| | gene | name | fitness | t score | description | |
|---|
| b0142 | folK | -4.2 | -1.8 | 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase (NCBI) | compare |
| b1192 | ldcA | -4.0 | -6.7 | L,D-carboxypeptidase A (NCBI) | compare |
| b3870 | glnA | -3.6 | -6.4 | glutamine synthetase (NCBI) | compare |
| b3619 | rfaD | -3.2 | -8.1 | ADP-L-glycero-D-mannoheptose-6-epimerase, NAD(P)-binding (NCBI) | compare |
| b0439 | lon | -3.2 | -9.7 | DNA-binding ATP-dependent protease La (NCBI) | compare |
| b0957 | ompA | -3.1 | -5.0 | outer membrane protein A (3a;II*;G;d) (NCBI) | compare |
| b2025 | hisF | -3.0 | -6.0 | imidazole glycerol phosphate synthase subunit HisF (NCBI) | compare |
| b0145 | dksA | -2.9 | -6.2 | DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein (NCBI) | compare |
| b4232 | fbp | -2.9 | -16.8 | fructose-1,6-bisphosphatase (NCBI) | compare |
| b1260 | trpA | -2.9 | -9.2 | tryptophan synthase subunit alpha (NCBI) | compare |
| b0907 | serC | -2.9 | -11.9 | phosphoserine aminotransferase (NCBI) | compare |
| b2414 | cysK | -2.9 | -15.3 | cysteine synthase A, O-acetylserine sulfhydrolase A subunit (NCBI) | compare |
| b0908 | aroA | -2.8 | -10.9 | 3-phosphoshikimate 1-carboxyvinyltransferase (NCBI) | compare |
| b4006 | purH | -2.8 | -14.4 | bifunctionalphosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (NCBI) | compare |
| b2279 | nuoK | -2.8 | -3.5 | NADH dehydrogenase subunit K (NCBI) | compare |
| b0242 | proB | -2.8 | -8.3 | gamma-glutamyl kinase (NCBI) | compare |
| b3281 | aroE | -2.8 | -19.7 | dehydroshikimate reductase, NAD(P)-binding (NCBI) | compare |
| b3770 | ilvE | -2.7 | -15.4 | branched-chain amino acid aminotransferase (NCBI) | compare |
| b0049 | apaH | -2.7 | -5.8 | diadenosinetetraphosphatase (NCBI) | compare |
| b0945 | pyrD | -2.7 | -13.3 | dihydroorotate dehydrogenase (NCBI) | compare |
| b3169 | nusA | -2.7 | -4.4 | transcription elongation factor NusA (NCBI) | compare |
| b3941 | metF | -2.7 | -13.3 | 5,10-methylenetetrahydrofolate reductase (NCBI) | compare |
| b3774 | ilvC | -2.6 | -18.6 | ketol-acid reductoisomerase (NCBI) | compare |
| b0071 | leuD | -2.6 | -13.4 | isopropylmalate isomerase small subunit (NCBI) | compare |
| b3389 | aroB | -2.6 | -14.7 | 3-dehydroquinate synthase (NCBI) | compare |
| b2913 | serA | -2.6 | -14.1 | D-3-phosphoglycerate dehydrogenase (NCBI) | compare |
| b2021 | hisC | -2.6 | -7.6 | histidinol-phosphate aminotransferase (NCBI) | compare |
| b0004 | thrC | -2.6 | -10.6 | threonine synthase (NCBI) | compare |
| b2024 | hisA | -2.6 | -4.9 | N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS) | compare |
| b2188 | yejM | -2.6 | -13.7 | predicted hydrolase, inner membrane (NCBI) | compare |
| b0074 | leuA | -2.6 | -14.6 | 2-isopropylmalate synthase (NCBI) | compare |
| b3939 | metB | -2.5 | -13.3 | cystathionine gamma-synthase (NCBI) | compare |
| b2020 | hisD | -2.5 | -13.3 | histidinol dehydrogenase (NCBI) | compare |
