribosyltransferase (NCBI) | compare |
| b1783 | yeaG | -1.2 | -6.3 | yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b2531 | iscR | -1.2 | -2.0 | DNA-binding transcriptional repressor (NCBI) | compare |
| b3849 | trkH | -1.2 | -9.0 | potassium transporter (NCBI) | compare |
| b4647 | mokA | -1.2 | -1.1 | no description | compare |
| b1709 | btuD | -1.2 | -1.2 | vitamin B12-transporter ATPase (NCBI) | compare |
| b1784 | yeaH | -1.1 | -5.8 | yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b1188 | ycgB | -1.1 | -6.5 | ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b0767 | ybhE | -1.1 | -4.9 | 6-phosphogluconolactonase (NCBI) | compare |
| b3162 | deaD | -1.1 | -5.1 | inducible ATP-independent RNA helicase (VIMSS) | compare |
| b3398 | yrfF | -1.1 | -3.6 | predicted inner membrane protein (NCBI) | compare |
| b3600 | mtlD | -1.1 | -5.0 | mannitol-1-phosphate 5-dehydrogenase (NCBI) | compare |
| b1290 | sapF | -1.1 | -2.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b1536 | ydeI | -1.1 | -1.8 | hypothetical protein (NCBI) | compare |
| b3671 | ilvB | -1.1 | -8.6 | acetolactate synthase large subunit (NCBI) | compare |
| b2286 | nuoC | -1.0 | -4.3 | NADH:ubiquinone oxidoreductase, chain C,D (RefSeq) | compare |
| b1185 | dsbB | -1.0 | -3.3 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b2601 | aroF | -1.0 | -4.1 | 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, tyrosine-repressible (NCBI) | compare |
| b0015 | dnaJ | -1.0 | -6.7 | chaperone Hsp40, co-chaperone with DnaK (NCBI) | compare |
| b1677 | lpp | -1.0 | -2.3 | murein lipoprotein (NCBI) | compare |
| b4146 | yjeK | -1.0 | -3.2 | predicted lysine aminomutase (NCBI) | compare |
| b1347 | ydaC | -1.0 | -0.6 | Rac prophage; predicted protein (NCBI) | compare |
| b0623 | cspE | -1.0 | -2.6 | cold shock protein E (NCBI) | compare |
| b4018 | iclR | -1.0 | -6.0 | repressor of aceBA operon (VIMSS) | compare |
| b0585 | fes | -1.0 | -5.2 | enterobactin/ferric enterobactin esterase (NCBI) | compare |
| b3790 | rffC | -1.0 | -5.0 | TDP-fucosamine acetyltransferase (RefSeq) | compare |
| b0755 | gpmA | -1.0 | -7.0 | phosphoglyceromutase (NCBI) | compare |
| b1264 | trpE | -1.0 | -3.9 | anthranilate synthase component I (NCBI) | compare |
| b4215 | ytfI | -1.0 | -2.2 | hypothetical protein (NCBI) | compare |
| b1161 | ycgX | -0.9 | -1.5 | hypothetical protein (NCBI) | compare |
| b2689 | yqaA | -0.9 | -2.0 | conserved inner membrane protein (NCBI) | compare |
| b0088 | murD | -0.9 | -2.7 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) | compare |