| b0739 | tolA | -2.5 | -6.1 | cell envelope integrity inner membrane protein TolA (NCBI) | compare |
| b1291 | sapD | -2.5 | -3.2 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b3771 | ilvD | -2.5 | -16.5 | dihydroxy-acid dehydratase (NCBI) | compare |
| b0243 | proA | -2.5 | -12.8 | gamma-glutamyl phosphate reductase (NCBI) | compare |
| b4214 | cysQ | -2.5 | -13.4 | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase (NCBI) | compare |
| b1062 | pyrC | -2.5 | -11.0 | dihydroorotase (NCBI) | compare |
| b4388 | serB | -2.5 | -10.0 | 3-phosphoserine phosphatase (NCBI) | compare |
| b0072 | leuC | -2.5 | -14.3 | isopropylmalate isomerase large subunit (NCBI) | compare |
| b0386 | proC | -2.5 | -8.5 | pyrroline-5-carboxylate reductase (NCBI) | compare |
| b2600 | tyrA | -2.5 | -10.1 | fused chorismate mutase T/prephenate dehydrogenase (NCBI) | compare |
| b2501 | ppk | -2.5 | -13.3 | polyphosphate kinase (NCBI) | compare |
| b2476 | purC | -2.5 | -6.2 | phosphoribosylaminoimidazole-succinocarboxamidesynthase (NCBI) | compare |
| b3839 | tatC | -2.5 | -10.2 | TatABCE protein translocation system subunit (NCBI) | compare |
| b2022 | hisB | -2.4 | -11.9 | imidazoleglycerolphosphate dehydratase and histidinol-phosphate phosphatase (VIMSS) | compare |
| b2838 | lysA | -2.4 | -11.5 | diaminopimelate decarboxylase, PLP-binding (NCBI) | compare |
| b0002 | thrA | -2.4 | -16.2 | bifunctional aspartokinase I/homeserine dehydrogenase I (NCBI) | compare |
| b1281 | pyrF | -2.4 | -7.6 | orotidine 5'-phosphate decarboxylase (NCBI) | compare |
| b0080 | fruR | -2.4 | -9.3 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b4676 | yoaK | -2.4 | -1.4 | expressed protein (RefSeq) | compare |
| b2839 | lysR | -2.4 | -6.9 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b2784 | relA | -2.4 | -13.5 | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | compare |
| b3772 | ilvA | -2.4 | -15.3 | threonine dehydratase (NCBI) | compare |
| b0738 | tolR | -2.4 | -5.9 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b0522 | purK | -2.4 | -12.4 | phosphoribosylaminoimidazole carboxylase (NCBI) | compare |
| b3960 | argH | -2.4 | -15.7 | argininosuccinate lyase (NCBI) | compare |
| b2750 | cysC | -2.4 | -11.4 | adenylylsulfate kinase (NCBI) | compare |
| b1693 | aroD | -2.4 | -8.3 | 3-dehydroquinate dehydratase (NCBI) | compare |
| b0003 | thrB | -2.4 | -10.9 | homoserine kinase (NCBI) | compare |
| b2026 | hisI | -2.3 | -12.9 | bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein (NCBI) | compare |
| b0073 | leuB | -2.3 | -11.6 | 3-isopropylmalate dehydrogenase (VIMSS) | compare |
| b2479 | gcvR | -2.2 | -7.6 | transcriptional regulation of gcv operon (VIMSS) | compare |
| b2019 | hisG | -2.2 | -8.0 | ATP phosphoribosyltransferase (NCBI) | compare |
| b2329 | aroC | -2.2 | -8.1 | chorismate synthase (NCBI) | compare |
| b2499 | purM | -2.2 | -8.1 | phosphoribosylaminoimidazole synthetase (NCBI) | compare |
| b2557 | purL | -2.2 | -13.6 | phosphoribosylformylglycinamidine synthase (NCBI) | compare |
| b2312 | purF | -2.2 | -8.5 | amidophosphoribosyltransferase (NCBI) | compare |
| b2168 | fruK | -2.2 | -1.4 | 1-phosphofructokinase (NCBI) | compare |
| b3773 | ilvY | -2.2 | -13.8 | DNA-binding transcriptional dual regulator (NCBI) | compare |
| b0523 | purE | -2.2 | -7.0 | phosphoribosylaminoimidazole carboxylase catalytic subunit (NCBI) | compare |
| b2023 | hisH | -2.2 | -6.8 | imidazole glycerol phosphate synthase subunit HisH (NCBI) | compare |
| b2762 | cysH | -2.1 | -11.0 | phosphoadenosine phosphosulfate reductase (NCBI) | compare |
| b4013 | metA | -2.1 | -10.9 | homoserine O-succinyltransferase (NCBI) | compare |
| b4005 | purD | -2.1 | -11.5 | phosphoribosylamine--glycine ligase (NCBI) | compare |
| b3008 | metC | -2.1 | -13.5 | cystathionine beta-lyase (NCBI) | compare |
| b0114 | aceE | -2.0 | -2.4 | pyruvate dehydrogenase subunit E1 (NCBI) | compare |
| b3204 | ptsN | -2.0 | -6.1 | sugar-specific enzyme IIA component of PTS (NCBI) | compare |
| b0077 | ilvI | -2.0 | -12.7 | acetolactate synthase III large subunit (NCBI) | compare |
| b2599 | pheA | -2.0 | -7.5 | fused chorismate mutase P/prephenate dehydratase (NCBI) | compare |
| b0683 | fur | -2.0 | -2.9 | ferric uptake regulator (NCBI) | compare |
| b1551 | b1551 | -2.0 | -1.3 | orf, hypothetical protein (VIMSS) | compare |
| b3390 | aroK | -1.9 | -4.3 | shikimate kinase I (NCBI) | compare |
| b4155 | yjeA | -1.9 | -1.3 | putative lysyl-tRNA synthetase (VIMSS) | compare |
| b3172 | argG | -1.9 | -12.0 | argininosuccinate synthase (NCBI) | compare |
| b0078 | ilvH | -1.9 | -9.3 | acetolactate synthase small subunit (NCBI) | compare |
| b3642 | pyrE | -1.9 | -7.9 | orotate phosphoribosyltransferase (NCBI) | compare |
| b4245 | pyrB | -1.9 | -11.9 | aspartate carbamoyltransferase catalytic subunit (NCBI) | compare |
| b3429 | glgA | -1.8 | -11.8 | glycogen synthase (NCBI) | compare |
| b1830 | prc | -1.8 | -8.3 | carboxy-terminal protease for penicillin-binding protein 3 (NCBI) | compare |
| b1058 | yceO | -1.8 | -1.0 | hypothetical protein (NCBI) | compare |
| b0033 | carB | -1.8 | -14.5 | carbamoyl-phosphate synthase large subunit (NCBI) | compare |
| b1292 | sapC | -1.8 | -3.4 | predicted antimicrobial peptide transporter subunit (NCBI) | compare |
| b0741 | pal | -1.7 | -4.6 | peptidoglycan-associated outer membrane lipoprotein (NCBI) | compare |
| b2763 | cysI | -1.7 | -10.7 | sulfite reductase, beta subunit, NAD(P)-binding, heme-binding (NCBI) | compare |
| b2424 | cysU | -1.7 | -4.2 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b1261 | trpB | -1.7 | -2.9 | tryptophan synthase subunit beta (NCBI) | compare |
| b1882 | cheY | -1.7 | -1.2 | chemotaxis regulator transmitting signal to flagellar motor component (NCBI) | compare |
| b0740 | tolB | -1.7 | -6.8 | translocation protein TolB precursor (NCBI) | compare |
| b0726 | sucA | -1.7 | -4.4 | alpha-ketoglutarate decarboxylase (NCBI) | compare |
| b3236 | mdh | -1.7 | -10.4 | malate dehydrogenase (NCBI) | compare |
| b2764 | cysJ | -1.7 | -9.4 | sulfite reductase, alpha subunit, flavoprotein (NCBI) | compare |
| b3368 | cysG | -1.6 | -13.1 | fused siroheme synthase 1,3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase/uroporphyrinogen methyltransferase (NCBI) | compare |
| b2853 | ygeI | -1.6 | -1.1 | hypothetical protein (NCBI) | compare |
| b3621 | rfaC | -1.6 | -8.0 | ADP-heptose:LPS heptosyl transferase I (NCBI) | compare |
| b0721 | sdhC | -1.6 | -6.9 | succinate dehydrogenase cytochrome b556 large membrane subunit (NCBI) | compare |
| b2340 | sixA | -1.6 | -5.3 | phosphohistidine phosphatase (NCBI) | compare |
| b1545 | pinQ | -1.6 | -0.6 | Qin prophage; predicted site-specific recombinase (NCBI) | compare |
| b0724 | sdhB | -1.5 | -7.7 | succinate dehydrogenase, FeS subunit (NCBI) | compare |
| b4246 | pyrL | -1.5 | -3.1 | pyrBI operon leader peptide (NCBI) | compare |
| b2897 | ygfY | -1.5 | -4.6 | hypothetical protein (NCBI) | compare |
| b0032 | carA | -1.5 | -7.1 | carbamoyl-phosphate synthase small subunit (NCBI) | compare |
| b4177 | purA | -1.5 | -2.0 | adenylosuccinate synthetase (NCBI) | compare |
| b3021 | ygiT | -1.5 | -2.5 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b3860 | dsbA | -1.5 | -10.4 | periplasmic protein disulfide isomerase I (NCBI) | compare |
| b0723 | sdhA | -1.5 | -9.5 | succinate dehydrogenase flavoprotein subunit (NCBI) | compare |
| b0200 | gmhB | -1.5 | -2.4 | hypothetical protein (NCBI) | compare |
| b1860 | ruvB | -1.5 | -1.6 | Holliday junction DNA helicase B (NCBI) | compare |
| b1951 | rcsA | -1.4 | -2.3 | DNA-binding transcriptional activator, co-regulator with RcsB (NCBI) | compare |
| b1865 | nudB | -1.4 | -3.2 | dATP pyrophosphohydrolase (NCBI) | compare |
| b3811 | xerC | -1.4 | -2.5 | site-specific tyrosine recombinase XerC (NCBI) | compare |
| b1351 | racC | -1.4 | -0.9 | Rac prophage; predicted protein (NCBI) | compare |
| b3052 | rfaE | -1.4 | -6.5 | fused heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase (NCBI) | compare |
| b2751 | cysN | -1.4 | -9.2 | sulfate adenylyltransferase subunit 1 (NCBI) | compare |
| b1262 | trpC | -1.4 | -4.1 | N-(5-phosphoribosyl)anthranilate isomerase and indole-3-glycerolphosphate synthetase (VIMSS) | compare |
| b2894 | xerD | -1.4 | -1.6 | site-specific tyrosine recombinase XerD (NCBI) | compare |
| b2652 | ileY | -1.4 | -1.3 | tRNA-Ile (NCBI) | compare |
| b1232 | purU | -1.4 | -5.7 | formyltetrahydrofolate deformylase (NCBI) | compare |
| b0722 | sdhD | -1.4 | -6.0 | succinate dehydrogenase cytochrome b556 small membrane subunit (NCBI) | compare |
| b3844 | fre | -1.4 | -6.1 | NAD(P)H-flavin reductase (NCBI) | compare |
| b3398 | yrfF | -1.4 | -3.4 | predicted inner membrane protein (NCBI) | compare |
| b0890 | ftsK | -1.4 | -6.2 | DNA-binding membrane protein required for chromosome resolution and partitioning (NCBI) | compare |
| b3781 | trxA | -1.3 | -4.0 | thioredoxin 1 (VIMSS) | compare |
| b2752 | cysD | -1.3 | -6.5 | sulfate adenylyltransferase subunit 2 (NCBI) | compare |
| b2287 | nuoB | -1.3 | -4.7 | NADH dehydrogenase subunit B (NCBI) | compare |
| b0075 | leuL | -1.3 | -5.1 | leu operon leader peptide (NCBI) | compare |
| b3725 | pstB | -1.3 | -0.9 | phosphate transporter subunit (NCBI) | compare |
| b2500 | purN | -1.3 | -6.2 | phosphoribosylglycinamide formyltransferase (NCBI) | compare |
| b2281 | nuoI | -1.3 | -2.6 | NADH dehydrogenase subunit I (NCBI) | compare |
| b0113 | pdhR | -1.3 | -4.7 | transcriptional regulator of pyruvate dehydrogenase complex (NCBI) | compare |
| b2330 | yfcB | -1.3 | -2.3 | putative adenine-specific methylase (VIMSS) | compare |
| b0737 | tolQ | -1.3 | -3.6 | membrane spanning protein in TolA-TolQ-TolR complex (NCBI) | compare |
| b2422 | cysA | -1.2 | -8.2 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b3572 | avtA | -1.2 | -9.0 | valine--pyruvate transaminase (NCBI) | compare |
| b1188 | ycgB | -1.2 | -8.0 | ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | conserved |
| b2282 | nuoH | -1.2 | -3.2 | NADH dehydrogenase subunit H (NCBI) | compare |
| b3163 | nlpI | -1.2 | -6.0 | hypothetical protein (NCBI) | compare |
| b4018 | iclR | -1.2 | -6.8 | repressor of aceBA operon (VIMSS) | compare |
| b4503 | yafF | -1.2 | -1.2 | no description | compare |
| b4146 | yjeK | -1.2 | -3.2 | predicted lysine aminomutase (NCBI) | compare |
| b3386 | rpe | -1.2 | -1.3 | ribulose-phosphate 3-epimerase (NCBI) | compare |
| b2504 | yfgG | -1.1 | -2.1 | Negative regulator of nickel and cobalt uptake (YfgG) (from data) | compare |
| b1161 | ycgX | -1.1 | -1.5 | hypothetical protein (NCBI) | compare |
| b1361 | ydaW | -1.1 | -0.8 | orf, hypothetical protein (VIMSS) | compare |
| b1783 | yeaG | -1.1 | -6.3 | yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | conserved |
| b3261 | fis | -1.1 | -2.9 | DNA-binding protein Fis (NCBI) | compare |
| b2423 | cysW | -1.1 | -4.8 | sulfate/thiosulfate transporter subunit (NCBI) | compare |
| b2689 | yqaA | -1.1 | -3.3 | conserved inner membrane protein (NCBI) | compare |
| b0729 | sucD | -1.1 | -4.5 | succinyl-CoA synthetase subunit alpha (NCBI) | compare |
| b1677 | lpp | -1.1 | -2.8 | murein lipoprotein (NCBI) | compare |
| b3247 | cafA | -1.1 | -8.9 | bundles of cytoplasmic filaments (VIMSS) | compare |
| b1784 | yeaH | -1.1 | -6.2 | yeaH component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) | compare |
| b0888 | trxB | -1.1 | -4.1 | thioredoxin reductase, FAD/NAD(P)-binding (NCBI) | compare |
| b3232 | yhcM | -1.1 | -7.4 | conserved protein with nucleoside triphosphate hydrolase domain (NCBI) | compare |
| b0222 | lpcA | -1.1 | -3.0 | phosphoheptose isomerase (NCBI) | compare |
| b4345 | mcrC | -1.1 | -0.7 | 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC (NCBI) | compare |
| b0767 | ybhE | -1.0 | -4.4 | 6-phosphogluconolactonase (NCBI) | compare |
| b2064 | asmA | -1.0 | -5.6 | predicted assembly protein (NCBI) | compare |
| b2283 | nuoG | -1.0 | -5.6 | NADH:ubiquinone oxidoreductase, chain G (RefSeq) | compare |
| b1285 | gmr | -1.0 | -5.4 | modulator of Rnase II stability (NCBI) | compare |
| b3889 | yiiE | -1.0 | -2.7 | predicted transcriptional regulator (RefSeq) | compare |
| b0088 | murD | -1.0 | -2.5 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamatesynthetase (NCBI) | compare |
| b3838 | tatB | -1.0 | -4.3 | sec-independent translocase (NCBI) | compare |
| b2820 | recB | -1.0 | -1.6 | exonuclease V (RecBCD complex), beta subunit (NCBI) | compare |
| b2313 | cvpA | -1.0 | -2.6 | membrane protein required for colicin V production (NCBI) | compare |
| b3764 | yifE | -0.9 | -4.6 | hypothetical protein (NCBI) | compare |
| b4048 | yjbM | -0.9 | -1.5 | hypothetical protein (NCBI) | compare |
| b3728 | pstS | -0.9 | -3.2 | phosphate transporter subunit (NCBI) | compare |
| b3884 | yihW | -0.9 | -5.9 | putative DEOR-type transcriptional regulator (VIMSS) | compare |
| b1129 | phoQ | -0.9 | -2.0 | sensory histidine kinase in two-compoent regulatory system with PhoP (NCBI) | compare |
| b4054 | tyrB | -0.9 | -7.3 | tyrosine aminotransferase, tyrosine-repressible, PLP-dependent (NCBI) | compare |
| b2289 | lrhA | -0.9 | -7.2 | DNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes (NCBI) | compare |
| b1185 | dsbB | -0.9 | -3.9 | reoxidizes DsbA protein following formation of disulfide bond in P-ring of flagella. (VIMSS) | compare |
| b0728 | sucC | -0.9 | -4.2 | succinyl-CoA synthetase subunit beta (NCBI) | compare |
| b4480 | hdfR | -0.9 | -4.3 | transcriptional regulator HdfR (NCBI) | compare |
| b4552 | yrhC | -0.9 | -0.8 | no description | compare |
| b0437 | clpP | -0.9 | -4.7 | ATP-dependent Clp protease proteolytic subunit (NCBI) | compare |
| b1347 | ydaC | -0.9 | -0.6 | Rac prophage; predicted protein (NCBI) | compare |
| b1060 | yceP | -0.9 | -4.2 | orf, hypothetical protein (VIMSS) | compare |
| b2363 | yfdT | -0.9 | -2.3 | CPS-53 (KpLE1) prophage; predicted protein (NCBI) | compare |
| b2029 | gnd | -0.9 | -6.3 | 6-phosphogluconate dehydrogenase (NCBI) | compare |
| b0564 | appY | -0.9 | -0.7 | DLP12 prophage; DNA-binding transcriptional activator (NCBI) | compare |
| b0953 | rmf | -0.9 | -2.5 | ribosome modulation factor (NCBI) | compare |
| b1409 | ynbB | -0.8 | -1.1 | predicted CDP-diglyceride synthase (NCBI) | compare |
| b1853 | yebK | -0.8 | -3.8 | predicted DNA-binding transcriptional regulator (NCBI) | compare |
| b2284 | nuoF | -0.8 | -3.6 | NADH:ubiquinone oxidoreductase, chain F (NCBI) | compare |
| b2276 | nuoN | -0.8 | -3.9 | NADH:ubiquinone oxidoreductase, membrane subunit N (RefSeq) | compare |
| b3849 | trkH | -0.8 | -6.5 | potassium transporter (NCBI) | compare |
| b2939 | yqgB | -0.8 | -1.8 | predicted protein (RefSeq) | compare |